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HGH Bone Skeleton Calcium and Mineral Structure

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Osteoporosis Guideline: Diagnosis and Treatment

We hear about the dangers of osteoporosis all of the time, but we rarely hear the disease explained. From a linguistic standpoint, Osteoporosis literally means porous bones. The disease is highly associated with an increased risk of bone breaks and fractures. As men and women (especially women) grow older, the risk for severe damage to the hips and spinal column can result. Hip fractures are one of the single most dangerous breaks that can occur to the human body, and these fractures are associated with a greatly increased risk of mortality.

Hip Fractures and Increased Mortality

A recent study released by the University of Pennsylvania Medical School shows that women who have recently experienced a hip fracture have over twice the mortality rate of female patients who did not. Patients who did not experience these fractures had an annual mortality rate of 8.4%, whereas those who experienced a hip fracture had a mortality rate of 16.9%. This mortality rate was adjusted to take into account confounding health factors and averaged for general bone density. Osteoporosis is one of the primary culprits which lead to bone fractures, and Human Growth Hormone has been shown to reduce the risk of these devastating breaks through HGH Injections.

How is Osteoporosis Diagnosed?

Osteoporosis is officially designated by the World Health Organization as a Mineral Bone Density which is greater than 2.5 Standard Deviations lower than the average bone density of young and healthy individuals of normal bone health.

The Three Forms of Osteoporosis

Primary Type 1 Osteoporosis:

Primary Type One Osteoporosis usually strikes in women after menopause. This form of osteoporosis occurs in females at a far greater rate than males. Women are diagnosed with Primary Type 1 Osteoporosis six times more often than males. This form of Osteoporosis develops slowly after menopause (or Andropause in men) and generally takes ten to fifteen years to become diagnosable.

Linked to Hypogonadism (Sexual Hormone Deficiency)

This type of osteoporosis is directly linked to sex hormone deficiency in both sexes. In women, Estrogen is vitally important to the proper maintenance of bone health. In males, proper Testosterone levels are equally as important. The reason why women are diagnosed far more often than their male counterparts is that Menopause represents a much more marked hormonal contrast than andropause.

What is Andropause?

Andropause is the male form of menopause. During the course of Andropause, Testosterone levels decline over time leading to a highly symptomatic form of Testosterone Hormone Deficiency. Testosterone levels start to decline around the age of thirty, and this decline produces more and more problems as Testosterone Levels in the body become increasingly meagre.

When does Andropause Lead to Osteoporosis?

Although men continue to produce Testosterone throughout the lifespan, by the time men reach their fifties and sixties, their bones start to become at risk for osteoporosis. A number of other symptoms of Testosterone Deficiency can start to appear much earlier, however. Muscle strength starts to deteriorate in the late thirties and early forties. Metabolism rates can drop significantly by the mid-thirties, leading to increased weight gain exacerbated by a sedentary lifestyle.

Why does Osteoporosis Take so Long to become Symptomatic?

The reason why bone health takes much longer to decline is because of the natural resiliency of the skeletal system. The bones have such a high rate of structural integrity that the effects of hormonal deficiency take much longer to produce symptoms; but, at the same time, the results of the deficiency are just as, if not more, dangerous to the long term health of the male and female body.

High-Turnover Osteoporosis

Primary Type One Osteoporosis is often referred to as high-turnover osteoporosis because trabecular bone tissue degrades at a rapid pace as the disease approaches a symptomatic point. Trabecular bone tissue is also referred to as Spongy Bone or Cancellous Bone. This type of bone tissue has a large amount of surface area because of its naturally porous structure. Cancellous bone degrades quickly as a result of osteoporosis because the already porous bone becomes so structurally degraded that it becomes highly prone to fractures and breakage.

This type of bone tissue is mostly located near the edges of bones, near the cartilage in the areas which the bones make contact with one another. Trabecular bone tissue is especially densely allocated in the areas of the wrist and the spine, and for this reason, patients who suffer from this form of osteoporosis are much more at risk for carpal tunnel syndrome and spinal fractures.

Primary Type 2 Osteoporosis

Primary Type Two Osteoporosis is the form of the disease that most men and women associate with Osteoporosis because of its relationship with hip fractures. Type Two also affects women at a higher rate than men. This form is only twice as common in females as males, so it is more of a risk for men than Primary Type One Osteoporosis. This manifestation of the disorder usually begins to appear when adults enter their seventies and eighties.

Primary Type 2 Osteoporosis is often, but not necessarily, related to Estrogen and Testosterone Production, but rather Calcium Deficiency and Vitamin-D deficiency, which are the two vitamins most highly associated with bone health and structural integrity. There is also a significant amount of evidence that this disorder is linked to higher activity in the Parathyroid gland associated with the aging process.

What is Primary Type Two Osteoporosis?

This type of Osteoporosis occurs when the bones have degraded to a point at which even the cortical bones begin to break down. Cortical bones are the strong hard casings of the bone which protect the functional interior bone and support the weight of the body throughout day-to-day function. Primary Type Two Osteoporosis is associated with a much higher likelihood for breaks of the long arm and leg bones as well as the hips.

The Hips are Particularly Vulnerable to Breakage

Hips are highly susceptible to this form of osteoporosis because, although these bones are quite thick and structurally strong, they are still thinner than many of the other bones of the body. In addition to this, the hip bones take on an extraordinary amount of stress because of their central, pivotal location in the body. Another reason that the hip bones are highly at risk for fracture and breakage is that seemingly innocuous falls become incredibly hazardous as Osteoporosis worsens, and the hip bone is most likely to take the majority of damage in this type of fall. One slip and the hip bone could fracture or even shatter as a result, depending on the force of the fall and the progression of the disease.

Type One and Type Two Osteoporosis Are Unique Disorders

Although Primary Type One and Primary Type Two Osteoporosis are considered separate disorders, and Type Two can sometimes occur even in the absence of Type One Osteoporosis, Type Two Osteoporosis can also be the result of a progression of Type One. Over time, the structure of the hips and spinal column degrades to a point that these thicker bones begin to show symptoms as well.

It takes much longer for these bones to show signs of wear because the cortical bones are much more compact. Dangerously low levels of Bone Mineral Density take longer to result in fractures and breaks. This is one reason why Type One Primary Osteoporosis is most common between the ages of 55 and 70 and Type Two is more common among patients 70 and olderType Two effects bones which are more structurally sound.

Secondary Osteoporosis

Secondary Osteoporosis is the result of factors outside of general nutrition, parathyroid activity, and sex-hormone activity. In men and women who are healthy, the bone tissue is constantly restructuring itself, replacing aging cells in order to maintain optimal bone strength. To provide an example, this is why after you break a bone when you are young, the bone is able to rebuild and even become stronger than it was before. Have you ever broken a bone? Run your hand along the area of bone that was broken and you will likely feel that this area of bone is slightly thicker than the bone tissue surrounding it. This is because the body reacted to the damage by making the bone even stronger than it was before.

Bone Remodelling and Osteoporosis

The process of natural bone restructuring is known as remodelling. The skeletal system is just like a road or a building. Stress wears on the bones in the same way that it wears on the tresses of a house or the concrete foundation of a street. Eventually, the street needs to be repaved, and the support structure of a building has to be inspected and maintained. In the body, the bones go through the process of remodelling in order to keep the bones constantly in a state of optimal strength.

Bone Formation and Bone Resorption

This natural process of remodelling is the result of a delicate balance of two internal processes. The first process is known as Bone Formation. In the process of Bone Formation, the bone tissue pulls calcium from the blood stream in order to use it to build and strengthen the bones. The cells which perform the task of rebuilding the bones are known as osteoblasts. These cells use enzymes and chemical reactions to pull the calcium from the blood, mineralizing it and affixing it to the bones in order to strengthen them.

The second process is known as Bone Resorption. Bone Resorption is the process by which older bone cells are broken down and turned back into parts which the osteoblasts can then use in order to create healthy new bone cells. Osteoblasts and osteoclasts function through the influence of hormones known as Paracrine Signallers. Over the course of a year, ten percent of bone tissue goes through the process of remodelling. When balanced, it is a slow yet effective process for maintaining bone health.

Bone Turnover Rate and Osteoporosis Diagnosis

The mathematical formula regarding the maintenance of Bone Remodelling is known as the Bone Turnover Rate. A healthy Bone Turnover Rate would be a point at which bone tissue is replaced efficiently, discarding or recycling old tissues and maintaining a constant level of bone strength. Osteoporosis occurs when the Bone Turnover Rate gets out of balance and the bone tissue is not recycled and remodelled at the rate that the bone is either degraded by osteoclasts or naturally breaks down as a result of the aging process of the bone cell. Secondary Osteoporosis is the result of osteoclasts that break down bone faster than osteoblasts can rebuild them, causing the bones to break down and become porous as a result.

Causes of Secondary Osteoporosis

Secondary Osteoporosis can be the result of a number of issues related to hormone imbalance, including:

Hyperparathyroidism The parathyroid glands have a single purpose. They are responsible for regulating calcium balance throughout the human body. Hyperparathyroidism is a common cause of Secondary Osteoporosis. The Parathyroid Glands release a hormone known as Parathyroid Hormone, abbreviated PTH, into the blood stream. Hyperparathyroidism causes the body to constantly send messages to the bones demanding that they release calcium into the blood stream. This prevents the Osteoblasts from being able to produce new bone at the rate that bone is being degraded, leading to osteoporosis over time.

