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Does
Growth Hormone Have Anti-Aging Properties?
It is quite
true that we are all going to get old. As a matter of fact, the
generation of baby boomers is quickly approaching their
mid-fifties, and the number of elderly people in America will
continue to increase for another generation. Why then, do we have
to resign to growing old in the same way that previous generations
were forced to in the ages before us? Must we be weak, frail,
fatigued, depressed? Living in fear to take a walk in the park for
fear that we may fall?
It is a
truism that youth is wasted on those who are young. If such a
saying is true, why should the opposite statement also be true? Why
must wealth and experience be wasted upon those that are old?
Should not older men and women be able to retain their enthusiasm
and energy in a grand effort to enjoy their autumn years?
We do not
have to take age lying down! We here at the Conscious Evolution Medical Institute have
learned that old age is largely a state of mind that has been
induced by hormonal deficiencies. It is a state in which the
hormones we so enjoyed in our youth have become less bountiful. It
makes logical sense that with hrt hormone replacement therapy many
of these symptoms can be alleviated or reversed.
One of the
most impressive hormones that can be regained through Bio identical
Hormone Replacement therapy is Human Growth Hormone. It can allow
an older woman or gentleman to live a healthier, longer, and more
active life. The greatest point to be made about Human Growth
Hormone is that it truly is not all that fantastic of a concept.
Growth Hormone is naturally produced by the body, and it is
produced in large quantities when we are in our youth. The longer
we can retain Growth Hormone, the more we can slow down many of the
devastating effects of aging.
It makes
perfect sense. Growth Hormone is vital to growth processes within
the body. GH supplement is provided to young children who are
maligned with slow skeletal growth, and it allows them to grow
taller than they would without treatment. The problem is that Human
Growth Hormone levels drop at a steady rate in all men and women
after they enter adulthood. After decades of research, we now know
that Human Growth Hormone provides significant benefits throughout
the lifespan. For this reason, we must conclude that Growth Hormone
is vital for the maintenance and rejuvenation of the body in
adulthood. Research regarding the effect of Growth HRT upon elderly
patients provides evidence that the main role of the hormone in
adulthood is to allow one to live a longer, healthier life of
higher quality.
Where
does Human Growth Hormone Originate?
Human
Growth Hormone is produced in the anterior area of the pituitary
gland which is buried deep within the brain. Human Growth Homrone
is a microscopic protein molecule. It has chemical similarities
with insulin, though HGH is secreted in brief, sharp pulses after a
person exercises or in the initial hours of rest. Human Growth
Hormone only stays in the blood stream for a few minutes. For this
reason, it in incredibly difficult to measure Human Growth Hormone
in serum. Though it does not remain in the blood stream for long,
HGH binds to the liver which turns some of the hormone into
Somatomedin-C, which is also known well by the name Insulin-Like
Growth Factor I (IGF-1) Since IGF-I stays in the blood for up to
one and a half days, a blood sample that contains IGF-I proves that
HGH is being produced. Normal IGF-I levels in the blood tend to
appear in volumes of 200 to 450 ng/ml. However, one third of men
and women that are over the age of fifty display levels of HGH that
are lower than 200 ng/ml. During puberty, Human Growth Hormone
levels are at their peak and IGF-I reaches levels of 600-800 ng/ml
or even higher. In normal women and men under the age of forty,
less than five percent have levels of HGH that are below 250 ng/ml!
After the age of 40 many women and men have a level of Human Growth
Hormone that is similar to that of an octogenarian! Human Growth
Hormone may be the means by which we can age gracefully.
When IGF-I
levels drop under the baseline adult range, energy levels and bone
and muscle strength tend to decrease as well. Cell regrowth, tissue
repair, vital organ repair, general rejuvenative ability, enzyme
production, and hair, skin, and nail revitalization will begin to
occur less effectively
Though
decreased levels of Human Growth Hormone and increased age are
certainly directly correlated, those who lose full function of the
pituitary gland, whether through accident, infection, or surgery,
will immediately begin to be maligned with acute ill effects.
It is
vital to understand that natural HGH will inevitably decline with
age!
In those
who are utterly lacking a functional pituitary, body composition
changes and a shift occurs where the amount of fat increases by
7-25%. Lean mass of the body decreases at a similar rate. Mass and
strength of the muscles diminish as well. Studies in regard to bone
density show that in those patients with no pituitary input, it
seems as though an individual ages by around 15 years by analysis
of the density of both the long bones and the spinal bones. As
Human Growth Hormone flags, weight increases of as much as fifty
pounds occur. Beyond this, there are issues regarding cholesterol
as well. Levels of triglycerides go up, and good HDL cholesterol
suffers. Cardiovascular complications occur more often, which could
be related to the thickening of the vascular walls of the heart.
