|
Osteoporosis Guideline: Diagnosis
and Treatment
We hear about the dangers of osteoporosis all of
the time, but we rarely hear the disease explained. From a linguistic
standpoint, Osteoporosis literally means porous bones. The
disease is highly associated with an increased risk of bone breaks
and fractures. As men and women (especially women) grow older, the
risk for severe damage to the hips and spinal column can result. Hip
fractures are one of the single most dangerous breaks that can occur
to the human body, and these fractures are associated with a greatly
increased risk of mortality.
Hip Fractures and Increased
Mortality
A recent study released by the University of
Pennsylvania Medical School shows that women who have recently
experienced a hip fracture have over twice the mortality rate of
female patients who did not. Patients who did not experience these
fractures had an annual mortality rate of 8.4%, whereas those who
experienced a hip fracture had a mortality rate of 16.9%. This
mortality rate was adjusted to take into account confounding health
factors and averaged for general bone density. Osteoporosis is one of
the primary culprits which lead to bone fractures, and Human Growth
Hormone has been shown to reduce the risk of these devastating breaks
through HGH Injections.
How is Osteoporosis Diagnosed?
Osteoporosis is officially designated by the World
Health Organization as a Mineral Bone Density which is greater than
2.5 Standard Deviations lower than the average bone density of young
and healthy individuals of normal bone health.
The Three
Forms of Osteoporosis
Primary Type 1 Osteoporosis:
Primary Type One Osteoporosis usually strikes in
women after menopause. This form of osteoporosis occurs in females at
a far greater rate than males. Women are diagnosed with Primary Type
1 Osteoporosis six times more often than males. This form of
Osteoporosis develops slowly after menopause (or Andropause in men)
and generally takes ten to fifteen years to become diagnosable.
Linked to Hypogonadism (Sexual Hormone
Deficiency)
This type of osteoporosis is directly linked to
sex hormone deficiency in both sexes. In women, Estrogen is vitally
important to the proper maintenance of bone health. In males, proper
Testosterone levels are equally as important. The reason why women
are diagnosed far more often than their male counterparts is that
Menopause represents a much more marked hormonal contrast than
andropause.
What is Andropause?
Andropause is the male form of menopause. During
the course of Andropause, Testosterone levels decline over time
leading to a highly symptomatic form of Testosterone Hormone
Deficiency. Testosterone levels start to decline around the age of
thirty, and this decline produces more and more problems as
Testosterone Levels in the body become increasingly meagre.
When does Andropause Lead to Osteoporosis?
Although men continue to produce Testosterone
throughout the lifespan, by the time men reach their fifties and
sixties, their bones start to become at risk for osteoporosis. A
number of other symptoms of Testosterone Deficiency can start to
appear much earlier, however. Muscle strength starts to deteriorate
in the late thirties and early forties. Metabolism rates can drop
significantly by the mid-thirties, leading to increased weight gain
exacerbated by a sedentary lifestyle.
Why does Osteoporosis Take so Long to become
Symptomatic?
The reason why bone health takes much longer to
decline is because of the natural resiliency of the skeletal system.
The bones have such a high rate of structural integrity that the
effects of hormonal deficiency take much longer to produce symptoms;
but, at the same time, the results of the deficiency are just as, if
not more, dangerous to the long term health of the male and female
body.
High-Turnover Osteoporosis
Primary Type One Osteoporosis is often referred to
as high-turnover osteoporosis because trabecular bone tissue degrades
at a rapid pace as the disease approaches a symptomatic point.
Trabecular bone tissue is also referred to as Spongy Bone or
Cancellous Bone. This type of bone tissue has a large amount of
surface area because of its naturally porous structure. Cancellous
bone degrades quickly as a result of osteoporosis because the already
porous bone becomes so structurally degraded that it becomes highly
prone to fractures and breakage.
This type of bone tissue is mostly located near
the edges of bones, near the cartilage in the areas which the bones
make contact with one another. Trabecular bone tissue is especially
densely allocated in the areas of the wrist and the spine, and for
this reason, patients who suffer from this form of osteoporosis are
much more at risk for carpal tunnel syndrome and spinal fractures.
Primary Type 2 Osteoporosis
Primary Type Two Osteoporosis is the form of the
disease that most men and women associate with Osteoporosis because
of its relationship with hip fractures. Type Two also affects women
at a higher rate than men. This form is only twice as common in
females as males, so it is more of a risk for men than Primary Type
One Osteoporosis. This manifestation of the disorder usually begins
to appear when adults enter their seventies and eighties.
Primary Type 2 Osteoporosis is often, but not
necessarily, related to Estrogen and Testosterone Production, but
rather Calcium Deficiency and Vitamin-D deficiency, which are the two
vitamins most highly associated with bone health and structural
integrity. There is also a significant amount of evidence that this
disorder is linked to higher activity in the Parathyroid gland
associated with the aging process.
What is Primary Type Two Osteoporosis?
This type of Osteoporosis occurs when the bones
have degraded to a point at which even the cortical bones begin to
break down. Cortical bones are the strong hard casings of the bone
which protect the functional interior bone and support the weight of
the body throughout day-to-day function. Primary Type Two
Osteoporosis is associated with a much higher likelihood for breaks
of the long arm and leg bones as well as the hips.
The Hips are Particularly Vulnerable to
Breakage
Hips are highly susceptible to this form of
osteoporosis because, although these bones are quite thick and
structurally strong, they are still thinner than many of the other
bones of the body. In addition to this, the hip bones take on an
extraordinary amount of stress because of their central, pivotal
location in the body. Another reason that the hip bones are highly at
risk for fracture and breakage is that seemingly innocuous falls
become incredibly hazardous as Osteoporosis worsens, and the hip bone
is most likely to take the majority of damage in this type of fall.
One slip and the hip bone could fracture or even shatter as a result,
depending on the force of the fall and the progression of the
disease.
Type One and Type Two Osteoporosis Are Unique
Disorders
Although Primary Type One and Primary Type Two
Osteoporosis are considered separate disorders, and Type Two can
sometimes occur even in the absence of Type One Osteoporosis, Type
Two Osteoporosis can also be the result of a progression of Type One.
Over time, the structure of the hips and spinal column degrades to a
point that these thicker bones begin to show symptoms as well.
