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Introduction to Human Growth Hormone


Written by Dr. Welsh, Published on 30 July 2013

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How does Human Growth Hormone Work?

Human Growth Hormone is one of the most important metabolic hormones secreted by the human body. The hormone itself goes by a few different names. Somatotropin refers to naturally occurring Growth Hormone that is present in all animal species. Somatotropin also refers to medically derived HGH that has been gathered from the pituitary gland of cadavers. At first, this was the only way to utilize HGH for medical use.

Today, however, almost all medical Human Growth Hormone is synthetically derived via a process known as Recombinant DNA Technology. Although the process is synthetic, the Human Growth Hormone created from the process is functionally and biologically identical to the Growth Hormone that your own Pituitary secretes.

HGH derived from Recombinant DNA Technology is also referred to as Somatropin. Another, more commonly used term used to describe Recombinant HGH is Bio-Identical HGH. This term both signifies the different origin of this form of HGH while also recognizing that the hormone created in the laboratory is completely identical to that which is naturally created by the body.

Why do they have different names if they are the same thing?

There are a couple of important reasons. First, there are risks involved with Human Growth Hormone derived from cadavers that are not at play when utilizing Bio-Identical Human Growth Hormone, the most significant of which is Krutzfield-Jacobs Disease. Krutzfield-Jacobs Disease is prion disorder that shares some similarity with Alzheimer's disease. In rare cases, HGH that was harvested from cadavers was tainted with traces of this debilitating disease.

Given the severity of the disease, the use of Harvested HGH for Medical Usage completely ground to a halt, and new techniques to safely create Bio-Identical Human Growth Hormone were invented in order to fill the void. Today, all Hormone Replacement Therapy is conducted using Bio-Identical HGH, so most people do not differentiate between the two forms in everyday speech.

The second reason that the two forms of hormone are named differently is because source also matters for legal reasons. Different companies have legal rights to particular forms of Human Growth Hormone. No company has a legal right to natural Human Growth Hormone, but companies have patents which protect the specific medical techniques that they use in order to synthesize HGH for medical use.

A few of the most common forms of HGH Hormone Replacement Therapy are Nutopin, Humatrope, Saizen, and Norditropin. Today, Human Growth Hormone is incredibly safe, and none of the pitfalls of early forms of HGH are at play any longer, allowing you to experience the pure effects of the treatment.

How is Human Growth Hormone Composed?

Human Growth Hormone is known as a Peptide Hormone. Peptide hormones are made up amino acids chained together by peptide bonds. There are over forty hormones secreted by the human body, and they all have unique and vital purposes in regard to the proper and optimal function of the body. The primary function of Human Growth Hormone is to encourage optimal cellular metabolism throughout the body.

HGH is also known as a mitogen for this reason. Mitogens are chemicals which encourage the the cells of the body to reproduce and divide at an increased rate. Although this sounds like something simple, it is actually incredibly complex. HGH affects every system in the body in a unique way. It makes the muscles grow larger, it strengthens and hardens the bones, and it keeps the immune system running at peak capacity.

Specifically, HGH is a poly-peptide hormone which is comprised of 191 amino acids linked in a specific configuration. Human Growth Hormone weighs 22,124 daltons. A dalton is a unit of molecular weight which is identical to the atomic mass of the molecule. This entire collection of amino acids is linked into one long chain. This chain forms four helix structures which are responsible for the proper function of the cell.

All animal species on the planet have Growth Hormone. Although all species need Growth Hormone to function, every animal has its own unique formulation. Because of these unique differences in structure, the only forms of Growth Hormone which stimulate the human brain are those of human beings themselves, and certain Old World Monkeys. No other form of Growth Hormone produces any affect on the human brain.

Endogenous Human Growth Hormone is produced only in the pituitary gland by tiny organs known as somatotrophs. The somatotrophs are responsible for the manufacture, storage, and release of these hormones. The somatotrophs are located on the outside wings of the pituitary.

There are two genes responsible for the secretion of HGH. These two genes are known as GH-1 and GH-2. The specific location of the Human Growth Hormone genes is on chromosome 17 in region q22-24. Although we have described the primary form of Human Growth Hormone above, the pituitary gland produces smaller amounts of slightly different formulations of HGH which seem to be correlated with specific outside stimuli. Researchers are just beginning to more fully understand the full function of these alternate versions of the HGH Molecule.

How is Human Growth Hormone Regulated?

HGH is primarily controlled by hormones delivered from the Hypothalamus. The region of the hypothalamus responsible for Human Growth Hormone Regulation is known as the Neurosecretory Nuclei. This structure produces a hormone known as Growth Hormone-Releasing Hormone, abbreviated GH-RH. GH-RH is also referred to in some scientific circles as Somatocrinin.

The Neurosecretory Nuclei also releases a hormone which inhibits the production of Human Growth Hormone known as Somatostatin. Somatostatin is also sometimes referred to as Growth Hormone-Inhibiting Hormone, abbreviated GH-IH. These hormones make their way from the Hypothalamus to the Pituitary Gland via a pathway known as the Hypophyseal Portal System. This structure is a series of small blood vessels which directly link the Hypothalamus to the Pituitary Gland.

A second hormone which has been shown to increase the production of Human Growth Hormone is Ghrelin, which is a hunger stimulator.

Although the release of Human Growth Hormone by the pituitary is mainly the result of the interplay of GH-RH and Somatostatin, the release of these hormones are influenced by a number of different outside circumstances.

Human Growth Hormone Stimulators

The following factors are HGH Stimulators:

Healthy Sleep Human Growth Hormone is primarily secreted during the deepest hours of sleep.

Proper Nutrition Healthy nutrition provides the body with all of the equipment that it needs to properly produce HGH. Improper nutrition forces the body to pick and choose which systems receive the limited nutrients available.

