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A MEDICAL DOCTOR TRIES HUMAN GROWTH HORMONE IN 1992


Written by Dr. Welsh, Article reviewed and edited by Dr. Fine M.D..
Published on 10 October 2018

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Dr. Edmund Chein :: Anti-Aging Specialist

One of the most important historical research studies regarding the safety and efficacy of Human Growth Hormone Replacement Therapy is the result of one individual Doctor Edmund Chein. Dr. Chein began his career trained as a health improvement specialist. In 1992 he was 42 years old and he felt that he was steadily declining as a human being. He was gaining weight more quickly than he had in his entire life and he was developing a growing pot belly. Talking to his own health physician, he learned that his own physical health was in danger. His cholesterol levels were abnormally high and his triglyceride levels were much higher than they should have been as well.

Poor Health Decisions and Natural Aging Put Longevity at Risk

Both he and his doctor knew that if he kept treading down the path he was currently taking his quality of life would quickly deteriorate. He knew that he had to change his life when he began experiencing chest pains. Part of him felt like he was too young to be at risk for a heart attack, but as a doctor, he knew that was not the case. His heart troubles led him to a cardiologist, who informed him that he was in grave dangerhis coronary artery was significantly blocked by cholesterol plaques and if the plaque broke off he could easily experience a potentially fatal heart attack. At once, Chein was advised to take medicines in order to control his cholesterol level.

Chein Confident in Hormone Replacement Therapy Approach

Although Chein understood the logic behind such a path, he made the decision to try a much less orthodox approach. As a specialist in physical rehabilitation and medicine, Dr. Chein had utilized Hormone Replacement Therapy for individuals who suffered from unique hormone deficiencies. As a result of Hormone Replacement Treatments, the patients he observed experienced massive benefits to their overall health, with little or no side-effects. He had been intrigued by the Human Growth Hormone Research performed by Dr. Rudman two years earlier and pored over the results with zeal, keeping them nearly memorized in the back of his mind.

HGH Most Promising Form of Hormone Replacement Therapy

There was increasing evidence that other hormones such as DHEA and Melatonin had the ability to alleviate the effects of aging, but nothing seemed to compete with the incredible promise of Human Growth Hormone. Dr. Rudman's study was one of the first of its kinda large scale analysis of the effects of Human Growth Hormone on Adult-HGH Deficiency. Dr. Chein was so confident in the potential of HGH Hormone Replacement Therapy that he made the decision to utilize the treatment himself.

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He was bold in his approachHe wanted to restore all of his primary hormone levels to those of a young man of twenty years old and measure the extent to which HGH Hormone Replacement Therapy could benefit he himself. In the back of his mind, he hoped that by restoring his proper hormone levels he could revert his physiology back to that of a 20 year old man. He felt that if he was physiologically optimized, that his cholesterol and triglyceride levels might normalize, preventing the need for other medications. If he alleviated the effects of aging with Human Growth Hormone, he felt that the medical threats of cardiovascular disease may actually go into remission, eradicating the chest pains that threatened his life.

Dr. Chein Begins Hormone Replacement Therapy

After he made the commitment to Hormone Replacement Therapy, he made an appointment with one of his local fellow physicians in order to diagnose a variety of different hormone levels within his body. After having his blood drawn and professionally tested, he learned that he suffered from multiple hormonal deficiencies, the most severe of which were Testosterone, Human Growth Hormone, DHEA, and Thyroid Hormone.

HGH Hormone Replacement Therapy Works

After having his deficiency diagnosed, he made the decision to restore his levels of these vital hormones to a level which would be normal for a healthy twenty year old, twenty two years younger than himself. Within the next 6 months, his health began to change dramatically. He no longer suffered from that anxiety-induced pain in his chest, and his triglyceride and cholesterol levels normalized, preventing his need for medications to preserve his cardiovascular system. In addition to this, and perhaps partially because, he also began to lose the weight that had accumulated around his paunch.

The doctor who prescribed Dr. Chein's medications was so impressed by the results, that he chose to utilize the hormone treatments as well. He also experienced the beneficial results of Hormone Replacement Therapy featuring Testosterone and Human Growth Hormone.

Hormone Replacement Therapy FAQ

What is DHEA?

DHEA is an intermediary form of sex hormone secreted by both males and females. DHEA is a precursor hormone which can be converted into both Testosterone and Estrogen by the human body. DHEA is primarily released by the adrenal glands. Users of DHEA claim that there are numerous potential benefits to the hormonal supplement. It is believed that DHEA can bolster the immune system, increase energy levels, improve cognition and memory, enhance muscle strength, and optimize adrenal gland function. DHEA may also have the ability to alleviate the symptoms of depression.

