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How Does Human Growth Hormone Deficiency Impact Sleeping Habits: A Clinical Study
Researchers have long been aware that HGH Deficiency is strongly correlated with an increased incidence of sleeping problems, and in recent years, more time and effort have gone into exploring that correlation.
How Were Patients Selected for this HGH Sleep Study?
One study, published in 2010, analyzed thirty patients with Abnormally Low Growth Hormone Levels from four different University medical centers: the University of Pisa, Italy, the University of Liege in Belgium, the Free University of Brussels, and the University of Chicago. Patients were diagnosed with Human Growth Hormone Deficiency using a method known as the Insulin Tolerance Test. Patients were selected for this study if they showed less than three micrograms per liter after drinking Glucose Solution. Twenty-four of the patients suffered from Adult-Onset Hypopituitarism, while six were diagnosed early in life with Childhood-Onset Hypopituitarism.
Patients that were selected for study had not taken Bio-Identical HGH Injections for a minimum of six months before they were selected, and some participants had never used Bio-Identical Human Growth Hormone Injections. Subjects were screened for a number of conditions, and were turned away if they showed any signs of Diabetes, Hyperprolactinemia, Psychiatric/Neurological Disease, chronic infection, heart problems, kidney problems, liver disease, or drug/alcohol abuse.
Also, patients that had traveled three time zones or more in the previous two weeks were excluded, as were people that were shift workers in the prior three months. Finally, participants had to be off of sleeping medications for a minimum of 90 days.
Adult-Onset HGH Deficiency Causes
The source of Hypogonadism varied from patient to patient. In twelve of the thirty patients, Adult-Onset Hypopituitarism was the result of a pituitary issue that did not involve other parts of the endocrine system. Ten patients had their pituitary removed via surgery. One patient experienced the death of a pituitary tumor which suppressed HGH Levels, and one patient suffered from the same issue, but from the stalk of the pituitary. None of these patients suffered from Diabetes Insipidus.
The second group of patients had pituitary issues that could have been partially the result of hypothalamic insufficiency. Two patients had a tumor removed from the pituitary and suffered from Diabetes Insipidus. One patient received radiation therapy to remove a pituitary tumor. Two patients experienced HGH Deficiency as a result of Craniopharyngioma. One patient had a pituitary tumor break down while also suffering from Diabetes Insipidus. There were two patients that had lesions both of the hypothalamus and the pituitary, resulting from histiocytosis and neurosarcoidosis, respectively.
Childhood-Onset HGH Deficiency Causes
In the Childhood-Onset Hypopituitarism group, six of the ten patients experienced their deficiency as a result of a known genetic predisposition to HGH Deficiency. One patient suffered from Hypothalamic Insufficiency that led to HGH Deficiency. Three others suffered from Hypopituitarism resulting from the appearance or removal of tumors from the Pineal Gland, the Olfactory Duct, and a Brain Tumor, respectively. Finally, the tenth participant suffered from HGH Deficiency resulting from Brain Thrombosis.
More HGH Patient Information
Among the thirty patients, 28 of them had received Bio-Identical Hormone Deficiency Treatment in the past for their Pituitary Insufficiency. There were 24 male patients and 6 female patients in the study. Each female HGH Deficiency subject was taking Estrogen Replacement Therapy, with 4 of those 6 taking progesterone as well.
Sixteen of the patients were simultaneously suffering from Testosterone Deficiency, and were either replacing their Testosterone with Intramuscular Testosterone Injections, or Topical Testosterone Products.
Twenty-one patients were taking Thyroxine for Thyroid Deficiency and twenty-four were taking cortisone acetate or hydrocortisone for adrenal hormone deficiency. Finally, seven patients were taking desmopressin.
HGH Deficiency: Experimental vs. Control
Every patient in this Hypopituitarism Sleep Study had their own personal control with normal HGH Levels. Experimental Group Patients averaged around 72 micrograms per deciliter, whereas control patients had an average of 194 micrograms per deciliter. All experimental patients had normal levels of potassium, sodium, and glucose. Overall, patients had Thyroxine Levels which averaged 86% of normal.
