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Written by Dr. Welsh, Article reviewed and edited by Dr. Fine M.D..
Published on 02 April 2021

While pretty much everyone knows that Testosterone is critical to male health and physiological function, most people aren't aware of the actual relationship between Estrogen and the male body. While women produce far more Estrogen than men, the colloquial feminine hormone is still very important for men's health. On the other hand, too much Estrogen can lead to very real problems for guys.

How Is Estrogen Important for Men?

Estrogen is actually a shorthand for three hormones called Estriol, Estradiol, and Estrone. Estradiol is the most important to men and is intricately involved in sexual ability and function. Testosterone and Estrogen are in delicate balance in both sexes; it's just that the balance of power with these hormones is vastly different between men and women. Men produce a little Estrogen and a lot of Testosterone. Women make a little Testosterone and lots of Estrogen. Specifically, men should produce around fifteen times more Testosterone than Estrogen. The ratio of Testosterone vs. Estrogen is more important than the values themselves.

How Do Men Make Estrogen?

Men make Estrogen via an enzyme named aromatase. Aromatase is abundant in fat cells. This is important because obesity is one of the leading causes of sex hormone imbalance in men. The more body fat a man carries, the more Estrogen that his body produces. The hypothalamus uses circulating Estrogen Levels as a means to modulate Testosterone Production. Perhaps ironically, the more Estrogen that your body is converting, the less your brain signals for the production of Testosterone, which can lead to symptoms of Testosterone Deficiency. In some cases, men may not produce enough Estrogen via aromatase. This can lead to issues with fertility and also contribute to metabolic problems and abnormal bone development.

Causes of High Estrogen

Elevated Estrogen is caused by many different factors. As mentioned above, weight gain leads to increased Estrogen. Men are also likely to produce more Estrogen due to stress and aging, though aging sometimes leads to lower Estrogen production. Certain tumors can also increase Estrogen expression. Endocrine Disrupting Chemicals can also increase Estrogen or suppress Testosterone production. These chemicals can reproduce the effects of Estrogen. Steroids can also increase Estrogen Levels because some excess Testosterone is turned into Estrogen.

Symptoms of Elevated Estrogen Levels

  • Gynecomastia
  • Pulmonary Hypertension
  • Depression
  • Weight Gain
  • Migraines
  • Erectile Dysfunction
High Estrogen is also evidence that a man is at high risk of several dangerous conditions, including prostate cancer, breast cancer, stroke, blood clots, and diabetes. Elevated Estrogen is also a symptom of Prostate Cancer.

Causes of Estrogen Deficiency

Because Testosterone Production and Estrogen Expression are strongly linked, Testosterone Deficiency can also lead to symptomatic Low Estrogen Levels. There are several conditions that also suppress the production of Estrogen, including anorexia, hemochromatosis, autoimmune disorders, and cardiovascular issues. Low Estrogen is often a symptom of other health issues.

Symptoms of Estrogen Deficiency

  • Insulin Resistance
  • Weight Gain
  • Osteoporosis
  • Bone Loss
  • Late Puberty
  • Heart/Arterial Disease
  • Trouble Ejaculating
  • Depression


Written by Dr. Welsh, Article reviewed and edited by Dr. Fine M.D..
Published on 24 March 2021
Healthy HGH Levels are critical to achieving and maintaining a state of ideal wellness and vitality. While HGH Deficiency is uncommon during early adulthood, it becomes more common as men and women get older. Until recently, all FDA-Approved Growth Hormone Therapy Treatments required daily injections to maintain effectiveness. This is different from other hormone treatments such as Testosterone Therapy. With Testosterone, some formulations only require administration once every 2-4 weeks. Luckily, as medical science advances, new treatment options evolve. In late 2020, a new form of HGH Treatment was approved, which only requires injections on a weekly basis: Sogroya (generic name somapacitan). Sogroya is derived from the same base of Bio-Identical Human Growth Hormone as other brands of HGH Injection. Unlike other available treatment options, somapacitan is specially formulated to release slowly into the bloodstream. Other Therapeutic Growth Hormone options are metabolized quickly after injection. Sogroya is the end-result of the scientific innovations of Novo Nordisk.

How to Use Sogroya

Sogroya is delivered the same way as older HGH formulations. Sogroya is administered subcutaneously, just below the top layer of the skin. This type of injection is nearly painless, and there are HGH Injection Pens that make the process even simpler. Sogroya is developed to be used with a Pen.

Who Qualifies for Sogroya?

Sogroya is indicated for adults that have been clinically diagnosed with Human Growth Hormone Deficiency. Most other forms of HGH Therapy are available for all ages, but Sogroya is only intended for adult patients. In the future, Sogroya availability may be expanded to all ages, but more testing is required. Human Growth Hormone Deficiency is diagnosed by measuring Serum IGF-1 Levels in the blood. Baseline HGH cannot be easily measured because it is released in short bursts, but IGF-1 Levels remain fairly constant in the bloodstream, providing the prescribing doctor with a means to accurately estimate HGH Levels and make a diagnosis.

Benefits of Sogroya

Sogroya provides the same benefits to patients as older forms of HGH Therapy. For patients with Clinical Growth Hormone Deficiency, Sogroya can increase muscle mass, improve cognition, ward off fatigue, and encourage weight loss via the breakdown of body fat. There is also strong evidence that HGH Treatments like Sogroya can improve immune health and enhance the body's natural healing processes. While Sogroya is not without risks, those risks are comparable to other available brands of Growth Hormone Injection.

