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CANCER BREAKTHROUGH AS DNA CODE CRACKED


Written by Dr. Welsh, Article reviewed and edited by Dr. Fine M.D..
Published on 13 January 2013

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A NEW era of cancer treatment has dawned.

Scientists from research institutes in Australia, Canada, Japan, China and the UK will today release the first DNA profiles of some of the most prevalent types of tumours.

It is the first output from the International Cancer Genome Consortium of 12 institutes around the world working to map the genes of 50 different cancers.

The Queensland Centre for Medical Genomics at the University of Queensland's Institute of Molecular Bioscience is a member of the consortium and has released the analysed blueprints of two pancreatic tumours.

QCMG director and primary investigator Professor Sean Grimmond said the QCMG was mapping the pancreatic and ovarian tumours of 500 patients, while other institutes were tackling different common cancers, including lung, breast, blood, brain, kidney, liver and stomach.

"Over the last two decades we've worked out that cancer arises from the accumulation of genetic damage to the genome or genetic blueprint . . . once you've accumulated sufficient damage in key locations, tumours will develop," he said.


A MEDICAL DOCTOR TRIES HUMAN GROWTH HORMONE IN 1992


Written by Dr. Welsh, Article reviewed and edited by Dr. Fine M.D..
Published on 10 October 2018

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Dr. Edmund Chein :: Anti-Aging Specialist

One of the most important historical research studies regarding the safety and efficacy of Human Growth Hormone Replacement Therapy is the result of one individual Doctor Edmund Chein. Dr. Chein began his career trained as a health improvement specialist. In 1992 he was 42 years old and he felt that he was steadily declining as a human being. He was gaining weight more quickly than he had in his entire life and he was developing a growing pot belly. Talking to his own health physician, he learned that his own physical health was in danger. His cholesterol levels were abnormally high and his triglyceride levels were much higher than they should have been as well.

Poor Health Decisions and Natural Aging Put Longevity at Risk

Both he and his doctor knew that if he kept treading down the path he was currently taking his quality of life would quickly deteriorate. He knew that he had to change his life when he began experiencing chest pains. Part of him felt like he was too young to be at risk for a heart attack, but as a doctor, he knew that was not the case. His heart troubles led him to a cardiologist, who informed him that he was in grave dangerhis coronary artery was significantly blocked by cholesterol plaques and if the plaque broke off he could easily experience a potentially fatal heart attack. At once, Chein was advised to take medicines in order to control his cholesterol level.

Chein Confident in Hormone Replacement Therapy Approach

Although Chein understood the logic behind such a path, he made the decision to try a much less orthodox approach. As a specialist in physical rehabilitation and medicine, Dr. Chein had utilized Hormone Replacement Therapy for individuals who suffered from unique hormone deficiencies. As a result of Hormone Replacement Treatments, the patients he observed experienced massive benefits to their overall health, with little or no side-effects. He had been intrigued by the Human Growth Hormone Research performed by Dr. Rudman two years earlier and pored over the results with zeal, keeping them nearly memorized in the back of his mind.

HGH Most Promising Form of Hormone Replacement Therapy

There was increasing evidence that other hormones such as DHEA and Melatonin had the ability to alleviate the effects of aging, but nothing seemed to compete with the incredible promise of Human Growth Hormone. Dr. Rudman's study was one of the first of its kinda large scale analysis of the effects of Human Growth Hormone on Adult-HGH Deficiency. Dr. Chein was so confident in the potential of HGH Hormone Replacement Therapy that he made the decision to utilize the treatment himself.

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He was bold in his approachHe wanted to restore all of his primary hormone levels to those of a young man of twenty years old and measure the extent to which HGH Hormone Replacement Therapy could benefit he himself. In the back of his mind, he hoped that by restoring his proper hormone levels he could revert his physiology back to that of a 20 year old man. He felt that if he was physiologically optimized, that his cholesterol and triglyceride levels might normalize, preventing the need for other medications. If he alleviated the effects of aging with Human Growth Hormone, he felt that the medical threats of cardiovascular disease may actually go into remission, eradicating the chest pains that threatened his life.

Dr. Chein Begins Hormone Replacement Therapy

After he made the commitment to Hormone Replacement Therapy, he made an appointment with one of his local fellow physicians in order to diagnose a variety of different hormone levels within his body. After having his blood drawn and professionally tested, he learned that he suffered from multiple hormonal deficiencies, the most severe of which were Testosterone, Human Growth Hormone, DHEA, and Thyroid Hormone.

