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Introduction to Human Growth Hormone


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How does Human Growth Hormone Work?

Human Growth Hormone is one of the most important metabolic hormones secreted by the human body. The hormone itself goes by a few different names. Somatotropin refers to naturally occurring Growth Hormone that is present in all animal species. Somatotropin also refers to medically derived HGH that has been gathered from the pituitary gland of cadavers. At first, this was the only way to utilize HGH for medical use.

Today, however, almost all medical Human Growth Hormone is synthetically derived via a process known as Recombinant DNA Technology. Although the process is synthetic, the Human Growth Hormone created from the process is functionally and biologically identical to the Growth Hormone that your own Pituitary secretes.

HGH derived from Recombinant DNA Technology is also referred to as Somatropin. Another, more commonly used term used to describe Recombinant HGH is Bio-Identical HGH. This term both signifies the different origin of this form of HGH while also recognizing that the hormone created in the laboratory is completely identical to that which is naturally created by the body.

Why do they have different names if they are the same thing?

There are a couple of important reasons. First, there are risks involved with Human Growth Hormone derived from cadavers that are not at play when utilizing Bio-Identical Human Growth Hormone, the most significant of which is Krutzfield-Jacobs Disease. Krutzfield-Jacobs Disease is prion disorder that shares some similarity with Alzheimer's disease. In rare cases, HGH that was harvested from cadavers was tainted with traces of this debilitating disease.

Given the severity of the disease, the use of Harvested HGH for Medical Usage completely ground to a halt, and new techniques to safely create Bio-Identical Human Growth Hormone were invented in order to fill the void. Today, all Hormone Replacement Therapy is conducted using Bio-Identical HGH, so most people do not differentiate between the two forms in everyday speech.

The second reason that the two forms of hormone are named differently is because source also matters for legal reasons. Different companies have legal rights to particular forms of Human Growth Hormone. No company has a legal right to natural Human Growth Hormone, but companies have patents which protect the specific medical techniques that they use in order to synthesize HGH for medical use.

A few of the most common forms of HGH Hormone Replacement Therapy are Nutopin, Humatrope, Saizen, and Norditropin. Today, Human Growth Hormone is incredibly safe, and none of the pitfalls of early forms of HGH are at play any longer, allowing you to experience the pure effects of the treatment.

How is Human Growth Hormone Composed?

Human Growth Hormone is known as a Peptide Hormone. Peptide hormones are made up amino acids chained together by peptide bonds. There are over forty hormones secreted by the human body, and they all have unique and vital purposes in regard to the proper and optimal function of the body. The primary function of Human Growth Hormone is to encourage optimal cellular metabolism throughout the body.

HGH is also known as a mitogen for this reason. Mitogens are chemicals which encourage the the cells of the body to reproduce and divide at an increased rate. Although this sounds like something simple, it is actually incredibly complex. HGH affects every system in the body in a unique way. It makes the muscles grow larger, it strengthens and hardens the bones, and it keeps the immune system running at peak capacity.

Specifically, HGH is a poly-peptide hormone which is comprised of 191 amino acids linked in a specific configuration. Human Growth Hormone weighs 22,124 daltons. A dalton is a unit of molecular weight which is identical to the atomic mass of the molecule. This entire collection of amino acids is linked into one long chain. This chain forms four helix structures which are responsible for the proper function of the cell.

All animal species on the planet have Growth Hormone. Although all species need Growth Hormone to function, every animal has its own unique formulation. Because of these unique differences in structure, the only forms of Growth Hormone which stimulate the human brain are those of human beings themselves, and certain Old World Monkeys. No other form of Growth Hormone produces any affect on the human brain.

Endogenous Human Growth Hormone is produced only in the pituitary gland by tiny organs known as somatotrophs. The somatotrophs are responsible for the manufacture, storage, and release of these hormones. The somatotrophs are located on the outside wings of the pituitary.

There are two genes responsible for the secretion of HGH. These two genes are known as GH-1 and GH-2. The specific location of the Human Growth Hormone genes is on chromosome 17 in region q22-24. Although we have described the primary form of Human Growth Hormone above, the pituitary gland produces smaller amounts of slightly different formulations of HGH which seem to be correlated with specific outside stimuli. Researchers are just beginning to more fully understand the full function of these alternate versions of the HGH Molecule.

How is Human Growth Hormone Regulated?