What Are the Symptoms of DHEA Deficiency?

There are a number of different potential symptoms associated with Low-DHEA Levels. These include loss of sex drive, anxiety, depression, persistent fatigue and exhaustion, dehydrated eyes, dry skin, brittle hair, sensitivity to audio stimuli, and changes in hair pattern as a result of hair thinning and hair loss.

What is Testosterone?

Testosterone is the primary male hormone, though it is produced in both the male and the female body. In males, Testosterone is known for inducing primary and secondary characteristics both before birth and during puberty. After puberty, Testosterone helps men retain their masculinity, in addition to preserving sexual and cognitive function. Testosterone is released by the Testes and Adrenal Gland in males, and in the Ovaries and Adrenal Gland in females. In both sexes, Testosterone is largely responsible for sexual desire, and Testosterone has other limited yet vital roles to play in female health.

What are the Symptoms of Testosterone Deficiency?

In Males In males, Testosterone Deficiency can hinder the body's ability to generate strong and well-defined muscles. In addition to this, Testosterone Deficiency is generally connected with excess levels of cortisol, which can cause high levels of stress and can lead to cardiovascular complications over time. Testosterone is vital for proper sexual function, and low levels of Testosterone can cause problems ranging from low libido to premature ejaculation and erectile dysfunction. Testosterone also plays a role in mood, and low testosterone levels can cause symptoms of dysthymia and depression.

In Females In women, Testosterone is tightly linked to female sex drive. When women do not have enough Testosterone, their desire for sex can plummet. Testosterone also plays an integral role in female sexual function, and without proper hormonal stimulation, a woman can find herself unprepared physically for sexual activity. In addition to this, there is evidence that Testosterone is linked to both bone health and mental health in female patients.

What is HGH?

Human Growth Hormone is the hormone responsible for general human development and maintenance. HGH is released at its highest levels during puberty, causing drastic changes in height during a period of only a few short years. HGH is released by both the male and female body, and although Testosterone and Estrogen are responsible for sexual differentiation, HGH is responsible for the physical growth of puberty. After puberty, our bodies secrete much less Human Growth Hormone, but it is still a vital hormone which preserves optimal function. After puberty, Human Growth Hormone primarily helps the body sustain and rebuild itself at the cellular level, effecting numerous, if not all, organ and cellular systems within the body.

What Are the Symptoms of HGH Deficiency?

There are a number of significant medical problems that can occur when HGH levels are deficient. Muscle mass starts to atrophy, leaving the muscles both aesthetically and functionally weaker. The skin becomes dehydrated and more prone to wrinkles, lines, and drooping. Over time, HGH Deficiency can lead to osteoporosis and general weakening of the bones. Human Growth Hormone has been linked with general well being, and HGH Deficiency can lead to symptoms of depression and anxiety.

What is Thyroid Hormone?

The Thyroid is the biggest endocrine gland in the human body. It is located in the neck just under the Adam's apple in males and the equivalent area in females. Thyroid Hormone is the primary hormone released by this gland. Thyroid Hormone is responsible for controlling hunger. A low level of Thyroid Hormone is diagnosed as Hypothyroidism. A high level of the hormone is diagnosed as Hyperthyroidism.

What are the Symptoms of Thyroid Hormone Deficiency?

Thyroid Hormone Deficiency prevents the body from feeling properly sated by meals, causing patients to become overweight, with a severity dependent upon the level of deficiency. Although weight gain is the primary symptom of Thyroid Hormone Deficiency, this disorder can also lead to decreased sex drive, memory loss, weakness, fatigue, constipation, and depression, among other medical issues. The human body constantly resides in a state of amplified hunger as a result of deficiency, causing the body to function as though hunger cessation is the most important goal, taxing other systems of the body as a result.

What is the Conscious Evolution Institute?

The purpose of this website is to provide a wide array of information regarding the viability of Hormone Treatments such as Human Growth Hormone HRT and Testosterone HRT as longevity medications meant to alleviate Age-Induced Hormone Deficiency. There are many paths to health, and our goal is to encourage you to become more proactive in preserving your own personal health, regardless of your current medical condition.

There are many roads to good health, whether it be through better diet, exercise, of Hormone Replacement Therapy. If you feel that you may be a candidate for Hormone Replacement Therapy, we encourage you to contact the Conscious Evolution Institute today. We are highly trained in rejuvenative therapies featuring Human Growth Hormone, Testosterone, and numerous other vital hormones and hormone derivatives. We promise to serve you promptly and with care. We look forward to hearing from you!