Physical Activity The human body secretes significant levels of Human Growth Hormone during vigorous physical activity.

Human Growth Hormone Inhibitors

The following factors are HGH Inhibitors:

  • Poor Sleep This prevents the body from receiving its largest full dosage of Human Growth Hormone each day.

  • Sedentary Lifestyle Without healthy exercise, the body does not produce as much Human Growth Hormone as it should.

  • Excess Fatty Acids High levels of Triglycerides and LDL cholesterol have been shown to decrease the body's ability to properly synthesize HGH.

  • Excess Insulin Production The more Insulin that you produce, the less HGH that your body will secrete.

  • Obesity Excess fat in general limits the body's ability to properly produce Human Growth Hormone.

  • Stress Abnormally high stress levels negatively impact HGH Secretion.

There are also some uncontrollable factors which can have an impact on Human Growth Hormone Production, including gender, heredity, and age.

How is Human Growth Hormone Released?

The Somatotrophs release Human Growth Hormone in pulses when stimulated by the Hypothalamus. The largest pulses of Human Growth Hormone Production occur around an hour after falling asleep. During this period, the body releases 13-72 nanograms/milliliter of HGH into the blood plasma. Aside from this large, primary release of Human Growth Hormone, HGH production is largely unique to the individual, and can also change significantly from day to day.

Almost half of Human Growth Hormone Secretion takes places during the 3rd and 4th stages of deep sleep. During waking hours, HGH secretion peaks every three to five hours. When these peaks occur, the window of HGH secretion can be as high as 45 nanograms/milliliter. Between these highs, base Human Growth Hormone remains very low, less than 5 nanograms/milliliter. It should be clear based off this data that poor sleeping habits can wreck a person's HGH Levels, negatively impacting their health in numerous ways.

HGH and Aging

Human Growth Hormone Production is distinctly correlated with the aging process. Human Growth Hormone is produced at its highest rates during the teenage growth spurt, peaking and lowering to a certain plateau at the end of puberty. During puberty, HGH secretion can reach levels as high as 700 micrograms per day. After puberty, adults normally secrete around 400 micrograms per day.

We continue to produce this healthy level of Adult HGH throughout our late teens and twenties. Beginning in the late twenties or early thirties, the pituitary gland starts to produce less and less Human Growth Hormone. The rate at which this decline occurs is generally between one and two percent each year.

List of Biological HGH Stimulators:

  • GH-RH Growth Hormone-Releasing Hormone binds to GH-RH Receptors in the Pituitary gland.

  • Sex Hormones Testosterone, Estrogen, and other Sex Hormones encourage the release of HGH. Testosterone has been shown to increase the amplitude of HGH Spikes.

  • Ghrelin Ghrelin molecules attach to locations on the pituitary known as Growth Hormone Secretagogue Receptors.

  • Healthy Sleep By reaching the deepest phases of sleep, the brain is encouraged to release increased levels of HGH.

  • Peptide Hormones Certain Peptide Hormones have been shown to increase Human Growth Hormone Production, although these hormones can also affect other systems as well.

  • Dopamine and Clonadine These hormones encourage the Hypothalamus to release GH-RH

  • Propranolol and Arginine These two compounds inhibit the secretion of Somatostatins by the Hypothalamus.

  • Hypoglycemia Low Blood Sugar Inhibits Somatostatin Secretion.

  • Vitamin B3 This vital nutrient is one of the key ingredients which stimulate Natural Growth Hormone Release.

  • Fasting Because the body increases HGH production as a result of lower blood sugar and increased hunger, fasting encourages the body to release enhanced Levels of Growth hormone.

  • Vigorous Physical Activity The body releases spikes of HGH to feed the muscles and cardiovascular system in order to encourage the body to function at a higher level.

List of Biological HGH Inhibitors:

  • Somatostatin Somatostatin is released by the Hypothalamus in order to decrease HGH Production. Some theorize that the Hypothalamus begins to produce too much Somatostatin later in life, contributing to Lower Levels of HGH Production with Age.

  • Growth Hormone and Insulin-like Growth Factor-1 The Hypothalamus increases Somatostatin production when stimulated by HGH and IGF-1 as a form of negative feedback mechanism.

  • Dihydrotestosterone Although Testosterone increases HGH production, Dihydrotestosterone inhibits Growth Hormone Secretion.

  • Glucocorticoids The conversion of Cortisone to Cortisol inhibits the function of Human Growth Hormone. The reverse is also true.

  • Hyperglycemia High levels of Insulin production counteract Human Growth Hormone Function.

  • Certain Medications Many non-biological medicines have an inhibitory effect upon HGH Production for various reasons.

Function of Human Growth Hormone

Human Growth Hormone belongs to a large group of hormones known as Anabolic Hormones. Although HGH is not a steroid like Testosterone or Aldosterone, it still produces a stimulative effect upon systems throughout the body.

Like most peptide hormones, Human Growth Hormone flows through the body, stimulating target receptors located on the outer barrier of cell structures. The most widely recognized function of Human Growth Hormone is to stimulate the growth spurt associated with puberty.

HGH and Height

There are two ways in which it seems that HGH affects height:

First, Peptide Hormones are fat-insoluble. This means that these hormones cannot break through cellular membranes. Because of this, Human Growth Hormone must attach to receptor sites on cell walls. HGH attaches to cartilages cells, encouraging the reproduction and division of chondrocyte cells. This causes the bones to grow longer.

The second pathway in which Human Growth Hormone stimulates height is through the creation of IGF-1 via the liver. Most Human Growth Hormone circulates through the body directly to the liver, where it is converted into IGF-1 and other Growth Factors. IGF-1 encourages the growth and enhanced cell-division of tissues throughout the body, also encouraging changes in height as a result of puberty. IGF-1 encourages organs in the bones known as Osteoblasts to manufacture bone tissue, which directly leads to changes in bone structure. IGF-1 also stimulates chondrocyte activity in a manner similar to HGH.