It takes much longer for these bones to show signs
of wear because the cortical bones are much more compact. Dangerously
low levels of Bone Mineral Density take longer to result in fractures
and breaks. This is one reason why Type One Primary Osteoporosis is
most common between the ages of 55 and 70 and Type Two is more common
among patients 70 and olderType Two effects bones which are more
structurally sound.
Secondary Osteoporosis
Secondary Osteoporosis is the result of factors
outside of general nutrition, parathyroid activity, and sex-hormone
activity. In men and women who are healthy, the bone tissue is
constantly restructuring itself, replacing aging cells in order to
maintain optimal bone strength. To provide an example, this is why
after you break a bone when you are young, the bone is able to
rebuild and even become stronger than it was before. Have you ever
broken a bone? Run your hand along the area of bone that was broken
and you will likely feel that this area of bone is slightly thicker
than the bone tissue surrounding it. This is because the body reacted
to the damage by making the bone even stronger than it was before.
Bone Remodelling and Osteoporosis
The process of natural bone restructuring is known
as remodelling. The skeletal system is just like a road or a
building. Stress wears on the bones in the same way that it wears on
the tresses of a house or the concrete foundation of a street.
Eventually, the street needs to be repaved, and the support structure
of a building has to be inspected and maintained. In the body, the
bones go through the process of remodelling in order to keep the
bones constantly in a state of optimal strength.
Bone Formation and Bone Resorption
This natural process of remodelling is the result
of a delicate balance of two internal processes. The first process is
known as Bone Formation. In the process of Bone Formation, the bone
tissue pulls calcium from the blood stream in order to use it to
build and strengthen the bones. The cells which perform the task of
rebuilding the bones are known as osteoblasts. These cells use
enzymes and chemical reactions to pull the calcium from the blood,
mineralizing it and affixing it to the bones in order to strengthen
them.
The second process is known as Bone Resorption.
Bone Resorption is the process by which older bone cells are broken
down and turned back into parts which the osteoblasts can then use in
order to create healthy new bone cells. Osteoblasts and osteoclasts
function through the influence of hormones known as Paracrine
Signallers. Over the course of a year, ten percent of bone tissue
goes through the process of remodelling. When balanced, it is a slow
yet effective process for maintaining bone health.
Bone Turnover Rate and Osteoporosis Diagnosis
The mathematical formula regarding the maintenance
of Bone Remodelling is known as the Bone Turnover Rate. A healthy
Bone Turnover Rate would be a point at which bone tissue is replaced
efficiently, discarding or recycling old tissues and maintaining a
constant level of bone strength. Osteoporosis occurs when the Bone
Turnover Rate gets out of balance and the bone tissue is not recycled
and remodelled at the rate that the bone is either degraded by
osteoclasts or naturally breaks down as a result of the aging process
of the bone cell. Secondary Osteoporosis is the result of osteoclasts
that break down bone faster than osteoblasts can rebuild them,
causing the bones to break down and become porous as a result.
Causes of Secondary Osteoporosis
Secondary Osteoporosis can be the result of a
number of issues related to hormone imbalance, including:
Hyperparathyroidism The parathyroid
glands have a single purpose. They are responsible for regulating
calcium balance throughout the human body. Hyperparathyroidism is a
common cause of Secondary Osteoporosis. The Parathyroid Glands
release a hormone known as Parathyroid Hormone, abbreviated PTH, into
the blood stream. Hyperparathyroidism causes the body to constantly
send messages to the bones demanding that they release calcium into
the blood stream. This prevents the Osteoblasts from being able to
produce new bone at the rate that bone is being degraded, leading to
osteoporosis over time.
Hyperparathyroidism leads to a constant elevation
of calcium in the blood stream as well, because the body cannot
excrete the calcium released by the bones quickly enough. The kidneys
are also overworked, often leading to kidney stones. Kidney stones
are simply calcium deposits that form in the kidneys. If they grow
large enough they can block the path of excretion, causing great
pain. Hyperparathyroidism is usually the result of a parathyroid
tumor which causes the organ to release PTH in overdrive. This form
of Osteoporosis can strike men, women, and children of all ages, and
will not be cured until the tumor is removed or the disorder is
otherwise corrected.
Hyperthyroidism Overactive Thyroid
Glands prevent the body from storing phosphorus and calcium properly.
Hyperthyroidism causes bone turnover to occur at an escalated pace,
and the osteoblasts are no longer able to work fast enough to rebuild
bone. Hyperthyroidism also causes the body to pull calcium and
phosphorus out of the bones and diet where they are excreted through
the stool or through urination. The osteoclasts break down old bone,
and the excess materials are pulled into the blood stream.
This disorder becomes even more problematic when
combined with Estrogen Deficiency, Testosterone Deficiency, or Human
Growth Hormone Deficiency, because the two primary keys to bone
health are proper nutrition and proper hormone balance.
Hyperthyroidism often causes an issue known as hypercalcemia, where
the blood stream is flooded with excess calcium. Calcium levels in
these patients can be as much as 25% above normal.
Diabetes Insulin desensitization which
results in dangerous levels of blood sugar. Diabetes has been proven
to be correlated with reduced bone density, resulting in an increased
incidence of osteoporosis. Patients who suffer from Diabetes have
reported a history of bone fractures at a rate which is over 12 times
higher than their counterparts without diabetes. One reason that
Diabetes may affect osteoporosis is that high levels of blood sugar
in the body reduce the production of Human Growth Hormone by the
pituitary gland.
This reduction of HGH production leads to a
cascade of issues associated with HGH Deficiency, and Osteoporosis is
one of the most dangerous symptoms of Hypopituitarism. Human Growth
Hormone directly contributes to bone health, because Endogenous
Growth Hormone is converted into one of the primary Paracrine
Signallers known as Insulin-like Growth Factor One. IGF-1 plays a
direct role in the proper function of Osteoblasts, and when those
cells do not function optimally, the bone begins to degrade as a
result.
Cushings Syndrome Cushings
Syndrome is defined as symptoms which occur as a result of long-term
excess levels of cortisol in the body. Cushings Syndrome is a
symptomatic form of hypercortisolism. Hypercortisolism is simply
defined as excess levels of cortisol. Cushings Syndrome leads to
bone issues in a manner which is similar to Diabetes, although other
symptoms of the two diseases are incredibly different.
