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A BRIEF GUIDE TO ENDOCRINOLOGY
Written by Dr. Welsh, Article reviewed and edited by Dr. Fine M.D.. Published on 02 November 2020
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Endocrinology is an area of medical science that is devoted to the study of Hormones. The Endocrine System represents the variety of organs and glands which are responsible for hormone production and regulation. Endocrinologists are heavily involved in the investigation of medical disorders and conditions which impact human health via Hormone Imbalance, including infertility, Low-T, HGH Deficiency, Thyroid Insufficiency, Obesity, Hypertension, and more.
The Endocrine System is incredibly complex, but some of the central glands in the system are the Ovaries, Testes, Pancreas, Adrenals, Parathyroids, Thyroid, Pituitary, Pineal, and the Hypothalamus.
What Do Hormones Do?
Every Hormone in the body has at least one job to do. In the case of many hormones, such as HGH and Serotonin, they perform various functions depending on physiological circumstances. Hormones are often called Chemical Messengers because their job is to help different parts of the body communicate. The end-point where a Hormone completes its task is known as the Target and can be located pretty much anywhere in the body. It's estimated that as many as forty hormones can be active in the bloodstream at a time.
The Following is a brief list of functions modulated by Hormones:
- Mood
- Reproduction
- Sexual Function
- Metabolism
- Growth and Physical Development
- Blood Sugar Regulation
The Perils of Hormone Imbalance
Our hormones interact in a very complex way. Proper function depends on Hormone Cascades, which are delicately balanced. If one hormone isn't being produced correctly, it affects entire systems. The human body is pretty great at maintaining Hormone Balance on its own, but sometimes things can get out of whack in a way that requires outside intervention. Endocrinologists are doctors that specialize in the area of Hormone Health.
Parts of The Endocrine System
Adrenal Glands
The Adrenals are critical to the regulation of blood pressure and salt/water balance. These glands are situated just above the kidneys. They also play a pivotal role in metabolism and stress response. While they produce sex hormones throughout the lifespan, they also trigger the development of the sex organs themselves. The three main classes of hormones that the adrenal glands produce are androgens, glucocorticoids, and mineralocorticoids.
Hypothalamus
The Hypothalamus is considered the prime control center of the brain. It links the nervous system and the endocrine system via the Pituitary. The Hypothalamus produces many precursor hormones and also controls a lot of involuntary duties such as thirst, hunger, and temperature regulation.
Pituitary Gland
The Pituitary is tiny—about the size of a single pea—but it has huge responsibilities. The Pituitary releases hormones which act upon other glands such as the reproductive organs, the adrenals, and the thyroid. It's often called the Master Gland for this reason. Growth, sexual function, and renal function are all high priorities for the Pituitary.
Pineal Gland
The Pineal gland is critical to the circadian rhythm. It's deep in the core of the brain and is responsible for the production of melatonin, which controls our sleeping habits.
Pancreas
The Pancreas does double-duty as a link between the Digestive System and the Endocrine System. The Islets of Langerhans are the parts of the Pancreas responsible for hormone production. The Pancreas helps control metabolism and blood sugar, and pancreatic malfunction is the prime cause of Diabetes.
Parathyroid Glands
The human body has four Parathyroid glands, all around the size of a pencil-tip. They are located behind the thyroid, deep in the neck. The glands are responsible for controlling calcium levels, not only in the bones but throughout the body. The glands produce Parathyroid Hormone to modulate calcium and also interact with the intestines to draw calcium from the digestive tract.
Thyroid gland
The thyroid is also located in the neck and is responsible for converting Iodine into T3 and T4. These hormones are critical to heart rate, temperature, and blood pressure. They also modify how the body responds to the influence of other hormones. The thyroid also down-regulates calcium.
Testes
Testes are the male glands. The Testes produce Testosterone and other sex hormones, which both control sexual development and support sexual health. Testosterone also has unique effects on several different systems.