Hyperparathyroidism leads to a constant elevation of calcium in the blood stream as well, because the body cannot excrete the calcium released by the bones quickly enough. The kidneys are also overworked, often leading to kidney stones. Kidney stones are simply calcium deposits that form in the kidneys. If they grow large enough they can block the path of excretion, causing great pain. Hyperparathyroidism is usually the result of a parathyroid tumor which causes the organ to release PTH in overdrive. This form of Osteoporosis can strike men, women, and children of all ages, and will not be cured until the tumor is removed or the disorder is otherwise corrected.

Hyperthyroidism Overactive Thyroid Glands prevent the body from storing phosphorus and calcium properly. Hyperthyroidism causes bone turnover to occur at an escalated pace, and the osteoblasts are no longer able to work fast enough to rebuild bone. Hyperthyroidism also causes the body to pull calcium and phosphorus out of the bones and diet where they are excreted through the stool or through urination. The osteoclasts break down old bone, and the excess materials are pulled into the blood stream.

This disorder becomes even more problematic when combined with Estrogen Deficiency, Testosterone Deficiency, or Human Growth Hormone Deficiency, because the two primary keys to bone health are proper nutrition and proper hormone balance. Hyperthyroidism often causes an issue known as hypercalcemia, where the blood stream is flooded with excess calcium. Calcium levels in these patients can be as much as 25% above normal.

Diabetes Insulin desensitization which results in dangerous levels of blood sugar. Diabetes has been proven to be correlated with reduced bone density, resulting in an increased incidence of osteoporosis. Patients who suffer from Diabetes have reported a history of bone fractures at a rate which is over 12 times higher than their counterparts without diabetes. One reason that Diabetes may affect osteoporosis is that high levels of blood sugar in the body reduce the production of Human Growth Hormone by the pituitary gland.

This reduction of HGH production leads to a cascade of issues associated with HGH Deficiency, and Osteoporosis is one of the most dangerous symptoms of Hypopituitarism. Human Growth Hormone directly contributes to bone health, because Endogenous Growth Hormone is converted into one of the primary Paracrine Signallers known as Insulin-like Growth Factor One. IGF-1 plays a direct role in the proper function of Osteoblasts, and when those cells do not function optimally, the bone begins to degrade as a result.

Cushings Syndrome Cushings Syndrome is defined as symptoms which occur as a result of long-term excess levels of cortisol in the body. Cushings Syndrome is a symptomatic form of hypercortisolism. Hypercortisolism is simply defined as excess levels of cortisol. Cushings Syndrome leads to bone issues in a manner which is similar to Diabetes, although other symptoms of the two diseases are incredibly different.

Long term hypercortisolism leads to a significant decrease in the functional capacity of the osteoblasts. Cushings Syndrome is common among football players and other professional athletes because of the use of Cortisol as an anti-inflammatory and pain relieving agent. Although Cortisol is the bodys natural response to pain and inflammation, it also hinders the bodys ability to produce Testosterone, Estrogen, and other hormones which are related with long term health. Hypercortisolism also leads to symptoms of Testosterone Deficiency such as mood disorders, hypertension, diabetes, and muscle atrophy in addition to osteoporosis.

Non-hormone Related causes of Secondary Osteoporosis include:

Metastic Bone Disease - This is the stage of cancer in which cancer cells spread throughout the body after being released into the bloodstream. There are multiple reasons why this causes osteoporosis dependent upon the regions of the body affected.

Leukemia This causes White Blood Cells to be generated at a highly escalated rate. This incredible increase in white blood cell production interferes with the proper function of osteoblasts, preventing them from restoring calcium and phosphorus levels in the bones. White blood cells are produced by the bone marrow in the same region in which osteoblasts primarily operate, and the proliferation crowds out the osteoblasts.

Multiple Myeloma This is a stage of bone cancers where multiple tumors grow throughout bone and bone marrow tissue. Multiple Myeloma causes the bone marrow to produce plasma at an uncontrollable rate which prevents the bones from producing other important cellular organs which regulate Bone Remodelling.

Thalassemia This is a hereditary form of anemia in which the body does not produce enough red blood cells for the body to function optimally. This causes symptoms of osteoporosis and osteopenia to occur early in the life span, because the Osteoblasts are not able to build bone as fast as it is broken down. Thalassemia is also associated with Human Growth Hormone and IGF-1 Deficiency.

Case Study: Osteoporosis and HGH Deficiency

A study by Dr. Christian Wuster is related to the effects of paracrine signals on the maintenance of the cycle of bone remodelling.

Dr. Christian Wuster is a member of the Department of Internal Medicine, Internal Endocrinology, and Metabolism at the Heidelberg University Medical Clinic in Germany. In a recent study released by he and his associates at the university, they provided evidence that HGH Deficiency is associated with a reduction in bone mass that causes an increased rate of osteoporosis, as well as vertebral fracture.

Children who suffer from juvenile Growth Hormone Deficiency struggle with inferior bone mineralization as a result of their deficiency. Untreated, this prevents these juvenile patients from experience the growth associated with puberty. Osteoporosis can also occur as a result.

Bone Turnover Rates Briefly Decline Because of HGH Treatments

When utilizing Human Growth Hormone Replacement Therapy for patients with Growth Hormone Deficiency, the initial rate at which bone turnover occurs is elevated for around the first six months to year of treatment. This is because the system of bone remodelling is in the process of returning to optimal function. Before osteoblasts can do their jobs to full capacity, the osteoclasts must play a role in feeding recyclable materials for the process to occur at an optimal rate. After this point, the rate of bone turnover reaches a balanced point, and the bones begin to strengthen as a result.

From research involving individuals who have acromegaly, there is evidence that dense bone mass increases as a result of Human Growth Hormone Injections. The therapy has no effect on the spongy bones in patients who do not suffer from Hypopituitarism. In patients who suffer from hypopituitarism, trabecular spongy bone mass decreases in area. Although there is a decrease, the trabecular bones do have an increased mineral content and their surface area increases.

In Cancellous Tissue, Greater Density Does Not Always Mean Greater Strength

This means that although total bone mass decreases slightly, the structural integrity of the bones actually increases because the bone is healthier because the bone is more optimally composed. One issue with osteoporosis in the trabecular bones is that they are not remodelled efficiently. This means that bone tissue begins to break down and weaken and lose its mineral content even though overall mass remains stable or even increases slightly.

This data regarding trabecular mineral content was previously shown to be true in laboratory animal studies involving rats. In patients who suffered from Juvenile-Onset Growth Hormone Disorder, HGH Replacement Therapy can be used in order to maintain bone health, maturation, and Mineralization. Until a juvenile patient achieves their final adult height they are injected with high doses of Human Growth Hormone in order to simulate the natural process of puberty which is caused by the endogenous production of high levels of Human Growth Hormone by the pituitary gland.

Adult HGH Hormone Replacement Should Emulate Normal Adult HGH Secretion

After the patient reaches Final Adult Height, smaller doses of Human Growth Hormone should be used in order to emulate HGH levels in the body during adulthood. Although Human Growth Hormone is known primarily for its function in the growth spurt of puberty, it is also vitally important to overall health throughout the lifespan.

HGH Balance is Vitally Important to a Healthy Life

Although Dr. Wusters study shows the importance of Human Growth Hormone in order to prevent Osteoporosis, Human Growth Hormone is also important in maintaining a number of other vital functions as well. HGH encourages a healthy Body Mass Index by facilitating the breakdown of adipose fat tissue. Human Growth Hormone increases muscle mass by increasing the amount of energy and nutrients available to the muscles during exercise. These are just the three most obvious changes associated with Human Growth Hormone Replacement Therapy.

Female Osteoporosis often Caused By Pituitary Imbalance

In female patients who suffer from Osteoporosis, Wuster finds that the Growth Hormone/Insulin-like Growth Factor 1 Axis is disturbed and incorrectly regulated, which results in a reduction of bone strength. Post-Menopausal osteoporosis patients have been shown to have low levels of IGF-1 and IGFBP-3 levels which lead researchers to conclude that the osteoporosis is caused at least in part because of a reduction in Growth Hormone Secretion or some other issue involving the Hypothalamic-Pituitary Axis which prevents IGF-1 and IGFBP-3 from being produced properly. IGFBP-3 is Insulin-like Growth Factor-Binding Protein Three. The issues caused by this exceed those caused by general hormone decline known as Somatopause. Early-onset Somatopause could present issues in some patients who suffer from arthritis, 24 hour Growth Hormone Profiles do not change among patients who suffer from osteoarthritis and osteoporosis.

What Weve Learned: Wuster, Osteoporosis, and HGH

Wusters study provides evidence that there are benefits to utilizing Human Growth Hormone shots as a treatment for Osteoporosis. This is because Human Growth Hormone improves bone mineral density and helps sustain a healthy balance of osteoblast-osteoclast function leading to more efficient Bone Remodelling. These benefits will produce their largest impact in patients who are late post-menopause and suffering from Primary Type-Two Osteoporosis, because the dangers of cortical bone and spinal column fractures become very high during this period. Human Growth Hormone Replacement Therapy may also be able to prevent Osteoporosis and can greatly alleviate the symptoms of Primary Type-One Osteoporosis.