Why does Human Growth Hormone Increase Height?

HGH is able to cause an adolescent to grow in height because the ends of the bones are still largely made of cartilage. At the end of puberty, growth plates close, preventing the bones from increasing in length. When these plates, also known as Epiphyseal Plates, close, it signals the brain to produce less Human Growth Hormone, leading to the levels that we experience during our late teens and early twenties.

Importance of HGH After Puberty

After puberty, IGF-1 and HGH are responsible for a number of different health functions, including:

  • Increasing Body Fat Metabolism Human Growth Hormone speeds up the rate at which the body burns fat.

  • Optimizing Bone Mineral Density HGH encourages the healthy maintenance of the bones.

  • Stimulating Increased Muscle Mass - Human Growth Hormone encourages the muscles to remain stronger and prevent muscle atrophy.

  • Slowing Down the Rate at which the Body Absorbs Sugar Human Growth Hormone and Insulin work together to regulate blood sugar.

  • Encouraging the Healthy Function of the Pancreas

  • Contributing to Hormone Homeostasis Human Growth Hormone belongs to the Hyothalmic-Pituitary Axis. All of these hormones are intricately connected with one another, and optimal Human Growth Hormone function encourages the body to produce normalized levels of other hormones as well.

  • Strengthening the Immune System Human Growth Hormone encourages white blood cells and other tools of the immune system to replicate more effectively, encouraging fortified immune health.

Human Growth Hormone for HGH Deficiency

It should be clear at this point that Human Growth Hormone Production is vital to optimal health throughout the lifespan. Although the body normally becomes more sensitive to Human Growth Hormone Production with age, the body still inevitably reaches a point at which it does not produce enough HGH to support the healthy function of the body.

For many individuals, Human Growth Hormone Replacement Therapy is a viable option to encourage optimal function deeper into the lifespan. If you feel that you may be a candidate for Human Growth Hormone Replacement Therapy, talk to your doctor.


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Does Growth Hormone Have Anti-Aging Properties?

It is quite true that we are all going to get old. As a matter of fact, the generation of baby boomers is quickly approaching their mid-fifties, and the number of elderly people in America will continue to increase for another generation. Why then, do we have to resign to growing old in the same way that previous generations were forced to in the ages before us? Must we be weak, frail, fatigued, depressed? Living in fear to take a walk in the park for fear that we may fall?

It is a truism that youth is wasted on those who are young. If such a saying is true, why should the opposite statement also be true? Why must wealth and experience be wasted upon those that are old? Should not older men and women be able to retain their enthusiasm and energy in a grand effort to enjoy their autumn years?

We do not have to take age lying down! We here at the Conscious Evolution Medical Institute have learned that old age is largely a state of mind that has been induced by hormonal deficiencies. It is a state in which the hormones we so enjoyed in our youth have become less bountiful. It makes logical sense that with hrt hormone replacement therapy many of these symptoms can be alleviated or reversed.

One of the most impressive hormones that can be regained through Bio identical Hormone Replacement therapy is Human Growth Hormone. It can allow an older woman or gentleman to live a healthier, longer, and more active life. The greatest point to be made about Human Growth Hormone is that it truly is not all that fantastic of a concept. Growth Hormone is naturally produced by the body, and it is produced in large quantities when we are in our youth. The longer we can retain Growth Hormone, the more we can slow down many of the devastating effects of aging.

It makes perfect sense. Growth Hormone is vital to growth processes within the body. GH supplement is provided to young children who are maligned with slow skeletal growth, and it allows them to grow taller than they would without treatment. The problem is that Human Growth Hormone levels drop at a steady rate in all men and women after they enter adulthood. After decades of research, we now know that Human Growth Hormone provides significant benefits throughout the lifespan. For this reason, we must conclude that Growth Hormone is vital for the maintenance and rejuvenation of the body in adulthood. Research regarding the effect of Growth HRT upon elderly patients provides evidence that the main role of the hormone in adulthood is to allow one to live a longer, healthier life of higher quality.

Where does Human Growth Hormone Originate?

Human Growth Hormone is produced in the anterior area of the pituitary gland which is buried deep within the brain. Human Growth Homrone is a microscopic protein molecule. It has chemical similarities with insulin, though HGH is secreted in brief, sharp pulses after a person exercises or in the initial hours of rest. Human Growth Hormone only stays in the blood stream for a few minutes. For this reason, it in incredibly difficult to measure Human Growth Hormone in serum. Though it does not remain in the blood stream for long, HGH binds to the liver which turns some of the hormone into Somatomedin-C, which is also known well by the name Insulin-Like Growth Factor I (IGF-1) Since IGF-I stays in the blood for up to one and a half days, a blood sample that contains IGF-I proves that HGH is being produced. Normal IGF-I levels in the blood tend to appear in volumes of 200 to 450 ng/ml. However, one third of men and women that are over the age of fifty display levels of HGH that are lower than 200 ng/ml. During puberty, Human Growth Hormone levels are at their peak and IGF-I reaches levels of 600-800 ng/ml or even higher. In normal women and men under the age of forty, less than five percent have levels of HGH that are below 250 ng/ml! After the age of 40 many women and men have a level of Human Growth Hormone that is similar to that of an octogenarian! Human Growth Hormone may be the means by which we can age gracefully.

When IGF-I levels drop under the baseline adult range, energy levels and bone and muscle strength tend to decrease as well. Cell regrowth, tissue repair, vital organ repair, general rejuvenative ability, enzyme production, and hair, skin, and nail revitalization will begin to occur less effectively

Though decreased levels of Human Growth Hormone and increased age are certainly directly correlated, those who lose full function of the pituitary gland, whether through accident, infection, or surgery, will immediately begin to be maligned with acute ill effects.

