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THE FACTS ABOUT ACROMEGALY


Written by Dr. Welsh, Published on 21 June 2014

The Facts About Acromegaly

Acromegaly is a medical condition which is caused by the excessive release of Human Growth Hormone by the pituitary, or by a tumor. The pituitary gland is a very small gland that rests just behind the eyes underneath the brain. The pituitary gland is often referred to as the Master Gland, because of the various functions that the pituitary gland controls, including reproductive function, metabolism, and growth.

What Causes Acromegaly?

The vast majority of patients with Acromegaly experience the condition as a result of a benign tumor attached to the pituitary gland, which imitates the activity of the Somatotrophs which are responsible for the release of Natural Growth Hormone. Excess HGH production over the course of a long period of time causes the body to grow abnormally. It causes the bones and cartilage in the feet, hands, and face to grow abnormally long and thick. Pituitary tumors that cause acromegaly can also lead to migraines because of the increased pressure in the brain, or pressure on the optic nerve.

How Do Hormones Contribute to Acromegaly?

Acromegaly effects the production and activity of three particular hormones that are very important, and all related to the somatotrophs. These are the hormones which are primarily affected by acromegaly:

Human Growth Hormone - Normally, the human body produces HGH throughout the day, in short bursts known as pulses. The hormone is primarily released during deep sleep and during intense physical activity. When the body produces too much HGH, it impacts the growth of organs and systems all throughout the body, and can impact physical appearance.

Insulin-like Growth Factor-One - The release of this hormone is directly influenced by the release of Human Growth Hormone. HGH circulates through the body, and much of it is processed by the liver into IGF-1. IGF-1 remains active more constantly than Human Growth Hormone, and many symptoms of Acromegaly are caused by a simultaneous rise in these two hormones.

Somatostatins - These hormones play an important role in Growth Hormone and IGF-1 regulation. Under normal circumstances, the human body recognizes the influx of HGH and IGF-1 and the brain releases somatostatins in response to mitigate the release of HGH by the pituitary. Somatostatin Therapy plays an important role in the treatment of Acromegaly.

What are the Symptoms of Acromegaly?

Acromegaly is a complex disorder which affects both health and appearance. Many people don't realize that they are suffering from Acromegaly for many years, because the effects onset slowly, and can often be difficult to notice until the symptoms are already problematic. Often, acromegaly symptoms are written off simply as aging by the patient, and there are many conditions which can imitate some of the symptoms of the condition.

Acromegaly often doesn't become clearly noticeable for many years. It is important to understand that although there are many signs and symptoms, most patients only experience a small number of symptoms. Below are the symptoms that are associated with Acromegaly:

  • Sleep Apnea

  • Diabetes

  • Cardiovascular Issues

  • Hypertension

  • Vision Changes due to Tumor Growth

  • Migraines

  • Cartilage swelling

  • Increased Size of Internal Organs

  • Increased size of Feet, Hands, and Jaw

  • Joint Swelling and Pain

  • Sweating

  • Acne, Increased Oil Production, Thicker Skin, and other Skin Issues

  • Nasal Congestion

  • Goiter

  • Impotence

  • Menstrual Disruption

  • Skin Tags

  • Carpal Tunnel Syndrome

How is Acromegaly Diagnosed?

There are a number of tests that can effectively diagnose and keep track of Acromegaly. The most effective blood test for Acromegaly is Growth Hormone Analysis. Normally, HGH Levels spike and remain in the blood stream for only a brief period of time, but in the case of Acromegaly, Growth Hormone Levels remain excessively high, or reach abnormally high spikes..

Natural HGH Secretions are dependent upon a number of different variables, including when the test is taken, age, and genetics, as well as the last time that you ate. The following are the main means by which Growth Hormone Levels are Tested:

Oral Glucose Tolerance Test - The easiest way to analyze Growth Hormone Levels through a single test is for the patient to fast for a single night and provide blood after drinking a specialized solution of glucose concentrate.