HGH is primarily controlled by hormones delivered from the Hypothalamus. The region of the hypothalamus responsible for Human Growth Hormone Regulation is known as the Neurosecretory Nuclei. This structure produces a hormone known as Growth Hormone-Releasing Hormone, abbreviated GH-RH. GH-RH is also referred to in some scientific circles as Somatocrinin.

The Neurosecretory Nuclei also releases a hormone which inhibits the production of Human Growth Hormone known as Somatostatin. Somatostatin is also sometimes referred to as Growth Hormone-Inhibiting Hormone, abbreviated GH-IH. These hormones make their way from the Hypothalamus to the Pituitary Gland via a pathway known as the Hypophyseal Portal System. This structure is a series of small blood vessels which directly link the Hypothalamus to the Pituitary Gland.

A second hormone which has been shown to increase the production of Human Growth Hormone is Ghrelin, which is a hunger stimulator.

Although the release of Human Growth Hormone by the pituitary is mainly the result of the interplay of GH-RH and Somatostatin, the release of these hormones are influenced by a number of different outside circumstances.

Human Growth Hormone Stimulators

The following factors are HGH Stimulators:

Healthy Sleep Human Growth Hormone is primarily secreted during the deepest hours of sleep.

Proper Nutrition Healthy nutrition provides the body with all of the equipment that it needs to properly produce HGH. Improper nutrition forces the body to pick and choose which systems receive the limited nutrients available.

Physical Activity The human body secretes significant levels of Human Growth Hormone during vigorous physical activity.

Human Growth Hormone Inhibitors

The following factors are HGH Inhibitors:

  • Poor Sleep This prevents the body from receiving its largest full dosage of Human Growth Hormone each day.

  • Sedentary Lifestyle Without healthy exercise, the body does not produce as much Human Growth Hormone as it should.

  • Excess Fatty Acids High levels of Triglycerides and LDL cholesterol have been shown to decrease the body's ability to properly synthesize HGH.

  • Excess Insulin Production The more Insulin that you produce, the less HGH that your body will secrete.

  • Obesity Excess fat in general limits the body's ability to properly produce Human Growth Hormone.

  • Stress Abnormally high stress levels negatively impact HGH Secretion.

There are also some uncontrollable factors which can have an impact on Human Growth Hormone Production, including gender, heredity, and age.

How is Human Growth Hormone Released?

The Somatotrophs release Human Growth Hormone in pulses when stimulated by the Hypothalamus. The largest pulses of Human Growth Hormone Production occur around an hour after falling asleep. During this period, the body releases 13-72 nanograms/milliliter of HGH into the blood plasma. Aside from this large, primary release of Human Growth Hormone, HGH production is largely unique to the individual, and can also change significantly from day to day.

Almost half of Human Growth Hormone Secretion takes places during the 3rd and 4th stages of deep sleep. During waking hours, HGH secretion peaks every three to five hours. When these peaks occur, the window of HGH secretion can be as high as 45 nanograms/milliliter. Between these highs, base Human Growth Hormone remains very low, less than 5 nanograms/milliliter. It should be clear based off this data that poor sleeping habits can wreck a person's HGH Levels, negatively impacting their health in numerous ways.

HGH and Aging

Human Growth Hormone Production is distinctly correlated with the aging process. Human Growth Hormone is produced at its highest rates during the teenage growth spurt, peaking and lowering to a certain plateau at the end of puberty. During puberty, HGH secretion can reach levels as high as 700 micrograms per day. After puberty, adults normally secrete around 400 micrograms per day.

We continue to produce this healthy level of Adult HGH throughout our late teens and twenties. Beginning in the late twenties or early thirties, the pituitary gland starts to produce less and less Human Growth Hormone. The rate at which this decline occurs is generally between one and two percent each year.

List of Biological HGH Stimulators:

  • GH-RH Growth Hormone-Releasing Hormone binds to GH-RH Receptors in the Pituitary gland.

  • Sex Hormones Testosterone, Estrogen, and other Sex Hormones encourage the release of HGH. Testosterone has been shown to increase the amplitude of HGH Spikes.

  • Ghrelin Ghrelin molecules attach to locations on the pituitary known as Growth Hormone Secretagogue Receptors.

  • Healthy Sleep By reaching the deepest phases of sleep, the brain is encouraged to release increased levels of HGH.

  • Peptide Hormones Certain Peptide Hormones have been shown to increase Human Growth Hormone Production, although these hormones can also affect other systems as well.

  • Dopamine and Clonadine These hormones encourage the Hypothalamus to release GH-RH

  • Propranolol and Arginine These two compounds inhibit the secretion of Somatostatins by the Hypothalamus.