Interested in Sogroya? Contact our Licensed Hormone Clinic for More Information!

Sogroya HGH Therapy represents an exciting step forward in the treatment of Hypopituitarism. If you are interested in switching your Growth Hormone Prescription to Sogroya, our Board-Certified Hormone Specialists may be able to help. If you've never been diagnosed with HGH Deficiency, we can help you undergo the prerequisite testing necessary to see if you qualify!


Written by Dr. Welsh, Article reviewed and edited by Dr. Fine M.D..
Published on 10 February 2021
The Thyroid Gland is a tiny organ located just beneath the Adam's Apple. Despite its diminutive size and butterfly-like shape, it has a powerful effect on human health and physiology. A healthy thyroid is one of the keys to unlocking full vitality. Hypothyroidism is a condition in which the Thyroid gland is under-active, and it's a common condition that impacts the lives of around 20 million people in the United States. Hypothyroidism is prevalent, but it is also distressingly under-diagnosed. It's estimated that approximately 60% of people with Hypothyroidism don't even know it!

What Does the Thyroid Do?

The Thyroid Gland manages the distribution of energy to meet the human body's disparate needs. The Thyroid is essentially the control center for metabolism. That means that if the Thyroid goes haywire, it can affect pretty much every system in the human body. The thyroid gland is most well-known for its effects on metabolism and thermoregulation, but it's also imperative to several other aspects of human function. It promotes good vision, strength, and fertility. It also maintains the muscles and promotes healthy psychological and cognitive function. Even your nails and skin benefit from a functional Thyroid. Because the Thyroid's effects are so important and so widespread, it can often make accurate diagnosis of Thyroid Problems a challenge.

What Are Some Signs That I Should Have My Thyroid Checked?

Thyroid Issues are hard to pinpoint because there is no checklist of symptoms set-in-stone that every patient will experience. Some people may display small signs of Thyroid Imbalance, such as a disrupted sleep cycle, the onset of anxiety/depression, or slight changes in baseline metabolism/body temperature. Other people may experience more severe symptoms such as sudden and dramatic changes in blood pressure/blood sugar that can be very dangerous. If you've noticed recent changes in your mental, cardiovascular, or neurological health, this could be a sign of Thyroid Issues. Tough-to-treat anxiety and depression are very common signs of Thyroid Problems. If you think you may have Thyroid Problems, even if you notice very few symptoms, you should get yourself checked out. Most patients only experience a small set of symptoms that they can perceive, and other symptoms are diagnosed by a doctor.

Hypothyroidism vs. Hyperthyroidism

As previously mentioned, the most common form of Thyroid Disorder is Hypothyroidism. This condition suppresses metabolic activity in various ways system-wide. It slows down body and mind, decreasing your ability to initiate and sustain increased activity levels. It also slows down healing and regeneration, suppresses heart rate, limits cognitive capacity, and reduces the rate at which various organ systems operate. While severe Hypothyroidism becomes easier to diagnose, early signs can appear relatively mild, even if your health and vitality would benefit greatly from treatment. Hyperthyroidism, on the other hand, is a condition in which your Thyroid is signaling for too much activity. While not nearly as common as Hypothyroidism, both conditions are very dangerous to your long-term health if the they reach a certain level of severity. Some of the more noticeable hyperthyroidism symptoms include racing mind, rapid heartbeat, anxiety, diarrhea, increased appetite, and unexplained weight loss.

Getting Appropriate Treatment for Thyroid Issues

One issue with Thyroid Treatment in the United States is that you may have to go to a Hormone Specialist or reach out for a second opinion to get the treatment that you need. Sleep cycles, heart rate, blood pressure, and cholesterol all provide strong evidence for diagnosis and treatment. While Thyroid Hormone Treatments are very effective and have a very low risk of significant side-effects, some doctors may be more reluctant to sign off on Thyroid Hormone Testing than others. The medical professionals associated with the American College of Endocrinology believe that all patients that suspect Thyroid Issues should get tested for Thyroid Disorders. Early testing and diagnosis can save a lot of headaches later on. While doctors try to work in your best interest, if you firmly believe that Thyroid Insufficiency or Hyperthyroidism is having a negative impact on your life, make the active effort to ensure you get the treatment that you deserve.

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Testosterone Therapy Benefits

Correctly performed testosterone therapy can be your ticket to health.

Three sided solution: Testosterone + HCG + Arimidex

If your doctor only prescribes testosterone by itself, you will probably have a rough ride. The tendency is for you to feel great the first couple months, while you increase testosterone levels, followed by a slow deterioration, once your estrogen creeps up.

High estrogen negates a lot of the positives from testosterone therapy, resulting in the same symptoms of low testosterone you had in the first place!

The solution is to add a drug called Arimidex. It's called an aromatase inhibitor, which essentially blocks the conversion of testosterone to estrogen. It has the effect of increasing testosterone levels, while keeping your estrogen low.

Once you have your testosterone and estrogen solved, it's time to stop the next inevitable decline? Shrinking testicles.

This is where HCG (human chorionic gonadotropin) comes in. It prevents both infertility and testicle shrinkage. Your testicles shrink because your body thinks it doesn't need to make testosterone anymore.

For some, small testicles may seem like just a cosmetic problem. But HGC does more than increase testicle size, it also increases adrenal function, which can have positive effects on well-being, libido, and energy.

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