Decreased output by the heart leads to further problems.
Hormonal
insufficiencies such as these often lead to people such as these to
report a serious decline in their capacity to exercise, and they
often suffer from cardiovascular disease, which leads to early
mortality. Also, they report issues with loneliness, depression,
focus, and fatigue. In general, they just suffer from a general
lack of well-being.
Hope on
the Horizon: Food and Drug Administration approves Human Growth
Hormone for Use by Adults
Recombinant
HGH has recently gained approval by the FDA for women and men of
adulthood for the therapy of Growth Hormone Deficiency and
hypopituitarism. If a person suffers from hypopituitarism, Human
Growth Hormone therapy is compatible under the majority of
insurance policies. After being approved for therapy, patients are
administered Human Growth Hormone treatment and testing under
professional supervision. Our experience and the revelations of
research provide ample evidence that Human Growth Hormone
Replacement Therapy offers benefits to those that have insufficient
levels of Growth Hormone. This deficiency is often referred to as
Somatotropin Deficiency Syndrome. The Conscious Evolution Medical Institute also provides
Human Growth Hormone treatment for patients who suffer from
Somatomedin-C (Insulin-Like Growth Factor-1) levels under 200 ng/ml
that are approved in our Internal Review Board registry, but these
patients are required to pay for their treatment.
Please
realize that by undergoing a global hormone replacement regimen,
administering progesterone, estrogen, testosterone, thyroid,
pregnenolone, or DHEA (other vital hormones which a patient may be
co-deficient) when necessary in addition to Human Growth Hormone,
one can minimize the costs, side-effects, and dosage of
treatment.
Growth
Hormone Replacement Therapy Changes
Administration of Human Growth Hormone often leads to substantial
changes in the composition of the body: lean muscle mass increases
as fat mass percentage is reduced. Using Human Growth Hormone at
the modest dosage of 0.003 mg/kg over the course of six months was
shown to improve lean muscle mass in 24 patients that had a Human
Growth Hormone deficiency (1). Improvements in lean muscle mass
have been associated with higher levels of protein synthesis, along
with muscle function and mass. The percentage of body fat also
drops after six months of Human Growth Hormone administration. The
most fat is eliminated from the areas of the trunk and the stomach,
rather than the legs, neck, and arms. This fact is evidence that
Human Growth Hormone replacement treatment can reverse excess
stomach fat associated with Human Growth Hormone deficiency, along
with reducing risks of heart problems.
Heart
Health and Metabolism of Cholesterols
Human
Growth Hormone Therapy for adults also shows is believed to have a
positive effect upon cholesterol. In new research, it has been
shown that brief regimens of Human Growth Hormone Therapy led to
reduced LDL (or bad) cholesterol (7) while also boosting heart
function and capacity for exercise. Participants showed higher
levels of oxygen intake as well as strength during cycling
exercise. Human Growth Hormone has been associated with higher
levels of muscle mass and stronger and longer action upon the
treadmill (8). Recent research by Fazio has shown that those who
have experienced heart failure have shown improvement after being
given high dosage of Human Growth Hormone Therapy.
Bone
Density
Among the
most stunning effects of Human Growth Hormone is its effect upon
the skeletal system, muscles, and tissues. It provides a
significant level of rejuvenation to these systems. Skin health
improves, damaged bones heal more effectively, and significant
levels of improved muscular strength have been reported during
Human Growth Hormone Therapy. Others have reported that signs of
aging are fading from their skin. Sometimes hair regrowth occurs in
male hormone replacement therapy patients as well as female
patients. These changes provide evidence that testosterone, DHEA,
and Human Growth Hormone are anabolic (synthesizing) hormones that
significantly rehabilitate tissue of the body. Unfortunately, as we
age, catabolic processes lead to faster levels of tissue breakdown.
Human Growth Hormone combats the catabolic processes of aging.
The most
significant way that Human Growth Hormone effects the skeletal
system is through its role in enhancing the body's ability to build
and repair the bones. Human Growth Hormone stimulates the
proliferation of fibroblast (ligament) and osteoblast (bone) cells
in the skeletal system. In recent clinical research using the
powerful techniques of single photon absorptiometry and
quantitative tomography, marked increases of 4% and 5% were shown
in cortical and spinal bone density over the course of twelve
months of therapy in adults deficient in Human Growth Hormone (4).
In conclusion, it seems that the administration of Human Growth
Hormone may lead to an enhancement of multiple organ systems of the
body through the positive effect it has upon the skeletal
system.
More
examples of Human Growth Hormone's anabolic effects include muscle
gain and increased appetite, increased capacity for exercise,
increased capacity of the lungs, and increased would
rehabilitation. Many also report that liver spots, also known as
senile keratoses, begin to fade after eight weeks of Human Growth
Hormone Therapy.