  • Hypoglycemia Low Blood Sugar Inhibits Somatostatin Secretion.

  • Vitamin B3 This vital nutrient is one of the key ingredients which stimulate Natural Growth Hormone Release.

  • Fasting Because the body increases HGH production as a result of lower blood sugar and increased hunger, fasting encourages the body to release enhanced Levels of Growth hormone.

  • Vigorous Physical Activity The body releases spikes of HGH to feed the muscles and cardiovascular system in order to encourage the body to function at a higher level.

List of Biological HGH Inhibitors:

  • Somatostatin Somatostatin is released by the Hypothalamus in order to decrease HGH Production. Some theorize that the Hypothalamus begins to produce too much Somatostatin later in life, contributing to Lower Levels of HGH Production with Age.

  • Growth Hormone and Insulin-like Growth Factor-1 The Hypothalamus increases Somatostatin production when stimulated by HGH and IGF-1 as a form of negative feedback mechanism.

  • Dihydrotestosterone Although Testosterone increases HGH production, Dihydrotestosterone inhibits Growth Hormone Secretion.

  • Glucocorticoids The conversion of Cortisone to Cortisol inhibits the function of Human Growth Hormone. The reverse is also true.

  • Hyperglycemia High levels of Insulin production counteract Human Growth Hormone Function.

  • Certain Medications Many non-biological medicines have an inhibitory effect upon HGH Production for various reasons.

Function of Human Growth Hormone

Human Growth Hormone belongs to a large group of hormones known as Anabolic Hormones. Although HGH is not a steroid like Testosterone or Aldosterone, it still produces a stimulative effect upon systems throughout the body.

Like most peptide hormones, Human Growth Hormone flows through the body, stimulating target receptors located on the outer barrier of cell structures. The most widely recognized function of Human Growth Hormone is to stimulate the growth spurt associated with puberty.

HGH and Height

There are two ways in which it seems that HGH affects height:

First, Peptide Hormones are fat-insoluble. This means that these hormones cannot break through cellular membranes. Because of this, Human Growth Hormone must attach to receptor sites on cell walls. HGH attaches to cartilages cells, encouraging the reproduction and division of chondrocyte cells. This causes the bones to grow longer.

The second pathway in which Human Growth Hormone stimulates height is through the creation of IGF-1 via the liver. Most Human Growth Hormone circulates through the body directly to the liver, where it is converted into IGF-1 and other Growth Factors. IGF-1 encourages the growth and enhanced cell-division of tissues throughout the body, also encouraging changes in height as a result of puberty. IGF-1 encourages organs in the bones known as Osteoblasts to manufacture bone tissue, which directly leads to changes in bone structure. IGF-1 also stimulates chondrocyte activity in a manner similar to HGH.

Why does Human Growth Hormone Increase Height?

HGH is able to cause an adolescent to grow in height because the ends of the bones are still largely made of cartilage. At the end of puberty, growth plates close, preventing the bones from increasing in length. When these plates, also known as Epiphyseal Plates, close, it signals the brain to produce less Human Growth Hormone, leading to the levels that we experience during our late teens and early twenties.

Importance of HGH After Puberty

After puberty, IGF-1 and HGH are responsible for a number of different health functions, including:

  • Increasing Body Fat Metabolism Human Growth Hormone speeds up the rate at which the body burns fat.

  • Optimizing Bone Mineral Density HGH encourages the healthy maintenance of the bones.

  • Stimulating Increased Muscle Mass - Human Growth Hormone encourages the muscles to remain stronger and prevent muscle atrophy.

  • Slowing Down the Rate at which the Body Absorbs Sugar Human Growth Hormone and Insulin work together to regulate blood sugar.

  • Encouraging the Healthy Function of the Pancreas

  • Contributing to Hormone Homeostasis Human Growth Hormone belongs to the Hyothalmic-Pituitary Axis. All of these hormones are intricately connected with one another, and optimal Human Growth Hormone function encourages the body to produce normalized levels of other hormones as well.

  • Strengthening the Immune System Human Growth Hormone encourages white blood cells and other tools of the immune system to replicate more effectively, encouraging fortified immune health.

Human Growth Hormone for HGH Deficiency

It should be clear at this point that Human Growth Hormone Production is vital to optimal health throughout the lifespan. Although the body normally becomes more sensitive to Human Growth Hormone Production with age, the body still inevitably reaches a point at which it does not produce enough HGH to support the healthy function of the body.