Long term hypercortisolism leads to a significant
decrease in the functional capacity of the osteoblasts. Cushings
Syndrome is common among football players and other professional
athletes because of the use of Cortisol as an anti-inflammatory and
pain relieving agent. Although Cortisol is the bodys natural
response to pain and inflammation, it also hinders the bodys
ability to produce Testosterone, Estrogen, and other hormones which
are related with long term health. Hypercortisolism also leads to
symptoms of Testosterone Deficiency such as mood disorders,
hypertension, diabetes, and muscle atrophy in addition to
osteoporosis.
Non-hormone Related causes of Secondary
Osteoporosis include:
Metastic Bone Disease - This is the stage
of cancer in which cancer cells spread throughout the body after
being released into the bloodstream. There are multiple reasons why
this causes osteoporosis dependent upon the regions of the body
affected.
Leukemia This causes White Blood Cells
to be generated at a highly escalated rate. This incredible increase
in white blood cell production interferes with the proper function of
osteoblasts, preventing them from restoring calcium and phosphorus
levels in the bones. White blood cells are produced by the bone
marrow in the same region in which osteoblasts primarily operate, and
the proliferation crowds out the osteoblasts.
Multiple Myeloma This is a stage of
bone cancers where multiple tumors grow throughout bone and bone
marrow tissue. Multiple Myeloma causes the bone marrow to produce
plasma at an uncontrollable rate which prevents the bones from
producing other important cellular organs which regulate Bone
Remodelling.
Thalassemia This is a hereditary form
of anemia in which the body does not produce enough red blood cells
for the body to function optimally. This causes symptoms of
osteoporosis and osteopenia to occur early in the life span, because
the Osteoblasts are not able to build bone as fast as it is broken
down. Thalassemia is also associated with Human Growth Hormone and
IGF-1 Deficiency.
Case
Study: Osteoporosis and HGH Deficiency
A study by Dr. Christian Wuster is related to the
effects of paracrine signals on the maintenance of the cycle of bone
remodelling.
Dr. Christian Wuster is a member of the Department
of Internal Medicine, Internal Endocrinology, and Metabolism at the
Heidelberg University Medical Clinic in Germany. In a recent study
released by he and his associates at the university, they provided
evidence that HGH Deficiency is associated with a reduction in bone
mass that causes an increased rate of osteoporosis, as well as
vertebral fracture.
Children who suffer from juvenile Growth Hormone
Deficiency struggle with inferior bone mineralization as a result of
their deficiency. Untreated, this prevents these juvenile patients
from experience the growth associated with puberty. Osteoporosis can
also occur as a result.
Bone Turnover Rates Briefly Decline Because of
HGH Treatments
When utilizing Human Growth Hormone Replacement
Therapy for patients with Growth Hormone Deficiency, the initial rate
at which bone turnover occurs is elevated for around the first six
months to year of treatment. This is because the system of bone
remodelling is in the process of returning to optimal function.
Before osteoblasts can do their jobs to full capacity, the
osteoclasts must play a role in feeding recyclable materials for the
process to occur at an optimal rate. After this point, the rate of
bone turnover reaches a balanced point, and the bones begin to
strengthen as a result.
From research involving individuals who have
acromegaly, there is evidence that dense bone mass increases as a
result of Human Growth Hormone Injections. The therapy has no effect
on the spongy bones in patients who do not suffer from
Hypopituitarism. In patients who suffer from hypopituitarism,
trabecular spongy bone mass decreases in area. Although there is a
decrease, the trabecular bones do have an increased mineral content
and their surface area increases.
In Cancellous Tissue, Greater Density Does Not
Always Mean Greater Strength
This means that although total bone mass decreases
slightly, the structural integrity of the bones actually increases
because the bone is healthier because the bone is more optimally
composed. One issue with osteoporosis in the trabecular bones is that
they are not remodelled efficiently. This means that bone tissue
begins to break down and weaken and lose its mineral content even
though overall mass remains stable or even increases slightly.
This data regarding trabecular mineral content was
previously shown to be true in laboratory animal studies involving
rats. In patients who suffered from Juvenile-Onset Growth Hormone
Disorder, HGH Replacement Therapy can be used in order to maintain
bone health, maturation, and Mineralization. Until a juvenile patient
achieves their final adult height they are injected with high doses
of Human Growth Hormone in order to simulate the natural process of
puberty which is caused by the endogenous production of high levels
of Human Growth Hormone by the pituitary gland.
Adult HGH Hormone Replacement Should Emulate
Normal Adult HGH Secretion
After the patient reaches Final Adult Height,
smaller doses of Human Growth Hormone should be used in order to
emulate HGH levels in the body during adulthood. Although Human
Growth Hormone is known primarily for its function in the growth
spurt of puberty, it is also vitally important to overall health
throughout the lifespan.
HGH Balance is Vitally Important to a Healthy
Life
Although Dr. Wusters study shows the importance
of Human Growth Hormone in order to prevent Osteoporosis, Human
Growth Hormone is also important in maintaining a number of other
vital functions as well. HGH encourages a healthy Body Mass Index by
facilitating the breakdown of adipose fat tissue. Human Growth
Hormone increases muscle mass by increasing the amount of energy and
nutrients available to the muscles during exercise. These are just
the three most obvious changes associated with Human Growth Hormone
Replacement Therapy.
Female Osteoporosis often Caused By Pituitary
Imbalance
In female patients who suffer from Osteoporosis,
Wuster finds that the Growth Hormone/Insulin-like Growth Factor 1
Axis is disturbed and incorrectly regulated, which results in a
reduction of bone strength. Post-Menopausal osteoporosis patients
have been shown to have low levels of IGF-1 and IGFBP-3 levels which
lead researchers to conclude that the osteoporosis is caused at least
in part because of a reduction in Growth Hormone Secretion or some
other issue involving the Hypothalamic-Pituitary Axis which prevents
IGF-1 and IGFBP-3 from being produced properly. IGFBP-3 is
Insulin-like Growth Factor-Binding Protein Three. The issues caused
by this exceed those caused by general hormone decline known as
Somatopause. Early-onset Somatopause could present issues in some
patients who suffer from arthritis, 24 hour Growth Hormone Profiles
do not change among patients who suffer from osteoarthritis and
osteoporosis.