It is vital to understand that natural HGH will inevitably decline with age!

In those who are utterly lacking a functional pituitary, body composition changes and a shift occurs where the amount of fat increases by 7-25%. Lean mass of the body decreases at a similar rate. Mass and strength of the muscles diminish as well. Studies in regard to bone density show that in those patients with no pituitary input, it seems as though an individual ages by around 15 years by analysis of the density of both the long bones and the spinal bones. As Human Growth Hormone flags, weight increases of as much as fifty pounds occur. Beyond this, there are issues regarding cholesterol as well. Levels of triglycerides go up, and good HDL cholesterol suffers. Cardiovascular complications occur more often, which could be related to the thickening of the vascular walls of the heart. Decreased output by the heart leads to further problems.

Hormonal insufficiencies such as these often lead to people such as these to report a serious decline in their capacity to exercise, and they often suffer from cardiovascular disease, which leads to early mortality. Also, they report issues with loneliness, depression, focus, and fatigue. In general, they just suffer from a general lack of well-being.

Hope on the Horizon: Food and Drug Administration approves Human Growth Hormone for Use by Adults

Recombinant HGH has recently gained approval by the FDA for women and men of adulthood for the therapy of Growth Hormone Deficiency and hypopituitarism. If a person suffers from hypopituitarism, Human Growth Hormone therapy is compatible under the majority of insurance policies. After being approved for therapy, patients are administered Human Growth Hormone treatment and testing under professional supervision. Our experience and the revelations of research provide ample evidence that Human Growth Hormone Replacement Therapy offers benefits to those that have insufficient levels of Growth Hormone. This deficiency is often referred to as Somatotropin Deficiency Syndrome. The Conscious Evolution Medical Institute also provides Human Growth Hormone treatment for patients who suffer from Somatomedin-C (Insulin-Like Growth Factor-1) levels under 200 ng/ml that are approved in our Internal Review Board registry, but these patients are required to pay for their treatment.

Please realize that by undergoing a global hormone replacement regimen, administering progesterone, estrogen, testosterone, thyroid, pregnenolone, or DHEA (other vital hormones which a patient may be co-deficient) when necessary in addition to Human Growth Hormone, one can minimize the costs, side-effects, and dosage of treatment.

Growth Hormone Replacement Therapy Changes

Administration of Human Growth Hormone often leads to substantial changes in the composition of the body: lean muscle mass increases as fat mass percentage is reduced. Using Human Growth Hormone at the modest dosage of 0.003 mg/kg over the course of six months was shown to improve lean muscle mass in 24 patients that had a Human Growth Hormone deficiency (1). Improvements in lean muscle mass have been associated with higher levels of protein synthesis, along with muscle function and mass. The percentage of body fat also drops after six months of Human Growth Hormone administration. The most fat is eliminated from the areas of the trunk and the stomach, rather than the legs, neck, and arms. This fact is evidence that Human Growth Hormone replacement treatment can reverse excess stomach fat associated with Human Growth Hormone deficiency, along with reducing risks of heart problems.

Heart Health and Metabolism of Cholesterols

Human Growth Hormone Therapy for adults also shows is believed to have a positive effect upon cholesterol. In new research, it has been shown that brief regimens of Human Growth Hormone Therapy led to reduced LDL (or bad) cholesterol (7) while also boosting heart function and capacity for exercise. Participants showed higher levels of oxygen intake as well as strength during cycling exercise. Human Growth Hormone has been associated with higher levels of muscle mass and stronger and longer action upon the treadmill (8). Recent research by Fazio has shown that those who have experienced heart failure have shown improvement after being given high dosage of Human Growth Hormone Therapy.

Bone Density

Among the most stunning effects of Human Growth Hormone is its effect upon the skeletal system, muscles, and tissues. It provides a significant level of rejuvenation to these systems. Skin health improves, damaged bones heal more effectively, and significant levels of improved muscular strength have been reported during Human Growth Hormone Therapy. Others have reported that signs of aging are fading from their skin. Sometimes hair regrowth occurs in male hormone replacement therapy patients as well as female patients. These changes provide evidence that testosterone, DHEA, and Human Growth Hormone are anabolic (synthesizing) hormones that significantly rehabilitate tissue of the body. Unfortunately, as we age, catabolic processes lead to faster levels of tissue breakdown. Human Growth Hormone combats the catabolic processes of aging.

The most significant way that Human Growth Hormone effects the skeletal system is through its role in enhancing the body's ability to build and repair the bones. Human Growth Hormone stimulates the proliferation of fibroblast (ligament) and osteoblast (bone) cells in the skeletal system. In recent clinical research using the powerful techniques of single photon absorptiometry and quantitative tomography, marked increases of 4% and 5% were shown in cortical and spinal bone density over the course of twelve months of therapy in adults deficient in Human Growth Hormone (4). In conclusion, it seems that the administration of Human Growth Hormone may lead to an enhancement of multiple organ systems of the body through the positive effect it has upon the skeletal system.

More examples of Human Growth Hormone's anabolic effects include muscle gain and increased appetite, increased capacity for exercise, increased capacity of the lungs, and increased would rehabilitation. Many also report that liver spots, also known as senile keratoses, begin to fade after eight weeks of Human Growth Hormone Therapy.

Side-Effects of Low Dosage Human Growth Identical Hormone Replacement Therapy.