For many individuals, Human Growth Hormone Replacement Therapy is a viable option to encourage optimal function deeper into the lifespan. If you feel that you may be a candidate for Human Growth Hormone Replacement Therapy, talk to your doctor.

30 July 2013

Will Human Growth Hormone Prove to be the First Anti-Aging Medication?

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Does Growth Hormone Have Anti-Aging Properties?

It is quite true that we are all going to get old. As a matter of fact, the generation of baby boomers is quickly approaching their mid-fifties, and the number of elderly people in America will continue to increase for another generation. Why then, do we have to resign to growing old in the same way that previous generations were forced to in the ages before us? Must we be weak, frail, fatigued, depressed? Living in fear to take a walk in the park for fear that we may fall?

It is a truism that youth is wasted on those who are young. If such a saying is true, why should the opposite statement also be true? Why must wealth and experience be wasted upon those that are old? Should not older men and women be able to retain their enthusiasm and energy in a grand effort to enjoy their autumn years?

We do not have to take age lying down! We here at the Conscious Evolution Medical Institute have learned that old age is largely a state of mind that has been induced by hormonal deficiencies. It is a state in which the hormones we so enjoyed in our youth have become less bountiful. It makes logical sense that with hrt hormone replacement therapy many of these symptoms can be alleviated or reversed.

One of the most impressive hormones that can be regained through Bio identical Hormone Replacement therapy is Human Growth Hormone. It can allow an older woman or gentleman to live a healthier, longer, and more active life. The greatest point to be made about Human Growth Hormone is that it truly is not all that fantastic of a concept. Growth Hormone is naturally produced by the body, and it is produced in large quantities when we are in our youth. The longer we can retain Growth Hormone, the more we can slow down many of the devastating effects of aging.

It makes perfect sense. Growth Hormone is vital to growth processes within the body. GH supplement is provided to young children who are maligned with slow skeletal growth, and it allows them to grow taller than they would without treatment. The problem is that Human Growth Hormone levels drop at a steady rate in all men and women after they enter adulthood. After decades of research, we now know that Human Growth Hormone provides significant benefits throughout the lifespan. For this reason, we must conclude that Growth Hormone is vital for the maintenance and rejuvenation of the body in adulthood. Research regarding the effect of Growth HRT upon elderly patients provides evidence that the main role of the hormone in adulthood is to allow one to live a longer, healthier life of higher quality.

Where does Human Growth Hormone Originate?

Human Growth Hormone is produced in the anterior area of the pituitary gland which is buried deep within the brain. Human Growth Homrone is a microscopic protein molecule. It has chemical similarities with insulin, though HGH is secreted in brief, sharp pulses after a person exercises or in the initial hours of rest. Human Growth Hormone only stays in the blood stream for a few minutes. For this reason, it in incredibly difficult to measure Human Growth Hormone in serum. Though it does not remain in the blood stream for long, HGH binds to the liver which turns some of the hormone into Somatomedin-C, which is also known well by the name Insulin-Like Growth Factor I (IGF-1) Since IGF-I stays in the blood for up to one and a half days, a blood sample that contains IGF-I proves that HGH is being produced. Normal IGF-I levels in the blood tend to appear in volumes of 200 to 450 ng/ml. However, one third of men and women that are over the age of fifty display levels of HGH that are lower than 200 ng/ml. During puberty, Human Growth Hormone levels are at their peak and IGF-I reaches levels of 600-800 ng/ml or even higher. In normal women and men under the age of forty, less than five percent have levels of HGH that are below 250 ng/ml! After the age of 40 many women and men have a level of Human Growth Hormone that is similar to that of an octogenarian! Human Growth Hormone may be the means by which we can age gracefully.

When IGF-I levels drop under the baseline adult range, energy levels and bone and muscle strength tend to decrease as well. Cell regrowth, tissue repair, vital organ repair, general rejuvenative ability, enzyme production, and hair, skin, and nail revitalization will begin to occur less effectively

Though decreased levels of Human Growth Hormone and increased age are certainly directly correlated, those who lose full function of the pituitary gland, whether through accident, infection, or surgery, will immediately begin to be maligned with acute ill effects.

It is vital to understand that natural HGH will inevitably decline with age!