HGH Hormone Replacement Therapy Works

After having his deficiency diagnosed, he made the decision to restore his levels of these vital hormones to a level which would be normal for a healthy twenty year old, twenty two years younger than himself. Within the next 6 months, his health began to change dramatically. He no longer suffered from that anxiety-induced pain in his chest, and his triglyceride and cholesterol levels normalized, preventing his need for medications to preserve his cardiovascular system. In addition to this, and perhaps partially because, he also began to lose the weight that had accumulated around his paunch.

The doctor who prescribed Dr. Chein's medications was so impressed by the results, that he chose to utilize the hormone treatments as well. He also experienced the beneficial results of Hormone Replacement Therapy featuring Testosterone and Human Growth Hormone.

Hormone Replacement Therapy FAQ

What is DHEA?

DHEA is an intermediary form of sex hormone secreted by both males and females. DHEA is a precursor hormone which can be converted into both Testosterone and Estrogen by the human body. DHEA is primarily released by the adrenal glands. Users of DHEA claim that there are numerous potential benefits to the hormonal supplement. It is believed that DHEA can bolster the immune system, increase energy levels, improve cognition and memory, enhance muscle strength, and optimize adrenal gland function. DHEA may also have the ability to alleviate the symptoms of depression.

What Are the Symptoms of DHEA Deficiency?

There are a number of different potential symptoms associated with Low-DHEA Levels. These include loss of sex drive, anxiety, depression, persistent fatigue and exhaustion, dehydrated eyes, dry skin, brittle hair, sensitivity to audio stimuli, and changes in hair pattern as a result of hair thinning and hair loss.

What is Testosterone?

Testosterone is the primary male hormone, though it is produced in both the male and the female body. In males, Testosterone is known for inducing primary and secondary characteristics both before birth and during puberty. After puberty, Testosterone helps men retain their masculinity, in addition to preserving sexual and cognitive function. Testosterone is released by the Testes and Adrenal Gland in males, and in the Ovaries and Adrenal Gland in females. In both sexes, Testosterone is largely responsible for sexual desire, and Testosterone has other limited yet vital roles to play in female health.

What are the Symptoms of Testosterone Deficiency?

In Males In males, Testosterone Deficiency can hinder the body's ability to generate strong and well-defined muscles. In addition to this, Testosterone Deficiency is generally connected with excess levels of cortisol, which can cause high levels of stress and can lead to cardiovascular complications over time. Testosterone is vital for proper sexual function, and low levels of Testosterone can cause problems ranging from low libido to premature ejaculation and erectile dysfunction. Testosterone also plays a role in mood, and low testosterone levels can cause symptoms of dysthymia and depression.

In Females In women, Testosterone is tightly linked to female sex drive. When women do not have enough Testosterone, their desire for sex can plummet. Testosterone also plays an integral role in female sexual function, and without proper hormonal stimulation, a woman can find herself unprepared physically for sexual activity. In addition to this, there is evidence that Testosterone is linked to both bone health and mental health in female patients.

What is HGH?

Human Growth Hormone is the hormone responsible for general human development and maintenance. HGH is released at its highest levels during puberty, causing drastic changes in height during a period of only a few short years. HGH is released by both the male and female body, and although Testosterone and Estrogen are responsible for sexual differentiation, HGH is responsible for the physical growth of puberty. After puberty, our bodies secrete much less Human Growth Hormone, but it is still a vital hormone which preserves optimal function. After puberty, Human Growth Hormone primarily helps the body sustain and rebuild itself at the cellular level, effecting numerous, if not all, organ and cellular systems within the body.

What Are the Symptoms of HGH Deficiency?

There are a number of significant medical problems that can occur when HGH levels are deficient. Muscle mass starts to atrophy, leaving the muscles both aesthetically and functionally weaker. The skin becomes dehydrated and more prone to wrinkles, lines, and drooping. Over time, HGH Deficiency can lead to osteoporosis and general weakening of the bones. Human Growth Hormone has been linked with general well being, and HGH Deficiency can lead to symptoms of depression and anxiety.

What is Thyroid Hormone?