Human Growth Hormone dosage is a vital consideration in those who suffer from Human Growth Hormone Deficiency. Overdosage of Human Growth hormone is associated wit many signs of excess Human Growth Hormone. Among these symptoms are hypertension, carpal tunnel, and excess fluid retention. However, by using more modest doses of Human Growth Hormone, it was demonstrated by Bengtsson that only mild side-effects such as slight joint pain and mold fluid retention occur. Only a single case of carpal tunnel was discovered. In each of these cases, further restriction of the Human Growth Hormone dose lead to full elimination of the side-effects. Another clinical study only used a small dose of 0.01 mg/kg, which was injected three times each week. In this study, there were zero side-effects reported (8). Many studies provide evidence that says that low dosage Human Growth Identical Hormone replacement therapy generally only causes modest side-effects, if any.

Benefits of Hormone Replacement Therapy with HGH.

Improve Body Composition: Boost muscle mass and reduce fat for a shift in body composition of as much as 20 pounds. This change can lead to higher sex drive, as well as enhanced physical well-being and self perception.

Improve Energy: Human Growth Hormone patients report higher levels of energy without the need for afternoon snacks, stimulants, caffeine, or cigarettes. This energy boost helps them become more confident in their self control and enhances their capacity for exercise.

Improve Focus: An intriguing yet untested potential benefit of Human Growth Hormone is a return of mental focus and enhancement of memory. Since Human Growth Hormone provides improvement to the intracellular and vascular systems which support the cells, it is not at all surprising that these benefits have been reported in individuals.

The Future

Many fundamental questions remain regarding the exact medical definition and preferred treatment for partial versus total Human Growth Hormone Deficiency. Also, it is not clear whether all of the realized positive effect of full Human Growth Hormone Replacement Therapy will occur in those that undergo low dosage or combination treatments. Even so, is has already been made clear that even small doses that do not result in potential side-effects sufficient level may be sufficient for some to reach their metabolic goals. We here at the Conscious Evolution Medical Institute hope that our continued clinical evaluations will help lead to more efficient usage of Human Growth Hormone, as well as help reveal more of this wondrous therapy's benefits while eliminating incidence of increased cardiovascular and general morbidity.

Works Cited

Cuneo, Salomon, and Hesp, et al. Treatment effects of Recombinant HGH upon Metabolism and Body Composition among Adults with Growth Hormone Deficiency. New England Journal of Medicine 1989; Issue 321: Pages 1797-03.

Bengtsson. Consequences of Growth Hormone Deficiency in Adults. Acta Endocrinoligica 1993; Volume 128: Pages 2-5.

Cuneo, Salomon, Wiles et al. Effects of Human Growth Hormone Treatment Among Adults Whom are Deficient. Applied Physiology Journal 1991; Volume 70: Pages 695-700.

Halloran, Tsatsoulis, Whitehouse et al. Increased Bone Density after Human Growth Hormone Therapy Upon Deficient Adults. Journal of Clinical Endocrine Metabolism 1993;Volume 76: Pages1344-48.

McGauley, Cuneo, Salomon et al. Psych. Self-perception changes due to Growth Hormone Treatment in Adults with Human Growth Hormone Deficiency. Hormone Research 1990; Volume 33(Supplement 4): Pages 52-54.

Bengtsson, Eden, Lonn et al. Therapy of Adults with Human Growth Hormone Deficiency with Recombinant Growth Hormone therapy. Journal of Clinical Endocrine Metabolism 1993;Volume 76:Pages 309-17.

Johnston, Bengtsson. Effects of Growth Hormone and its Deficiency upon Heart and Lipids. Acta Endocrinologica 1993;Volume 128(Supplement 2):Pages 69-70.

Amato, Carella, Fazio et al. Heart Structure, Metabolism of Bone, and Body Composition Heart Structure in Growth Hormone-Deficient Adults Effects of Human Growth Hormone Replacement Therapy at Mild Dosage. Journal of Clinical Endocrinology and Metabolism. 1993;Volume 77:Pages1671-76.

Fazio, Sabatini, Capaldo, et.al. Test study of GH in the treatment of cardiomyopathy. New England Journal of Medicine. 1996;Volume 334:Pages 809-14.

The above information does not provide sufficient evidence to self-diagnose a particular procedure or treatment. It should not lead one to believe that this is the only treatment option available.


Exercise to Increase your HGH Production!


Written by Dr. Welsh, Published on 03 October 2015

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Five Ways that Exercise Slows Down Aging

So, we all know that Exercise is an effective way to keep the body healthy and in peak condition, but did you know that exercise can also slow down the aging process as well?

In this article we will discuss five ways that engaging in routine physical exercise can rejuvenate your body and slow down the decline associated with growing old.

Exercise Stimulates the Production of Human Growth Hormone

Human Growth Hormone is one of the most important biological molecules that the human body produces. Human Growth Hormone has the capability to now only prevent you from looking older than your age, but it improves the way that your body feels as well. Human Growth Hormone Deficiency is correlated with a number of different problems related to growing old.

How does exercise raise Human Growth Hormone Levels?

HGH levels are sustained through two distinct periods of the human daily cycle. The first period that Human Growth Hormone production occurs is during sleep. HGH plays a vital role in restoring the body after a long day, and while we are in the deepest phase of sleep, the body releases Human Growth Hormone from the pituitary in order to mend the minor breakdowns caused by general wear and tear that accumulates because of the wages of the day.

HGH Levels Boost after Exercise

The second period of time where HGH production occurs at a high rate is during and after exercise. Human Growth Hormone is one of the key factors which help sustain us during exercise and help our bodies recover and enhance as a result of physical activity. Human Growth Hormone breaks down unhealthy fat deposits across the body. It displaces that fat and converts it into energy that the body can use during exercise to enhance endurance and allow us to run, fight, and play harder.

How does HGH Increase Muscle Mass?

Although Human Growth Hormone is stimulated by engaging in exercise, it also plays a major role in making exercise more fruitful. After physical activity is completed, Human Growth Hormone is an important factor in muscle growth as well. HGH sends energy and nutrition directly to the muscle cells which use the tools provided to them by the molecule in order to make the muscles bigger and stronger as a result.