IGF-1 Testing - One can also test for Acromegaly by testing IGF-1, which is released directly as a response to Growth Hormone Secretion. IGF-1 is a byproduct of Acromegaly, and it is exceedingly rare that IGF-1 Levels do not increase to abnormally high levels as a result of Acromegaly. IGF-1 Levels can also be easily tested, because they don't spike like HGH Levels.

Acromegaly Imaging Tests for Tumor Identification

Once the case for Acromegaly has been established, the physician will generally recommend imaging scans in order to identify the tumor. This can be completed using a CT Scan or an MRI. These tests provide a high-resolution image of the brain which can be monitored for tumors or other abnormalities. These Imaging Scans are outpatient procedures that do not require any patient preparation.

Health Tests Performed After Acromegaly Diagnosis

After Acromegaly has been diagnosed via HGH/IGF-1 Levels and a visual confirmation on the tumor, there are other tests that will be necessary to assess the health of the patient. Patients will usually undergo vision testing, chest X-Ray, and ECG to monitor the extent to which Acromegaly has affected the health. None of these tests require a stay at a hospital, and none of these tests even necessarily require a trip to the hospital, though they may be performed at one.

The technicians and specialists that perform these tests will forward the results directly to your primary care physician, who will explain the results in detail and use all of the information available to inform you of your current condition and what steps can be taken to improve your health.

Why Is It Important to Control and Treat Acromegaly

Until the tumor is surgically or medically removed, the condition is chronic, but proper treatment can cancel out the health modulating effects of the tumor. Through proper treatment, you can improve your health significantly and significantly reduce the risks associated with the condition.

Most patients begin treatment almost immediately after they have received diagnosis, and your healthcare provider can take steps to control the various factors at play with regard to Acromegaly, including controlling IGF-1 Levels, HGH Levels, treating the symptoms of the disorder, and treating the tumor itself.

Medical Conditions Associated with Acromegaly

Part of effectively treating Acromegaly is being aware of the increased risk of a number of different disorders and treating them accordingly. These conditions include:

  • Colon Cancer and Colon Polyps

  • Sleep Apnea

  • Diabetes

  • Cardiovascular Disease

  • Hypertension

Take Control of Your Acromegaly Treatment to Maximize Health Outcomes

It's vitally important to maintain awareness of your Growth Hormone and Insulin-Like Growth Factor-One Levels in order to effectively treat your condition. Your physician will provide you with somatostatins and other medical treatments designed to treat your hyperpituitarism as well as the medical conditions related to the disorder.

Every day that you go untreated, your health becomes that much more at risk. If you get treatment quickly enough, you can even reverse or at least mitigate some of the symptoms, including Hypertension, Sleep Apnea, Fatigue, Joint Pain, Sweating, Cartilage Swelling, and Headache.

Acromegaly Treatment Options

The most effective way to treat Acromegaly is by taking steps to get rid of the tumor. There are also treatments that can reduce the activity of the tumor until you can get access to treatment that will eliminate it.

  • Surgery for Acromegaly - The most direct way to treat a Pituitary Somatotroph Tumor is through surgery. Because the pituitary is located beneath the brain, it is often possible to remove the tumor with minimal risk, and in doing so, return IGF-1 and Growth Hormone Levels to normal, as well as eliminate Intracranial Hypertension.

This can be achieved through a method known as transsphenoidal surgery. In this procedure, the surgeon enters the brain cavity through the upper lip or through the nose and removes the tumor without having to open the skull.

  • Radiation Treatment for Acromegaly - This form of treatment is paired with surgery in the instance that the pituitary tumor is not removed completely, and prescription medications are not effectively eliminating the remains of the tumor.

  • Prescription Acromegaly Treatment - There are a number of medications that can suppress the Pituitary's ability to produce Human Growth Hormone before surgery, and also help eliminate any tumor remnants that are not fully eliminated through surgery.

Acromegaly and Human Growth Hormone

Acromegaly is a Pituitary Condition

Even though HGH Abuse can lead to symptoms that are normally associated with Acromegaly, it is important to point out that Acromegaly is a specific medical disorder which is caused by a tumor on the pituitary gland, and although long term abuse of Human Growth Hormone can lead to symptoms similar to Acromegaly, the two conditions are unique to one another.