The Thyroid is the biggest endocrine gland in the human body. It is located in the neck just under the Adam's apple in males and the equivalent area in females. Thyroid Hormone is the primary hormone released by this gland. Thyroid Hormone is responsible for controlling hunger. A low level of Thyroid Hormone is diagnosed as Hypothyroidism. A high level of the hormone is diagnosed as Hyperthyroidism.

What are the Symptoms of Thyroid Hormone Deficiency?

Thyroid Hormone Deficiency prevents the body from feeling properly sated by meals, causing patients to become overweight, with a severity dependent upon the level of deficiency. Although weight gain is the primary symptom of Thyroid Hormone Deficiency, this disorder can also lead to decreased sex drive, memory loss, weakness, fatigue, constipation, and depression, among other medical issues. The human body constantly resides in a state of amplified hunger as a result of deficiency, causing the body to function as though hunger cessation is the most important goal, taxing other systems of the body as a result.

What is the Conscious Evolution Institute?

The purpose of this website is to provide a wide array of information regarding the viability of Hormone Treatments such as Human Growth Hormone HRT and Testosterone HRT as longevity medications meant to alleviate Age-Induced Hormone Deficiency. There are many paths to health, and our goal is to encourage you to become more proactive in preserving your own personal health, regardless of your current medical condition.

There are many roads to good health, whether it be through better diet, exercise, of Hormone Replacement Therapy. If you feel that you may be a candidate for Hormone Replacement Therapy, we encourage you to contact the Conscious Evolution Institute today. We are highly trained in rejuvenative therapies featuring Human Growth Hormone, Testosterone, and numerous other vital hormones and hormone derivatives. We promise to serve you promptly and with care. We look forward to hearing from you!


CHEMICAL POLLUTION IS DESTROYING MASCULINITY


Written by Dr. Welsh, Article reviewed and edited by Dr. Fine M.D..
Published on 07 October 2018

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Endocrine Disrupting Chemicals in Pesticides and Plastics

Over the last ten years, clinical and ecological research continues to suggest that many chemicals, both synthetic and natural, have the ability to disrupt the hormone balance of the endocrine system, producing various negative effects in all sorts of creatures, including birds, fish, wildlife, and even human beings.

When discussing the hormonal implication of these chemicals, scientists and researchers have labeled these chemicals endocrine disruptors. In today's 21st century world, these products are everywhere in our lives. Some of the most common places where these chemicals exist are pesticides, cosmetics, toys, foods, flame retardants, detergents, metal food cans, and some plastic bottles.

Today, there is a limited body of scientific data available regarding these chemicals, but there is a legitimate concern over how these chemicals may have an impact on human health. In the environment, there are areas which are polluted with endocrine disrupting chemicals to an extent that ecological populations are experiencing deleterious effects directly as a result. These negative health impacts have also been proven in a laboratory atmosphere.

Although it is clear that Endocrine Disrupting Chemicals are a health risk under certain circumstances and concentrations, it can be hard to study the health impact of these chemicals, because people are generally exposed to a number of these chemicals at varying concentrations at the same time. There are government and non-profit organizations dedicated to clarifying the health risks and implications associated with Endocrine Disruptors, two of which are the National Toxicology Program and the National Institute of Environmental Health Science.

These groups support and fund scientific studies aimed at fostering a more complete understanding regarding how these chemicals impact hormone balance in an effort to protect both human beings and wildlife from the negative impact of Endocrine Disrupting Chemicals. In the near and distant future, these programs hope to minimize the domestic and global environmental and health impact of these chemicals and to discover ways to mitigate the negative effects.

What is an Endocrine Disrupting Chemical?

Endocrine Disrupting Chemicals are synthetic or naturally occurring chemicals which have the capacity to interfere with the secretion or functional capacity of hormones produced by the endocrine system. These chemicals have the ability to significantly alter hormone balance in both humans and animals, leading directly to negative health consequences. A number of these Endocrine Disruptors have been strongly correlated with immune, neural, reproductive, and developmental issues in both captive and wild animal populations.

Many researchers also believe that these chemicals and compounds also have the ability to negatively impact human health at existing concentrations. There is some correlation between reduced fertility and Endocrine Disrupting Chemicals. These chemicals also appear to increase the risks of certain health conditions, including several cancers.