Information regarding Dr. Wusters study was acquired from the National Library of Medicine

Osteoporosis and Hypogonadism

Bone health is largely regulated by sex hormones in both males and females. These Hormones play a role alongside Human Growth Hormone in producing Final Adult Height in pediatric patients. In adults, androgens play an important role in the maintenance of the skeletal system as well. There is significant research that correlates deficiencies in Estrogen, Testosterone, and other Sex Hormones with Osteoporosis and other bone disorders.

Estrogen hormones play a vital role in bone health. The male body has the ability to convert Testosterone into Estrogen in order to maintain bone health, although excess estrogen production is very unhealthy in men. In men, the two organs responsible for Testosterone and Estrogen production are the adrenal glands and the testes. In females, the adrenal glands as well as the ovaries create Estrogen and Testosterone. In males, Testosterone is produced primarily, and Estrogen is produced more as a byproduct. In females, Estrogen is the primary hormone produced.

The Roles of Estrogen and Testosterone in Remodeling

The sex hormones of both sexes have been linked to the production of osteoblastic cells which work to maintain healthy bone structure. The male and female sex hormones both play their own roles in maintaining homeostasis. Progesterone and Estrogen slow down osteoclast cells, reducing the rate at which bone turnover occurs. Testosterone directly leads to the reproduction of Osteoblasts, increasing the rate at which Bone Remodeling occurs. Estrogen Deficiency causes Osteoporosis because it encourages the heightened activity of osteoclasts.

Testosterone Deficiency causes osteoporosis because it inhibits the function and production of Osteoblasts. For this reason, Testosterone and Estrogen Deficiency lead to Osteoporosis and Osteopenia. Estrogen Deficiency is uncommon in males because the body converts Testosterone into Estrogen. The primary problem which occurs in males is that high levels of adipose fat or cortisol can upset the Sex Hormone Balance, leading to Testosterone Deficiency at the expense of Estrogen and Cortisol conversion.

Female Obesity and Osteoporosis

In females, obesity is not linked to Osteoporosis and higher body fat levels are associated with stronger bones. Being underweight is correlated with higher rates of Osteoporosis. A healthy weight for women is keyenough body fat to reduce the risk of Osteoporosis, but not so much that it inhibits longevity in other ways. In males, on the other hand, obesity has been causally linked to Osteoporosis.

Healthy Testosterone Levels Encourage Male Osteoblast Production

Male muscle mass has also been shown to be linked to bone health as well. Healthy Male Testosterone Levels are vital for bone health because they encourage the activity of the osteoblasts. Although obesity leads to greater Estrogen production which slows down osteoclast metabolism, lower Testosterone levels greatly slow down the reproduction and development of osteoblasts which still place Bone Turnover Rates out of balance.

Human Growth Hormone and Bone Mineral Density

Human Growth Hormone is an essential ingredient to bone health in addition to Testosterone, Estrogen, and Progesterone. Our knowledge of how the sex hormones relate to Bone Mineral Density are much more evolved than our knowledge of how Human Growth Hormone contributes to bone health, but there is obviously a direct correlation.

Effects of HGH Deficiency

Wusters study is one of many which attempt to answer the question regarding the mechanism by which Human Growth Hormone induces bone health. It is clear that the anabolic processes of Human Growth Hormone and IGF-1 cause the increase in height and bone mass during puberty. Its also been shown that Healthy Human Growth Hormone levels maintain the skeletal foundation during adulthood as well. Adult-Onset Human Growth Hormone and IGF-1 Deficiency have also been clearly linked to a number of negative health outcomes regarding the aging process as well, including:

Reduced Muscle Strength and Mass IGF-1 creates an energy pipeline from Adipose Fat tissue to the muscles, providing them with the energy that they need to function optimally. Without proper sustenance, the muscles do not have the nutrients they need to become larger and stronger and can atrophy as a result.

Lower Thresholds for Endurance Lower levels of energy as a result of HGH Deficiency reduce the amount of physical and mental energy at the disposal of an individual, leading to problems with cognition, focus, and physical endurance for exercise

Increase in Adipose Fat As a result of Human Growth Hormone Deficiency, fat around the midsection begins to pool at an increased rate, because IGF-1 is one of the primary metabolites which prevent fat accumulation.

Lower Bone Mineral Density IGF-1 and Human Growth Hormone encourage the production and efficiency of osteoblasts, which increase the rate at which new bone is generated and old bone tissue is replaced.

HGH, IGF-1, and Bone Health

Human Growth Hormone and its derivative IGF-1 both play a direct role in overall bone health. HGH directly causes osteoblastic cells to be formed in addition to Testosterone. Although HGH is required in order to influence osteoblast creation, IGF-1 is necessary to encourage many of the internal processes of the osteoblast cell. Rapid height increases during the period of puberty are largely the result of Human Growth Hormone, because excess HGH levels in the bones encourage them to grow in length.

After the epiphyseal plates harden in late adolescence, growth no longer occurs and HGH production decreases to normal adult levels which stimulate the production of IGF-1 while not inundating the bones with excess HGH. Excess levels of HGH are associated with a number of negative bone issues such as arthritis, carpal tunnel syndrome, and acromegaly. Acromegaly is a bone disorder in which the bones of the face, hands, and feet continue to grow past puberty as a result of HGH stimulation, leading to physical contortions in bone structure.

IGF-1 also effects the production of osteoblasts, but at a much more modest rate that is beneficial to those in adulthood. In addition to this, the hormone increases the functional ability of osteoblasts after creation. IGF-1 plays an integral part of normal bone density and bone mineralization because IGF- increases the creation of collagen while inhibiting its breakdown. IGF-1 affects the function of osteoclasts, but so far, research has been unable to precisely figure out how IGF-1 receptors on osteoclasts affect the function of those cells.

Risk Factors for Osteoporosis: Could I get Osteoporosis?

Although Osteoporosis is a fairly common disorder, it certainly does not affect all people and one can greatly reduce the risk of the disorder through healthy living and being proactive. There are a number of factors which can increase your chances of coming down with the disease. Some of the factors which can lead to Osteoporosis are hereditary, which means that they are a result of your personal and individual genetic history. Other factors are the result of particular lifestyle and nutrition choices or the result of particular medicines.

Medical and Biological Risk Factors for Osteoporosis

Sex Females have much greater odds of being diagnosed with Osteoporosis than males. Females are 6 times more likely to be diagnosed with Primary Type One Osteoporosis and twice as likely to come down with Type Two Osteoporosis. With Secondary Osteoporosis, the odds fluctuate dependent upon the root cause of Osteoporosis. There are four main reasons why women suffer from Osteoporosis more than men. Women are on average thinner than males. Women have naturally lighter bones than males. Menopause is correlated with a much sharper reduction in Hormone levels than male Andropause, which is a slow and steady decline that takes decades. The forth reason is that women tend to live longer than males, and Osteoporosis is correlated tightly with age.

Race  Asians and Caucasians are more likely to suffer from Osteoporosis than other races. African American women have stronger bones on average than their Caucasian counterparts. African American women experience hip breaks and fractures at a rate of around half as often as their Caucasian counterparts.

Age  Age is one of the most significant factors correlated with osteoporosis. Bones begin to weaken slowly starting around the age of thirty. It takes decades for the effects of Osteoporosis to begin to show. In females, Primary Type One Osteoporosis tends to become symptomatic when women are in the fifties and sixties. Primary Type Two Osteoporosis usually occurs in the seventies or eighties. The age at which Secondary Osteoporosis occurs can vary greatly dependent upon the source of bone deficiency.

Heredity Osteoporosis is highly correlated with genetic history. If older men or women in your family suffered from spinal column or hip fractures, then you may be at a greatly enhanced risk of the disorder. If you have many relatives who suffer from back issues which result in curvature of the spine and an inability to straighten the back, you are also possibly at risk as well.

Body Frame  Women who are thin or petite are at a greater risk of Osteoporosis. Healthy body fat levels are related to elevated female Estrogen levels which encourage the proper maintenance of bone mineral density. Women who struggle with anorexia are highly at risk for Osteoporosis, and long term anorexia can lead to Early-Onset Osteoporosis.

Post-Menopausal Women  Women who have already experienced menopause are at the highest risk of Osteoporosis because of the sharp decrease in Estrogen and other sex hormones. It takes ten to fifteen years for the symptoms to start to appear, and many women choose to undergo Estrogen Replacement Therapy in order to maintain the health of the bones. The bones are incredibly resilient, so it takes years of hormone deficiency for the bones to deteriorate as a result, but the deterioration is linked with high rates of mortality.

Estrogen Deficiency Females who have suffered from Estrogen Deficiency their entire lives are at a very high risk of Osteoporosis if they have not been properly treated with Estrogen Hormone Replacement Therapy. Estrogen Deficiency can be the result of early menopause, late puberty, anorexia, or any method of suppressing the feminine cycle, as well as the total absence of sexual development.

Medicine Use  A number of medicines raise the incidence of Osteoporosis because they have a negative effect on bone mineralization and mass over long term usage. Anticoagulants, Immunosuppressants, anti-epileptic drugs, and steroids have been shown to raise the risk of osteoporosis, as well as thyroid suppression. Thyroid and Parathyroid Hormone are the most direct contributors to bone health, and calcium cannot be effectively used and recycled for Bone Remodeling if these hormones are imbalanced.