SOME GENERAL THOUGHTS ON TESTOSTERONE


Written by Dr. Welsh, Article reviewed and edited by Dr. Fine M.D..
Published on 29 September 2013

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Testosterone Trivia

Most Americans think about Testosterone and immediately connect it to either aggression or sexuality. Although these are two really huge aspects of Testosterone, it actually has a lot of different purposes in the human body.

Why is Testosterone linked to both sexuality and aggression?

Although there is no way to fully understand the link between these concepts, we can look back at human and evolutionary history in order to try to discern a fairly complete picture. Testosterone, Sex, and Aggression are likely linked because of the competitive nature of mating. Among the vast majority of animals, males are the suitors, and the female chooses a mate.

There are a lot of ways that male animals use Testosterone in order to try to get a leg up on their competition. This is the reason why male and female animals are usually physically different, rather than simply having different sexual organs. Secondary sex characteristics develop largely as a result of competition between males for the affection of a female.

Across a large segment of animals, especially mammals, this pattern of sexual competition results in displays of strength and dominance. As a result, male mammals tend to have larger muscles than their female counterparts, and display more aggressive behavior.

Although we like to think we've developed beyond this evolutionary process, it still plays a certain role in our lives whether we choose to recognize it or not.

Beyond the link between Testosterone, Aggression, and Sexual Competition, Testosterone plays a number of different roles in the health of both men and women. The rest of the article will feature some more information about Testosterone and Health that you may find very interesting.

For Women, Love Induces Testosterone Production

Women that have just entered a new relationship experience a flux of Testosterone Production. This increase in Testosterone Release is much higher than is experienced by either single women or women that have been in a relationship for an extended period of time. One study suggests that women release the highest levels of Testosterone in the initial three months of dating than any other time.

Interestingly enough, men experience the opposite effect. Men that have just entered a new relationship actually experience a reduction in Testosterone production. In a similar fashion, however, after less than a year, Testosterone Levels return to their normal state.

It makes sense, really. If a woman has made her decision on a man, it's in her best interest to compete for his affection. In the case of a man, after he has won a woman's affection, he no longer has to regularly compete with other men for her interest.

Testosterone Burns Body Fat

One of the most noticeable physical issues related to Testosterone Deficiency is that it causes a man to have trouble losing weight. Clinical research has shown that Testosterone Hormone Replacement Therapy has a positive effect on muscle-fat ratio, increasing metabolism and helping a man lose weight faster and more effectively.

The majority of studies corroborate the same evidence. Testosterone Treatments lead to a noticeable reduction in adipose fat. This is the most unhealthy form of fat that the body stores, as well as the most difficult to burn. Adipose fat pools around the midsection, especially around the hips, thighs, and stomach.

Testosterone Replacement Therapy should not be considered solely for it's capacity to induce weight-loss, however. There is a limited body of research regarding the long-term use of Testosterone Hormone Replacement Therapy, and should only be used by men that suffer from clinically diagnosed Low-T, that are experiencing symptoms such as Erectile Dysfunction, loss of bone density, muscle atrophy, or fatigue.

Testosterone is Linked to Financial Success

Making money even has a positive effect upon Testosterone Production. One study performed by researchers in Great Britain showed that financial traders experience significant Testosterone boosts solely on the quality of their financial performance that day. Men that experienced a successful day of trading earned a rush of Testosterone as a direct result.

The inverse was found to be true as well, when men produced naturally high levels of Testosterone in the mornings, they made more money on average than when their Testosterone Levels were lower. This is strong evidence that Testosterone can directly influence success.

Researchers also found a correlation between experience and Testosterone Production among these traders as well. Traders that had been at the job longer displayed a stronger correlation between both success and the rush of Testosterone and Elevated Testosterone Levels being a predictor for daily success.

It makes sense. Testosterone is not only linked to aggression, but assertiveness. In the frantic trading atmosphere, it makes perfect sense that assertiveness breeds success. Also, Trading is one of the most competitive atmospheres outside of athletic competition, and studies have repeatedly shown that asserting dominance over others through winning induces an incredible burst of Testosterone.

This creates a positive feedback loop, where those that are successful maintain higher levels of Testosterone than those that are not successful, leading to further success.

Testosterone Can Shrink your Testicles

Although Testosterone Hormone Replacement Therapy can lead to a number of highly beneficial effects, it does have the potential to lead to a few physical symptoms, the most noticeable is that the Testicles can shrink in size.

There is no health risk associated with this shrinkage, but it does have a negative effect upon fertility. Luckily, this effect is completely reversible, and after suspending therapy, the Testicles increase in size again, and sperm production increases as well. This does mean that men looking to conceive should not use Testosterone Replacement Therapy, however.