In those who are utterly lacking a functional pituitary, body composition changes and a shift occurs where the amount of fat increases by 7-25%. Lean mass of the body decreases at a similar rate. Mass and strength of the muscles diminish as well. Studies in regard to bone density show that in those patients with no pituitary input, it seems as though an individual ages by around 15 years by analysis of the density of both the long bones and the spinal bones. As Human Growth Hormone flags, weight increases of as much as fifty pounds occur. Beyond this, there are issues regarding cholesterol as well. Levels of triglycerides go up, and good HDL cholesterol suffers. Cardiovascular complications occur more often, which could be related to the thickening of the vascular walls of the heart. Decreased output by the heart leads to further problems.

Hormonal insufficiencies such as these often lead to people such as these to report a serious decline in their capacity to exercise, and they often suffer from cardiovascular disease, which leads to early mortality. Also, they report issues with loneliness, depression, focus, and fatigue. In general, they just suffer from a general lack of well-being.

Hope on the Horizon: Food and Drug Administration approves Human Growth Hormone for Use by Adults

Recombinant HGH has recently gained approval by the FDA for women and men of adulthood for the therapy of Growth Hormone Deficiency and hypopituitarism. If a person suffers from hypopituitarism, Human Growth Hormone therapy is compatible under the majority of insurance policies. After being approved for therapy, patients are administered Human Growth Hormone treatment and testing under professional supervision. Our experience and the revelations of research provide ample evidence that Human Growth Hormone Replacement Therapy offers benefits to those that have insufficient levels of Growth Hormone. This deficiency is often referred to as Somatotropin Deficiency Syndrome. The Conscious Evolution Medical Institute also provides Human Growth Hormone treatment for patients who suffer from Somatomedin-C (Insulin-Like Growth Factor-1) levels under 200 ng/ml that are approved in our Internal Review Board registry, but these patients are required to pay for their treatment.

Please realize that by undergoing a global hormone replacement regimen, administering progesterone, estrogen, testosterone, thyroid, pregnenolone, or DHEA (other vital hormones which a patient may be co-deficient) when necessary in addition to Human Growth Hormone, one can minimize the costs, side-effects, and dosage of treatment.

Growth Hormone Replacement Therapy Changes

Administration of Human Growth Hormone often leads to substantial changes in the composition of the body: lean muscle mass increases as fat mass percentage is reduced. Using Human Growth Hormone at the modest dosage of 0.003 mg/kg over the course of six months was shown to improve lean muscle mass in 24 patients that had a Human Growth Hormone deficiency (1). Improvements in lean muscle mass have been associated with higher levels of protein synthesis, along with muscle function and mass. The percentage of body fat also drops after six months of Human Growth Hormone administration. The most fat is eliminated from the areas of the trunk and the stomach, rather than the legs, neck, and arms. This fact is evidence that Human Growth Hormone replacement treatment can reverse excess stomach fat associated with Human Growth Hormone deficiency, along with reducing risks of heart problems.

Heart Health and Metabolism of Cholesterols

Human Growth Hormone Therapy for adults also shows is believed to have a positive effect upon cholesterol. In new research, it has been shown that brief regimens of Human Growth Hormone Therapy led to reduced LDL (or bad) cholesterol (7) while also boosting heart function and capacity for exercise. Participants showed higher levels of oxygen intake as well as strength during cycling exercise. Human Growth Hormone has been associated with higher levels of muscle mass and stronger and longer action upon the treadmill (8). Recent research by Fazio has shown that those who have experienced heart failure have shown improvement after being given high dosage of Human Growth Hormone Therapy.

Bone Density

Among the most stunning effects of Human Growth Hormone is its effect upon the skeletal system, muscles, and tissues. It provides a significant level of rejuvenation to these systems. Skin health improves, damaged bones heal more effectively, and significant levels of improved muscular strength have been reported during Human Growth Hormone Therapy. Others have reported that signs of aging are fading from their skin. Sometimes hair regrowth occurs in male hormone replacement therapy patients as well as female patients. These changes provide evidence that testosterone, DHEA, and Human Growth Hormone are anabolic (synthesizing) hormones that significantly rehabilitate tissue of the body. Unfortunately, as we age, catabolic processes lead to faster levels of tissue breakdown. Human Growth Hormone combats the catabolic processes of aging.

The most significant way that Human Growth Hormone effects the skeletal system is through its role in enhancing the body's ability to build and repair the bones. Human Growth Hormone stimulates the proliferation of fibroblast (ligament) and osteoblast (bone) cells in the skeletal system. In recent clinical research using the powerful techniques of single photon absorptiometry and quantitative tomography, marked increases of 4% and 5% were shown in cortical and spinal bone density over the course of twelve months of therapy in adults deficient in Human Growth Hormone (4). In conclusion, it seems that the administration of Human Growth Hormone may lead to an enhancement of multiple organ systems of the body through the positive effect it has upon the skeletal system.