Diet and Nutrition Problems  Malnutrition, anorexia, chronic liver disease, and syndromes which affect the absorption of Calcium and Phosphorus can greatly increase the chances of osteoporosis.

Metabolic and Endocrine Causes Hemochromatosis, diabetes, and thalassemia all lead to increased risk for osteoporosis. Thalassemia is a genetic disorder which leads to anemia and hinders bone health greatly. Diabetes leads to erratic and abnormally high levels of blood sugar which decrease the effect and secretion of HGH and IGF-1. IGF-1 and Human Growth Hormone are incredibly important in the maintenance of healthy bones and Osteoporosis commonly results from diabetes. Hemochromatosis is a disease which causes the body to absorb an abnormally high level of iron. Although the effects of this disorder do not cause problems immediately, after thirty to forty years, the symptoms appear and the effects can be dramatic. Excess blood-iron levels are believed to suppress osteoblast activity, leading to bone mineral breakdown and Osteoporosis over time.

Other Disorders Rheumatologic disorders, renal tubular acidosis, certain cancers including myeloma, mastocytosis, and Downs syndrome also increase the incidence of Osteoporosis.

Lifestyle Choices Increase Risk for Osteoporosis

Calcium Deficiency Women under the age of fifty should consume 1000 milligrams of calcium daily. Women over seventy should have 1200 milligrams of calcium. Calcium becomes a greater concern for males at the age of seventy and older. Men under seventy should include 1000 milligrams of calcium in their diet daily. Men over that age should take or consume 1200 milligrams each day. Calcium Deficiency is defined as daily intake of 300 mg, but recommended calcium intake is much higher.

Vitamin D Deficiency Both sexes should consume 400-800 IU of Vitamin D each day if they are less than fifty years of age. Men and women over 50 should consume 800-1000 IU. This number can vary quite a bit, and some people need more than others. It is recommended that the upper safe limit for Vitamin D consumption is 4,000 daily IU. Caucasians and those with lighter skin are more at risk for Vitamin D deficiency and need more Vitamin D each day. Melatonin naturally converts sunlight into Vitamin D, so African Americans and other dark skinned people need less supplemental Vitamin D. Vitamin D is a key component of Calcium intake which helps absorb calcium from its dietary form to a usable form. Vitamin D can be found in a number of foods, including certain fish, fortified cereals and milks, and egg yolks.

Excess Caffeine Ingestion Although it does not appear that drinking caffeine has a negative effect on calcium levels in healthy patients, those who do not consume enough calcium in their diet will find that their Calcium Deficiency is made worse by having too much caffeine.

Sedentary Lifestyle Healthy levels of Human Growth Hormone and IGF-1 are important for maintaining healthy bones. A sedentary lifestyle is one of the worst culprits in inducing or exacerbating Human Growth Hormone Deficiency. HGH is released at its highest rates during two periodsduring deep sleep and during exercise. Living a life without exercise and physical exertion can lead to Hypopituitarism which inhibits the development and propagation of healthy and optimally functioning osteoblasts. In addition to this, the bones need exercise as much as any other organ, and physical exercise also creates pressure on the bones which encourage the body to maintain their structural integrity.

Use of Nicotine and Tobacco Smokers lose bone density at a rate higher than nonsmokers. An analysis of twenty nine studies shows that the risk of hip fracture increases by 17% at age sixty, 71% at age eighty, and a whopping 108% at age ninety. Although these effects are cumulative over time, making the decision to quit smoking at any age will reduce future risk of fractures associated with Osteoporosis and tobacco use.

Alcohol Heavy use of alcohol can have a negative effect on calcium absorption. Alcohol when used in excess can cause the pancreas to take in nutritional Vitamin D and calcium at a reduced rate. It also overloads the liver, which can reduce the efficiency of Vitamin D activation. Heavy alcohol use has been shown to destroy osteoblasts as well. Excess alcohol can also disturb Estrogen secretion in females. Chronic alcoholism causes an increase in parathyroid hormone production as well as cortisol production. Both of these hormones have a negative effect on the Bone Remodeling cycle, leaching Calcium from the bones and out through bodily excretions.

How Can I Stop Osteoporosis?

Even if you are not at a genetically high risk of Osteoporosis, there are a number of ways that you can strengthen your bones and reduce the threat of Osteoporosis.

Increase Calcium Consumption

The simplest way to reduce the risk of Osteoporosis is to take in a healthy amount of calcium each day. Choose foods which are ripe with calcium or take a daily calcium supplement in addition to the calcium that you naturally take in through diet. It is important to maintain healthy calcium consumption throughout your life because of the long term consequences of calcium deficiency. Poor nutrition habits you have now may come back to bite you decades later if you do not keep a preventative mindset. The bones begin to lose mass after the age of thirty, so it is important to maintain adequate calcium levels throughout childhood and early adulthood so that your bones can be as strong as possible when decline inevitably begins. After the age of thirty, calcium intake will help minimize bone loss while strengthening bones through proper mineralization, reducing the risk of fractures later in adulthood.

If you are utilizing calcium pills, make sure that they also have Vitamin D, because of the positive effect that Vitamin D has on calcium absorption. Also pay attention to the type of calcium supplement that you buy. Calcium carbonate is inferior to calcium citrate because it is not absorbed by the body as easily. One other advantage to calcium citrate is that it does not have to be taken with food. If you use calcium carbonate, make sure you take the supplement with food in order to ensure sufficient absorption.

Vitamin D

Maximize Vitamin D consumption either through Supplementation or changes in diet. Although less may provide you the benefits that you need, consuming 1200-2000 IU daily will ensure that you are getting the level of Vitamin D you need at any age without putting you at any risk for taking too much. Again, good foods to eat for Vitamin D are Fortified foods, egg yolks, shrimp and many fish including pink salmon, sardines, mackerel, and halibut. Cod liver oil makes a great supplemental form of Vitamin D as well.


There are three important forms of exercise when it comes to preventing or slowing down Osteoporosis. The first form of exercise is weight-bearing exercise. This form of exercise is simply staying on your feet and getting out and about. You can go hiking. You can dance. Literally anything that keeps you moving and on your feet for an extended period of time qualifies. One important note biking and swimming are not effective forms of weight-bearing exercise. Although they tax the cardiovascular system, they do not put the form of load-bearing stress on the body which maximally benefits those at risk of Osteoporosis. Thirty minutes to an hour of physical exertion weekly is optimal to provide the best health benefits.

Resistance training is also very important when preventing or slowing Osteoporosis as well. Resistance training is simply described as weight lifting. This form of exercise makes the muscles larger and stronger, and helps the bones become more structurally sound. You can lift weights or utilize spring or tube systems to provide resistance without lifting weights. Exercising in water is also a very effective means of resistance training, especially for older men and women who are at high risk of osteoporosis and bone fractures. For optimal results, one should work out in this manner at least three times each week. It is also incredibly important to alternate muscles, both to reduce wear and tear, and because the muscles repair and rebuild themselves primarily during rest periods.

Resistance training is effective largely because it encourages your body to secrete more Human Growth Hormone. HGH helps make your bones more resilient and strengthens the muscles as well. For patients who are taking Human Growth Hormone Replacement Therapy or IGF-1 Injections, Weight training increases the effectiveness of these hormone shots.


Stretching and flexibility exercises are incredibly beneficial for those that are at risk for Osteoporosis. Flex exercises increase the ability of the joints to withstand stress which can greatly reduce the threat of falls or other types of injuries. Limber joints allow you to avoid bad falls and prevent minor and major bone fractures. If you are looking for a simple way to increase flexibility, going through routine stretches every day is a simple and incredibly safe way to get limber.

If you really enjoy flexibility exercises and would like to combine stretching with cardiovascular exercise, yoga is a fantastic way to keep in shape. If you have already had issues with Osteoporosis in the past, make sure that you engage in stretching exercises or other forms of exercise which do not overtask the hips and spinal column to reduce the risk of further issues.

The important thing is to make sure whatever you do is safe for your body. Talk to your doctor before you alter your routine of physical activity, especially if you are older and at high risk for complications resulting from Osteoporosis. Its vitally important that you engage in a form of exercise that your body can handle while also ensuring that you are putting stress on your muscle, bones, and joints.

What Medicines Treat Osteoporosis?

As of today, there are a handful of medicines which have been shown to be very effective in preventing or treating Osteoporosis

Estrogen Hormone Replacement Therapy (HRT)

Estrogen HRT has been proven to be highly effective in both staving off and alleviating the effects of Osteoporosis in women. Estrogen Treatments have been shown to greatly decrease bone loss while also boosting bone density in the hips and spine, the two areas most susceptible to Osteoporosis. The spinal column and hips are also the two areas in which Osteoporosis creates the most devastating injuries. For female patients, the risk of bone fracture in these two vital areas is reduced significantly through the usage of Estrogen Replacement Therapy.

Estrogen Patches, Pills, and Injections

Generally, Estrogen HRT is provided via patch and pill, although Estrogen injections are often used as well. Estrogen Injections are primarily used to alleviate the effects of menopause, and Estrogen Patches and pills are more often used in order to treat symptoms of low Estrogen levels such as Osteopenia, Osteoporosis, and low libido. Estrogen Hormone Treatments are effective when began at any age, but they are most effective when used as a preventative measure in order to attempt to bypass Osteoporosis altogether.