Another side-effect that occurs in some cases is that men can develop gynecomastia. Gynecomastia is a condition in which excess Testosterone is converted into Estrogen, which promotes an increase in breast size. This issue is also reversible, and can be relieved simply by adjusted the cumulative dose of Testosterone.

Although Testosterone Hormone Replacement Therapy for Testosterone Deficiency is a safe and effective medical treatment, Testosterone Abuse and Overdose can lead to the development of other symptoms. In women, these changes are exceptionally apparent. Testosterone abuse can cause women to start growing hair across their body, develop temporary male-pattern baldness, increase the size of the clitoris, and cause the voice to deepen. All of these effects can be resolved by suspending abuse, except in some cases the changes that occur to the voice are permanent.

Both men and women that Abuse Testosterone are much more likely to experience issues such as increased aggression, mood swings, acne, and red blood cell count.

For men and women using Testosterone Treatments under the guidance and authorization of a qualified medical professional, the risk of side-effects associated with abuse is negligible, and can be treated quickly and effectively in the case that they manifest.

Even Watching Sports Can Boost Testosterone

Testosterone and competition are intricately linked in males. As men prepare for any form of competition, they experience a sustained boost in Testosterone. This boost in Testosterone occurs regardless of the form of competition in question. Preparing for a high-stakes poker game leads to an increase in Endogenous Testosterone Production in the same way as training for the Olympics.

Men are just naturally wired in this way. It makes sense. Because of our complex and advanced nature, assertiveness and dominance can manifest themselves in countless ways. The brain considers mental competition just as important as physical competition, and adjusts hormone release accordingly.

An amazing side-effect of this pattern of Testosterone Production is that you don't even have to necessarily participate in an event in order to get a burst of Testosterone. Studies show that men that watch sports experience changes in Testosterone Levels in relationship to the success of their favorite teams.

In one particular study, researchers analyzed a group of male fans as they watched a World Cup soccer game between Italy and Brazil. Researchers discovered that after Italy lost, their fans experienced a drop in Testosterone Production, while the Brazil Fans were awarded with a boost of Testosterone. These changes in Testosterone for both parties mirror patterns of Testosterone Release associated with dominance and submission in other species.

Obesity and Fat Limit Testosterone Production

Testosterone Production is strongly correlated with body fat percentage. Men that are of a healthy weight produce more Testosterone than men that are obese, even after other factors have been controlled for.

There are two processes associated with this reduction in Testosterone Production. First, Fat cells have an unfortunate capacity to generate Estrogen. They do this by absorbing Testosterone and Testosterone Precursors, converting them into Estrogen and releasing them into the human body. For men that are obese, this can have a powerful impact on healthy Testosterone production, and can even lead to certain symptoms of feminization.

Obesity is also associated with an increase in general inflammation. Although there are many factors related to obesity which contribute to inflammation, the strongest is that obesity encourages the increased production of cortisol, which is produced from DHEA, a necessary precursor to Testosterone. In addition to this, stress causes an increase in fat storage, which further reduces the body's ability to produce and utilize Testosterone effectively.

Your Hands Explain Your Hormones

In both boys and men, the pointer on the right hand is almost always shorter than the ring finger on the same hand. This is not true to nearly the same extent for girls. This isn't a phenomenon that is specific to humans, however. In many animals (including rats) that have five fingers, this same difference between males and females of the species persists.

Researchers have discovered that among all species in which this phenomenon occurs, it clearly shows that the animal was exposed to elevated levels of Testosterone in utero. The more Testosterone that you receive before you are born, the greater that this difference between the lengths of the ring and pointer finger tend to be.

There is even evidence from a British study that male businessmen with the largest difference between the lengths of ring and pointer tended to be more profitable in business and remained in business longer than their counterparts.

Testosterone Can be Difficult to Measure Effectively

Testosterone Levels are dependent upon a number of different factors, and not all of them are static. For example, Testosterone Production peaks in the morning, meaning that some that display clinically low levels of Testosterone at night may have normal levels during the morning. For this reason, most physicians suggest that blood testing occur in the morning rather than the afternoon or evening.

Also, the thresholds for Testosterone Deficiency are not fully standardized, meaning that what qualifies as deficiency for one doctor may not necessarily hold true for another. The closest to a standard that we have in regard to American Testosterone Treatment is that any level below 300 nanograms per deciliter is generally considered low. The range for normal varies widely dependent upon age, health, and other factors. Normal Testosterone Production ranges from 300 ng/dl to 1000 ng/dl.

Because of this large level of variability, it is necessary to both display signs of Testosterone Deficiency while also displaying low or borderline levels of Testosterone Production. Many physicians also suggest that multiple blood samples may be used to maximize the value of the diagnosis.