Can HGH Injection Therapy lead to Acromegaly?

No. The goal of Human Growth Hormone Injections is to restore optimal, youthful HGH and IGF-1 Levels in the blood stream, not to introduce more of the hormones than the body is capable of handling in a healthy way. Acromegaly-like symptoms are the result of a long-term flood of Human Growth Hormone, and cannot be triggered by Restorative Doses of HGH.

HGH Abuse and Overdose Does Not Lead to Acromegaly Symptoms for a Long Period of Time

Also, like the condition of Acromegaly itself, it can take years of excess HGH and IGF-1 Levels before it becomes physically apparent that the patient is suffering from such a condition, whether it is from the disease of Acromegaly or the decision to abuse Bio-Identical HGH.

If a patient does begin to show Acromegaly-like symptoms, such as joint stiffness, carpal tunnel syndrome, or increased soft tissue production, there is still time to mitigate or prevent long-term damage to physiological health by suspending Injectable Growth Hormone Abuse.

Famous People with Acromegaly

Today, Acromegaly is recognized more quickly than it was in the past, and treated more promptly, but over the last fifty years there have been a number of celebrities that are known for having Acomegaly, the most famous of which is Andre the Giant. Andre the Giant was 7 foot 4 inches and weighed as much as 520 pounds. He first reached celebrity status as a star of the World Wrestling Federation, and later had a notable acting career, starring in films such as The Princess Bride and Conan the Destroyer.

Although he was largely seen as a beloved character, he dealt with an immense amount of pain from his condition which led him to alcoholism. In spite of his propensity for drinking and his wrestling persona, he was widely regarded as an incredibly kind and gentle person.

Other Celebrities with Acromegaly:

  • WWE star Big Show, also known as Paul Randall Wight, Junior

  • UFC Fighter Antonio Silva

  • Richard Kiel, most famously known for his role as Jaws for the James Bond Franchise

  • Carel Struycken, who starred as Lurch in the Adams Family films


THE FACTS ABOUT PSORIASIS: SYMPTOMS AND CAUSES


Written by Dr. Welsh, Published on 21 June 2014

The Facts About Psoriasis

What Is Psoriasis?

Psoriasis is a medical condition that impacts around three percent of people in the United States. There are over five million men and women with psoriasis across the nation. Psoriasis is characterized by inflammation and scaling of the skin, and is mainly seen in adult patients, though psoriasis can also become an issue during childhood and adolescence. There is no gender divide with this condition, as both women and men are equally likely to experience the condition.

How Does Psoriasis Impact Skin Health?

The mechanism which causes scaling and inflammation is that new skin cells, which normally mature beneath the skin and rise to the surface, move to the surface before they have sufficiently developed. It normally takes a newborn skin cell around thirty days to reach the top layer of the skin, but in the case of Psoriasis, this process of turnover can take place in just a matter of days.

What Are the Symptoms of Psoriasis?

In the most common form of the condition, Psoriasis leads to high levels of inflammation, and the skin becomes red and topped with scales. The areas where scaling develops are called plaques, and they can lead to soreness and severe itching. Common areas where Psoriasis appears on the body are the soles of the feet, palms, face, lower back, scalp, knees, and elbows, although these patches can appear anywhere on the body.

Other areas where Psoriasis can appear are inside the mouth, on the genitals, and underneath the toenails and fingernails. If Psoriasis occurs on the joints, it can lead the inflamed area to become cracked and this can lead to bleeding. The psoriasis can also inflame the joints, which leads to arthritis symptoms. If this occurs, it is referred to as Psoriatic Arthritis.

How Can Psoriasis Negatively Impact Quality of Life?

People that have Psoriasis can experience life-altering issues resulting from the pain and itching associated with Psoriasis. Also, Psoriasis can limit movement in some cases, leading to limited disability.