In addition to Endocrine Disruptors and Endocrine Disrupting Chemicals, these chemicals are also referred to by a number of other names, including Endocrine Active Compounds, Environmental Hormones, and Endocrine Modulators.

There are forms of chemical pollution that affect various types of hormone balance, but the group of chemicals that have received the largest body of scientific study are those that increase the physiological influence of Estrogen. A number of other chemical disruptors have been identified however, including those that encourage the production of thyroid hormones, androgens, and progesterone, and those that inhibit the production of Estrogens and Androgens.

What is the Importance of the Endocrine System?

Along with the Neurological System, the Endocrine system is the primary way that the body communicates changes from disparate areas of the body. The Endocrine System also plays a central role in the coordination and control of numerous physiological functions. The Endocrine System produces these changes directly through the secretion of hormones from Endocrine Tissues situated throughout the body, including the pancreas, thyroid, pituitary, testes, and ovaries. These hormones then enter the blood stream where they flow to target organs and affect change.

Hormones are able to conduct the complex orchestra of necessary functions which keep us happy and healthy. One example of how hormones function is the complex way that the reproductive system, nervous system, fat, liver, gut, and kidneys work together in order to control and maintain various metabolic functions, including:

  • Reproduction

  • Development and Growth

  • Energy Level of the Body

  • Hormone Homeostasis

  • Response to Injury, Stress, and Outside Influences

Endocrine Disrupting Chemicals interfere with the normally-closed set of signals flowing throughout the body to keep us healthy, leading directly to hormone imbalance which causes a variety of negative consequences.

How do Endocrine Disrupting Chemicals Work?

Animal research has provided us with a lot of insight regarding the impact of Endocrine Disrupting Chemicals. There are a number of different mechanisms through which EDCs have the ability to alter the normal function of the human body.

Endocrine Disruptors have the ability to:

  • Substitute partially or completely for hormones produced naturally by the human body, such as Thyroids Hormones, Androgens, and Estrogens. These chemicals imbalance the system by overstimulating the body with the effects of a particular hormone.

  • Block the normal and healthy function of a hormone by blocking cell receptors and preventing hormones from making their connections. In these cases, the target organ does not receive the full physiological signal, and the body displays symptoms and signs of deficiency. Chemicals that produce these effects are categorized under terms such as Anti-Androgens and Anti-Estrogens.

  • Other Endocrine Disruptors actually have the ability to block or alter the way that hormones and hormone receptors are controlled or created. One example is that there are certain EDCs which can prevent the proper metabolism of hormones by the liver.

What are Some Particular Examples of Endocrine Disrupting Chemicals?

There are a large number of chemicals which have the capacity to alter normal Endocrine Function in a variety of ways. A few well known Endocrine Disrupting chemicals are, PCBs, Dioxin, and the medication Diethylstibesterol (also known as DES), and pesticides like DDT .

There are other chemicals, commonly plasticizers and pesticides, which have been shown to have Endocrine Disrupting effects in animal studies, such as Bisphenol A (also known as BPA). Bisphenol A is a synthetic chemical that is in many plastic products such as bottles, which leach from certain products when exposed to heat. BPA has many industrial applications, including the creation of beverage and food containers, and well as an ingredient of resins used in dental sealants.

Another large group of Endocrine Disrupting Chemicals are known as phthalates. The industrial application of these synthetic chemicals is to improve the flexibility or soften plastics made from polyvinyl chloride. One common phthalate is DEHP. This chemical is used in the production of a large number of polyvinyl products such as food packages, clothes, car products, building materials, children's products, and medical tools. Scientists with the National Toxicology Program have found that there may be a link between DEHP and developmental issues in young children, especially male infants which are seriously ill.

Some of the most common forms of naturally occurring Endocrine Disrupting Chemicals are known as Phytoestrogens. These chemicals are naturally produced in some plants, and have the ability to partially mimic the effects of Estrogen under some circumstances. Some of these chemicals can be found in foods and other products produced from soy, such as daidzein and genestein.

Representatives of the National Toxicology Program recognized the importance of evaluating the risks of Endocrine Disrupting Chemicals upon human reproduction, and created The Center for the Evaluation of Risks to Human Reproduction. This group analyzes various products for signs that they may impact normal fetal and childhood development. The Center has determined that seven Phthalate compounds have Endocrine-Disrupting Effects, as well as one particular Phytoestrogen known as Genistein. Genistein is an ingredient in infant formulas derived from soy.