The Benefits of Testosterone are Not Established for Healthy Men

It is believed that around three quarters of men over the age of sixty five have hormone levels that are perfectly normal. Although Testosterone Hormone Replacement Therapy can provide amazing and life-changing benefits for men that suffer from Testosterone Deficiency, there has not been sufficient study among healthy patients to recommend the use of Testosterone for men that do not display a physical need.

For men that are experiencing Testosterone Deficiency, Bio-Identical Testosterone can provide numerous benefits, including increased sex drive, sexual ability, and bone mineral density, while also promoting muscle and fat maintenance. It can even improve psychological health, alleviating mild to moderate depression while helping to counteract feeling of stress and anxiety.

Men with Certain Heart Conditions Should Avoid Testosterone Hormone Replacement

Testosterone Treatments are associated with a slightly elevated risk of heart conditions such as stroke and heart attack. This is because Testosterone treatments increase red blood cell counts as a result of therapy.

Testosterone Injections seem to increase RBC Counts more than other forms of therapy. Because of this risk of heart issues, men that are generally in very poor health should avoid Testosterone Replacement unless their doctor recommends it. It appears that the bulk of risk associated with Testosterone effects men that are already at high risk of heart attack or stroke.

Testosterone Replacement Does not Increase the Risk of Prostate Cancer

In the past, medical professionals and researchers hypothesized that Testosterone Replacement could contribute to an increased chance of prostate cancer. The main reason why physicians and scientists believed that Testosterone Therapy could cancer is because Testosterone Replacement often leads to an increase in a chemical known as PSA, or Prostate-Specific Antigen.

This chemical is released only by the prostate, and men with prostate cancer produce more of this chemical than healthy males. The last decade of research has shown that, although Testosterone boosts PSA production, this has no association with any enhanced cancer risk.

Testosterone Replacement Therapy can increase the size of the prostate in older males, however, leading to a condition known as Benign Prostate Hyperplasia. The only major symptom of this condition is that it becomes harder to urinate, and there are medical treatments which can alleviate the symptoms of the condition.

There is an ongoing debate among medical professionals in regard to whether prostate cancer should even be treated, because they become very common with age, but develop at an incredibly slow rate. At this point, men with prostate cancer should avoid Testosterone Replacement Therapy.

Sleep Apnea Causes Low-T

Males that experience sleep apnea have a significantly increased likelihood of experiencing Low-T. For men with Testosterone Deficiency and Sleep Apnea, it can be effective to treat both conditions simultaneously in order to promote greater health most effectively.

Although both conditions can be treated at the same time, it is important to realize that Testosterone Treatments can complicate Sleep Apnea if the sleep apnea remains untreated. This is why it is important for men to received a full physical and medical history before initiating Testosterone Replacement Therapy. By ruling out other medical conditions, your doctor can help confirm whether Bio-Identical Testosterone Treatments are the best source of action to improve your health.


B12: PEOPLE WHO HAD HIGHER VITAMIN B12 LEVELS WERE SIX TIMES LESS LIKELY TO EXPERIENCE BRAIN SHRINKAGE


Written by Dr. Welsh, Article reviewed and edited by Dr. Fine M.D..
Published on 30 September 2013

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The Importance of B12 for Energy and Health

Vitamin B12 is one of many important and vital nutrients used by the body to foster optimal health. Vitamin B12 is a vitamin which encourages peak function of blood cells while also maintaining the health of the nerves.

The vitamin also has another function central to human life: it is one of the necessary materials for the construction of DNA molecules, which store all of the data which contribute to human development. This nutrient also helps keep the body energized and strong, and Vitamin B12 Deficiency can lead to a condition known as Megaloblastic Anemia.

How Does the Body Absorb B12?

Vitamin B12 is drawn directly from the food that we eat. It is absorbed through a relatively simple process. The first step takes place within the stomach. The stomach contains powerful hydrochloric acid which has the ability to break down the foods we eat and render them into simpler parts.

When consumed as part of a meal, Vitamin B12 is connected to proteins in the food that we eat, and hydrochloric acid breaks the bonds which connect Vitamin B12 to the protein. After the Vitamin B12 Molecule has been freed, it then reacts with another molecule known as Intrinsic Factor.

Intrinsic Factor is a protein which bonds with B12, allowing the nutrient to be taken in by the body. There are some people that actually lack the ability to make Intrinsic Factor, which causes them to absorb very low levels of B12. This condition is known as Pernicious Anemia.

How Much B12 Does the Body Need?

