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Written by Dr. Welsh, Article reviewed and edited by Dr. Fine M.D..
Published on 11 May 2021

Hormone balance can be a fickle thing to maintain, especially as you age, or as a woman, during and/or after menopause. Women are very sensitive to hormonal changes, mostly because so many hormones are involved in reproduction and the menstrual cycle. Menopause, aging and lifestyle tends to wreak havoc on the delicate balance of hormones in a woman’s body, however. Here are the signs and symptoms to look out for if you suspect hormone imbalance.

What are Hormones Again?

Hormones are chemicals that are produced by several different glands and tissues throughout the body, being part of the endocrine system. Hence why the study of hormones is called endocrinology. Hormones are chemical messengers that travel through the body to organs and cells to tell them what to do and when. Aren’t our bodies amazing?

Hormones regulate sexual function, appetite, body temperature, metabolism, sleep, mood and stress levels, heart rate and more. They are incredibly important and if even just one hormone becomes significantly lowered or raised out of its normal range, problems will most likely arise.

Signs of Hormone Imbalance in Women

Excess Weight Gain: Excessive weight gain is often triggered by hormone imbalance. It seems like the weight came on quick and is incredibly difficult to lose. As said before, hormones play a big role in metabolism, as well as the nervous and reproductive systems. All three of these are involved in maintaining a healthy weight.

The hormones mainly to blame are increased oestrogen, cortisol and insulin, as well as low levels of thyroxin. Throughout a woman’s menstrual cycle, oestrogen levels naturally increase and this can cause women to crave and eat more fatty or sugary junk food.

Increased levels of the stress hormone, cortisol, slows down metabolism. Consider incorporating meditation or a calming exercise, daily, to reduce cortisol levels. Lowering sugar intake also helps with this as well as regular exercise.

Hormonal acne: Many women experience skin breakouts right before and/or during their menstrual period. In fact, about 50% of women in their twenties experience hormonal acne, as well as 25% of women in their forties who are about to experience menopause.

It’s normal for these breakouts to go away once menstruation is over and hormone levels fluctuate back down, but women who have excess androgens may experience chronic hormonal acne. This includes whiteheads, cysts, blackheads or just general redness and inflammation.

Androgens are male hormones such as testosterone and these can make the skin produce extra oil which clogs pores, causing acne. In addition, high androgens may be caused by excess insulin (another hormone). To combat this, you may need hormonal contraceptive pills or anti-androgen pills. To soothe inflammation, corticosteroids can help temporarily. Weight loss can prevent insulin resistance.

Mood Swings: One of the most common (and make fun of) symptoms of PMS is moodiness. Menopausal and pregnant women are also known to experience moodiness. Mood changes include anger, sadness, depression, irritability and anxiety and are mostly caused by fluctuations in oestrogen levels. Oestrogen affects neurotransmitters such as dopamine, norepinephrine and serotonin.

Some doctors prescribe hormonal birth control pills to control moodiness in extreme cases. Relieve mood swings naturally by engaging in regular exercise, avoiding stimulants (caffeine, sugar), taking calcium supplements, getting enough sleep and eating smart.

Digestive Issues: Oestrogen imbalances commonly lead to frequent stomach upsets. The gastrointestinal tract actually has receptors for both oestrogen and progesterone. If either of these are out of balance, symptoms such as abdominal pain, constipation, bloating, nausea and diarrhea may result. This could be the reason why women experience IBS more than men as they are twice as likely to have it. It’s interesting to note that male hormones such as testosterone have been seen to have protective effects against IBS.

Hormonal birth control pills do not seem to relieve digestive issues resulting from hormone imbalance. Try taking magnesium supplements or eating magnesium-rich foods to relieve constipation and get your digestive tract running smoothly. The foods to eat are whole grains, sweet potatoes, leafy greens, bananas and fish. Try incorporating fermented foods in your diet as well as ingesting enough fiber.