If you dont engage in sufficient exercise in your weekly routine, then your body will not receive the amount of Human Growth Hormone that you need to maintain your health, causing you to age more quickly. A sedentary lifestyle is highly correlated with cardiovascular conditions such as heart disease, and a lack of exercise leads to further buildup of fat which contributes to obesity.

Exercise Tones the Body and Helps you Remain Youthful

Strengthen Muscles

Engaging in vigorous and regular exercise does wonders for the body. The ideal aesthetic figure is dependent upon regular maintenance through proper diet and exercise. Stronger muscles prevent you from becoming overly flabby. The place where this is the most obvious is in flabby arms. Flabby arms are the direct result of a combination of unwanted fat and weak muscles in the bicep and triceps which cause skin and tissue to just kind of hang from the arm.

Reinforce the Joints

In addition to this, regular exercise is incredibly important for joint health as well. Engaging in routine exercise can help slow down or prevent arthritis and carpal tunnel syndrome. Be careful not to overwork the joints with excess weight, however, because prolonged and repeated exposure to intense pressure can also lead to joint issues. The ideal is to find a point at which you are putting a significant amount of stress on your muscles and joints without overworking your body.

Change your Dietary Habits.

Also, your body will look more toned if you combine proper nutrition with exercise, and you will shed pounds as a result. The problem that some people have is that they work out, but they still overeat and consume too many fatty foods. Although their muscles are getting stronger, the results are significantly less defined because their tone is covered up by gobs of fat. It is possible to even hide a nice six pack or nicely toned stomach under all of that fat. Losing body fat and increasing muscle tone helps eliminate sagging skin on the face and neck as well, giving your profile a much younger look. Lack of exercise can wreak havoc on overall physical appearance.

Boost Metabolism!

Exercise is pivotal in maintaining a healthy metabolism. Physical activity kick-starts your body, and your brain sends signals throughout the body to release energy stores from fat as well as food that you consume throughout the day. This energy travels straight to your muscles where it is converted from calories to healthy muscle. In addition to this, your body gives off heat energy and your heart beats more rapidly. Your body consumes more calories, and as a result you lose weight. This increased metabolism occurs even when you are no longer exercising. With enough regular activity, the body begins to burn more baseline calories throughout the day, meaning that daily exercise contributes to weight loss 24 hours a day.

Reduced metabolism is associated with a number of different physiological problems. Slower metabolism means more fat. If you arent exercising, your body is converting most of the calories that you consume directly into the body in the form of adipose fat. Also, reduced metabolism leads to feelings of fatigue and exhaustion, because if you dont maintain a strong metabolism, your body wont have the energy that it needs in order to even go through the motions of the most sedentary of days. The workday will seem longer and longer, and focus and attention will break down as a result, preventing you from performing at your best on the job.

Exercise Prevents Numerous Diseases

Its never too late to begin a more active lifestyle, but perpetual abuse of your own body can result in irreversible damage. Long term sedentary lifestyle and obesity directly lead to stage-two adult diabetes, which is one of the most dangerous chronic illnesses that afflict men and women in America today. All that it takes to prevent this devastating illness is a bit of exercise and dietary restraint.

The benefits provided by the preventative medicine known as exercise are tangible in the form of scientific study as well. In a recent study, researchers took blood samples from individuals who came from two groups. All factors otherwise remaining equal, men and women who exercise regularly have DNA which appears an average of nine years younger than their counterparts who engaged in a sedentary lifestyle. Exercise truly is a hallmark of longevity medicine.

Exercise Improves Overall Health

Engaging in exercise improves health in nearly every possible way. Study after study has shown that those who engage in regular exercise are healthier than those who do not. Exercise strengthens the immune system, helping you fight off illness and maintain your overall health. The feelings of exhaustion and tiredness do not merely affect your endurance but the effectiveness of your other organ systems as well. If your body is not physically prepared for day to day wear and tear, your immune system suffers as a result. If you are routinely exhausted even with little to no physical activity, then your immune system will be less capable to ward off disease.

Also, as was mentioned before, decreased metabolism means that your circulatory system will have more problems as well. When you dont exercise regularly, your baseline heart rate starts to increase as a result. Regular cardiovascular exercise makes your heart do more with less work. The heart is a muscle just like any other in the body, and if you dont give it the proper attention, then it wont be able to serve you. This fact becomes more and more true with age.

There are numerous studies that show that in addition to helping you feel younger, exercise literally adds years to your life, even if you decide to change your lifestyle later in adulthood. Recent longitudinal research has shown that men and women over the age of fifty who engage in light physical activity live an average of 1.1 years longer than their sedentary counterparts. If you exercise more regularly, the results will be even more astounding. If you remain very active after the age of fifty studies have shown that you will live an average of 3.2 more years than a sedentary man or woman.

Exercise Boosts Energy Levels

We all know that initiating a workout regimen can be hard. The initial couple of weeks can be very strenuous and make you feel weak and exhausted. These feelings are only temporary, but they are one of the biggest roadblocks to maintaining a healthy and active workout regimen. It helps to start relatively slow, working your body to a point of strain, but not to overwhelming exhaustion. Over time, your muscles and your cardiovascular system will acclimate to the change in your activity level and you will experience intensely increased levels of energy and endurance as a result. At first, you may only jog a quarter mile before having to slow down and catch your breath, but eventually and with enough effort, you will be able to run for miles. Its all about sticking to the program and working toward slowly but ever-increasing goals. You will notice that as your ability to endure strenuous physical activity increases, so will your ability to make it through the day without faltering. Exercise is all about priming your body for everything the day has to throw at you without going through a draught of energy because of your lack of training. There are dozens of studies which directly link increased exercise and physical exertion with overall increased endurance when it comes to everyday life.

