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TESTOSTERONE AND OTHER SEX HORMONES IMPACT ASTHMA RESPONSE DEPENDENT ON SEX


Written by Dr. Welsh, Article reviewed and edited by Dr. Fine M.D..
Published on 21 July 2020


Many conditions affect men and women differently. One of these conditions is asthma. It has long been known that pre-pubertal males tend to have more issues with asthma than females of the same age, but the underlying reasons why have not been so clear.

Recently, researchers from Johns Hopkins have explored the effects of Testosterone concerning asthma. It's critical to understand how men and women differ physiologically because it leads to different risks and different factors that impact potential treatment options.

While this study was conducted in mice, its results are hypothesized to be transferrable to humans. The research was published via the Journal of Immunology last October. While women are less likely to experience asthma than men in adulthood, Testosterone activated inflammation receptors in the lungs in response to exposure to an allergen known as ovalbumin. Obviously, these results give some mixed messages.

Asthma Risk Dependent on Age and Sex

Asthma is an interesting condition because its prevalence changes among males and females depending on age. Prior to puberty, boys are more liable to have issues with asthma than girls. After puberty, however, the situation changes. Then girls and women are more likely to have asthma. This is a clear example of how sex hormones lead to wellness-related sex differences. By exploring the mechanisms behind these differences, we can improve asthma diagnosis and treatment protocols.

A previous study investigated how Estrogen effected lung inflammation in mice. They found that Estrogen triggers inflammation. As we mentioned earlier, post-pubertal girls and women have a much higher incidence of asthma than men of the same age. This data led researchers to hypothesize that Testosterone would provide benefits against lung inflammation. For example, while still in experimental phases, male hormones have been prescribed as a successful treatment for women with asthma.

Mouse Testosterone Asthma Study

In order to learn more about how Testosterone impacts asthma, researchers needed mice that couldn't produce their own sex hormones. By using castrated mice, they could precisely control hormone levels using Testosterone Implants, which slowly and steadily release hormones.

Researchers also had to simulate asthmatic allergic reaction in the mice, because mice don't normally experience allergic asthma. Researchers aerosolized albumin to trigger a lung reaction similar to what humans experience when they have an asthma attack.

Testosterone and Lung Inflammation

Lung Inflammation is triggered by specific immune cells known as Alveolar Macrophages. These microscopic phagocytes absorb and break down debris in the lungs. They also trigger inflammatory activity, including the cascade of symptoms associated with an asthma attack. Researchers expected Testosterone to protect against lung inflammation in the mice.

What they discovered was more complicated. While Testosterone suppressed most markers of inflammation, it activated lung inflammation, specifically in Alveolar Macrophages. Researchers then bred male/female mice without Testosterone Receptors in their Alveolar Macrophages. Here, they discovered a critical sex-difference. Male mice had less inflammation when these receptors were deactivated. Female mice saw no such change. This means that in male mice, Testosterone is more intricately involved in how irritants trigger asthma response.

This provides evidence for why Testosterone can help women with asthma, but those results are sex-specific. This research highlights that a person's individual characteristics are very important to consider when deliberating upon treatment options.

In the future, research like this will likely lead to treatment options that differ for men and women. While an asthma attack looks the same in males and females, the mechanisms which trigger the attack clearly differ, which provides different opportunities for ideal treatment. Antihistamines and Steroids are the go-to treatment for asthma, but males with severe asthma may benefit more from an alternative form of therapy.


MARK CUBAN ADVOCATES FOR HGH AS A REHAB AND RECOVERY TOOL


Written by Dr. Welsh, Article reviewed and edited by Dr. Fine M.D..
Published on 21 June 2020

Professional sports is big business. Team owners are interested in protecting their assets and providing for the best chance for their athletes to succeed. In the past, there have been widespread issues with players abusing Performance Enhancing Drugs to maximize results. Many drugs have been used illicitly for these purposes, including Steroids, Testosterone, and Human Growth Hormone

HGH and Other PEDs Likely Offer Critical Benefits

As we learn more about the vast benefits of these Hormone Therapy Treatments, it becomes incredibly clear that PEDs are no longer a black-and-white issue, and there are nuances at play. If drugs like Human Growth Hormone are blanket-banned, it prevents athletes from the enormous benefits offered by these treatments when used as a mechanism for healing and rehabilitation.

Mark Cuban, the owner of the Dallas Mavericks, is one of the central voices advocating for a revaluation of the manner in which we think about treatments long associated with Performance Enhancement. As we learn more about how Growth Hormone works, it becomes clear that HGH Injection Therapy offers benefits that may be critical to protecting players from the wear-and-tear of a professional athletic career.

Mark Cuban's Michigan State HGH Study

Cuban was so intrigued by the potential benefits of Human Growth Hormone that he commissioned a study to reveal its potential. A recent study produced by researchers from the University of Michigan provides compelling evidence that HGH Treatments may facilitate improved recovery from ACL surgery, one of the most common major injuries that college/professional athletes experience.

In this study, patients were injected with Bio-Identical Human Growth Hormone as part of their Rehabilitation protocol. When compared to placebo, they found that athletes that were prescribed HGH had significantly stronger knee joints than participants that received a placebo. This change in strength was not due to a difference in muscle mass, but the strength of the joint itself.