Estrogen Replacement Therapy is Paired with the Hormone Progestin

One of the main risks associated with taking Estrogen Replacement Therapy alone is that can raise the risk of experiencing endometrial cancer, which is a cancer of the uterine lining. In the menstrual process, spikes in estrogen levels cause the line of the uterus to thicken in a monthly cycle. Excess use of Estrogen can lead to undesired growth of endometrial tissue which can in some cases develop into cancer. New therapies have been created which greatly reduce the risk of endometrial cancer when utilizing Estrogen Hormone Replacement Therapy. Today in most cases where Estrogen HRT is utilized, a hormone known as progestin is provided alongside estrogen in patients who still have a uterus. Progestin prevents endometrial hyperplasia, which is the rapid build-up of endometrial cells which develop as a result of unopposed Estrogen Replacement Therapy.

Why are Estrogen and Progestin used together?

Normally in a hormonally stable woman, Estrogen and Progestin work as counterbalances to one another in order to maintain the normal cycle of endometrial development. After menopause, the release of both of these hormones drops precipitously. Because introducing exogenous Estrogen does not cause an increase in progestin, progestin must be supplementally supplied as well.

Side Effects of Estrogen HRT

Side effects of Estrogen Hormone Replacement Therapy include hypertension, breast sensitivity, bloating, and nausea. Evidence suggests that while high blood pressure can be an issue in female patients utilizing birth control products which include Estrogen. Estrogen Replacement Therapy provides a much lower level of Estrogen which is not believed to lead to hypertension. Water Retention is a direct result of estrogen use and in most patients will not be an issue, or will not be severe enough to suspend or alter therapy. If you experience bloating as a result of Estrogen Replacement Therapy, you can talk to your doctor about dietary changes to resolve bloating issues, and there are also medications you can take which will help to resolve the issue as well. Some patients respond to oral estrogen negatively and experience nausea as a result. For these patients, switching to a patch should resolve the issue entirely. Breast tenderness can be resolved either by changing to a patch or by adjusting the dosage.

Estrogen and Breast Cancer Risk

The current body of scientific evidence does show that long term Estrogen Replacement Therapy is correlated with an increased risk of breast cancer, so if you are at an increased risk of breast cancer or currently have breast cancer, you should avoid Estrogen HRT unless you have been given the okay by your physician. Although Estrogen Replacement Treatments are effective at alleviating Osteoporosis, it is not commonly prescribed for periods longer than a few years, because of the increased risk of breast cancer that occurs with prolonged usage.

Testosterone Hormone Replacement Therapy

Testosterone HRT is often effective in male patients who suffer from Osteoporosis. Male Osteoporosis often goes unidentified and misdiagnosed because of its relative rarity, but male hypogonadism can lead to a hormone imbalance which can negatively impact the bone mineral density of the skeletal system.

Male Osteoporosis Less Common

Although Male Osteoporosis is much less common, it is still a major issue that occurs with enough frequency that male bone health should be cautiously monitored with age. Testosterone plays a vital role in the maintenance and proliferation of the osteoblasts, and in patients who suffer from Low Testosterone and especially those who have total hypogonadism need Testosterone Treatments in order to strengthen the bones as well as maintain physical strength, cognitive ability, and sexual libido.

Increase in Male Osteoporosis in Recent Years

There has been an uptick in diagnoses of Male Osteoporosis in the last generation, and there are a number of factors which may contribute to this. Men are living longer than they once were, and they are more prone to experiencing Primary Type Two Osteoporosis, which tends to effect males in their seventies and eighties rather than earlier in life like Primary Type One Osteoporosis, which affects females significantly more than males.

Osteoporosis and the Sedentary Workplace

Also, because males are more often working in sedentary environments, Testosterone Deficiency is more of an issue than it has ever been before. In Great Britain, for example, it is believed that Osteoporosis affects one in every twelve men and one in every six males over the age of eighty will experience a fractured hip at some point in the rest of their life. Men who suffer from hypogonadism have been shown in scientific research to experience rates of bone turnover that are far higher than healthy men.

Male patients who have experienced minor hip or spinal fractures are encouraged to seek Testosterone Replacement Therapy. In addition to this, Hypogonadal patients who have been proven to have reduced Bone Mineral Density will also likely benefit greatly from Testosterone injections.

Testosterone Replacement is a Natural Therapy

Many physicians are now recommending Bio-Identical Testosterone HRT as an alternative to Bisphosphonates because Testosterone HRT is a much more natural form of therapy which mimics and enhances the bodys natural processes. With all of the other positive benefits provided by Testosterone Replacement Therapy for Osteoporosis, it seems to be a clear choice for male patients as Osteoporosis and Low-T begin to manifest themselves with age.

Testosterone Replacement Therapy for Low-T and Osteoporosis produces minor or no side effects in the great majority of patients. The most reported side-effects of BioIdentical Testosterone Hormone Replacement are skin abrasion and rashes at the administration site, slightly increased hemoglobin count, decreased HDL (Healthy Cholesterol), and acne.

Testosterone Replacement Therapy Produces Few Significant Side-Effects

A cross-section of ten studies showed no major adverse reaction to therapy in any of the trials. Testosterone should not be used by patients who are suffering from prostate cancer, because Testosterone Hormone Replacement Injections can exacerbate existing prostate tumors. Also, patients who utilize anti-coagulants should be especially cautious with Testosterone Replacement because of the effect that Testosterone Replacement sometimes has on hemoglobin counts.

Human Growth Hormone Replacement Therapy

Growth Hormone Injections are a new method for Osteoporosis treatment in comparison to the others listed, but it still shows promising results. The Wuster Study cited earlier in this article is evidence in favor of Human Growth Hormone HRT, and there are many other studies which present similar evidence. HGH Hormone Replacement Therapy works by encouraging the proper function of Osteoblasts through the intervention of exogenous IGF-1.

HGH Makes Osteoporosis Prevention Easier

In addition to this, HGH Hormone Treatments also encourage physiological changes which lead to enhanced outcomes. Human Growth Hormone alleviates adipose fat accumulation, which discourages excess estrogen production in males and also increases the effectiveness of endogenous HGH secretions.

HGH Injections also have a tendency to reduce fatigue and bolster muscle mass and strength, which helps patients maintain an exercise program which can help them strengthen their bones and muscles in a way that enhances outcomes and reduces the risk of fractures in the future in patients who suffer from either osteopenia or osteoporosis.

HGH Treatments Have Low Incidence of Major Side-Effects

In studies regarding HGH Hormone Replacement Therapy for the Treatment of Male Osteoporosis, only minor side-effects were reported, and the vast majority of patients did not suspend treatment as a result of the therapy.

For female patients, there is a high likelihood that HGH Hormone Replacement Therapy will cause Estrogen Replacement for Osteoporosis to fall out of favor. For men, on the other hand, it appears that a combination of HGH and Testosterone HRT may produce the best outcomes in regard to both Osteoporosis and overall life quality.

Bisphosphonates are medications that have the ability to slow down the rate at which bones are broken down by osteoclasts, inhibiting the resorption of bone tissue. By slowing down the effect of resorption, Bisphosphonates are able to stabilize the process of Bone Remodeling in order to increase the structural strength of the bones, decreasing the dangers of Osteoporosis. These medicines have been proven to boost bone mineral density while also lowering the incidence of fractures of the spinal cord and the hip.

For post-menopausal females, the Food and Drug Administration-approved Bisphosphonate medication is known as Alendronate. Bisphosphonates produce a few side effects, the most constant being gastrointestinal discomfort and acid reflux. These issues can be resolved by making sure to take the medication without food and with an entire glass of water. Also, remain sitting or standing for a half hour after taking the medication in order to prevent stomach discomfort.

Atrial Fibrillation and Bisphosphonates

Another more dangerous side effect which is believed to result from the usage of Bisphosphonates is atrial fibrillation. It is believed that around one in every thirty cases of atrial fibrillation is the result of the use of Bisphosphonates. Female patients who are particularly at risk for cardiovascular disease, heart attacks, or diabetes should only use this drug at the recommendation of their physician while considering cost-benefit analysis.

Bisphosphonates and Femur Fractures

In very rare cases, femoral fractures can result from Bisphosphonate Therapy, but this occurs in fewer than 1 per 1000 cases, and the benefits exceedingly outweigh the risk of this issue. The reason why it is believed that this occurs is that long term suppression of Bone Remodeling prevents the femur from recovering from minor structural issues. This drug has the ability to break down osteoclasts, and as a result, the bone is not broken down for recycling by osteoclasts and bone structural integrity very slowly declines. Over time in this minority of cases, this leads microfractures to combine into large and more fragile areas prone to more significant fracture.


This form of therapy is a potential course of advantage for females who are not able to utilize Estrogen HRT or other forms of Hormone Replacement. Calcitonin can be prescribed for female patients that passed through menopause a minimum of five years prior to prescription. For these women, Calcitonin can be used to raise the density of the spinal column while reducing bone mass atrophy. Calcitonin (also known as thyrocalcitonin) is a thyroid hormone which promotes stronger bones by helping maintain healthy metabolism of phosphorus and calcium.