Some patients experience severe pain and itching, which prevents them from living and appreciating their day to day life, causing sleep to be restless, making bathing a painful chore, and even making walking difficult. Patients that have Psoriasis Plaques on the feet and hands can have issues with any activity that involves those body parts, and they may not be able to participate in some sports or even have jobs in some careers. This can even inhibit their ability to care for their loved ones.

In order to mitigate the symptoms of Psoriasis, it can require frequent trips to the doctor, and the cost to treat the medical disorder is very high, as a result of the chronic nature of the condition. Psoriasis also impacts self-perception, because they are embarrassed about the way they look as a result of their condition. This can lead them to become withdrawn, or make it harder for them to enter romantic relationships. These issues can lead to social isolation, depression, and other psychological issues related to their poor self-image.

What Causes Psoriasis?

Psoriasis is a medical condition that results from an overactive immune system, and it is related to the body's production of T-Cells. T-Cells are powerful immune cells which fight disease and infection. When a person has Psoriasis, the body activates T-Cells for no reason and this causes a cascade of immune response which both causes immature skin cells to rise prematurely while also causing high levels of inflammation.

There is a genetic component to Psoriasis, and scientists have been able to link particular genes to the condition, based upon their study of certain family lines which are heavily impacted by the condition. Not all patients with Psoriasis have a family history, however.

What Causes Psoriasis Skin Flare-Ups?

Most people with psoriasis experience periods where their skin health becomes more problematic. These periods are known as flares. Psoriasis will temporarily become much worse, before recovering somewhat. There are a number of issues that can cause these flares to occur, including weather changes that lead to drier skin, stress, and infection.

There are also some medications that can exacerbate Psoriasis, including lithium and blood pressure medications known as Beta-Blockers. Finally, Psoriasis is more likely to flare up in areas of the skin that have experienced damage or irritation from issues such as infection, sunburn, scratches and lesions.

How Do Doctors Diagnose Psoriasis

Sometimes, Psoriasis can be problematic to diagnose, because it shares symptoms with a number of other skin conditions, such as Sebhoerric Dermatitis. The best way to clinically diagnose Psoriasis is by taking a small patch of the inflamed skin and looking at it through a microscope.

What Are the Types of Psoriasis?

There a number of kinds of Psoriasis. Below is a partial list:

  • Plaque Psoriasis - Characterized by inflamed, red skin covered in shiny scales.

  • Guttate Psoriasis - Characterized by small, round areas of inflamed skin on the scalp, limbs, and trunk. This form of the disease is commonly a reaction to strep throat or other infections of the upper respiratory system.

  • Pustular Psoriasis - Characterized by the formation of blisters which are not the result of infection. These blisters are filled with puss, and can be caused by stress, infections, medicines, and contact with particular chemicals.

  • Inverse Psoriasis - Characterized by inflamed areas along skin folds, such as the armpits, beneath the breasts, or around the genitals. Sweating and friction can exacerbate this form of Psoriasis.

  • Erythrodermic Psoriasis - Rapid and widespread appearance of Psoriasis that is commonly caused by corticosteroid medicines or significant sunburn. This form of Psoriasis can also occur as an extension of other forms of Psoriasis which are not effectively controlled. This is the most severe form of the condition, and requires an immediate visit to a medical professional.

What is Psoriatic Arthritis?

Psoriatic Arthritis is a medical condition that is related to and caused by Psoriasis, itself. In this case, Psoriasis penetrates into the skin and causes lesions and inflammation of the joints. Patients can experience both forms of Psoriasis simultaneously, or either alone at any particular time.

How Can Psoriasis Be Effectively Treated?

There are a number of methods that physicians use to mitigate the symptoms of Psoriasis, dependent upon the specific characteristics of the disease, including the locations of inflammation, the form of psoriasis, the surface area of inflammation, the severity of the psoriasis, and the way that the patient has responded to previous treatment.

The following are some common means by which Psoriasis can be treated:

  • Injectable and Oral Psoriasis Medication

  • Phototherapy via Light Exposure

  • Topical Medications

Like any medication, the treatments listed above can lead to side-effects, some minor, some more significant. Always talk to your physician and pharmacist about potential side-effects so you can be armed with the knowledge to recognize them.