Each patient was matched with a control based upon Body Mass Index, Age, and Gender. The results of this study indicate that Human Growth Hormone Deficiency is strongly associated with daytime fatigue, inhibited sleep quality, and too much high-intensity Slow Wave Sleep. Strangely enough, this increased level of Slow Wave Sleep is not normally associated with most sleeping disorders, which are the result of inhibited Slow Wave Sleep.
There are a number of mechanisms by which this abnormal sleeping condition could lead to issues with sleep health and quality. There is evidence that Growth Hormone-Releasing Hormone enhances Delta Activity, because in healthy brains, HGH and IGF-1 serve as a negative feedback mechanism to limit Human Growth Hormone Production. There is animal research which supports this theory.
How Did HGH Deficiency Effect the Sleeping Patterns of Younger Patients?
Researchers also hypothesize that the hormone imbalance caused by the overproduction of Growth Hormone-Releasing Hormone could cause the body to continue to release signals for Slow Wave Sleep even while awake, which could lead to issues with daytime tiredness. This is especially pronounced among the youngest patients, as those with elevated levels of Slow Wave Sleep were more tired during the day than their counterparts. Among the thirty participants, exhaustion was the single complaint most reported in Self-Reported Quality of Life Scales.
How Did HGH Deficiency Effect the Sleep of Older Patients?
Among older Hypopituitarism patients, the most significant issue appeared to be a lack of sufficient REM Sleep, which is strongly correlated with Human Growth Hormone Deficiency. Lack of REM-Sleep is associated with a number of medical issues, including issues with memory. In this study, older patients with Human Growth Hormone Deficiency were more likely than their control counterparts to suffer from memory issues. As the body of research continues to grow, it becomes increasingly clear that memory is strongly correlated with sufficient REM-Sleep in adult patients.
Another issue that Older Adult Hypopituitarism Patients experienced was that they slept less than their control counterparts, and also slept less soundly and experienced a higher level of sleep fragmentation. It is true that older men and women experience less REM sleep as they grow older, as well as shorter sleep, and more frequent rousing from sleep, but experimental patients experienced these sleep issues at a rate higher than their control peers, and HGH Deficiency appears to be a powerful mechanism which inhibits healthy sleep among these patients.
Older Adult HGH Deficiency patients simultaneously experienced Slow Wave Sleep of high intensity and long duration earlier in the sleep cycle, and had more issues staying asleep later in the sleep cycle. This is a strange issue, because enhanced Slow Wave Sleep is usually correlated with longer, steadier sleep.
Pituitary Insufficiency Vs. Combination Hypothalamic-Pituitary Insufficiency
So, for patients that only experienced pituitary issues with no hormone imbalance resulting from hypothalamic insufficiency, Slow Wave Sleep was longer, but didn't provide sleep benefits for other reasons. This was not the case for patients that were suffering from Hypothalamic issues in addition to Pituitary Insufficiency. Patients that had diminished GH-RH response had issues with Non-REM Sleep, not reaching a sufficient depth of sleep for optimal health. There is significant evidence from other studies that shows that GH-RH Deficiency is associated with an inability to sleep deeply.
For participants that were suffering from Pituitary issues in which Hypothalamic Insufficiency was not ruled out, the results were a mix between the two classes of Hormone Deficiency.
How Did this HGH Sleep Study Compare to Previous Studies?
Interestingly enough, the results of this study were different from another study released twenty years previously, which studied patients with Isolated Growth Hormone Deficiency. There are a number of reasons for this, however. In the older study, participants were controlled on age and sex, but not with regard to Body Mass Index.
There were other aspects which were insufficiently controlled as well. Patients were not monitored for how long they slept, nor when they went to sleep. The earlier study also allowed for naps, and patients were not limited in their activity in the previous study.
In this earlier study, patients slept much longer, ranging from 7:45 of sleep to 11:44 among the eight patients. Increased need for naps and longer periods of sleep are generally associated with fitful sleep which is not sufficiently deep. Because of these various differences, the results in the newer study were different.