Because Calcitonin is a complex hormonal protein, it cannot be taken orally. The hormone would be broken down by the liver before it had the opportunity to function, because of its structure. Calcitonin can be delivered either as a nasal spray which is absorbed into the sinus membrane or as a Calcitonin Shot. Calcitonin inhibits the function of Osteoclasts, reducing the rate at which Bone Resorption takes place while also having a beneficial effect on cartilage formation.

Selective Estrogen-Receptor Modulators

These medicines and molecules have the ability emulate the function of Estrogen on certain Estrogen Receptors. Different forms of SERM medications have the ability to mimic different aspects of Hormonal Estrogen dependent upon their structure. Three common forms of SERM used for treatment of Osteoporosis are Femarelle, Lasofoxifene, and Raloxifene. These drugs can also be used to resolve other issues, included but not limited to Menopause Management, Breast Cancer, and Contraception.

Raloxifene Best SERM for Osteoporosis

Raloxifene has been shown to be particularly effective at resolving Osteopenia and Osteoporosis issues in the spinal column and the hips. For this reason, the drug has been FDA-approved as the most effective SERM in regard to bone health and Osteoporosis prevention. Although the drug does benefit the skeletal system, current evidence shows that Raloxifene is less effective at alleviating and preventing spinal osteoporosis than either Calcitonin, Estrogen Replacement Therapy (for women), and Testosterone Replacement Therapy (for men).

One of the most significant benefits of this drug is that side-effects are incredibly rare, so the drug can be incredibly beneficial for patients who are not able to utilize Hormone Replacement Therapy or Calcitonin treatment. A very small minority of female patients have reported hot flashes similar to those experienced during menopause. An even smaller subset reported Deep Vein Thrombosis, which is a potentially dangerous blood clot in the leg.

Conclusion: Osteoporosis and Hormone Replacement Therapy

There are a number of remedies that can be used in order to prevent or alleviate the symptoms of Osteoporosis. Although many different options provide their own benefits and potential drawbacks, Hormone Replacement Therapy is often the most effective form of treatment.

Benefits of Estrogen Replacement Therapy

Estrogen Replacement Therapy can be very beneficial for short to intermediate-term treatment of Female Osteoporosis. In addition to this, Estrogen HRT has also been shown to provide these other benefits as well:

  • Alleviating the effects of Menopause, reducing the severity of hot sweats and cold flashes

  • Improves mood stability after menopause

  • Decreases incidence of insomnia and sleeping disorders in post-menopausal patients

  • Produces healthier skin by increasing collagen levels in the outer layers, smoothing wrinkles and tightening the muscles of the face

  • Alleviates the symptoms of Peri-menopause and Early-Onset Menopause

  • Increases libido and alleviates vaginal dryness during menopause

Because long term use of Estrogen can increase the risk of breast cancer, long term use of Estrogen Replacement Therapy is not usually recommended, but Estrogen Replacement Therapy utilized in the years of menopause can delay the symptoms of Osteoporosis by preserving bone health. The risks in utilizing Estrogen HRT are very low when used for a relatively short period of time, but utilizing the treatment for ten or more years may lead to unacceptable breast cancer risk. In the future, these recommendations may change significantly, because newer research suggests that Estrogen Replacement Therapy can be effective at maintaining bone health even at very low doses which do not significantly increase the risk of breast cancer.

Benefits of Testosterone Replacement Therapy

Testosterone HRT is one of the most talked about Hormone Treatments available in the United States today. Although the body of research is not as large as that for Estrogen Hormone Replacement, there is significant evidence that Testosterone HRT can be highly beneficial for male patients at risk or experiencing Osteoporosis or Low Bone Density. Hormone Replacement Therapy with Testosterone produces a number of other benefits which can make Osteoporosis prevention seem like an added bonus. The following are common benefits of Testosterone Replacement Treatments:

  • Increases in libido

  • Resolves sexual dysfunction and alleviates premature ejaculation

  • Boosts and/or preserves muscle mass

  • Enhances cognition and memory faculties

  • Prevents depression and stabilizes mood while suppressing anxiety

  • Alleviates pain in the joints and muscles

  • Increases energy and reduces feelings of exhaustion

  • Raises ones overall sense of well-being

There are some side-effects associated with Testosterone Injections, patches, and creams, but for patients who utilize low-dose Testosterone treatments for Testosterone Deficiency, major side-effects are incredibly rare, and the vast majority of patients either experience no side effects or minor side effects. It is estimated that Testosterone Replacement Therapy for Low-T can actively benefit half of men in their fifties. For men in their sixties, the number is estimated to be even highersixty percent! As the body of knowledge surrounding Testosterone as an Anti-Aging Therapy grows, it is inevitably that new and perhaps greater benefits will also be revealed as well.

Benefits of Human Growth Hormone Replacement Therapy

HGH Hormone Replacement Therapy has only been studied as a potential treatment for Osteoporosis in recent years, but the benefits seem to show high levels of potential. HGH proves time and time again that it is a vital hormone which greatly alleviates the negative aspects of the aging process while preserving optimal function and metabolism in multiple systems of the body. We may eventually find that HGH plays at least some role in every single important process of the body. Dr. Wusters recent Human Growth Hormone for Osteoporosis study shows that HGH has the ability to increase bone density as a result of the positive interaction that takes place between HGH, IGF-1, and the osteoblast. This form of therapy seems equally beneficial for both men and women. This treatment is also likely safer and provides similar benefits to Estrogen Replacement Therapy for Osteoporosis without producing the side-effect of increased cancer risk.

HGH Shots also provide a number of other significant benefits in addition to the prevention of Osteoporosis, including, but not limited to:

  • Increased metabolism

  • Breakdown of unhealthy adipose fat tissue

  • Increase in muscle mass and strength

  • Improved sleeping habits

  • Boosted nutrient absorption

  • Enhanced Energy

  • Reduced Fatigue

  • Increase overall sense of well-being

Although there is a certain risk for side-effects when using Human Growth Hormone, these risks are generally associated with individuals who abuse the drug for the purpose of performance enhancement. HGH is not legal for use as a PED in the United States, and can only be used by those who have a diagnosable Human Growth Hormone Deficiency or other legitimate medical condition such as Hypopituitarism or Childhood Idiopathic Short Stature.

The Conscious Evolution Institute

The Conscious Evolution Institute is one of the nations leading Anti-Aging and Regenerative clinics. Osteoporosis is one of the most devastating conditions related to the aging process. Sadly, if more men and women were proactive, the disorder would be much less prominent than it is today. There are many ways to treat the disease, and for many individuals, Hormone Replacement Therapy with Testosterone, Estrogen, or HGH may be the right answer.

We urge you to give us a call today if you are feeling the effects of Hormone Deficiency. There is no pressure to commit, and we have a friendly, knowledgeable, and experienced staff that will be happy to take the time to answer any questions you may have about our treatment options. At the Conscious Evolution Institute, we work with you to create a life plan that will help you maximize the benefits of Hormone Replacement. Its not just a medical treatment, its a lifestyle revolution. In addition to your Hormone Medications, we will also work with you to design a work out and nutrition plan that will help you get into shape. We have helped thousands of men and women all across the United States alleviate and reverse the effects of aging and we want to help you as well.

National Network of Conscious Evolution Institute Affiliates

If you are interested in the treatments we provide, please fill out the form on our website or call our toll-free number today. We have a certified network of affiliated physicians all across the United States, so there is no need to visit us in person. Our affiliates gather all the necessary data we need in order to provide an accurate diagnosis, including Family History, Blood Sample, and Routine Physical. After we receive your diagnostic data, we will have everything we need to make an accurate diagnosis. You will receive your diagnosis in around five business daysNo need to wait! After we fill out your prescription, we can ship the product via FedEx straight to your door. Its just that easy. Again, we encourage you to call us today at the Conscious Evolution Clinic. Dont put it off any longer. If you are over the age of thirty and feeling the adverse effects of the aging process, we can help! We look forward to hearing from you.

Yours in Longevity,

The Conscious Evolution Institute

06 February 2013

My Own experience with Human Growth Hormone (case study)

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Human Growth Hormone Testimonial

There are tens of thousands of individuals all across the world that has utilized Growth Hormone Replacement Therapy as an anti-aging therapy. The following is an HGH Success Story provided by a retired physician who recently turned eighty years old:

I have seen amazing results from my experience with Human Growth Hormone HRT. My physicians name is Doctor Cranton, and I entirely have him to thank. Growth Hormone Shots have completely changed my life for the better. The HGH injections have literally turned back the clock for me

Testimonial: Before HGH

On a normal morning, before I began to use Human Growth Hormone, I would rise from bed with nagging aches and pains throughout my body which caused me an immense amount of grief. My muscles hurt when I stretched. My bones pulsed with pain and my joints were practically creaking. Even my skin throbbed when I closed my hands into a fist or smiled too large. Its quite obvious that all of this had a profound effect on my life.

For the first time in my life, I was starting to feel like I was no longer able to take care of myself. I was almost ready to give up altogether and resign my body to a wheelchair. The back pain was becoming inescapable and with each step the pain shot straight from my spine down to my legs. Over the past fifteen years I was forced to undergo surgery to correct debilitating back issues. Five years ago I even had to undergo spinal fusion in order to make my life bearable. Before I started using HGH Shots, the agonizing pain I experienced in my spine forced me to walk with a bent back in order to minimize the agony. Even pain medicines didnt help. I was nearing the end of my rope.