There are some issues that make Psoriasis hard to treat. For one, the body can develop a resistance to certain forms of treatment, limiting their effectiveness over time. This is especially true of corticosteroids delivered topically.

Second, every patient responds differently to treatment, and the same medication or therapy may be highly effective for one patient while producing no benefit in a second patient. As a result of this, physicians often switch from therapy to therapy until they find one that works effectively with few or no side effects.


TYPES OF PSORIASIS TREATMENT


Written by Dr. Welsh, Published on 21 June 2014

Topical Psoriasis Treatment

These forms of therapy are delivered as creams, gels, or ointments directly onto the skin. There are a number of Topical Psoriasis Medications, including Anthralin, Coal Tar, Retinoids, Vitamin D3, and Corticosteroids, and all are effective for some patients.

For patients that are simply seeking respite from the itching or pain associated with therapy, there are lubricants and bath solutions that can reduce the severity of these symptoms, but most are not very strong and must be used in combination with more potent treatments.

Topical Corticosteroids for Psoriasis - These are some of the most common forms of Psoriasis Therapy. They work by slowing down the rate at which skin cells turnover, and they also ease inflammation and reduce the activity of the immune system.

Generally, Topical Corticosteroids are quick solutions that are used to treat ongoing outbreaks of inflammation, because dependence and overuse of these treatments can lead to issues such as resistance, internal complications, and weakening of the skin.

Synthetic Vitamin D for Psoriasis - This includes any medication or supplement which imitates the function of Vitamin D. These supplements can reduce the severity of Psoriasis by slowing down the rate at which the skin cells rise. Taking too much Vitamin D can cause problems, because Long Term Vitamin D Overdose leads to an overabundance of calcium.

Vitamin A Retinoids for Psoriasis - Retinoid Ointments deliver Vitamin A to the skin. Women that are pregnant or could become pregnant must be careful, because, although these treatments are safe for adult patients, they can cause birth defects if the patient is pregnant.

Coal Tar Solution for Psoriasis - These treatments can be purchased both via prescription and over the counter, dependent upon the concentration of Coal Tar. Coal Tar is often an ingredient in shampoos designed to relieve inflammation and dandruff, and they can also be massaged into the skin or used in order to medicate bathwater. The main issues with Coal Tar are that the medication can stain clothing and skin, has a potent smell, and can lead to skin irritation or sensitivity to sunlight.

Anthralin for Psoriasis - This medication treats Psoriasis by limiting inflammation and the increase in skin cell division. Physicians can prescribe it as a paste, cream, or ointment, designed to be administered daily for a short period of time in order to treat inflamed skin. After Anthralin has been applied, it must be cleaned off the skin in order to protect the skin from irritation. A downside to the treatment is that it is highly discoloring, and effects the majority of surfaces, including the skin.

Salicylic Acid for Psoriasis - This treatment is available in a wide variety of topical products, from creams to shampoos, and mitigates scaling by encouraging flaking.

Bath Products for Psoriasis - There are a wide variety of lubricants and oils which can help mitigate itching and wash off scales, including Dead Sea salts, Epsom salts, oiled oatmeal, and Coal Tar.

Lubricants for Psoriasis - These treatments are applied topically over a regular basis in order to reduce the discomfort associated with Psoriasis. Greasy and thick lubricants are most effective, because they reduce itching and scaling by locking water in the skin.

Phototherapy for Psoriasis

Ultraviolet Light, although damaging in high quantities, can be a very effective treatment for patients that suffer from Psoriasis. UV light stimulates the production of Vitamin D3 by the skin, which is one way that Psoriasis complications can be reduced. This light can either come directly from the sun or via artificial sunlight.

It's important to either follow a physician's advice exactly or have the physician personally assist in Light Treatment so that symptoms do not become exacerbated by sunburn or other issues, and so that the patient can minimize risk of cancer and skin damage via UV Light.

How Does Sunlight Treat Psoriasis?