What Weve Learned: Wuster, Osteoporosis, and
HGH
Wusters study provides evidence that there are
benefits to utilizing Human Growth Hormone shots as a treatment for
Osteoporosis. This is because Human Growth Hormone improves bone
mineral density and helps sustain a healthy balance of
osteoblast-osteoclast function leading to more efficient Bone
Remodelling. These benefits will produce their largest impact in
patients who are late post-menopause and suffering from Primary
Type-Two Osteoporosis, because the dangers of cortical bone and
spinal column fractures become very high during this period. Human
Growth Hormone Replacement Therapy may also be able to prevent
Osteoporosis and can greatly alleviate the symptoms of Primary
Type-One Osteoporosis.
Information regarding Dr. Wusters study was
acquired from the National Library of Medicine
Osteoporosis
and Hypogonadism
Bone
health is largely regulated by sex hormones in both males and
females. These Hormones play a role alongside Human Growth Hormone in
producing Final Adult Height in pediatric patients. In adults,
androgens play an important role in the maintenance of the skeletal
system as well. There is significant research that correlates
deficiencies in Estrogen, Testosterone, and other Sex Hormones with
Osteoporosis and other bone disorders.
Estrogen
hormones play a vital role in bone health. The male body has the
ability to convert Testosterone into Estrogen in order to maintain
bone health, although excess estrogen production is very unhealthy in
men. In men, the two organs responsible for Testosterone and Estrogen
production are the adrenal glands and the testes. In females, the
adrenal glands as well as the ovaries create Estrogen and
Testosterone. In males, Testosterone is produced primarily, and
Estrogen is produced more as a byproduct. In females, Estrogen is the
primary hormone produced.
The
Roles of Estrogen and Testosterone in Remodeling
The
sex hormones of both sexes have been linked to the production of
osteoblastic cells which work to maintain healthy bone structure. The
male and female sex hormones both play their own roles in maintaining
homeostasis. Progesterone and Estrogen slow down osteoclast cells,
reducing the rate at which bone turnover occurs. Testosterone
directly leads to the reproduction of Osteoblasts, increasing the
rate at which Bone Remodeling occurs. Estrogen Deficiency causes
Osteoporosis because it encourages the heightened activity of
osteoclasts.
Testosterone
Deficiency causes osteoporosis because it inhibits the function and
production of Osteoblasts. For this reason, Testosterone and Estrogen
Deficiency lead to Osteoporosis and Osteopenia. Estrogen Deficiency
is uncommon in males because the body converts Testosterone into
Estrogen. The primary problem which occurs in males is that high
levels of adipose fat or cortisol can upset the Sex Hormone Balance,
leading to Testosterone Deficiency at the expense of Estrogen and
Cortisol conversion.
Female
Obesity and Osteoporosis
In
females, obesity is not linked to Osteoporosis and higher body fat
levels are associated with stronger bones. Being underweight is
correlated with higher rates of Osteoporosis. A healthy weight for
women is keyenough body fat to reduce the risk of Osteoporosis,
but not so much that it inhibits longevity in other ways. In males,
on the other hand, obesity has been causally linked to Osteoporosis.
Healthy
Testosterone Levels Encourage Male Osteoblast Production
Male
muscle mass has also been shown to be linked to bone health as well.
Healthy Male Testosterone Levels are vital for bone health because
they encourage the activity of the osteoblasts. Although obesity
leads to greater Estrogen production which slows down osteoclast
metabolism, lower Testosterone levels greatly slow down the
reproduction and development of osteoblasts which still place Bone
Turnover Rates out of balance.
Human
Growth Hormone and Bone Mineral Density
Human
Growth Hormone is an essential ingredient to bone health in addition
to Testosterone, Estrogen, and Progesterone. Our knowledge of how the
sex hormones relate to Bone Mineral Density are much more evolved
than our knowledge of how Human Growth Hormone contributes to bone
health, but there is obviously a direct correlation.
Effects
of HGH Deficiency
Wusters
study is one of many which attempt to answer the question regarding
the mechanism by which Human Growth Hormone induces bone health. It
is clear that the anabolic processes of Human Growth Hormone and
IGF-1 cause the increase in height and bone mass during puberty. Its
also been shown that Healthy Human Growth Hormone levels maintain the
skeletal foundation during adulthood as well. Adult-Onset Human
Growth Hormone and IGF-1 Deficiency have also been clearly linked to
a number of negative health outcomes regarding the aging process as
well, including:
Reduced
Muscle Strength and Mass
IGF-1 creates an energy pipeline from Adipose Fat tissue to the
muscles, providing them with the energy that they need to function
optimally. Without proper sustenance, the muscles do not have the
nutrients they need to become larger and stronger and can atrophy as
a result.
Lower
Thresholds for Endurance
Lower levels of energy as a result of HGH Deficiency reduce the
amount of physical and mental energy at the disposal of an
individual, leading to problems with cognition, focus, and physical
endurance for exercise
Increase
in Adipose Fat
As a result of Human Growth Hormone Deficiency, fat around the
midsection begins to pool at an increased rate, because IGF-1 is one
of the primary metabolites which prevent fat accumulation.
Lower
Bone Mineral Density
IGF-1 and Human Growth Hormone encourage the production and
efficiency of osteoblasts, which increase the rate at which new bone
is generated and old bone tissue is replaced.
HGH,
IGF-1, and Bone Health
Human
Growth Hormone and its derivative IGF-1 both play a direct role in
overall bone health. HGH directly causes osteoblastic cells to be
formed in addition to Testosterone. Although HGH is required in order
to influence osteoblast creation, IGF-1 is necessary to encourage
many of the internal processes of the osteoblast cell. Rapid height
increases during the period of puberty are largely the result of
Human Growth Hormone, because excess HGH levels in the bones
encourage them to grow in length.
After
the epiphyseal plates harden in late adolescence, growth no longer
occurs and HGH production decreases to normal adult levels which
stimulate the production of IGF-1 while not inundating the bones with
excess HGH. Excess levels of HGH are associated with a number of
negative bone issues such as arthritis, carpal tunnel syndrome, and
acromegaly. Acromegaly is a bone disorder in which the bones of the
face, hands, and feet continue to grow past puberty as a result of
HGH stimulation, leading to physical contortions in bone structure.