Another older study found no significant difference between patients with Adult-Onset Human Growth Hormone Deficiency and otherwise healthy patients, but the patients were not matched to their controls with regard to sleeping habits, age, gender, and other characteristics, which led the study to be unable to register sleep differences between HGH Deficiency patients and healthy patients.
Could Other Hormone Deficiencies Have Impacted Sleep Quality?
Almost all of the patients in this Growth Hormone Deficiency Study received some form of Hormone Replacement Treatment, such as Estrogen, Testosterone, Thyroxine, Cortisone, or Hydrocortisone, although none of the patients were receiving Growth Hormone Therapy.
There is no way to rule out that any of these treatments or other underlying hormone deficiencies could have an impact on their sleeping patterns and habits as well. In spite of this, the fact that older patients experienced greater issues with sleep than their younger counterparts does provide strong evidence that HGH / GH-RH Deficiency do have a powerful impact on sleep quality.
HGH Study Conclusion
Based on the results of this study, there is strong evidence that Human Growth Hormone Deficiency impacts health in a number of ways related to sleep, including increased feelings of exhaustion and sleepiness during the day, caused by inhibited sleep quality during the night.
The mechanism by which Human Growth Hormone Deficiency impacts sleep quality depends on multiple variables, and the age of the patient and the cause of HGH Deficiency both seem to be very important signifiers.
How Does This Study Relate to Age-Related Hypopituitarism and Somatopause?
It's important to note that this study almost universally involved patients with damaged or otherwise non-functional Somatotrophs. Age-Related HGH Deficiency is most commonly the result of an underlying GH-RH Deficiency.
Patients in this study that were unable to produce sufficient GH-RH experienced issues with their ability to achieve deep sleep, which is in line with the experiences of patients that suffer from HGH Deficiency resulting from the aging process.
WHAT IS ADRENAL FATIGUE
Written by , Published on 21 June 2014
What is Adrenal Fatigue, and How Does It Impact Physical and Mental Health?
Adrenal Fatigue is a medical condition that occurs when the body's ability to produce adrenal hormones is suppressed, preventing the body from functioning optimally. The body has a limited ability to produce certain hormones over time, and if the body produces too much of certain hormones over an extended period of time, it can sometimes no longer meet the needs of the body.
What Causes Adrenal Fatigue?
Adrenal Fatigue has many causes, and most are related to any issue which chronically puts physiological stress upon the body. High levels of psychological stress can lead to Adrenal Fatigue, as well as constant stress over a long period of time. Adrenal Fatigue can also occur as a result of physical stress from a variety of sources, including pneumonia, bronchitis, the flu, and chronic infections. Respiratory System infections are more likely to lead to Adrenal Fatigue than other forms of infection.
Adrenal Fatigue Is Caused By Exhausted Adrenal Glands
The primary symptom of Adrenal Fatigue is the reduced function of the Adrenal Glands that does not see improvement, even with sufficient rest. Adrenal Fatigue is a complex condition that is associated with a number of different disorders. Think of it as a symptom of other issues that are causing problems for the body or mind.
Adrenal Fatigue often goes undiagnosed, and people often mistake the symptoms of Adrenal Fatigue for psychological symptoms such as mild depression, exhaustion, or a general lack of well-being. People that have Adrenal Fatigue will often try to self-medicate their condition subconsciously by drinking a lot of cola or coffee or using stimulants to keep themselves energized enough to get by.
What Are Other Terms for Adrenal Fatigue?
Over the course of the 20th Century, Adrenal Fatigue has gone by a number on names, including Adrenal Apathy, Adrenal Neurasthenia, Neurasthenia, Sub-Clinical Hypoadrenia, and Non-Addison's Hypoadrenia. There are millions that suffer from Adrenal Fatigue in the United States and across the globe, but the condition is not distinctly considered a medical syndrome by most medical groups, and is simply considered a collection of connected symptoms.
How Can Adrenal Fatigue Impact My Life?
Adrenal Fatigue can significantly impact both your health and your general sense of well-being. Although the excess production of Adrenal Hormones such as Cortisol can have detrimental impacts on your health and wellness, so can too little of these hormones. Adrenal Hormones activate your body, getting you ready to seize the day, but they are not intended to remain at high levels 24/7.