Ovaries
As opposed to the testes, women have Ovaries as their primary sexual glands. The ovaries are responsible for spurring sexual development. The ovaries produce both progesterone and estrogen, which are both vital to menstrual regulation and pregnancy.
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HOW MUCH DOES TESTOSTERONE CONTROL MEN'S BEHAVIOR?
Written by Dr. Welsh, Article reviewed and edited by Dr. Fine M.D.. Published on 07 October 2020
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While Testosterone is undeniably critical to male physiology, it's essential to understand the wide range of effects that Testosterone has on men. Testosterone clearly impacts the way that men act and think in a variety of ways. It's correlated with increased assertiveness and confidence as well as increased aggression, for example. There's no doubt that Testosterone has some effect on male behavior, but it's also possible that Testosterone is somewhat of a red herring when it comes to many factors that differentiate men and women psychologically.
Testosterone, unlike most hormones, has a very particular mystical aura surrounding its effects. Along with confidence and assertiveness, the quintessentially male hormone is also associated with increased promiscuity, athletic prowess, and willingness to take risks.
Testosterone and the Endocrine System
Testosterone is one of a number of Steroid Hormones, along with progesterone, Estrogen, and others. Cholesterol is the foundation of Testosterone. While Testosterone is dominant in men, it's also produced in much smaller amounts by women. Testosterone is just one actor in the endocrine system, and the human body functions at its peak when all of these hormones are in proper alignment. Just like women need some Testosterone, men require some level of Estrogen for health and fertility.
These Hormones do more than just promote sexual function, however. They also support liver function, cardiovascular health, and bone structure, just to name a few key influences.
Testosterone and Psychology
While Testosterone is linked with several traits associated with toxic masculinity, it's quite possible that the hormone gets a bad wrap. Early research in the late 19th and early 20th century clearly correlated Testosterone with aggression in animals. As we've learned more about how Testosterone works over the last century, it's clear that our actions and circumstances influence Testosterone Production. There are feedback mechanisms at play. While Testosterone increases the tendency toward aggression, our free will certainly play a role as well.
Numerous recent studies have begun to explore the link between Cortisol and Testosterone. Cortisol is the body's primary stress hormone and is built from the same component parts as Testosterone. It's theorized by many that Testosterone is produced in anticipation of aggression and competition, just as Cortisol is released in response to stress. Testosterone also appears to act as a sorting mechanism for dominance. Studies have shown that success in competition leads to temporarily increased Testosterone, while defeat is correlated with a drop in Testosterone. This is true not only for competitors, but for fans!
This is one area that is very different for men and women. Among men, success and competition have the potential to create a feedback loop that induces ongoing aggression. In women, this is not the case.
Self Control and Testosterone
So it's clear that Testosterone induces aggression, but can nurture mitigate the negative risks associated with Testosterone? One study shows that Cognitive Behavioral Therapy during adolescence can help boys and men control how their bodies and brains respond to confrontation. Therapy reduced aggression during adulthood and also produced less Testosterone during provocation. Men release Testosterone in response to situations that suggest the need for aggression, but cognitive processes can keep the mind in control of the emotions.
Interestingly enough, studies show that women and men both have a similar capacity for anger. The differences lie in the way that anger is expressed. Men are far more likely to respond with physical aggression than women. It's believed that Testosterone makes men more likely to convert anger into force and action than women.
In the end, it's important to understand that Testosterone is not in the driver seat of male psychology. Men ultimately have control over our actions, and our choices and willpower can keep the potential negative consequences of Testosterone in check. Testosterone is just a tool, and men must wield that tool thoughtfully.
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TESTOSTERONE SHOCK THERAPY MAY BE AN EFFECTIVE PROSTATE CANCER TREATMENT
Written by Dr. Welsh, Article reviewed and edited by Dr. Fine M.D.. Published on 23 August 2020
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Testosterone Therapy is popular among American Men, but it's not for everyone. For example, Testosterone exacerbates Prostate Cancer. Almost 200,000 men are diagnosed with Prostate Cancer each year. Researchers continue to search for innovative ways to treat Prostate Cancer effectively. A study from 2016 investigates a treatment method that may seem counterintuitive—Testosterone Shock Therapy. One patient in this study experienced complete remission resulting from treatment.