The human body requires Vitamin B12 at all stages of life, but the requirements vary dependent upon age. Children need an amount which slowly grows from 0.4 micrograms in the first six months of life, to 1.8 micrograms per day at 13 years. From 14 years old through adulthood, the body has a relatively steady requirement for B12 which is around 2.4 micrograms.

Women that are pregnant need a little more in order to promote healthy fetal development, around 2.6 micrograms. Women that are breastfeeding need the highest levels, around 2.8 micrograms. This makes sense, because early in life, the child is completely dependent upon breast milk for nutrition, so the mother must increase her own production to compensate.

What Are the best Sources of Vitamin B12?

Vitamin B12 is one of a number of nutrients that are only available to human beings through either animal or synthetic sources. Below are a number of sources of Vitamin B12:

  • Milk Products

  • Eggs

  • Poultry

  • Meat

  • Fish

  • Some Yeast Products

  • Supplements

  • Fortified Cereals

  • Other Fortified Foods

  • Clams

  • Liver

The final two suggestions, Liver and Clams, contain the most significant levels of B12. B12 is processed by the liver in animals that cannot produce it naturally, and it is synthesized in herbivores that do have the capability to make their own Vitamin B12 from plant material. As a result, aside from clams, liver is the single best source for Vitamin B12.

What is Vitamin B12 Deficiency?

A deficiency of Vitamin B12 brings about a rather particular set of symptoms, among which are:

Physical Symptoms of B12 Deficiency

  • Weight Loss

  • Appetite Suppression

  • Constipation

  • Weakness

  • Fatigue

  • Megaloblastic Anemia

Neurological Symptoms of B12 Deficiency

  • Tingling and Numbness in the Feet and Hands

  • Soreness of the Tongue or Mouth

  • Cognitive Decline

  • Dementia

  • Confusion

  • Depression

  • Balance Issues

It should be noted right away that a deficiency in Vitamin B12 can cause neurological symptoms, even if the physical symptoms do not manifest themselves. Some of the neurological damage resulting from B12 Deficiency is also irreversible, so it is incredibly important to diagnose and treat Vitamin B12 Deficiency as soon as possible.

Although the overall need for B12 is lower for children than adults, severe issues can occur as a result of prolonged Vitamin B12 Deficiency early in life. B12 Deficiency can cause many problems for infant patients.

The Symptoms of Childhood B12 Deficiency include:

  • Megaloblastic Anemia

  • Slow Development

  • Disorders of Movement

  • General Failure to Thrive

If you notice any of these symptoms, it is important to make an appointment with a pediatrician as soon as possible. The symptoms of Vitamin B12 Deficiency share similarities to other developmental disorders, and it is important to get an appropriate diagnosis as soon as possible.

How is Vitamin B12 Deficiency Cured?

Generally, the way to resolve B12 Deficiency is through direct intervention with Injections of Vitamin B12. B12 Injections allow for maximum absorption, because B12 is delivered directly to the body, bypassing more limited digestive absorption. If an immediate injection is not deemed necessary, a physician may recommend taking Vitamin B12 Orally in high doses in order to resolve the Deficiency.

One study compared the effectiveness of Oral B12 versus B12 Injections. Researchers found that oral Vitamin B12 was able to replicate the effectiveness of injections over time. The optimal way to restore B12 through oral supplementation was to take high doses of B12 (2000 micrograms) every day initially, then cutting the dose in half. After cutting down to half doses, it was eventually possible to cut down to weekly, and finally monthly, doses, before simply allowing the patient to proactively make steps to maintain healthy levels of Vitamin B12.

Although both forms of supplementation are effective, the ability of the patient to absorb the nutrient through the digestive tract, and the severity of the deficiency will be the most significant factors which lead the physician to take the appropriate course of action.

How are B12 Shots Injected?

Like Testosterone Injections, B12 Injections are Delivered Intramuscularly.

How are Vitamin B12 and Folic Acid Connected?

Individuals that consume a high level of Folic Acid in their diet can make the dangerous symptoms of severe Vitamin B12 Deficiency less apparent. Folic acid has the ability to resolve Megaoloblastic Anemia without resolving the underlying neurological complications of the condition.

There are even studies which provide evidence that high levels of folate in the blood stream can eventually make anemia worse and amplify the neurological issues related to B12 Deficiency, increasing the risk of cognitive decline.

This combination of Folic Acid Overload and B12 Deficiency can lead to permanent nerve damage. Because of this significant risk, healthy men and women should take no more than 1,000 micrograms of Folic Acid per day.

Who is at Greatest Risk of B12 Deficiency?

There are a number of issues which can lead directly to Vitamin B12 Deficiency. These causes include:

  • Pernicious Anemia

  • Lack of B12 in the diet

  • Inability to appropriately absorb B12

  • Post-surgical inability to properly absorb Vitamin B12

Although these are the four leading causes of Vitamin B12 Deficiency, there are many cases in which the cause of B12 Deficiency is unclear.