Low Sex Drive: Low testosterone levels are to blame here. Testosterone actually plays a major role in the sex drives of women, not just men. One study showed that postmenopausal women who reported low libido had increased sexual desire after being given testosterone. They also reported more satisfying sexual experiences. It’s critical that testosterone is taken under the supervision of a doctor or endocrinologist because women do not need high doses of the hormone – unwanted side effects such as unwanted hair growth and other masculine traits may result.

Besides testosterone replacement therapy, other ways to increase your libido include maintaining a healthy diet and engaging in regular exercise.



The Standard


Written by Dr. Welsh, Article reviewed and edited by Dr. Fine M.D..
Published on 06 May 2021

Belly fat is stubborn and frustrating. Resculpting the body to get rid of body fat is not a simple and easy task, though it is certainly not impossible. One of the reasons why it is so hard to burn belly fat is that your body primarily uses the midsection as its storage unit for fat. Hormone Balance helps us avoid the buildup of belly fat. It's also true that, as we get older, we become more prone to hormone imbalance as levels of HGH and Testosterone fall into decline. In women, the changes associated with Menopause also contribute heavily to increased body fat. What it comes down to is that the older that you get, the harder that it becomes to stay lean. Body fat can become especially stubborn when folks reach their forties and fifties. This is the period when the decline of important hormones often becomes noticeable and problematic.

Sources of Hormone Imbalance Associated with Belly Fat

Hormone Imbalance is often multifaceted, and the accumulation of body fat is often the result of multiple sources of imbalance. The following are several hormones and how they are associated with belly fat: Testosterone – Testosterone is intimately associated with masculinity and male optimal function. Testosterone helps maintain muscle mass. The more lean muscle that you have, the higher your basal metabolism, which protects against body fat. Testosterone Levels decline when men get older, which reduces metabolism and muscle mass and makes it easier for belly fat to stick around.

Estrogen – Estrogen is most important for women but also plays a critical role in men's health (in small doses). Men produce Estrogen from body fat. The more fat accumulates, the more Estrogen that they will make. Unfortunately, Estrogen is also a limiting factor on Testosterone Production. This is one of several feedback loops associated with obesity. Belly Fat increases Estrogen, which Suppresses Testosterone. Lower Testosterone makes it easier to gain weight which further increases the influence of Estrogen.

Insulin – Insulin is the tool that the body uses to capture free glucose from the bloodstream and transport it to fat cells for storage. Insulin resistance leads to weight gain because the increased concentrations of Insulin in the bloodstream make it harder to free energy stored as body fat.

DHEA – DHEA is a precursor hormone produced by the Adrenal Glands, which is integral to the production of Estrogen and Testosterone. Healthy DHEA activity helps ward off belly fat by promoting healthy Sex Hormone Production and improving the body's responsiveness to Insulin.

Cortisol - Cortisol is the body's key stress hormone, associated with both physical and psychological stress. Cortisol initiates fight-or-flight response and stimulates activity. Cortisol is critical to health but also very prone to imbalance. Chronic Stress causes Cortisol Levels to skyrocket, depleting the building blocks that would normally be available to produce Testosterone and other hormones that are important to stave off body fat. Cortisol both increases appetite and increases Insulin, meaning that you eat more calories, and your body is more prone to storing them as fat.

Ghrelin – Ghrelin is the hormone most directly associated with the sensation of hunger. Ghrelin is responsible for increasing appetite, and high levels of Ghrelin also encourage you to both eat more and store more calories as fat. Crash diets significantly increase Ghrelin production, which contributes to the long-term failure of extreme diets. Ghrelin increases the production of HGH, which helps break energy free from body fat. Intermittent Fasting and other diets which allow for moderate Ghrelin activity are good for weight loss, but extreme diets are counterproductive.