IGF-1
also effects the production of osteoblasts, but at a much more modest
rate that is beneficial to those in adulthood. In addition to this,
the hormone increases the functional ability of osteoblasts after
creation. IGF-1 plays an integral part of normal bone density and
bone mineralization because IGF- increases the creation of collagen
while inhibiting its breakdown. IGF-1 affects the function of
osteoclasts, but so far, research has been unable to precisely figure
out how IGF-1 receptors on osteoclasts affect the function of those
cells.
Risk
Factors for Osteoporosis: Could I get Osteoporosis?
Although
Osteoporosis is a fairly common disorder, it certainly does not
affect all people and one can greatly reduce the risk of the disorder
through healthy living and being proactive. There are a number of
factors which can increase your chances of coming down with the
disease. Some of the factors which can lead to Osteoporosis are
hereditary, which means that they are a result of your personal and
individual genetic history. Other factors are the result of
particular lifestyle and nutrition choices or the result of
particular medicines.
Medical
and Biological Risk Factors for Osteoporosis
Sex
Females have much greater odds of being diagnosed with Osteoporosis
than males. Females are 6 times more likely to be diagnosed with
Primary Type One Osteoporosis and twice as likely to come down with
Type Two Osteoporosis. With Secondary Osteoporosis, the odds
fluctuate dependent upon the root cause of Osteoporosis. There are
four main reasons why women suffer from Osteoporosis more than men.
Women are on average thinner than males. Women have naturally lighter
bones than males. Menopause is correlated with a much sharper
reduction in Hormone levels than male Andropause, which is a slow and
steady decline that takes decades. The forth reason is that women
tend to live longer than males, and Osteoporosis is correlated
tightly with age.
Race
Asians and Caucasians are more likely to suffer from Osteoporosis
than other races. African American women have stronger bones on
average than their Caucasian counterparts. African American women
experience hip breaks and fractures at a rate of around half as often
as their Caucasian counterparts.
Age
Age is one of the most significant factors correlated with
osteoporosis. Bones begin to weaken slowly starting around the age of
thirty. It takes decades for the effects of Osteoporosis to begin to
show. In females, Primary Type One Osteoporosis tends to become
symptomatic when women are in the fifties and sixties. Primary Type
Two Osteoporosis usually occurs in the seventies or eighties. The age
at which Secondary Osteoporosis occurs can vary greatly dependent
upon the source of bone deficiency.
Heredity
Osteoporosis is highly correlated with genetic history. If older men
or women in your family suffered from spinal column or hip fractures,
then you may be at a greatly enhanced risk of the disorder. If you
have many relatives who suffer from back issues which result in
curvature of the spine and an inability to straighten the back, you
are also possibly at risk as well.
Body
Frame
Women who are thin or petite are at a greater risk of Osteoporosis.
Healthy body fat levels are related to elevated female Estrogen
levels which encourage the proper maintenance of bone mineral
density. Women who struggle with anorexia are highly at risk for
Osteoporosis, and long term anorexia can lead to Early-Onset
Osteoporosis.
Post-Menopausal
Women
Women who have already experienced menopause are at the highest risk
of Osteoporosis because of the sharp decrease in Estrogen and other
sex hormones. It takes ten to fifteen years for the symptoms to start
to appear, and many women choose to undergo Estrogen Replacement
Therapy in order to maintain the health of the bones. The bones are
incredibly resilient, so it takes years of hormone deficiency for the
bones to deteriorate as a result, but the deterioration is linked
with high rates of mortality.
Estrogen
Deficiency Females
who have suffered from Estrogen Deficiency their entire lives are at
a very high risk of Osteoporosis if they have not been properly
treated with Estrogen Hormone Replacement Therapy. Estrogen
Deficiency can be the result of early menopause, late puberty,
anorexia, or any method of suppressing the feminine cycle, as well as
the total absence of sexual development.
Medicine
Use
A number of medicines raise the incidence of Osteoporosis because
they have a negative effect on bone mineralization and mass over long
term usage. Anticoagulants, Immunosuppressants, anti-epileptic drugs,
and steroids have been shown to raise the risk of osteoporosis, as
well as thyroid suppression. Thyroid and Parathyroid Hormone are the
most direct contributors to bone health, and calcium cannot be
effectively used and recycled for Bone Remodeling if these hormones
are imbalanced.
Diet
and Nutrition Problems
Malnutrition, anorexia, chronic liver disease, and syndromes which
affect the absorption of Calcium and Phosphorus can greatly increase
the chances of osteoporosis.
Metabolic
and Endocrine Causes
Hemochromatosis, diabetes, and thalassemia all lead to increased
risk for osteoporosis. Thalassemia is a genetic disorder which leads
to anemia and hinders bone health greatly. Diabetes leads to erratic
and abnormally high levels of blood sugar which decrease the effect
and secretion of HGH and IGF-1. IGF-1 and Human Growth Hormone are
incredibly important in the maintenance of healthy bones and
Osteoporosis commonly results from diabetes. Hemochromatosis is a
disease which causes the body to absorb an abnormally high level of
iron. Although the effects of this disorder do not cause problems
immediately, after thirty to forty years, the symptoms appear and the
effects can be dramatic. Excess blood-iron levels are believed to
suppress osteoblast activity, leading to bone mineral breakdown and
Osteoporosis over time.
Other
Disorders Rheumatologic
disorders, renal tubular acidosis, certain cancers including myeloma,
mastocytosis, and Downs syndrome also increase the incidence of
Osteoporosis.
Lifestyle
Choices Increase Risk for Osteoporosis
Calcium
Deficiency Women
under the age of fifty should consume 1000 milligrams of calcium
daily. Women over seventy should have 1200 milligrams of calcium.
Calcium becomes a greater concern for males at the age of seventy and
older. Men under seventy should include 1000 milligrams of calcium in
their diet daily. Men over that age should take or consume 1200
milligrams each day. Calcium Deficiency is defined as daily intake of
300 mg, but recommended calcium intake is much higher.