But Then I Tried HGH.

The changes began to occur relatively quickly after I began to use BioIdentical Growth Hormone injections. A few months after I began to take the Anti-Aging Hormone, I began to arise from bed in a much different manner. Where just months earlier I woke up in great amounts of pain, I now found that I could wake up comfortably with little to no lingering pain. Its amazing how much such a small thing can improve ones life so immensely.

The pain was practically gone.

No More Pain with HGH

Just rolling out of bed without wincing was enough to put a smile on my face. Because of Human Growth Hormone Injectable Therapy, The dark cloud that hung over my life dissipated. For years I suffered from the symptoms of anxiety, dysthymia, and depression as a result of my limited physical abilities. Injectable Growth Hormone literally helped me hold my head higher. HGH relieved the pain and rehabilitated my body to the extent that I could straighten my spine far more than I could before I began therapy.

HGH Reduces the Need for Other Medications

Also, Human Growth Hormone greatly reduced my need for other medications that I had begun to take as a result of the aging process. I used to keep a seven day pill organizer with me at all times. HGH Hormone Treatments have benefitted me to such an extent that I now only use a few very particular medications in order to further preserve my health.

Ive even taken up my favorite past time for the first time in years and yearsgolf. Ive always been a decent golfer, and I was recently able to shoot a forty on a nearby 9-hole course. I cant even remember the last time I shot that well. And thinka couple of years ago I couldnt even swing a club without keeling over in great pain.

Alternatives to HGH Failed Me

I tried a number of different therapies before I finally tried Bio-Identical HGH injections. There are a lot of other forms of HGH which purport to induce the same great benefits provided by HGH shots. I first attempted to use two forms of Growth Hormone Spray, but they provided me little benefit.

After that experiment, I attempted to use a few other HGH alternatives such as ornithine, arginine, and glutamine amino acid in an attempt to supplementally boost my Endogenous Growth Hormone Levels. These amino acid supplements did absolutely nothing for me.

Finally, I met Doctor Cranton, who finally convinced me to try Human Growth Hormone Injections, and I feel that I can never repay him for the way that he restored my life with his prescription.

Over the course of the next couple of weeks I followed my doctors prescription to a T. The improvements began to mount and the pain really started to go away. I eventually got brave enough to convince my son to go out with me to play a half-round of golf. I made it through easily, although I did experience moderate pain over the course of the next two days as a result.

Always Complete Your HGH Cycle

A few days later, after the pain had went away, I felt so great that I felt that I could quit taking the injectionsthis was a mistake. Apparently, the effects of HGH take a few months to fully set in and my body reverted back to its former state of pain as a result. Over the next couple of weeks I was back to barely being able to get out of bed.

Doctor Cranton scolded me gently and encouraged me to restart the therapy and I readily obliged. From this point on I consistently took one dose of Human Growth Hormone every day and all of the benefits that I received initially from the therapy returned and were even enhanced with continued therapy.

HGH Changed My Life

I am 100 percent sure that the changes in my life were the direct result of Human Growth Hormone Injectable Therapy, because I made no serious changes to my life other than initiating HGH Shots. Earlier this week, I played a full round of golf and experienced no abnormal pain as a result of my exertion. Its like taking the chains off of your life.

Use HGH to Avoid Surgery

Growth Hormone even helped me avoid a major surgery which I suspected would be unavoidable. A few months before I began HGH Treatments, I had to visit an orthopedic surgeon because I was experiencing near-debilitating pain in my knee. He said that it was the result of worn cartilage and that I would most likely need my knee entirely replaced. The pain and swelling were severe and my knee was no longer able to engage in a full range of motion because of the pain. I was supposed to go under the knife that fall. Luckily, I was able to avoid this because of Human Growth Hormone Anti-Aging Treatments. A combination of HGH Shots and nutritional supplementation provided so much relief that my knee was nearly resolved of all pain.

At my age, any surgery is risky, so I am much indebted to my physician. If you want to experience the same amazing benefits as I do and want to cure HGH Deficiency, I urge you to talk to an experienced physician. It really can change your life. Just look at me!


Dramatic changes such as these occur in individuals who have very low Endogenous Human Growth Hormone Levels. Patients who have IGF-1 levels under 100 are considered severely deficient. If your IGF-1 levels are below 50, you may experience even more profound results.

Rejuvenate and Restore Your Life with HGH

Human Growth Hormone has genuine and incredible rejuvenative properties. Dr. JBM benefitted in a number of ways, and his testimonial demonstrates a number of common benefits of the natural HGH Hormone.

Mood Elevation with HGH

Dr. JBM said that his depression and anxiety were resolved with HGH. There are two primary reasons why this occurs. One reason that depression is alleviated as a result of HGH is because the patient recognizes the physical and cognitive benefits of Human Growth Hormone and feels better about life as a result.

Many of the core reasons depression occurs are environmental. Its hard to live a happy life when constant pain and physical disability prevent you from living your life to its maximum potential. As these symptoms are cured or softened, it makes it easier to see the bright side of life.

The second reason that depression is resolved using HGH Shots is due to genuine changes that occur in brain chemistry and hormone distribution that physiologically make it easier to be happy. In a 1996 study, over 900 participants utilized Human Growth Hormone in order to demonstrate the effects of the treatment. 67% of the patients in this study reported that they experienced greater emotional health as a result of HGH Injections. An even greater percentage, 80%, responded that Human Growth Hormone was able to improve their overall wellbeing and attitude about life.

Physical Rejuvenation with HGH

HGH and Cartilage Regeneration

Another benefit that Dr. JBM reported was that the pain in his knee went away over the course of his therapy. One of the primary benefits of HGH is that it increases the bodys overall metabolism and rate of physical rehabilitation. Although we often think of the bones as strong and inactive organs, they are actually constantly going through a process of renewal known as remodeling.

HGH and IGF1 play an integral role in the upkeep and development of the bones, and HGH Deficiency can be devastating in regard to bone health. There is some convincing evidence that Human Growth Hormone has the ability to rebuild cartilage in the joints in a similar manner as it does in the spongy and hard bone that supports it.

Human Growth HormoneMuscle and Tendon Health

Another reason that Dr. JBM felt less pain is because of the effect that Growth Hormone has upon the structure of the muscles and tendons of the body. One major reason why people experience joint pain is not because of the joint itself but because of the support system surrounding it. When the tendons and muscles are not strong enough to support the weight of the body efficiently, this increases stress upon the joints. In cases like Dr. JBMs where the joints have worn and cartilage is significantly damaged, muscle and tendon issues can greatly magnify the pain caused by undo pressure on the joints.

Human Growth Hormone and IGF-1 cause the body to naturally grow more muscle. As a result of this, the body is able to support itself more effectively which reduces stress upon the joints. This is likely another reason why Dr. JBM no longer needed surgery after initiating HGH Hormone Replacement Treatments.

HGH and Back Pain

Dr. JMB also reported that HGH Replacement Therapy alleviated his back pain. There is a significant amount of anecdotal evidence that corroborates his case. For individuals who suffer from back pain as a result of damaged vertebrae or spinal disc surgery, Human Growth Hormone Injection Therapy can increase the structural strength of existing bone while also greatly reducing pain.

One of the primary ways that Human Growth Hormone relieves back pain is through a process known as spinal rehydration, also known as spinal decompression. HGH helps hydrate the area between the spinal discs, reducing pain in the same way that it resolves joint pain.

When the spinal column is dehydrated, the cartilage between the bones grinds against one another, damaging the soft bone tissue and creating significant pain over time. Dr. JMB was most likely able to hold his back up straighter because of the spinal rehydration that occurred as a result of Human Growth Hormone Replacement Therapy. After the process of rehydration occurs, the bones are no longer under such immense pressure and the cartilage can go through the slow process of rebuilding.

When should I start HGH Replacement Therapy?

Although BioIdentical Growth Hormone produces amazing results for men and women in their seventies and eighties, there is no reason to wait so long to initiate therapy. By the time that we reach our thirties, Endogenous HGH levels start to decline at a steady yet insidious rate of around one percent each year.

Although this might not seem like all that much at first glance, over the course of multiple years and decades the effects of HGH deficiency are devastating. Human Growth Hormone can be used as a form of preventative medicine to avert the major medical issues that the man in the above testimonial suffered from.

What are the other benefits of Human Growth Hormone?

Dr. JMBs story presents merely a fraction of the benefits that HGH Shots provide. Human Growth Hormone HRT can also:

  • Strengthen the Muscles

  • Improve Cholesterol Levels

  • Increase Physical Endurance

  • Boost Memory

  • Enhance Weight Loss Outcomes

  • Increase Sex Drive and Resolve Sexual Performance Issues

How do I get a prescription for HGH?

If you are interested in the benefits that Human Growth Hormone can provide, the Anti-Aging Doctors at the Conscious Evolution Institute are here to help. If you have any questions, feel free to contact us online or by phone on any business day!

The Conscious Evolution Institute provides the highest quality HGH Hormone Treatments as well as other therapies such as Testosterone HRT, Sermorelin Acetate Therapy, and HCG Weight Loss Treatments.

Take the first step today. We look forward to hearing from you!