Side-Effects of Low Dosage Human Growth Identical Hormone
Replacement Therapy.
Human
Growth Hormone dosage is a vital consideration in those who suffer
from Human Growth Hormone Deficiency. Overdosage of Human Growth
hormone is associated wit many signs of excess Human Growth
Hormone. Among these symptoms are hypertension, carpal tunnel, and
excess fluid retention. However, by using more modest doses of
Human Growth Hormone, it was demonstrated by Bengtsson that only
mild side-effects such as slight joint pain and mold fluid
retention occur. Only a single case of carpal tunnel was
discovered. In each of these cases, further restriction of the
Human Growth Hormone dose lead to full elimination of the
side-effects. Another clinical study only used a small dose of 0.01
mg/kg, which was injected three times each week. In this study,
there were zero side-effects reported (8). Many studies provide
evidence that says that low dosage Human Growth Identical Hormone
replacement therapy generally only causes modest side-effects, if
any.
Benefits
of Hormone Replacement Therapy with HGH.
Improve
Body Composition: Boost muscle mass and reduce fat for a shift in
body composition of as much as 20 pounds. This change can lead to
higher sex drive, as well as enhanced physical well-being and self
perception.
Improve
Energy: Human Growth Hormone patients report higher levels of
energy without the need for afternoon snacks, stimulants, caffeine,
or cigarettes. This energy boost helps them become more confident
in their self control and enhances their capacity for exercise.
Improve
Focus: An intriguing yet untested potential benefit of Human Growth
Hormone is a return of mental focus and enhancement of memory.
Since Human Growth Hormone provides improvement to the
intracellular and vascular systems which support the cells, it is
not at all surprising that these benefits have been reported in
individuals.
The
Future
Many
fundamental questions remain regarding the exact medical definition
and preferred treatment for partial versus total Human Growth
Hormone Deficiency. Also, it is not clear whether all of the
realized positive effect of full Human Growth Hormone Replacement
Therapy will occur in those that undergo low dosage or combination
treatments. Even so, is has already been made clear that even small
doses that do not result in potential side-effects sufficient level
may be sufficient for some to reach their metabolic goals. We here
at the Conscious Evolution Medical Institute hope that our continued clinical evaluations
will help lead to more efficient usage of Human Growth Hormone, as
well as help reveal more of this wondrous therapy's benefits while
eliminating incidence of increased cardiovascular and general
morbidity.
Works
Cited
Cuneo,
Salomon, and Hesp, et al. Treatment effects of Recombinant HGH upon
Metabolism and Body Composition among Adults with Growth Hormone
Deficiency. New England Journal of Medicine 1989; Issue 321: Pages
1797-03.
Bengtsson.
Consequences of Growth Hormone Deficiency in Adults. Acta
Endocrinoligica 1993; Volume 128: Pages 2-5.
Cuneo,
Salomon, Wiles et al. Effects of Human Growth Hormone Treatment
Among Adults Whom are Deficient. Applied Physiology Journal 1991;
Volume 70: Pages 695-700.
Halloran,
Tsatsoulis, Whitehouse et al. Increased Bone Density after Human
Growth Hormone Therapy Upon Deficient Adults. Journal of Clinical
Endocrine Metabolism 1993;Volume 76: Pages1344-48.
McGauley,
Cuneo, Salomon et al. Psych. Self-perception changes due to Growth
Hormone Treatment in Adults with Human Growth Hormone Deficiency.
Hormone Research 1990; Volume 33(Supplement 4): Pages 52-54.
Bengtsson,
Eden, Lonn et al. Therapy of Adults with Human Growth Hormone
Deficiency with Recombinant Growth Hormone therapy. Journal of
Clinical Endocrine Metabolism 1993;Volume 76:Pages 309-17.
Johnston,
Bengtsson. Effects of Growth Hormone and its Deficiency upon Heart
and Lipids. Acta Endocrinologica 1993;Volume 128(Supplement
2):Pages 69-70.
Amato,
Carella, Fazio et al. Heart Structure, Metabolism of Bone, and Body
Composition Heart Structure in Growth Hormone-Deficient Adults
Effects of Human Growth Hormone Replacement Therapy at Mild Dosage.
Journal of Clinical Endocrinology and Metabolism. 1993;Volume
77:Pages1671-76.
Fazio,
Sabatini, Capaldo, et.al. Test study of GH in the treatment of
cardiomyopathy. New England Journal of Medicine. 1996;Volume
334:Pages 809-14.
The above
information does not provide sufficient evidence to self-diagnose a
particular procedure or treatment. It should not lead one to
believe that this is the only treatment option available.
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