Vitamin
D Deficiency Both
sexes should consume 400-800 IU of Vitamin D each day if they are
less than fifty years of age. Men and women over 50 should consume
800-1000 IU. This number can vary quite a bit, and some people need
more than others. It is recommended that the upper safe limit for
Vitamin D consumption is 4,000 daily IU. Caucasians and those with
lighter skin are more at risk for Vitamin D deficiency and need more
Vitamin D each day. Melatonin naturally converts sunlight into
Vitamin D, so African Americans and other dark skinned people need
less supplemental Vitamin D. Vitamin D is a key component of Calcium
intake which helps absorb calcium from its dietary form to a usable
form. Vitamin D can be found in a number of foods, including certain
fish, fortified cereals and milks, and egg yolks.
Excess
Caffeine Ingestion Although
it does not appear that drinking caffeine has a negative effect on
calcium levels in healthy patients, those who do not consume enough
calcium in their diet will find that their Calcium Deficiency is made
worse by having too much caffeine.
Sedentary
Lifestyle Healthy
levels of Human Growth Hormone and IGF-1 are important for
maintaining healthy bones. A sedentary lifestyle is one of the worst
culprits in inducing or exacerbating Human Growth Hormone Deficiency.
HGH is released at its highest rates during two periodsduring deep
sleep and during exercise. Living a life without exercise and
physical exertion can lead to Hypopituitarism which inhibits the
development and propagation of healthy and optimally functioning
osteoblasts. In addition to this, the bones need exercise as much as
any other organ, and physical exercise also creates pressure on the
bones which encourage the body to maintain their structural
integrity.
Use
of Nicotine and Tobacco Smokers
lose bone density at a rate higher than nonsmokers. An analysis of
twenty nine studies shows that the risk of hip fracture increases by
17% at age sixty, 71% at age eighty, and a whopping 108% at age
ninety. Although these effects are cumulative over time, making the
decision to quit smoking at any age will reduce future risk of
fractures associated with Osteoporosis and tobacco use.
Alcohol
Heavy
use of alcohol can have a negative effect on calcium absorption.
Alcohol when used in excess can cause the pancreas to take in
nutritional Vitamin D and calcium at a reduced rate. It also
overloads the liver, which can reduce the efficiency of Vitamin D
activation. Heavy alcohol use has been shown to destroy osteoblasts
as well. Excess alcohol can also disturb Estrogen secretion in
females. Chronic alcoholism causes an increase in parathyroid hormone
production as well as cortisol production. Both of these hormones
have a negative effect on the Bone Remodeling cycle, leaching Calcium
from the bones and out through bodily excretions.
How
Can I Stop Osteoporosis?
Even
if you are not at a genetically high risk of Osteoporosis, there are
a number of ways that you can strengthen your bones and reduce the
threat of Osteoporosis.
Increase
Calcium
Consumption
The
simplest way to reduce the risk of Osteoporosis is to take in a
healthy amount of calcium each day. Choose foods which are ripe with
calcium or take a daily calcium supplement in addition to the calcium
that you naturally take in through diet. It is important to maintain
healthy calcium consumption throughout your life because of the long
term consequences of calcium deficiency. Poor nutrition habits you
have now may come back to bite you decades later if you do not keep a
preventative mindset. The bones begin to lose mass after the age of
thirty, so it is important to maintain adequate calcium levels
throughout childhood and early adulthood so that your bones can be as
strong as possible when decline inevitably begins. After the age of
thirty, calcium intake will help minimize bone loss while
strengthening bones through proper mineralization, reducing the risk
of fractures later in adulthood.
If
you are utilizing calcium pills, make sure that they also have
Vitamin D, because of the positive effect that Vitamin D has on
calcium absorption. Also pay attention to the type of calcium
supplement that you buy. Calcium carbonate is inferior to calcium
citrate because it is not absorbed by the body as easily. One other
advantage to calcium citrate is that it does not have to be taken
with food. If you use calcium carbonate, make sure you take the
supplement with food in order to ensure sufficient absorption.
Vitamin
D
Maximize
Vitamin D consumption either through Supplementation or changes in
diet. Although less may provide you the benefits that you need,
consuming 1200-2000 IU daily will ensure that you are getting the
level of Vitamin D you need at any age without putting you at any
risk for taking too much. Again, good foods to eat for Vitamin D are
Fortified foods, egg yolks, shrimp and many fish including pink
salmon, sardines, mackerel, and halibut. Cod liver oil makes a great
supplemental form of Vitamin D as well.
Exercise
There
are three important forms of exercise when it comes to preventing or
slowing down Osteoporosis. The first form of exercise is
weight-bearing exercise. This form of exercise is simply staying on
your feet and getting out and about. You can go hiking. You can
dance. Literally anything that keeps you moving and on your feet for
an extended period of time qualifies. One important note biking
and swimming are not effective forms of weight-bearing exercise.
Although they tax the cardiovascular system, they do not put the form
of load-bearing stress on the body which maximally benefits those at
risk of Osteoporosis. Thirty minutes to an hour of physical exertion
weekly is optimal to provide the best health benefits.
Resistance
training is also very important when preventing or slowing
Osteoporosis as well. Resistance training is simply described as
weight lifting. This form of exercise makes the muscles larger and
stronger, and helps the bones become more structurally sound. You can
lift weights or utilize spring or tube systems to provide resistance
without lifting weights. Exercising in water is also a very effective
means of resistance training, especially for older men and women who
are at high risk of osteoporosis and bone fractures. For optimal
results, one should work out in this manner at least three times each
week. It is also incredibly important to alternate muscles, both to
reduce wear and tear, and because the muscles repair and rebuild
themselves primarily during rest periods.
Resistance
training is effective largely because it encourages your body to
secrete more Human Growth Hormone. HGH helps make your bones more
resilient and strengthens the muscles as well. For patients who are
taking Human Growth Hormone Replacement Therapy or IGF-1 Injections,
Weight training increases the effectiveness of these hormone shots.
Stretching
Stretching
and flexibility exercises are incredibly beneficial for those that
are at risk for Osteoporosis. Flex exercises increase the ability of
the joints to withstand stress which can greatly reduce the threat of
falls or other types of injuries. Limber joints allow you to avoid
bad falls and prevent minor and major bone fractures. If you are
looking for a simple way to increase flexibility, going through
routine stretches every day is a simple and incredibly safe way to
get limber.