The Conscious Evolution Institute

13 February 2013

Testosterone Enanthate

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Testosterone Enanthate

What Is Testosterone Enanthate?

Testosterone Enanthate is among the most popularly prescribed Testosterone Therapy Treatments in the world. For better or worse, it is also popular among those that use Testosterone for Performance enhancement. Testosterone Enanthate is one of the cheapest forms of Testosterone Therapy available, while also being one of the most effective and safest. Most men with Low-T have minimal issues with Testosterone Enanthate Treatment.

Testosterone Enanthate Composition

Like most Testosterone Injections, Testosterone Enanthate is a Carboxylic Acid Ester Compound. Esters are attached to Testosterone molecules to form a medical compound which slowly releases Testosterone into the blood stream over time. The more esters that a Testosterone Molecule has, the longer that a single injection provides Testosterone. Both the Testosterone and the Ester compound are synthetically derived. Testosterone is produced in a laboratory environment, and is 100% identical to that which is produced by the human body.

As the Testosterone Ester degrades, this slowly provides a stream of Free Testosterone to meet the body's needs. As with all Testosterone Esters, there is a general pattern in which Testosterone Levels ebb and flow. After Testosterone Enanthate is injected, the body receives a surge in Testosterone, generally at some point one full day to two days after injection. After 48 hours or so, Testosterone Levels balance out and begin to slowly drop, necessitating an injection every seven to ten days for maximum stability, though some doctors may recommend up to a 14 day schedule for certain patients.

How to Inject Testosterone Enanthate

Testosterone Enanthate is delivered via intramuscular injection, as are most other forms of Testosterone Replacement Injection Therapy. Before delivering the injection, you may be required to reconstitute the Testosterone Enanthate, saturating the lyophilized powder so that it can be injected into the body. After the Testosterone Therapy is reconstituted, it is then delivered into muscle tissue. Most Low-T Injections are a combination of a Testosterone Ester and an oil solution. Upon injection, the ester compound slowly breaks down, providing a steady stream of Testosterone which enters the blood stream.

Testosterone Enanthate Benefits

Testosterone Enanthate provides the same great benefits as any other form of Recombinant Low-T Therapy. Testosterone Enanthate is highly effective at treating the symptoms of most forms of Testosterone Deficiency, and is popular for the treatment of Andropause, also known as Age-Related Low-T. For men suffering from Testosterone Deficiency, Testosterone Enanthate has the ability to increase muscle mass, improve mood, enhance sexual desire, and more. Many patients even experience improved sleeping habits. There is even some evidence that suggests, when used as directed, Testosterone Therapy can be beneficial to cardiovascular health in patients with legitimate Low-T.

Testosterone Enanthate Results

Testosterone Enanthate is one of the most popular forms of Andropause Therapy because it works and requires injections only once every week to two weeks. Most patients suffering from Andropause or Idiopathic Testosterone Deficiency experience significant results in a matter of months. As with Human Growth Hormone Therapy, you should expect to experience a modest accrual of benefits culminating over the course of around six months. If you combine your HRT Therapy with a strong diet and exercise plan, you'll experience the best possible results. Testosterone Enanthate is a quality means to improve and sustain Testosterone Levels.

Testosterone Enanthate Risks and Side-Effects

Like any form of Testosterone Therapy, Testosterone Enanthate does carry a risk of side-effects. The most common side-effect of Testosterone Therapy is suppressed natural Testosterone Production. The body recognizes that Testosterone Levels are in the healthy range, and signal for lower Luteinizing Hormone and Follicle-Stimulating Hormone Production. This both reduces natural secretion of Testosterone by the testes and adrenal glands, and it impairs sperm production. Another common side-effect of Testosterone Treatment is reduced fertility, due to this suppressed sperm production. Using HCG Injections can help support both natural Testosterone Production and promote fertility during Testosterone HRT.

Other less common symptoms include increased risk of blood clots, gynecomastia (breast enlargement), increased prostate size, mild water retention, and acne. When used as directed for the treatment of a legitimate deficiency, these symptoms are much more rare. When Testosterone is abused, the risk of these symptoms increases significantly.

Testosterone Enanthate vs Testosterone Cypionate

These are the two most commonly used forms of Testosterone Injection, both for legitimate HRT Use and for Performance Enhancement (we do not condone the use of Testosterone without a legal prescription). Like most forms of Testosterone Injection, the primary difference between the two HRT Injections has to do with their half-lives. Testosterone Cypionate stays in the blood stream longer, owing to its larger ester-chain (seven carbons for enanthate, eight carbons for cypionate).

Whereas Testosterone Enanthate reaches its half-life in around ten and a half days, Testosterone Cypionate does so in about 12 days. Patients that opt for biweekly injections may be more interested in Testosterone Cypionate, but both are quality forms of HRT Treatment. Enanthate has a wider market-reach in Europe, whereas Cypionate is more widely available in the United States, so this is also a factor.

Testosterone Enanthate vs. Testosterone Propionate

Testosterone Propionate was the first intramuscular Testosterone Injection ever produced, and is the precursor for all that followed it. Testosterone Propionate only has one ester, compared to the seven-ester Enanthate. Testosterone Enanthate is rarely used for Hormone Replacement Therapy, because it requires an injection every 1-3 days, which is too much for most people when other alternatives are available. Testosterone Propionate has found a niche in the bodybuilding community, however.

Testosterone Enanthate Injections Vs. Other Forms of Testosterone

Testosterone Injections are just one of many forms of Testosterone Replacement Therapy, all of which are highly effective at treating the symptoms of Age-Related Testosterone Deficiency and other forms of Low-T. Other common forms of Testosterone Treatment include Testosterone Creams, Low-T Patches, and Implanted Testosterone Pellets.

Testosterone Creams are applied topically to the skin, making them a relatively low-fuss way to use Testosterone Therapy. Of course, these creams require daily applications, whereas Low-T Enanthate Injections only require an injection every seven to ten days, making it less of a hassle to remember each day.

Testosterone Injections do have a slight pain associated with them, which may be a factor in whether you are interested in Testosterone Enanthate, though there are products which are designed to mitigate the mild pain associated with injections, and most patients consider it nothing more than a mild discomfort.

Testosterone Patches are similar to Low-T Gels in that they are applied daily, but Patches are adhered to the skin in the morning and taken off daily, providing a slow leech of Testosterone through the skin for the entire day. Testosterone Injections have an advantage over Low-T Patches and Creams in that there is a risk of washing off the patch or cream when swimming or performing other activities in water. Patches are fairly resilient, but you still have to be careful. Water is only an issue for Testosterone creams for a brief period after application, however.

Testosterone Implantation is the only form of Testosterone Therapy that lasts longer than Testosterone Injections, but Testosterone Implants are the most invasive form of Low-T Treatment. Testosterone Pellets are surgically inserted under the skin, usually in an outpatient setting. The surgery doesn't take long, and the pellets provide a stream of Testosterone which lasts for three to four months. Of course, Low-T Implants are more expensive than other forms of therapy for this reason, so most patients that are interested in a more long-term approach still usually opt for Testosterone Enanthate and other similar Testosterone Injection formulations.

Where can I Find Testosterone Enanthate?

If you are interested in Testosterone Enanthate for Low-T, understand that it is easy to acquireif you have a prescription. We strongly discourage anyone from using Testosterone Injections or any other form of Testosterone Therapy without a prescription from a licensed and reputable medical professional. There are also Testosterone Therapy clinics located all across the United States that can help you find out if you suffer from Low-T, and if you are eligible for Testosterone Replacement Therapy, or any other form of HRT Treatment. If you'd like to learn more about Testosterone Therapy, we encourage you to contact us for more information.

Find a Testosterone Doctor in Your Area

Are you interested in Testosterone Enanthate, or any other form of Bio-Identical Testosterone for Low-T? If so, we can help you get the treatment that you deserve. We represent a Licensed and Board-Certified Hormone Therapy Center that specializes in serving men and women thirty years and older all across America. Testosterone has helped hundreds of thousands of men across the country experience increased vitality, virility, and quality of life, and we would love to help you experience the same! Our highly qualified clinical HRT staff is just a phone call away. Also, feel free to fill out the form that you see on this page to set up a preliminary phone consultation!

25 February 2018

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Testosterone Therapy Benefits

Correctly performed testosterone therapy can be your ticket to health.

Three sided solution: Testosterone + HCG + Arimidex

If your doctor only prescribes testosterone by itself, you will probably have a rough ride. The tendency is for you to feel great the first couple months, while you increase testosterone levels, followed by a slow deterioration, once your estrogen creeps up.

High estrogen negates a lot of the positives from testosterone therapy, resulting in the same symptoms of low testosterone you had in the first place!

The solution is to add a drug called Arimidex. It's called an aromatase inhibitor, which essentially blocks the conversion of testosterone to estrogen. It has the effect of increasing testosterone levels, while keeping your estrogen low.

Once you have your testosterone and estrogen solved, it's time to stop the next inevitable decline? Shrinking testicles.

This is where HCG (human chorionic gonadotropin) comes in. It prevents both infertility and testicle shrinkage. Your testicles shrink because your body thinks it doesn't need to make testosterone anymore.

For some, small testicles may seem like just a cosmetic problem. But HGC does more than increase testicle size, it also increases adrenal function, which can have positive effects on well-being, libido, and energy.

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