Exercise for Energy, Sleep, and Memory

People who exercise regularly also sleep better, and this is the result of both increased metabolism and normalized hormone production. Engaging in an active lifestyle helps people maintain a good routine for their daily life. Waking up every morning to engage in healthy exercise primes you for waking up early and then boosts your metabolism throughout the day. Even when you engage in exercise later in the day, it helps spur proper hormone production which helps you sleep more soundly as a result. Good sleep enhances exercise as well in a positive feedback loop. Your body repairs and rebuilds itself during sleep, and when you sleep properly, you build muscle more effectively.

Exercise improves all aspects of cognitive ability as well. The combination of increased endurance and increased blood flow increases ones ability to think clearly and make good decisions. Also, you will be able to retain and recover memories more fully. Having the energy to pay attention helps you retain information that you gather during the day. In addition to the boon provided by exercise in regard to memory, your better sleeping habits will help your memory become stronger as well, because it is during the night that the information you learn through the day gets converted into permanent knowledge.

The cognitive benefits of healthy exercise habits outweigh even those provided by stimulants such as caffeine and sugar. If you need to study for an exam or maintain sharp focus at work every day, you will benefit greatly from a regular exercise routine. With enough dedication it may even help you kick the habit of caffeine altogether as your exercise assumes the role that stimulants once played in your life.

Exercise Reduces Stress

When a person lives by a sedentary lifestyle, stress begins to pile up inside them and can make life less enjoyable as a result. Everyone has heard the term blowing off steam related with exercise, and it is completely true. Burning calories with exercise helps people take their minds off difficult things in their lives and is an incredible and safe form of escape. In addition to this, the physical and mental systems of the body are intricately connected, so releasing pent up physical energy relieves stored mental energy as well, helping a person maintain a clear mind which is not plagued with troubles.

Pick your Own Exercise Routine

One of the keys to reducing stress by means of exercise is to decide which forms of exercise appeal to you. Although working out is supposed to be hard, theres no reason it cant be fun. Bring an IPod with you to the gym so you can zone out to your favorite music. Get engaged with your competitive nature by playing basketball or soccer instead of just running alone. Bring a close friend to motivate you and help the time pass more quickly. Catering exercise to your own interests will help you live a stress-free life in which it is easier to enjoy your newfound physical appearance and mental demeanor.

Exercise Releases Dopamine and Endorphins

The act of exercise also leads directly to the release of both dopamine and endorphins. Endorphins account for the rush that you feel when you engage in exercise or achieve success. Endorphins act as natural physiological relaxers which help you feel energized.

Dopamine can be best described as the bodys pleasure chemical. Engaging in strenuous physical exercise or exertion leads to the release of dopamine. This is your brain literally rewarding you for all the hard work that you are doing for its benefit. Also, if you exercise regularly, you will actually feel compelled to exercise in order to achieve the rush of dopamine that exercise provides. Your brain knows that exercise is good for you in spite of the temporary pains that can result from exertion, so it produces positive signals to encourage you to continue the habit. The problem is, if you become too out of practice, the negative stimuli of exertion and ill-preparedness will work against you and hinder your ability to adhere to an exercise plan.

Although we normally attribute stress to a mental condition, stress can affect all organ systems of the body. High levels of stress reduce immune sufficiency and make us more prone to illness.

Stress Makes it Hard to Cope

Stress reduces our mental ability to cope with the issues that crop up regularly in day to day life. Stress hinders bone health and leads to the atrophy of the muscles, because the body becomes more concerned with core processes than the everyday functions that keep us optimally healthy. Long term stress creates immense levels of fatigue which prevent us from really getting anything out of our shorter and shorter days. High stress makes good sleep nearly impossible to attain. The great thing is that exercise relieves stress in a natural way that no medicine or other method can. In cases of extreme anxiety and stress, a mixture of medication and exercise is commonly quoted as the best method of ensuring that stress levels begin to subside.

Stress, Cortisol, and Aging

Also, stress plays a big role in the aging process. Stress is correlated with increased levels of cortisol in the blood stream. Cortisol is a natural response to pain or negative physiological triggers such as hunger. It plays an important role in proper human function, our ability to withstand pain, and our ability to maintain a normal circadian rhythm. Cortisol is actually what wakes us up in the morning most efficiently. The body starts to become hungry, and the body also recognizes that it has achieved an optimal level of rest, so cortisol levels slowly increase in order to naturally wake us up in the morning.

When cortisol levels are too high in the body, it disrupts many physiological processes. It becomes harder to be well rested and sleep through the night because cortisol levels spike at inopportune times. Also, cortisol levels eat at the bodys ability to produce healthy levels of testosterone, and when cortisol levels remain too high over an extended period of time, the muscles start to atrophy and the skin begins to sag, wrinkle, and loosen. High levels of cortisol also lead to elevated levels of estrogen derivatives in the male bloodstream which cause the body to store fat at an accelerated pace. Long term sedentary habits and high stress speed up the male aging process and lead directly to emasculation.

And think, the easiest way to avoid this is through regular exercise! Cortisol levels stay low, higher levels of Testosterone and Human Growth Hormone dominate hormone balance, and the body melts fat and builds muscle, improving physical appearance and mental aptitude. This causes you to both look and feel younger than you actually are, allowing you to make the most of your life.

The Conscious Evolution Institute

We at CEI believe that Exercise is an important component to any Hormone Replacement Program. The above information benefits both those who suffer from Hormone Deficiency and those who simply want to improve their lives for the better. Youll notice that many of the benefits provided by Human Growth Hormone and Testosterone are also provided by exercise.

When used in tandem, exercise, proper nutrition, and Hormone Replacement Therapy are an amazing three part plan to looking and feeling ten, fifteen, or even twenty years younger!