Adrenal Hormone Production also spikes when you reach an impasse where your body activates the fight-or-flight response, helping you make split second decisions that could benefit you or even save your life. Obviously, nature never intended for Adrenal Hormones like Cortisol to remain at elevated levels for an extended period of time, and your Adrenal Glands eventually wear down and can lose their ability to produce enough of these hormones when they are actually needed.
In the case of severe Adrenal Fatigue, it can become difficult to even rouse yourself from bed for more than a brief period each and every day.
Adrenal Fatigue is a condition which can increase in severity over time, causing the symptoms to become more problematic. Every system of your body is impacted by diminished Adrenal Hormones, and this effects the core functions of your body. It can diminish your libido, strain your cardiovascular system, affect electrolyte and fluid balance, slow down protein synthesis and cause you to gain weight more quickly. It can also lead to diabetes and other conditions related to carbohydrate balance.
When your body doesn't produce enough Adrenal Hormones, your various systems and organs have to adapt to this biological change, and function at a sub-optimal level. Your body can function in a state of Adrenal Fatigue, but health will deteriorate in a number of different ways at the same time.
What Is the Underlying Cause of Adrenal Fatigue?
The definition of Adrenal Fatigue is quite simple, even though its causes are quite complex. Adrenal Fatigue simply means that the body is no longer producing enough Adrenal Hormones to keep up with the stress signaling of the body. If stressors are controlled, the body can boost Adrenal Function and regain Adrenal Hormone Balance, restoring the body to an enhanced state of Homeostasis.
The Adrenal Glands are responsible for the response to all forms of stress, whether they be psychological, emotional, or physical. When the Adrenal Glands activate, it leads to a cascade of hormonal changes which improve the body's ability to manage stress. Among the functions that are influenced by increased Adrenal Hormones are muscle tone, heart rate, immunity, and metabolism.
As we said, Cortisol and other Adrenal Hormones are activated under all forms of stress, whether you are defending yourself in a fight, mourning the loss of a loved one, fighting the flu, or just worried about your job. If the amount of stress that you experience is overwhelming, then you will start to tax your Adrenal System and will have physiological issues related to Adrenal Fatigue.
In a state of Adrenal Fatigue, you are still able to produce Adrenal Hormones, just not as much as your body needs to preserve normal function. Over-stimulation negatively impacts your Adrenal Health, and this leads to Hormone Imbalance which negatively impacts your health.
Adrenal Fatigue can be caused by chronic stress, or by single events that put a tremendous strain on your body or mind.
Who Is Most Likely to Experience Adrenal Fatigue?
Adrenal Fatigue is a condition that can affect anyone at any age. This condition is a stimulus-response at its core, and it doesn't matter how healthy you are, psychological stress and illness can put the weight of Adrenal Fatigue on your shoulders. Our Adrenal Glands have a limited capacity at any age or in any health state.
Although Adrenal Fatigue can happen to anyone, there are a number of environmental factors that can increase the risk of Adrenal Fatigue, including:
How Prevalent is Adrenal Fatigue?
Because Adrenal Fatigue isn't clinically recognized as a unique disorder, and is usually lumped in with other medical conditions, there is not sufficient data to say exactly how many people today suffer from the condition, although it can safely be considered to be at least somewhat common, if not more so.
In the late 1960s, a physician named Dr. John Tinterra was an Adrenal Specialist who was clinically active in the treatment of diminished Adrenal Function. He explained that, in the late 1960s, more than one in seven people were struggling with severe Adrenal Fatigue, although a much greater number of people were dealing with at least minor issues related to Inhibited Cortisol Production.
How Do I Know If I am Suffering From Adrenal Fatigue?
There are a number of symptoms associated with Adrenal Fatigue. Because Adrenal Fatigue is a complex disorder, it is the collection of symptoms which indicates the condition, rather than any particular, single symptom. Answer the following questions:
Do you feel exhausted with no clear cause?
Is it hard for you to rouse yourself from bed, even when you got adequate sleep the night before?