If
you really enjoy flexibility exercises and would like to combine
stretching with cardiovascular exercise, yoga is a fantastic way to
keep in shape. If you have already had issues with Osteoporosis in
the past, make sure that you engage in stretching exercises or other
forms of exercise which do not overtask the hips and spinal column to
reduce the risk of further issues.
The
important thing is to make sure whatever you do is safe for your
body. Talk to your doctor before you alter your routine of physical
activity, especially if you are older and at high risk for
complications resulting from Osteoporosis. Its vitally important
that you engage in a form of exercise that your body can handle while
also ensuring that you are putting stress on your muscle, bones, and
joints.
What
Medicines Treat Osteoporosis?
As
of today, there are a handful of medicines which have been shown to
be very effective in preventing or treating Osteoporosis
Estrogen
Hormone Replacement Therapy (HRT)
Estrogen
HRT has been proven to be highly effective in both staving off and
alleviating the effects of Osteoporosis in women. Estrogen Treatments
have been shown to greatly decrease bone loss while also boosting
bone density in the hips and spine, the two areas most susceptible to
Osteoporosis. The spinal column and hips are also the two areas in
which Osteoporosis creates the most devastating injuries. For female
patients, the risk of bone fracture in these two vital areas is
reduced significantly through the usage of Estrogen Replacement
Therapy.
Estrogen
Patches, Pills, and Injections
Generally,
Estrogen HRT is provided via patch and pill, although Estrogen
injections are often used as well. Estrogen Injections are primarily
used to alleviate the effects of menopause, and Estrogen Patches and
pills are more often used in order to treat symptoms of low Estrogen
levels such as Osteopenia, Osteoporosis, and low libido. Estrogen
Hormone Treatments are effective when began at any age, but they are
most effective when used as a preventative measure in order to
attempt to bypass Osteoporosis altogether.
Estrogen
Replacement Therapy is Paired with the Hormone Progestin
One
of the main risks associated with taking Estrogen Replacement Therapy
alone is that can raise the risk of experiencing endometrial cancer,
which is a cancer of the uterine lining. In the menstrual process,
spikes in estrogen levels cause the line of the uterus to thicken in
a monthly cycle. Excess use of Estrogen can lead to undesired growth
of endometrial tissue which can in some cases develop into cancer.
New therapies have been created which greatly reduce the risk of
endometrial cancer when utilizing Estrogen Hormone Replacement
Therapy. Today in most cases where Estrogen HRT is utilized, a
hormone known as progestin is provided alongside estrogen in patients
who still have a uterus. Progestin prevents endometrial hyperplasia,
which is the rapid build-up of endometrial cells which develop as a
result of unopposed Estrogen Replacement Therapy.
Why
are Estrogen and Progestin used together?
Normally
in a hormonally stable woman, Estrogen and Progestin work as
counterbalances to one another in order to maintain the normal cycle
of endometrial development. After menopause, the release of both of
these hormones drops precipitously. Because introducing exogenous
Estrogen does not cause an increase in progestin, progestin must be
supplementally supplied as well.
Side
Effects of Estrogen HRT
Side
effects of Estrogen Hormone Replacement Therapy include hypertension,
breast sensitivity, bloating, and nausea. Evidence suggests that
while high blood pressure can be an issue in female patients
utilizing birth control products which include Estrogen. Estrogen
Replacement Therapy provides a much lower level of Estrogen which is
not believed to lead to hypertension. Water Retention is a direct
result of estrogen use and in most patients will not be an issue, or
will not be severe enough to suspend or alter therapy. If you
experience bloating as a result of Estrogen Replacement Therapy, you
can talk to your doctor about dietary changes to resolve bloating
issues, and there are also medications you can take which will help
to resolve the issue as well. Some patients respond to oral estrogen
negatively and experience nausea as a result. For these patients,
switching to a patch should resolve the issue entirely. Breast
tenderness can be resolved either by changing to a patch or by
adjusting the dosage.
Estrogen
and Breast Cancer Risk
The
current body of scientific evidence does show that long term Estrogen
Replacement Therapy is correlated with an increased risk of breast
cancer, so if you are at an increased risk of breast cancer or
currently have breast cancer, you should avoid Estrogen HRT unless
you have been given the okay by your physician. Although Estrogen
Replacement Treatments are effective at alleviating Osteoporosis, it
is not commonly prescribed for periods longer than a few years,
because of the increased risk of breast cancer that occurs with
prolonged usage.
Testosterone
Hormone Replacement Therapy
Testosterone
HRT is often effective in male patients who suffer from Osteoporosis.
Male Osteoporosis often goes unidentified and misdiagnosed because of
its relative rarity, but male hypogonadism can lead to a hormone
imbalance which can negatively impact the bone mineral density of the
skeletal system.
Male
Osteoporosis Less Common
Although
Male Osteoporosis is much less common, it is still a major issue that
occurs with enough frequency that male bone health should be
cautiously monitored with age. Testosterone plays a vital role in the
maintenance and proliferation of the osteoblasts, and in patients who
suffer from Low Testosterone and especially those who have total
hypogonadism need Testosterone Treatments in order to strengthen the
bones as well as maintain physical strength, cognitive ability, and
sexual libido.
Increase
in Male Osteoporosis in Recent Years
There
has been an uptick in diagnoses of Male Osteoporosis in the last
generation, and there are a number of factors which may contribute to
this. Men are living longer than they once were, and they are more
prone to experiencing Primary Type Two Osteoporosis, which tends to
effect males in their seventies and eighties rather than earlier in
life like Primary Type One Osteoporosis, which affects females
significantly more than males.
Osteoporosis
and the Sedentary Workplace
Also,
because males are more often working in sedentary environments,
Testosterone Deficiency is more of an issue than it has ever been
before. In Great Britain, for example, it is believed that
Osteoporosis affects one in every twelve men and one in every six
males over the age of eighty will experience a fractured hip at some
point in the rest of their life. Men who suffer from hypogonadism
have been shown in scientific research to experience rates of bone
turnover that are far higher than healthy men.
Male
patients who have experienced minor hip or spinal fractures are
encouraged to seek Testosterone Replacement Therapy. In addition to
this, Hypo-gonadal patients who have been proven to have reduced Bone
Mineral Density will also likely benefit greatly from Testosterone
injections.