How do People become Exposed to Endocrine Disrupting Chemicals?

There are a number of ways that individuals of all ages can become exposed to EDCs. It can enter through their dietary choices, the medicines they are prescribed, and even the make-up they put on their face. Exposure can occur directly through the skin, through the digestive system, and through breathing.

Many chemicals which have these Endocrine Disrupting qualities take a long time to degrade or otherwise dissipate, such as the pesticide DDT. For this reason, many EDC Chemicals can be a health risk for long after they are initially used.

What is the Current State of Endocrine Disrupting Chemical Research?

The National Institute of Environmental Health Science has spent over thirty years researching the impact of medical Diethylstilbestrol on human patients. This chemical was used from the 1940s to the 1970s because medical professionals mistakenly believed that the chemical had the ability to reduce the risk of miscarriage for patients at serious risk.

In 1972, it was discovered that daughters born to mothers that were treated with DES had a significantly increased risk of experiencing a very uncommon form of vaginal cancer. In addition to this, DES produced many other changes in children of both sexes born to mothers that took the drug. The National Institute of Environmental Health Science performed extensive animal studies which proved the link between exposure to DES and the development of birth defects and increased cancer risk.

Leading directly from this initial, stunning series of discoveries, scientists with the NIEHS have continued to study other chemicals which interact adversely with estrogen receptors. Scientists continue to broaden the body of knowledge regarding Endocrine Disrupting Chemicals in a number of different ways, including:

  • Creating new tools and models to reveal new information about how Endocrine Disruptors function

  • Uncovering new techniques to discover which chemicals produce Endocrine Disrupting Effects

  • Studying the impact of EDC exposure throughout the lifespan, and how it impacts health

  • Studying the effects of EDCs in existing human patient populations

  • Creating new tests and biological markers in order to measure both toxicity level and exposure to these chemicals

  • Animal studies created to assess the effects of EDC exposure

  • Developing ways to treat patients exposed to EDCs or learn ways to prevent exposure

When are Endocrine Disrupting Chemicals Most Dangerous?

Scientific studies show that EDC exposure produces the highest level of risk before a child is born, or in the period after birth in which the organs of the child's body are still developing. In animal studies, there are a number of different issues related to early EDC exposure, including increased cancer risk and reduced fertility, which may not become an issue until a much later point in the lifespan.

In one case, researchers found that animal subjects which were exposed to synthetic BPA or natural, human Estradiol during prenatal development as well as Estradiol during adulthood were much more likely to develop a particular prostate cancer precursor. This study provides evidence that both natural and synthetic estrogen exposure have the ability to impact the way that the prostate behaves at the genetic level, which increases the risk of prostate disorders and cancer.

Low Level Endocrine Disrupting Chemical Disruptor Exposure

Researchers have found that there is credible evidence that EDCs can impact the physiological function of animals even at very low doses. These doses are significantly below what has traditionally been believed to impact health and physiology.

Even though there has been a limited amount of study in regard to the direct impact of EDCs upon human health and function, the body of animal evidence is quite large, and Endocrine Disrupting Chemicals have the ability to cause the following issues in animal populations:

  • Abnormal development of male reproductive organs

  • Drop in male fertility

  • Increased female-to-male birth ratio

  • Increased incidence of sexual issues in female animals, including fertility complications and premature puberty

  • Increased incidence of breast, prostate, and ovarian cancer

  • BPA may also negatively impact diabetes and obesity.

Can Endocrine Disruptors in Pesticides and Plastics Affect Future Generations?

Evidence suggests that Endocrine Disrupting Chemicals not only have a negative impact on individual exposure, but EDC exposure may have a hereditary risk as well. There is some research that provides evidence that a patient exposed to Endocrine Disruptors may pass on their genetic abnormalities to future generations. In laboratory animals, the increased risk of cancer passed on three generations after initial exposure.

Another study found that male laboratory rats exposed to two particular EDCs were found to carry on abnormalities to almost every male in proceeding generations. The researchers hypothesize that these EDCs have the ability to alter gene expression without directly causing genetic mutation.

EDC research is a vastly expanding field, and as our knowledge of the effects of these chemicals continues to grow, it will help us to prevent or mitigate the effects of these chemicals on both human and animal populations.


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