Do you have trouble recovering from illness or stress?
Do you frequently crave sweets and salty foods?
Do your energy levels peak during the late evening?
If you answered Yes to more than one of these questions, there is a significant chance that you may be suffering from Adrenal Fatigue, and you could greatly benefit from seeing a qualified, licensed medical professional regarding your health and hormone balance.
What Are Some Medical Conditions Commonly Related to Adrenal Fatigue?
Any medical issue that causes high levels of physiological stress can lead to Adrenal Fatigue. Patients experiencing chronic medical issues such as cancer or arthritis are particularly susceptible to depleted function of the Adrenal Glands. If you are suffering from a chronic medical condition, and you find it very difficult to get up and about, there is a very high likelihood that Adrenal Fatigue is affecting your energy levels.
There are also medications that can suppress adrenal activity, such as corticosteroids. Corticosteroids are synthetic hormones which imitate the function of the Adrenal Hormones, and the body will produce less of its own Cortisol and other hormones as a direct result. They are generally prescribed when the body is not producing sufficient Adrenal Response, but once treatment has been suspended, it can lead to symptoms of Adrenal Fatigue.
Adrenal Fatigue and Human Growth Hormone
Adrenal Fatigue can lead to HGH Deficiency if left untreated. The body primarily produces Natural Human Growth Hormone during sleep and during intense physical activity. Because Adrenal Fatigue can sap the body of energy, it is no longer as simple of an endeavor to go out and get sufficient exercise. Also, Adrenal Fatigue has a tremendous impact on sleep quality, which often prevents sufferers from reaching the deep phases of sleep necessary to encourage sufficient HGH Production.
For Patients suffering from HGH Deficiency or Hypopituitarism, Injectable HGH can alleviate the effects of the condition and improve Adrenal Balance, improving overall health.
Adrenal Fatigue and Testosterone in Men
Adrenal Fatigue is associated with a number of symptoms that can contribute to Low Testosterone. Clinical research shows that men that experience Adrenal Fatigue are more likely to suffer from Testosterone Deficiency. This is because Cortisol and Testosterone are both steroid hormones, and are both built from the same ingredients. If the body has been producing high levels of Cortisol, then the body no longer has enough raw ingredients to produce the sufficient amount of Testosterone to meet the needs of the body.
Testosterone Deficiency exacerbates the symptoms of Adrenal Fatigue, and the opposite is also true. This can lead to drastic changes in metabolism which lead to weight gain and muscle atrophy, while making fatigue even more pronounced. This can also affect sexual ability and libido, diminishing a man's ability to engage in fruitful, productive sexual activity.
Andropause and Hypogonadism can also lead to Adrenal Fatigue, as the reduced natural production of Testosterone can increase the body's Adrenal System activity due to physiological stress and Hormone Imbalance, which can inhibit the normal and healthy function of the body. For men with Age-Related Low-T, Testosterone Replacement with Creams, Patches, and Injections can help patients restore normal Sex Hormone and Adrenal Balance.
THE FACTS ABOUT ACROMEGALY
Written by , Published on 21 June 2014
The Facts About Acromegaly
Acromegaly is a medical condition which is caused by the excessive release of Human Growth Hormone by the pituitary, or by a tumor. The pituitary gland is a very small gland that rests just behind the eyes underneath the brain. The pituitary gland is often referred to as the Master Gland, because of the various functions that the pituitary gland controls, including reproductive function, metabolism, and growth.
What Causes Acromegaly?
The vast majority of patients with Acromegaly experience the condition as a result of a benign tumor attached to the pituitary gland, which imitates the activity of the Somatotrophs which are responsible for the release of Natural Growth Hormone. Excess HGH production over the course of a long period of time causes the body to grow abnormally. It causes the bones and cartilage in the feet, hands, and face to grow abnormally long and thick. Pituitary tumors that cause acromegaly can also lead to migraines because of the increased pressure in the brain, or pressure on the optic nerve.
How Do Hormones Contribute to Acromegaly?