Testosterone Normally Makes Prostate Cancer Worse
Under normal circumstances, Testosterone exacerbates Prostate Cancer, but a high-dose of Testosterone appears to kill the Prostate Tumor. In order to eliminate Prostate Cancer cells, researchers alternated between delivering high doses and extremely low doses of Testosterone. This treatment is also known as Bipolar Androgen Therapy.
Intriguingly, researchers do not currently fully understand how this works, but the results are readily apparent. The long-term goal is to learn the mechanisms behind this new treatment and figure out how best to include Testosterone Shock Therapy, among other treatment options.
Bipolar Androgen Therapy Helps Patients Grapple With Prostate Cancer
Patients underwent three phases of alternating High/Low Testosterone exposure. This pattern overloads Prostate Cancer Cells then starves them. It's hypothesized that this alternating pattern helps kill off the cells faster than simply cutting them off from their fuel source. Each Testosterone Cycle consisted of a single injection of High-Dosage Testosterone every four weeks. During this same period, they received medication to shut down the natural production of Testosterone.
The easiest way to monitor Prostate Cancer activity is by measuring Prostate Specific Antigen (PSA) Levels. The higher that PSA Levels are beyond baseline, the more aggressive the tumor. Among patients in the experiment, 47 men experienced lower PSA Count due to Testosterone Shock Treatment. The one lucky patient with total remission had PSA Levels fall to zero for at least 22 treatment cycles. Shock Treatments helped many patients stabilize their Prostate Cancer, halting its progression. It's clear that this treatment can help at least some patients significantly reduce the mortality risk associated with Prostate Cancer.
Bipolar Androgen Therapy Alternative to Androgen Deprivation Therapy
For decades, it's been supposed that Testosterone is the primary reason that Prostate Cancer gets out of hand. Indeed, treatments that shut down Testosterone Production or block Testosterone Activity have proven useful and effective. It's believed that Bipolar Androgen Therapy works because it interrupts the proliferation of Prostate Cancer Cells by disrupting cellular division. The alternating feast/famine Testosterone Cycle appears to breakdown the DNA of these rogue cells.
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Testosterone Therapy Benefits
Correctly performed testosterone therapy can be your ticket to
health.
Three sided solution: Testosterone + HCG + Arimidex
If your doctor only prescribes testosterone by itself, you will
probably have a rough ride. The tendency is for you to feel
great the first couple months, while you increase testosterone
levels, followed by a slow deterioration, once your estrogen
creeps up.
High estrogen negates a lot of the positives from testosterone
therapy, resulting in the same symptoms of low testosterone you
had in the first place!
The solution is to add a drug called Arimidex. It's called an
aromatase inhibitor, which essentially blocks the conversion of
testosterone to estrogen. It has the effect of increasing
testosterone levels, while keeping your estrogen low.
Once you have your testosterone and estrogen solved, it's time
to stop the next inevitable decline? Shrinking testicles.
This is where HCG (human chorionic gonadotropin) comes in. It
prevents both infertility and testicle shrinkage. Your
testicles shrink because your body thinks it doesn't need to
make testosterone anymore.
For some, small testicles may seem like just a cosmetic
problem. But HGC does more than increase testicle size, it also
increases adrenal function, which can have positive effects on
well-being, libido, and energy.
 HCG MoleculeHCG Molecule - Click For Gallery
 HGH MoleculeHGH Molecule - Click For Gallery
 HGH DeclineHGH Decline Gallery
 TESTOSTERONE MoleculeTestosterone Molecule - Click For Gallery
 TESTOSTERONE DeclineTestosterone Decline Gallery
 SERMORELIN MoleculeSermorelin Molecule - Click For Gallery
 IGF-1 MoleculeIGF-1 Molecule - Click For Gallery
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