Adiponectin – Adinopectin stimulates weight loss and the breakdown of body fat. Obesity reduces Adinopectin activity. Adiponectin Levels are adversely affected by high levels of Insulin, blood sugar, and body fat. The body's fat-burning power is directly correlated with healthy glucose/Insulin dynamics.


Written by Dr. Welsh, Article reviewed and edited by Dr. Fine M.D..
Published on 30 April 2021
Hormone Therapy is a highly effective means to treat various forms of cancer, especially Prostate Cancer and Breast Cancer. In spite of their effectiveness, however, these treatments come with their own long-term risks. The American Heart Association recently provided a statement regarding these risks in Circulation: Genomic and Precision Medicine. For example, HRT Regimens designed to treat Prostate/Breast Cancer also increase the chance of dangerous cardiovascular dangers such as stroke and heart attack. According to the American Heart Association, these risks can be greatly mitigated with sufficient awareness and preliminary evaluation. This report offers updated information regarding the complications associated with various forms of Hormone Therapy. The report is designed to help medical specialists treat cancer effectively while managing the downstream risks associated with Hormone Replacement Therapy.

Breast and Prostate Cancer Treatments Improving

Breast Cancer is the most common kind of cancer in the United States, accounting for 30.3% of cancers in women. Among males, prostate cancer is the most common, at 21.5% of all male cancer diagnoses. Aside from skin cancer, most common cancers are associated in some way with hormones. As cancer therapies become more advanced, fewer patients succumb to the cancer itself. In fact, among those patients under HRT Treatment for hormone-dependent cancer, cardiovascular disease is the leading mortality risk.

Common Treatments for Breast and Prostate Cancer

Three of the most common Endocrine Treatments for cancer are Selective Estrogen Receptor Modulators, Aromatase Inhibitors, and Androgen Deprivation Therapy: SERMs are designed to eliminate tumor development by preventing cancer cells from feeding off of Estrogen. These treatments allow Estrogen to act normally in other parts of the body like liver/bone tissue without acting on breast tissue. Two common SERMs are ralloxifene and tamoxifen. Aromatase Inhibitors suppress the production of Estrogen and are commonly prescribed to women after menopause, especially high-risk patients. Letrozole, anastrozole, and exemestane are prominent examples of Aromatase Inhibitors. Androgen Deprivation Therapy refers to treatments designed to treat prostate cancer by cutting off access to the fuel source of Testosterone. This category is more broad. Some prescriptions block Testosterone from Prostate Cancer Cells (and prostate cells themselves). Another option includes medications that suppress the hypothalamic/pituitary activity which triggers Testosterone production.

Cardiovascular Complications Associated with Cancer Treatment

Unfortunately, all of the treatments above can have negative consequences for the cardiovascular system. For example, Aromatase Inhibitors are known to increase heart attack and stroke risk, and Tamoxifen can lead to blood clots. Because cancers can become resistant to certain treatments, sometimes patients have to change therapies for best results against the cancer. Unfortunately, while this improves cancer outcomes, it also further increases the odds of cardiovascular problems, including blood clots, arrhythmia, and high blood pressure. In men, Androgen Deprivation Therapy causes them to experience the full gamut of issues associated with Low-T, including impaired glucose metabolism, increased body fat, and heightened triglyceride/cholesterol levels. For all of the above treatments, the longer a patient is on the regimen, the greater the risks associated with the therapy. Researchers are investigating exactly how duration impacts risks. HRT Therapy for Cancer was riskiest for patients diagnosed with heart disease and those with multiple risk factors (including history of stroke/heart disease, smoking, high cholesterol, obesity, and high blood pressure). The American Heart Association published this report to help doctors and patients understand the risks associated with Prostate/Breast Cancer Treatment and the cardiovascular precautions that should be taken to maximize outcomes for patients. In the near future, there will hopefully be official guidelines to help doctors navigate the heart risks associated with HRT-Based Cancer treatment. Any patient that could benefit from Hormone Therapy for Cancer should first be directed to a cardiologist for testing and consultation.

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