Those that took Growth Hormone Shots had 29% stronger knee-extension capacity than their counterparts. It's hypothesized that knee strength rebounds more quickly and completely because HGH invigorates the process, which restores cartilage, allowing the joint to withstand greater tension.

Results of HGH ACL Research Spur Mark Cuban to Voice His Opinion

Mark Cuban took these results and was quick to advocate for further research. He is confident that HGH Therapy provides an opportunity for players to heal faster and get back to living their dreams. It's also critical to recognize that regular people and amateur athletes frequently experience these same injuries. Cuban understands that there is an innate difference in using HGH to heal and recover from injury and using it chronically to gain an unfair advantage versus competition. Both Mark Cuban and the researchers suggest adding a Therapeutic Use Exemption for the fair medical use of PEDs.

Human Growth Hormone has the potential to be a powerful tool in the arsenal of doctors, therapists, and personal trainers that help patients recover from injuries that interrupt the rhythm of day-to-day life. It's almost certain that HGH Injection Therapy will be used for a wider range of medical issues, to the benefit of patients across the country.


FOUR BEST WAYS TO BOOST HGH LEVELS


Written by Dr. Welsh, Article reviewed and edited by Dr. Fine M.D..
Published on 05 June 2020

Four Best Ways to Boost HGH Levels

Human Growth Hormone is critical to keeping body and mind operating at peak capacity. As we get older, it becomes more challenging to maintain healthy HGH Levels, and it's essential that we do what is possible to maintain Growth Hormone Levels to preserve optimal health and wellness.

HGH is of immense importance because it helps control cellular metabolism and mitigates many side-effects associated with premature aging, such as weight gain, loss of strength, fatigue, cognitive decline, and depression.

Diet and HGH Production

Human Growth Hormone works in countervail with Insulin to keep energy levels elevated. The body uses HGH as a tool to free up energy stored in fat cells. One way to boost Growth Hormone Levels is via Intermittent Fasting. Intermittent Fasting isn't about cutting calories; it's about timing meals to maximize fat burning and HGH Output. Men are generally recommended to fast for 16 hours, while women usually fast for 14 hours per day. Every body is unique, however. Foods that contain Serotonin or Melatonin are also good for HGH Production primarily because they can improve sleep quality. Foods high in Glutamine, such as yogurt, are also proven to boost HGH.

Exercise and Growth Hormone Production

If you're interested in amplifying your HGH production, exercise is one of the easiest ways to do so. The body responds most effectively to alternating bouts of arduous exercise and baseline activity. This is often referred to as High-Intensity Interval Training. This style of exercise maximizes HGH output and puts the perfect amount of strain on your body while not activating the production of high levels of stress hormones. By combining high-intensity aerobic training with weight-lifting, you can maximize the release of Growth Hormone due to exercise.

Sleep and HGH Levels

Any doctor will tell you that getting healthy rest is just as important as diet and exercise when it comes to staying healthy and feeling great. The body produces the majority of Human Growth Hormone while we are in deep sleep. The body produces HGH to help the body heal and recover from the wear and tear of day-to-day life. Getting restful sleep is important because the brain produces Growth Hormone at its peak during Stage-3 deep rest. Make it your personal goal to get 7-9 hours of uninterrupted sleep. Also, recognize that Insulin production is antagonistic to Growth Hormone, so try not to indulge your sweet tooth just before bed!

HGH Therapy to Normalize Growth Hormone Levels

While the advice above will be effective for most men and women concerned about maximizing Growth Hormone Production, smart lifestyle choices are not always enough to get the job done. As folks get older, they become more susceptible to Age-Related HGH Deficiency. This means that HGH Levels remain low for physiological reasons out of their control. Luckily, Bio-Identical HGH Injections are highly effective at correcting Adult-Onset Hypopituitarism. If you've been struggling with symptoms of Growth Hormone Deficiency, consider contacting a Licensed and Board-Certified Wellness Clinic to explore your medical options!


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Testosterone Therapy Benefits

Correctly performed testosterone therapy can be your ticket to health.

Three sided solution: Testosterone + HCG + Arimidex

If your doctor only prescribes testosterone by itself, you will probably have a rough ride. The tendency is for you to feel great the first couple months, while you increase testosterone levels, followed by a slow deterioration, once your estrogen creeps up.

High estrogen negates a lot of the positives from testosterone therapy, resulting in the same symptoms of low testosterone you had in the first place!

The solution is to add a drug called Arimidex. It's called an aromatase inhibitor, which essentially blocks the conversion of testosterone to estrogen. It has the effect of increasing testosterone levels, while keeping your estrogen low.

Once you have your testosterone and estrogen solved, it's time to stop the next inevitable decline? Shrinking testicles.

This is where HCG (human chorionic gonadotropin) comes in. It prevents both infertility and testicle shrinkage. Your testicles shrink because your body thinks it doesn't need to make testosterone anymore.

For some, small testicles may seem like just a cosmetic problem. But HGC does more than increase testicle size, it also increases adrenal function, which can have positive effects on well-being, libido, and energy.





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