More examples of Human Growth Hormone's anabolic effects include muscle gain and increased appetite, increased capacity for exercise, increased capacity of the lungs, and increased would rehabilitation. Many also report that liver spots, also known as senile keratoses, begin to fade after eight weeks of Human Growth Hormone Therapy.

Side-Effects of Low Dosage Human Growth Identical Hormone Replacement Therapy.

Human Growth Hormone dosage is a vital consideration in those who suffer from Human Growth Hormone Deficiency. Overdosage of Human Growth hormone is associated wit many signs of excess Human Growth Hormone. Among these symptoms are hypertension, carpal tunnel, and excess fluid retention. However, by using more modest doses of Human Growth Hormone, it was demonstrated by Bengtsson that only mild side-effects such as slight joint pain and mold fluid retention occur. Only a single case of carpal tunnel was discovered. In each of these cases, further restriction of the Human Growth Hormone dose lead to full elimination of the side-effects. Another clinical study only used a small dose of 0.01 mg/kg, which was injected three times each week. In this study, there were zero side-effects reported (8). Many studies provide evidence that says that low dosage Human Growth Identical Hormone replacement therapy generally only causes modest side-effects, if any.

Benefits of Hormone Replacement Therapy with HGH.

Improve Body Composition: Boost muscle mass and reduce fat for a shift in body composition of as much as 20 pounds. This change can lead to higher sex drive, as well as enhanced physical well-being and self perception.

Improve Energy: Human Growth Hormone patients report higher levels of energy without the need for afternoon snacks, stimulants, caffeine, or cigarettes. This energy boost helps them become more confident in their self control and enhances their capacity for exercise.

Improve Focus: An intriguing yet untested potential benefit of Human Growth Hormone is a return of mental focus and enhancement of memory. Since Human Growth Hormone provides improvement to the intracellular and vascular systems which support the cells, it is not at all surprising that these benefits have been reported in individuals.

The Future

Many fundamental questions remain regarding the exact medical definition and preferred treatment for partial versus total Human Growth Hormone Deficiency. Also, it is not clear whether all of the realized positive effect of full Human Growth Hormone Replacement Therapy will occur in those that undergo low dosage or combination treatments. Even so, is has already been made clear that even small doses that do not result in potential side-effects sufficient level may be sufficient for some to reach their metabolic goals. We here at the Conscious Evolution Medical Institute hope that our continued clinical evaluations will help lead to more efficient usage of Human Growth Hormone, as well as help reveal more of this wondrous therapy's benefits while eliminating incidence of increased cardiovascular and general morbidity.

Works Cited

Cuneo, Salomon, and Hesp, et al. Treatment effects of Recombinant HGH upon Metabolism and Body Composition among Adults with Growth Hormone Deficiency. New England Journal of Medicine 1989; Issue 321: Pages 1797-03.

Bengtsson. Consequences of Growth Hormone Deficiency in Adults. Acta Endocrinoligica 1993; Volume 128: Pages 2-5.

Cuneo, Salomon, Wiles et al. Effects of Human Growth Hormone Treatment Among Adults Whom are Deficient. Applied Physiology Journal 1991; Volume 70: Pages 695-700.

Halloran, Tsatsoulis, Whitehouse et al. Increased Bone Density after Human Growth Hormone Therapy Upon Deficient Adults. Journal of Clinical Endocrine Metabolism 1993;Volume 76: Pages1344-48.

McGauley, Cuneo, Salomon et al. Psych. Self-perception changes due to Growth Hormone Treatment in Adults with Human Growth Hormone Deficiency. Hormone Research 1990; Volume 33(Supplement 4): Pages 52-54.

Bengtsson, Eden, Lonn et al. Therapy of Adults with Human Growth Hormone Deficiency with Recombinant Growth Hormone therapy. Journal of Clinical Endocrine Metabolism 1993;Volume 76:Pages 309-17.

Johnston, Bengtsson. Effects of Growth Hormone and its Deficiency upon Heart and Lipids. Acta Endocrinologica 1993;Volume 128(Supplement 2):Pages 69-70.

Amato, Carella, Fazio et al. Heart Structure, Metabolism of Bone, and Body Composition Heart Structure in Growth Hormone-Deficient Adults Effects of Human Growth Hormone Replacement Therapy at Mild Dosage. Journal of Clinical Endocrinology and Metabolism. 1993;Volume 77:Pages1671-76.