Testosterone and Human Growth Hormone Kickstarters

Hormone Replacement Therapy works as a kind of kickstarter for those who have lived a sedentary life for too long and are having trouble getting into a routine workout plan. HGH Hormone Replacement Therapy helps burn fat and provides enhanced energy levels which make it easier to both start and stick with a workout plan. Both Testosterone and Human Growth HRT also amplify the benefits of exercise. HGH helps you lose weight while also funneling energy to your muscles while you are at rest in order to enhance the effects of your anaerobic or cardiovascular workout plan.

Testosterone and Bodybuilding

Testosterone is a building block of strong muscles and masculine physique. Testosterone acts as a sort of muscle booster which encourages your muscles to respond more actively to physical activity. This is why men have more developed muscles than their feminine counterpart, and why those who abuse Testosterone often have super-human muscle tone in comparison to those who have normal Testosterone levels.

Avoid Testosterone Abuse and HGH Abuse

Although we certainly dont encourage the abuse of either Testosterone or Human Growth Hormone, Testosterone and HGH Deficiency also lead to the opposite problem. The male body is not able to maintain the optimal manly physique without proper levels of these vital hormones.

HGH, Testosterone, and Exercise

Although exercise does encourage the enhanced production of Human Growth Hormone, as men age, the bodys capacity to produce its own HGH and Testosterone start to decline, and the positive benefits of exercise decrease as a result. In addition to this, it becomes harder to get motivated to exercise and the body starts to decline at a faster pace even with a proactive preventative exercise regimen.

How much should I exercise in order to maximize my health and the benefits of Hormone Replacement Therapy?

We recommend that you engage in cardiovascular exercise at least four times a week in order to benefit at an enhanced rate from HGH and Testosterone Hormone Replacement Therapy. You should plan to run or engage in a similarly vigorous cardiovascular activity for at least thirty minutes. These benefits also continue to build if you decide to exercise seven days a week. In addition to this, you should also engage in weight training as well.

Again, you should lift weights at least four times a week, preferably every other day. Alternate between upper and lower body workouts every session. Over time, your body should acclimate to this physical stress and if you really enjoy working out you can start working out daily, with a recommended rest period of at least one day per week. You should still alternate between upper body and lower body weight training in order to give your body time to recover and rebuild itself. It is important to realize that rest plays a vital role in a proper weightlifting routine.

The muscles strengthen most during the period of rest between workouts, so working out the same muscles every day overstresses them and reduces the benefits provided by your workout. Alternating muscle groups allows you to maximize the effects of your workout by working out every day or every other day while also giving your muscles time to rest.

Cardiovascular exercise is not affected in quite the same way by muscle fatigue, because since you are not putting as intense pressure on your muscles, they need less time to recover. Cardiovascular exercise encourages general muscle tone rather than muscle growth, and provides significant cardiovascular benefits that simple weight lifting cant achieve. This is why its important to combine both forms of exercise in order to maximize the benefits.

Conscious Evolution Institute for Human Growth Hormone and Testosterone

The Conscious Evolution Institute is your best source for Human Growth Hormone Replacement Therapy and Testosterone Replacement Therapy, as well as other hormone and supplemental treatments which can enhance both your life and your workout. We provide Hormone Therapies for patients that display a legitimate Hormone Deficiency in order to help them live longer and fuller lives.

When do Testosterone and HGH Hormone Levels Decline?

Testosterone and HGH levels start to decline around the age of thirties and they decrease at a steady rate across the lifespan. Even though from year to year this may seem negligible, over time the changes can be staggering. Although Testosterone and HGH HRT provide significant physical gains when used as a treatment for Hormone Deficiency, we do not provide Hormone Treatments simply for performance enhancement. It is illegal in the United States to prescribe Testosterone Creams or Human Growth Hormone Shots simply for that purpose.

What are the Symptoms of Hormone Deficiency, Hypogonadism, and Hypopituitarism?

Below are some of the general symptoms of Hormone Deficiency:

  • Muscle weakness and fatigue

  • Development of adipose fat around the waist, stomach, and thighs

  • Fuzzy memory and cognitive decline

  • Trouble sleeping through the night

  • Frequent illness because of a suppressed immune system

  • Sexual dysfunction (an inability to perform optimally in the bedroom)

  • Low or nonexistent libido (Lack of sexual interest)

  • Increased anxiety or depression with no underlying cause

If you are experiencing more than two of these symptoms and you are over the age of thirty, there is a significant chance that you are suffering from the effects of Hormone Deficiency, whether it be as a result of HGH Decline, Testosterone Decline, or a combination of both.

The Conscious Evolution InstituteYour Best Source for Legal Hormone Replacement

If you are concerned with your Hormone Balance, we encourage you to contact the Conscious Evolution Institute today. We have a fully trained and board-certified staff of specialists and physicians who provide Anti-Aging and Longevity Treatments for patients just like you. Hormone Replacement Therapy, in combination with proper nutrition and exercise, is a life-changing therapy that can restore your youth and vitality while adding on good years to the end of your life.

Dont wallow in your slow decline when there is a simple and effective way to reverse and alleviate the effects of aging. Hormone Replacement Therapy with HGH and Testosterone has helped hundreds of thousands, if not millions, all across the globe. We encourage you to call us today. There is no obligation and our well-educated staff can answer any questions you may have about our services or other vital information regarding Hormone Replacement Therapy.

Explore HGH.tv for more information about life-changing Hormone Replacement Therapy.

Source: http://www.bestsyndication.com


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If your doctor only prescribes testosterone by itself, you will probably have a rough ride. The tendency is for you to feel great the first couple months, while you increase testosterone levels, followed by a slow deterioration, once your estrogen creeps up.

High estrogen negates a lot of the positives from testosterone therapy, resulting in the same symptoms of low testosterone you had in the first place!

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