Acromegaly effects the production and activity of three particular hormones that are very important, and all related to the somatotrophs. These are the hormones which are primarily affected by acromegaly:
Human Growth Hormone - Normally, the human body produces HGH throughout the day, in short bursts known as pulses. The hormone is primarily released during deep sleep and during intense physical activity. When the body produces too much HGH, it impacts the growth of organs and systems all throughout the body, and can impact physical appearance.
Insulin-like Growth Factor-One - The release of this hormone is directly influenced by the release of Human Growth Hormone. HGH circulates through the body, and much of it is processed by the liver into IGF-1. IGF-1 remains active more constantly than Human Growth Hormone, and many symptoms of Acromegaly are caused by a simultaneous rise in these two hormones.
Somatostatins - These hormones play an important role in Growth Hormone and IGF-1 regulation. Under normal circumstances, the human body recognizes the influx of HGH and IGF-1 and the brain releases somatostatins in response to mitigate the release of HGH by the pituitary. Somatostatin Therapy plays an important role in the treatment of Acromegaly.
What are the Symptoms of Acromegaly?
Acromegaly is a complex disorder which affects both health and appearance. Many people don't realize that they are suffering from Acromegaly for many years, because the effects onset slowly, and can often be difficult to notice until the symptoms are already problematic. Often, acromegaly symptoms are written off simply as aging by the patient, and there are many conditions which can imitate some of the symptoms of the condition.
Acromegaly often doesn't become clearly noticeable for many years. It is important to understand that although there are many signs and symptoms, most patients only experience a small number of symptoms. Below are the symptoms that are associated with Acromegaly:
Vision Changes due to Tumor Growth
Increased Size of Internal Organs
Increased size of Feet, Hands, and Jaw
Joint Swelling and Pain
Acne, Increased Oil Production, Thicker Skin, and other Skin Issues
Carpal Tunnel Syndrome
How is Acromegaly Diagnosed?
There are a number of tests that can effectively diagnose and keep track of Acromegaly. The most effective blood test for Acromegaly is Growth Hormone Analysis. Normally, HGH Levels spike and remain in the blood stream for only a brief period of time, but in the case of Acromegaly, Growth Hormone Levels remain excessively high, or reach abnormally high spikes..
Natural HGH Secretions are dependent upon a number of different variables, including when the test is taken, age, and genetics, as well as the last time that you ate. The following are the main means by which Growth Hormone Levels are Tested:
Oral Glucose Tolerance Test - The easiest way to analyze Growth Hormone Levels through a single test is for the patient to fast for a single night and provide blood after drinking a specialized solution of glucose concentrate.
IGF-1 Testing - One can also test for Acromegaly by testing IGF-1, which is released directly as a response to Growth Hormone Secretion. IGF-1 is a byproduct of Acromegaly, and it is exceedingly rare that IGF-1 Levels do not increase to abnormally high levels as a result of Acromegaly. IGF-1 Levels can also be easily tested, because they don't spike like HGH Levels.
Acromegaly Imaging Tests for Tumor Identification
Once the case for Acromegaly has been established, the physician will generally recommend imaging scans in order to identify the tumor. This can be completed using a CT Scan or an MRI. These tests provide a high-resolution image of the brain which can be monitored for tumors or other abnormalities. These Imaging Scans are outpatient procedures that do not require any patient preparation.
Health Tests Performed After Acromegaly Diagnosis
After Acromegaly has been diagnosed via HGH/IGF-1 Levels and a visual confirmation on the tumor, there are other tests that will be necessary to assess the health of the patient. Patients will usually undergo vision testing, chest X-Ray, and ECG to monitor the extent to which Acromegaly has affected the health. None of these tests require a stay at a hospital, and none of these tests even necessarily require a trip to the hospital, though they may be performed at one.
The technicians and specialists that perform these tests will forward the results directly to your primary care physician, who will explain the results in detail and use all of the information available to inform you of your current condition and what steps can be taken to improve your health.
Why Is It Important to Control and Treat Acromegaly
Until the tumor is surgically or medically removed, the condition is chronic, but proper treatment can cancel out the health modulating effects of the tumor. Through proper treatment, you can improve your health significantly and significantly reduce the risks associated with the condition.