Fazio, Sabatini, Capaldo, et.al. Test study of GH in the treatment of cardiomyopathy. New England Journal of Medicine. 1996;Volume 334:Pages 809-14.

The above information does not provide sufficient evidence to self-diagnose a particular procedure or treatment. It should not lead one to believe that this is the only treatment option available.

22 December 2012

HGH injections treating Polio Virus and Post Polio Syndrome

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Human Growth Hormone Patient Profile

Human Growth Hormone Replacement Therapy continues to amaze. New uses for this potent therapy are being continually researched and uncovered. Although today, HGH Hormone Replacement is only available for a few particular indications, in the future, there is no doubt that its uses will continue to grow in number.

Human Growth Hormone Post-Polio Treatment

In today's article, we will discuss the benefits of Human Growth Hormone Replacement Therapy experienced by a man named Chris. Chris was diagnosed with polio when he was a young child. Although Polio is all but eradicated in the United States today, there are still many that suffer from the after-effects of this devastating virus.

Although Chris eventually beat the disease, he was stricken with a few chronic issues as a result of his battle. For six months, Chris suffered from paralysis of one of his legs. Although the paralysis eventually wore off, Chris still suffered from a partial loss of mobility in his leg. He was forced to wear a brace until he was thirteen years old, which extended from his hip to his knee.

In addition to the mobility issue he suffered as a result of polio, his leg also did not grow appropriately, leaving his affected right leg smaller, shorter, and weaker than his healthy left leg. Even his foot was smaller two sizes smaller, in fact. Chris always worked through his disability, though, and regained a significant amount of function over the years.

The Debilitating Effects of Post-Polio Syndrome

Later in his life, his doctor officially diagnosed him with a disorder known as Post-Polio Syndrome. This disorder usually occurs later in life in patients that experienced Polio at a young age. The body starts to slow down and degrade over time, and the muscles start to weaken, leading to an overpowering sense of fatigue.

Patients that suffer from Post-Polio Syndrome often have to take numerous drugs in order to alleviate the symptoms of the disorder. Chris was prescribed quite a few, including sleeping pills to soothe his restless nights, and pain medications to alleviate chronic pain, and muscle relaxers in order to reduce the frequency and severity of twitching muscles. On top of that, they sharply suggested that he reduce his physical activity in order to reduce agitation and preserve energy.

Although Chris was on a cocktail of medications, he was told that even this was likely not enough. For many, the long-term prognosis for Post-Polio Syndrome is rather depressing a life bound in a wheelchair, experiencing continually degrading, physical function which forces many to be dependent on friends, family, or health care professionals.

Chris couldn't imagine a life like this for himself. Even in the face of his circumstances, he always lived life to the fullest, and the prospect of not being able to live life his own way was a depressing concept. At first, the physiological and psychological effects of Post-Polio Syndrome wreaked havoc upon his once active and vibrant life. Because he was forced to live a lifestyle without exercise, his weight began to increase quickly and dangerously.

The disease itself left him increasingly tired and exhausted, enhanced by his lack of physical activity. The support groups were supposed to help him come to terms with his new life, but they only frustrated him more and more. He was frustrated because everyone seemed to be giving up and settling for an unfulfilling life of progressive decline.

Then He Found Human Growth Hormone

His despair in regard to his circumstances drove him to seek other opinions and treatment options. Chris had heard that there were new alternative treatments, and he wanted to take the chance to improve his condition. In 2002, he learned that Post-Polio Disorder was associated with Human Growth Hormone Deficiency, and that HGH Hormone Replacement Therapy had the potential to help people like him reverse the symptoms and severity of Post-Polio Disorder.

Benefits of HGH

Human Growth Hormone Replacement Therapy has long been known to provide a number of different benefits to patients suffering from HGH Deficiency, including:

  • Improved Sleeping Habits

  • Decreased Fatigue

  • Enhanced Muscle Mass

  • Increased Fat Burning Potential

  • Improved Cardiovascular Health

  • Alleviation of Depression and Anxiety

Doesn't Chris sound like the poster-child for Human Growth Hormone Deficiency?

The doctor that prescribed Chris HGH Hormone Replacement Therapy was a lot like him. He also suffered from Post-Polio Syndrome, and actually used HGH Injections himself, in order to treat the symptoms of the disease. In addition to HGH Deficiency, Chris also learned that he could also potentially benefit from Testosterone Replacement Therapy, and his doctor prescribed him a Testosterone Cream. Post-Polio Disorder is largely a disease of Hormone Imbalance, and by correcting this hormone Deficiencies, he had hope that he could resolve all the other issues adversely affecting his health.