Who is Most at Risk of B12 Deficiency?

Aging Adults

As men and women grow older, the odds of developing Vitamin B12 Deficiency grow. There is a condition known as Atrophic Gastritis, which causes the stomach to produce abnormally low levels of Hydrochloric Acid. As a direct result of this, B12 Absorption drops.

This condition affects ten to thirty percent of older men and women. This change in hydrochloric acid production can also change the composition of gut flora, leading to the formation of bacteria which consume Vitamin B12 to propagate, reducing the amount available to the body itself.

Because this disorder reduces the body's ability to break down food sources of Vitamin B12, it can be easily treated through direct supplementation. In addition to this, foods fortified with B12 are also a useful source, because the synthetic form of B12 present in most fortified foods is easier to absorb than natural B12 for these individuals.

Because of the risk of Atrophic Gastritis, physicians recommend getting B12 from either fortified foods or supplements after the age of fifty. It should also be noted that elderly men and women that have this disorder should intake more Vitamin B12 than Recommended Daily Values Suggest.

People with Pernicious Anemia

Pernicious Anemia is a medical issue which afflicts between one and two percent of adults over fifty. The main issue with regard to these patients is they either produce no or little Intrinsic Factor, which is necessary in order for the digestive system to properly absorb B12.

The most effective way to treat this medical condition is through the use of Vitamin B12 Injections. Injections bypass the need for Intrinsic Factor and supply usable Vitamin B12 directly to the body. It may also be possible for some patients to use high doses of oral B12 in lieu of Vitamin B12, because around one percent of orally ingested Vitamin B12 can be absorbed even without the agency of Intrinsic Factor.

People with General Gastrointestinal Problems

There are certain diseases of the small intestine and stomach which complicate Vitamin B12 Absorption, including Crohn's Disease and Celiac Disease. These complications can prevent patients from getting the Vitamin B12 that they need from a normal diet.

Because of this inherent deficiency, some individuals with diseases such as these can experience very subtly decreased cognitive ability as a direct result of childhood Vitamin B12 Deficiency. In addition to this, they can also eventually suffer from dementia or Megaloblastic Anemia. For this reason, it is undeniably important for anyone with gastrointestinal disorders to evaluate their B12 Levels on a regular basis as a preventative measure against these conditions.

People that Have Undergone Surgery of the Stomach or Small Intestine

Certain surgeries can impact the digestive system's ability to absorb healthy levels of Vitamin B12. Individuals that undergo gastric bypass surgery or other weight loss surgeries often find that their ability to absorb Vitamin B12 Decreases as a result of less Intrinsic Factor and Hydrochloric Acid release by the stomach.

Any surgery which removes part or all of the stomach also leads to this issue. This has particular effect upon the body's ability to absorb natural forms of B12. Removal of the end of the small intestine, known as the distal ileum, can also inhibit or stop B12 Absorption. Anyone that goes under the knife for gastrointestinal surgery of any kind should be regularly monitored for any nutritional complications.

Vegetarians

Vegans and vegetarians are at a high risk of developing B12 Deficiency if they are not conscientious about their diet. The only natural sources of B12 for human beings are derived from animal products, and, unless vegetarians look to supplemental sources of B12, it will be impossible to get the necessary Vitamin B12 for optimal health.

Vegetarians that still use milk products or eat eggs do not have this same levels of risk, and pescatarians can easily get the B12 they need from fish sources. Luckily for vegetarians, there are now a number of fortified sources of B12, the most common of which is contained within many breakfast cereals.

Lactating and Pregnant Vegetarians, as well as their Infants

During pregnancy, the fetus receives necessary Vitamin B12 through the placenta. After being born, B12 is received through the breast milk. If infants are breastfed by vegetarian mothers, they often receive abnormally low levels of B12, which can hinder their optimal development. If B12 Deficiency is not caught very early, it can cause very serious and potentially life-long problems.

American Dieticians very strongly suggest that both lacto-ovo vegetarians and vegans take ample supplemental B12 during pregnancy in order to ensure the health of the infant. They should also ask their doctors about providing their young children with B12 Supplements to eliminate all potential risk.