Sunlight is comprised of a wide range of bands of Ultraviolet Light. When the skin absorbs sunlight, the Ultraviolet Rays kill off the sensitive T-Cells that are active in inflamed areas, reducing the effects of the disease. This simultaneously reduces the rate at which scaling occurs and mitigates inflammation.

Phototherapy with UVB Light for Psoriasis - Another method to treat and control Psoriasis is via UVB light. These are rays which are produced by sunlight or artificial sunlight which are absorbed into the deeper layers of the skin. UVB light can be an effective means to reduce the appearance and severity of moderate or mild Psoriasis. This is often the first course of action by many physicians, because it bypasses any form of medication.

Another form of UVB Treatment, known as Broadband UVB, is an alternative which is sometimes used to treat inflammation that is resisting normal creams and ointments, and it can also be used for general treatment of widespread or relatively minor Psoriasis. These treatments are provided via a box or panel that emits light, and in some cases, the patient may be approved to use one of these UVB emitters at home with a physicians permission and guidance.

There is also a third form of UVB Therapy for Psoriasis known as Narrowband UVB. This form of treatment specifically delivers the range of light that has been found to be most effective at treating Psoriasis. This form of treatment is considered to be more effective than Broadband UVB, but less effective than Psoralen with Ultraviolet A.

Narrow Band UVB is often used as an intensive treatment, administered several times in a short time frame in order to most rapidly improve the skin. If this intensive therapy is effective, patients often only require occasional treatment in order to preserve the benefits provided by the initial treatment. The main risk of Narrowband UVB therapy is that it can lead to longer and more severe burns as compared to Broadband UVB Light Therapy.

Psoralen and UVA Phototherapy for Psoriasis - This is considered the most effective means of light therapy for Psoriasis. In this form of treatment, UVA exposure is combined with a Topical or Oral Medication known as Psoralen, which amplifies the benefits of UVA light. Psoralen amplifies the skin's sensitivity to UVA light, and because UVA Rays affect deeper layers of skin than UVB light, this combination provides the fastest form of Light Treatment for Psoriasis.

This form of therapy is prescribed 2-3 times per week, and is able to eliminate Psoriasis symptoms very quickly. The issue with this form of treatment is that it can lead to a number of temporary side-effects, including itching, burning, fatigue, headache, and nausea. It is paramount to keep eyes covered with specialized glasses during therapy as well.

Long Term UVA-Psoralen Treatment also comes with an enhanced risk of Squamous-Cell Skin Cancer, and may also increase the risk of Melanoma.

Systemic Treatment of Psoriasis

The worst cases of Psoriasis are often treated with injections or pills which circulate treatment throughout the entire body. This form of Psoriasis Therapy is known as Systemic Treatment.

Methotrexate Therapy for Psoriasis - This form of treatment functions like an internal dose of cyclosporin. When taken via injection or pill, this treatment reduces the activity of the immune system, thereby reducing the rate at which turnover of the skin cells occurs.

This treatment is not without risks, however, and the patient much be monitored intently by the prescribing physician, because Methotrexate can reduce the concentration of platelets, white blood cells, and red blood cells in the blood stream while also potentially leading to liver damage.

Because of these risks, physicians do not prescribe this treatment to patients that have a history of anemia and liver disease. Also, this treatment should never be used by women that are pregnant, because the treatment can lead to birth defects.

Retinoid Systemic Therapy for Psoriasis - These synthetic treatments simulate the function of Vitamin A, and can be effective in the case of severe psoriasis that is resistant to treatment. Like the oral form, this treatment can lead to birth defects if used by pregnant women.

Oral Cyclosporine for Psoriasis - This treatment comes in the form of a pill, and reduces the rate of skin cell turnover. This treatment is effective very quickly, but only works for as long as the medication is in the system. It is most effective for stemming rapid-onset Psoriasis in order to prevent hospitalization.

Cyclosporine does come with side effects, and can lead to hypertension or impaired renal function. As such, a physician should closely monitor therapy. Cyclosporine is also not suggested for patients with a history of skin cancer or an impaired immune system.