How Did HGH Benefit Chris?

Within a month of starting Hormone Replacement Therapy, Chris started to notice some significant changes in his physical ability. Although Chris could still walk, he no longer had the capacity to carry himself up the stairs without pulling himself up using his hands. After starting Hormone Replacement Therapy, he found that he was able to walk up the stairs using his lower body alone, something he had not been able to do for well over a year.

As time passed further, his life only got better. After nine months, he dropped eighteen pounds and even became fit enough to start swimming again! Although he didn't have the endurance he did when he was younger, he could still swim as long as half of a mile as long as he took brief breaks. Chris was no longer shackled by fatigue and his self worth began to soar.

Long Term Effects of HGH Hormone Replacement Therapy

Chris continued to take the therapy. After nearly two years, he still maintained a healthy weight, and he is still active and energetic. The only issue that he has had is a slight weakness in one of his hands, which is a small price to pay for getting his life back.

Chris experienced very minor side effects as a result of treatment. In the initial week, he experienced a bit of water retention in the legs, but as his body acclimated to treatment, the edema naturally faded. It should be noted that some other patients do experience certain side-effects, including joint pain, carpal tunnel syndrome, and increased blood pressure.

Why Hadn't HGH Hormone Replacement Therapy Been Recommended Before?

Although Chris experienced incredible benefits through the utilization of Human Growth Hormone, the use of HGH Hormone Replacement Therapy for this purpose has not been studied deeply. This is likely because polio is all but defeated today in the United States. In spite of this, there are still many older individuals that suffer from post-Polio Syndrome that would likely benefit from enhanced Human Growth Hormone Levels.

Although Polio is very nearly eradicated, there are still many worldwide that could still benefit from this treatment. This is also another data point which shows that HGH Hormone Replacement Therapy has a number of significant, well documented benefits.

In the last decade, it has been discovered that one of the most life-altering symptoms of Post-Polio Syndrome is a severe Deficiency in Human Growth Hormone later in life. By restoring HGH Levels, it is possible to help these patients live a longer, healthier, and happier life.

What Does This Have To Do With Me?

Although Polio is no longer an issue in the United States, or most other countries in the world, the effects of HGH Injections upon patients with Post-Polio Disorder is incredibly enlightening. Polio is just one of a number of factors which can cause a man or woman to experience severe HGH Deficiency. Other potential causes include:

  • Surgery

  • Radiation

  • Pituitary Tumors

  • Hereditary Disorders

  • Advancing Age

Symptoms of HGH Deficiency

All of these issues have the potential to reduce or eliminate a patient's ability to produce healthy levels of Human Growth Hormone. Most of the symptoms that Chris experienced were the hallmark symptoms of Growth Hormone Deficiency, including:

Fatigue HGH is a potent, metabolic hormone. If the body isn't producing enough Human Growth Hormone, energy levels plummet. This decline in energy has a devastating impact upon health and vitality.

Increased Weight Gain These same metabolic processes also help keep weight in check. Without appropriate physical activity, or the energy to engage in that activity, the body starts to accumulate fat. This body fat tends to build around the midsection.

Decreased Muscle Mass Human Growth Hormone and IGF-1, as well as Testosterone, are central to maintaining strong and healthy muscles. As HGH Levels decline, patients are more prone to issues related to frailty, which prevent them from doing simple things like walking up a flight of stairs with ease.

Depression and Irritability HGH Deficiency also has a powerful impact on psychological health, through a mixture of physiological changes and changes in self-worth.

The use of HGH Hormone Replacement Therapy helped Chris. Could it help you?

19 November 2015

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Three sided solution: Testosterone + HCG + Arimidex

If your doctor only prescribes testosterone by itself, you will probably have a rough ride. The tendency is for you to feel great the first couple months, while you increase testosterone levels, followed by a slow deterioration, once your estrogen creeps up.

High estrogen negates a lot of the positives from testosterone therapy, resulting in the same symptoms of low testosterone you had in the first place!

The solution is to add a drug called Arimidex. It's called an aromatase inhibitor, which essentially blocks the conversion of testosterone to estrogen. It has the effect of increasing testosterone levels, while keeping your estrogen low.

Once you have your testosterone and estrogen solved, it's time to stop the next inevitable decline? Shrinking testicles.

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