Connections Between Vitamin B12 Deficiency and Negative Cardiovascular Outcomes

Among first world countries, heart disease is usually the number one cause of death. In developing countries, the threat of Heart Disease continues to increase as other easily preventable causes of death are eliminated, and changes in diet and lifestyle promote increased odds of the condition. Some major risk factors of Heart Disease are:

  • Diabetes

  • Obesity

  • Low HDL Cholesterol

  • High LDL Cholesterol

  • Hypertension

  • High Homocysteine Levels

Vitamin B12 and Homocysteine

Homocysteine levels are strongly associated with Vitamin B12 Consumption. Homocysteine is an amino acid compound that is necessary for a healthy cardiovascular system, the problem is that a lot of individuals produce way too much of it.

Excessively high Homocysteine production causes a number of issues which reduce the function of the heart and increase the risk of heart complications. It encourages the formulation of clots, prevents proper vasodilation, and changes the muscular composition of veins and arteries. It also causes the breakdown of fat in the blood stream, releasing dangerous free radicals into the body.

Vitamin B6, Folate, and Vitamin B12 are vitally important in the metabolism of Homocysteine. In the result of B12 Deficiency, Homocysteine production can rise in a dangerous manner. Vitamin B12 Supplementation in combination with Folate Supplementation has been shown to have an ameliorative effect on Homocysteine Production, encouraging a reduced risk of stroke.

To this point, the evidence is incomplete in regard to whether providing B12 Supplementation improves other aspects of Cardiovascular Health in at-risk patients. This does not, however, diminish the importance of maintaining healthy B12 consumption throughout the lifespan, because, although Vitamin B12 may be limited in its ability to treat heart problems, proper use of B12 throughout the lifespan can help reduce the risk of developing these complications in the first place.

Vitamin B12 and the Brain

B12 May Protect the Brains of the Elderly

In a recent study conducted by scientists at Oxford, a strong correlation was found between the overall volume of the brain, and healthy Vitamin B12 consumption. In this study, researchers collected data from 107 participants. These participants ranged in age from sixty one to eighty seven. None of the subjects displayed any signs of cognitive decline or issues with memory. The median age of the subjects was seventy three, and 46% of the participants were men.

The scientists then proceeded to draw blood in order to assess the Vitamin B12 levels of each patient. Vitamin B12 is found in highest concentrations in milk, fish, and meat. In addition to blood testing, each subject also underwent annual MRI brain scans in order to visually assess the condition of the brain. They also received a yearly physical and memory evaluation.

Among the 107 men and women, none of them were found to have a Vitamin B12 Deficiency. Researchers took the data that they compiled from this study and compared it to studies of patients which suffered from Vitamin B12 Deficiency. They discovered that men and women with Vitamin B12 Deficiency were six times more likely to have smaller brain volumes than patients that had healthy levels of B12.

Although they were able to establish this link, the scientists were not able to provide evidence regarding the impact of brain size on cognitive impairment.

Maintaining Healthy Vitamin B12 Levels Helps Prevent Cognitive Issues Later in Life

The project leader, Anna Vogiatzoglou, explains that there are a lot of different factors which contribute to adverse changes in the condition of the brain, but her study shows that there is a powerful connection between Vitamin B12 and the preserving the size of our brains.

Although her study did not have the ability to establish psychological and cognitive changes related to changes in brain size with age, she hypothesizes that making sure that we get enough Vitamin B12 throughout our lives is a thoughtful and productive step in preserving proper and healthy brain function later in life. By taking this healthy and conscientious step, there is a significant chance that we can preserve our memory more effectively with age.

Although the study provides a positive link in regard to Vitamin B12 Levels and Brain Shrinkage, the study did not analyze the effect of Vitamin B12 Supplementation as a preventative treatment for elderly patients.

It appears that, like the connection between Cardiovascular Health and Vitamin B12, there is a limited ability for Vitamin B12 to be a treatment for conditions related to untreated Vitamin B12 Deficiency, but maintaining healthy Vitamin B12 Levels throughout the lifespan can help prevent significant issues later in life.

Does Excessive B12 Supplementation Lead to any Health Risks?

Vitamin B12 has an extremely low capacity for toxicity. Because of this, there is little to no risk of complications resulting from the over-consumption of the nutrient. Vitamin B12 is water-soluble, and nutrients of this type are generally absorbed by the body as needed, then released into the urine. Fat soluble Vitamins generally carry a certain risk of overdose (Vitamin A being one particular example).

Vitamin B12 Final Thoughts

As you can see, it is vitally important to make sure that your body gets a healthy dose of Vitamin B12. If you are conscientious, this is one of the best ways to preserve your cognitive health deep into old age.

There is really no reason to experience Vitamin B12 Deficiency, unless your body is beginning to have trouble processing the nutrient. If you have a feeling you aren't getting enough Vitamin B12 in your diet, we actively encourage you to seek out a supplement. There is absolutely no downside, and it can have a tremendously positive impact upon your cardiovascular system, neurological system and general energy levels.


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