Biologic Treatment for Psoriasis - These medications are comprised of proteins that are produced by living cells in order to suppress the processes of the immune system which lead to inflammation and the rapid production of skin cells. These treatments are delivered via injection, and can be self-administered.

Like most other oral and injectable Psoriasis treatments, ongoing treatment must be monitored closely by a physician. These treatments do lead to an enhanced infection risk, and they can impact the ability of vaccines to function effectively. There is also some correlation between Biologics and other medical disorders such as lymphoma, cancer, blood diseases, and CNS Disorders. The link between Biologics and these conditions has not been fully established, and these medications are only intended for use by adults.

Combination Psoriasis Treatment

Because of the complexity of Psoriasis, physicians often prescribe multiple forms of treatment simultaneously. This can reduce the risk of side-effects from various therapies by reducing the dosage needed to provide effective therapy and relief.

Psoriasis Counseling and Group Therapy

Many patients with Psoriasis benefit from getting psychological attention in order to mitigate the social costs of Psoriasis and improve psychological quality of life. Patients that have self-image issues commonly find relief by talking about their problems with a counselor, or having a support group of men and women that are suffering from the same condition.

Ongoing Psoriasis Research

Because Psoriasis is such a complex and problematic condition, and because it affects so many people, there is a lot of medical research going on to help advance the science of Psoriasis Treatment. Ongoing areas of research include how to help Psoriasis sufferers experience healthier skin and any way that it may be possible to stop or suspend the condition.

In recent years, medical knowledge regarding the genetic factors behind Psoriasis are becoming quickly illuminated. Today, there are a number of genes that are classified as being implicated in some way in the formation of the medical condition. Genetics is only one piece of the puzzle, however, and there are a number of factors which cause the disease to appear independent or only partially dependent upon genetics.

What medical researchers do understand is that there are certain genes which increase the likelihood of the expression of the disease. In addition to understanding the genetic mechanism behind the disease, researchers are also looking to understand the mechanism behind the sensation of itching more completely so that the side-effect of itching can be treated more effectively.

Ever since researchers found out that T-Cells are the primary affective culprit of Psoriasis, increased time and resources are being spent studying state-of-the-art treatments that can effectively reduce skin reactions cause by immune system over-response. One of the most promising areas of research is in promoting treatments which either limit the activities of cytokines or block T-Cell response. Cytokines are a form of protein that is responsible for inflammation.

The ultimate goal of these medical researchers is to figure out a way to treat Auto-Immune Psoriasis without suppressing the activity of the rest of the Immune System. If researchers are able to accomplish this, the benefits could branch out to other Auto-Immune Disorders as well.

What Are the Health Risks Associated with Psoriasis?

Medical studies have shown that men and women with Psoriasis have a correlated increased risk of a number of conditions including diabetes, hypertension, obesity, and cardiovascular complications. These issues are more apparent in patients with more severe forms of Psoriasis.

Scientists are attempting to figure out the physiological mechanisms by which these medical conditions are potentially linked in order to be able to provide patients with greater comprehensive treatment as well as learn more about how the various systems of the human body interact with one another.


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Three sided solution: Testosterone + HCG + Arimidex

If your doctor only prescribes testosterone by itself, you will probably have a rough ride. The tendency is for you to feel great the first couple months, while you increase testosterone levels, followed by a slow deterioration, once your estrogen creeps up.

High estrogen negates a lot of the positives from testosterone therapy, resulting in the same symptoms of low testosterone you had in the first place!

The solution is to add a drug called Arimidex. It's called an aromatase inhibitor, which essentially blocks the conversion of testosterone to estrogen. It has the effect of increasing testosterone levels, while keeping your estrogen low.

Once you have your testosterone and estrogen solved, it's time to stop the next inevitable decline? Shrinking testicles.

This is where HCG (human chorionic gonadotropin) comes in. It prevents both infertility and testicle shrinkage. Your testicles shrink because your body thinks it doesn't need to make testosterone anymore.

For some, small testicles may seem like just a cosmetic problem. But HGC does more than increase testicle size, it also increases adrenal function, which can have positive effects on well-being, libido, and energy.





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