Most patients begin treatment almost immediately after they have received diagnosis, and your healthcare provider can take steps to control the various factors at play with regard to Acromegaly, including controlling IGF-1 Levels, HGH Levels, treating the symptoms of the disorder, and treating the tumor itself.
Medical Conditions Associated with Acromegaly
Part of effectively treating Acromegaly is being aware of the increased risk of a number of different disorders and treating them accordingly. These conditions include:
Take Control of Your Acromegaly Treatment to Maximize Health Outcomes
It's vitally important to maintain awareness of your Growth Hormone and Insulin-Like Growth Factor-One Levels in order to effectively treat your condition. Your physician will provide you with somatostatins and other medical treatments designed to treat your hyperpituitarism as well as the medical conditions related to the disorder.
Every day that you go untreated, your health becomes that much more at risk. If you get treatment quickly enough, you can even reverse or at least mitigate some of the symptoms, including Hypertension, Sleep Apnea, Fatigue, Joint Pain, Sweating, Cartilage Swelling, and Headache.
Acromegaly Treatment Options
The most effective way to treat Acromegaly is by taking steps to get rid of the tumor. There are also treatments that can reduce the activity of the tumor until you can get access to treatment that will eliminate it.
Surgery for Acromegaly - The most direct way to treat a Pituitary Somatotroph Tumor is through surgery. Because the pituitary is located beneath the brain, it is often possible to remove the tumor with minimal risk, and in doing so, return IGF-1 and Growth Hormone Levels to normal, as well as eliminate Intracranial Hypertension.
This can be achieved through a method known as transsphenoidal surgery. In this procedure, the surgeon enters the brain cavity through the upper lip or through the nose and removes the tumor without having to open the skull.
Acromegaly and Human Growth Hormone
Acromegaly is a Pituitary Condition
Even though HGH Abuse can lead to symptoms that are normally associated with Acromegaly, it is important to point out that Acromegaly is a specific medical disorder which is caused by a tumor on the pituitary gland, and although long term abuse of Human Growth Hormone can lead to symptoms similar to Acromegaly, the two conditions are unique to one another.
Can HGH Injection Therapy lead to Acromegaly?
No. The goal of Human Growth Hormone Injections is to restore optimal, youthful HGH and IGF-1 Levels in the blood stream, not to introduce more of the hormones than the body is capable of handling in a healthy way. Acromegaly-like symptoms are the result of a long-term flood of Human Growth Hormone, and cannot be triggered by Restorative Doses of HGH.
HGH Abuse and Overdose Does Not Lead to Acromegaly Symptoms for a Long Period of Time
Also, like the condition of Acromegaly itself, it can take years of excess HGH and IGF-1 Levels before it becomes physically apparent that the patient is suffering from such a condition, whether it is from the disease of Acromegaly or the decision to abuse Bio-Identical HGH.
If a patient does begin to show Acromegaly-like symptoms, such as joint stiffness, carpal tunnel syndrome, or increased soft tissue production, there is still time to mitigate or prevent long-term damage to physiological health by suspending Injectable Growth Hormone Abuse.
Famous People with Acromegaly
Today, Acromegaly is recognized more quickly than it was in the past, and treated more promptly, but over the last fifty years there have been a number of celebrities that are known for having Acomegaly, the most famous of which is Andre the Giant. Andre the Giant was 7 foot 4 inches and weighed as much as 520 pounds. He first reached celebrity status as a star of the World Wrestling Federation, and later had a notable acting career, starring in films such as The Princess Bride and Conan the Destroyer.
Although he was largely seen as a beloved character, he dealt with an immense amount of pain from his condition which led him to alcoholism. In spite of his propensity for drinking and his wrestling persona, he was widely regarded as an incredibly kind and gentle person.
Other Celebrities with Acromegaly:
WWE star Big Show, also known as Paul Randall Wight, Junior
UFC Fighter Antonio Silva
Richard Kiel, most famously known for his role as Jaws for the James Bond Franchise
Carel Struycken, who starred as Lurch in the Adams Family films
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