Testosterone
Replacement is a Natural Therapy
Many
physicians are now recommending Bio-Identical Testosterone HRT as an
alternative to Bisphosphonates because Testosterone HRT is a much
more natural form of therapy which mimics and enhances the bodys
natural processes. With all of the other positive benefits provided
by Testosterone Replacement Therapy for Osteoporosis, it seems to be
a clear choice for male patients as Osteoporosis and Low-T begin to
manifest themselves with age.
Testosterone
Replacement Therapy for Low-T and Osteoporosis produces minor or no
side effects in the great majority of patients. The most reported
side-effects of BioIdentical Testosterone Hormone Replacement are
skin abrasion and rashes at the administration site, slightly
increased hemoglobin count, decreased HDL (Healthy Cholesterol), and
acne.
Testosterone
Replacement Therapy Produces Few Significant Side-Effects
A
cross-section of ten studies showed no major adverse reaction to
therapy in any of the trials. Testosterone should not be used by
patients who are suffering from prostate cancer, because Testosterone
Hormone Replacement Injections can exacerbate existing prostate
tumors. Also, patients who utilize anti-coagulants should be
especially cautious with Testosterone Replacement because of the
effect that Testosterone Replacement sometimes has on hemoglobin
counts.
Human
Growth Hormone Replacement Therapy
Growth
Hormone Injections are a new method for Osteoporosis treatment in
comparison to the others listed, but it still shows promising
results. The Wuster Study cited earlier in this article is evidence
in favor of Human Growth Hormone HRT, and there are many other
studies which present similar evidence. HGH Hormone Replacement
Therapy works by encouraging the proper function of Osteoblasts
through the intervention of exogenous IGF-1.
HGH
Makes Osteoporosis Prevention Easier
In
addition to this, HGH Hormone Treatments also encourage physiological
changes which lead to enhanced outcomes. Human Growth Hormone
alleviates adipose fat accumulation, which discourages excess
estrogen production in males and also increases the effectiveness of
endogenous HGH secretions.
HGH
Injections also have a tendency to reduce fatigue and bolster muscle
mass and strength, which helps patients maintain an exercise program
which can help them strengthen their bones and muscles in a way that
enhances outcomes and reduces the risk of fractures in the future in
patients who suffer from either osteopenia or osteoporosis.
HGH
Treatments Have Low Incidence of Major Side-Effects
In
studies regarding HGH Hormone Replacement Therapy for the Treatment
of Male Osteoporosis, only minor side-effects were reported, and the
vast majority of patients did not suspend treatment as a result of
the therapy.
For
female patients, there is a high likelihood that HGH Hormone
Replacement Therapy will cause Estrogen Replacement for Osteoporosis
to fall out of favor. For men, on the other hand, it appears that a
combination of HGH and Testosterone HRT may produce the best outcomes
in regard to both Osteoporosis and overall life quality.
Bisphosphonates
Bisphosphonates
are medications that have the ability to slow down the rate at which
bones are broken down by osteoclasts, inhibiting the resorption of
bone tissue. By slowing down the effect of resorption,
Bisphosphonates are able to stabilize the process of Bone Remodeling
in order to increase the structural strength of the bones, decreasing
the dangers of Osteoporosis. These medicines have been proven to
boost bone mineral density while also lowering the incidence of
fractures of the spinal cord and the hip.
For
post-menopausal females, the Food and Drug Administration-approved
Bisphosphonate medication is known as Alendronate. Bisphosphonates
produce a few side effects, the most constant being gastrointestinal
discomfort and acid reflux. These issues can be resolved by making
sure to take the medication without food and with an entire glass of
water. Also, remain sitting or standing for a half hour after taking
the medication in order to prevent stomach discomfort.
Atrial
Fibrillation and Bisphosphonates
Another
more dangerous side effect which is believed to result from the usage
of Bisphosphonates is atrial fibrillation. It is believed that around
one in every thirty cases of atrial fibrillation is the result of the
use of Bisphosphonates. Female patients who are particularly at risk
for cardiovascular disease, heart attacks, or diabetes should only
use this drug at the recommendation of their physician while
considering cost-benefit analysis.
Bisphosphonates
and Femur Fractures
In
very rare cases, femoral fractures can result from Bisphosphonate
Therapy, but this occurs in fewer than 1 per 1000 cases, and the
benefits exceedingly outweigh the risk of this issue. The reason why
it is believed that this occurs is that long term suppression of Bone
Remodeling prevents the femur from recovering from minor structural
issues. This drug has the ability to break down osteoclasts, and as a
result, the bone is not broken down for recycling by osteoclasts and
bone structural integrity very slowly declines. Over time in this
minority of cases, this leads microfractures to combine into large
and more fragile areas prone to more significant fracture.
Calcitonin
This
form of therapy is a potential course of advantage for females who
are not able to utilize Estrogen HRT or other forms of Hormone
Replacement. Calcitonin can be prescribed for female patients that
passed through menopause a minimum of five years prior to
prescription. For these women, Calcitonin can be used to raise the
density of the spinal column while reducing bone mass atrophy.
Calcitonin (also known as thyrocalcitonin) is a thyroid hormone which
promotes stronger bones by helping maintain healthy metabolism of
phosphorus and calcium.
Because
Calcitonin is a complex hormonal protein, it cannot be taken orally.
The hormone would be broken down by the liver before it had the
opportunity to function, because of its structure. Calcitonin can be
delivered either as a nasal spray which is absorbed into the sinus
membrane or as a Calcitonin Shot. Calcitonin inhibits the function of
Osteoclasts, reducing the rate at which Bone Resorption takes place
while also having a beneficial effect on cartilage formation.
Selective
Estrogen-Receptor Modulators
These
medicines and molecules have the ability emulate the function of
Estrogen on certain Estrogen Receptors. Different forms of SERM
medications have the ability to mimic different aspects of Hormonal
Estrogen dependent upon their structure. Three common forms of SERM
used for treatment of Osteoporosis are Femarelle, Lasofoxifene, and
Raloxifene. These drugs can also be used to resolve other issues,
included but not limited to Menopause Management, Breast Cancer, and
Contraception.
Raloxifene
Best SERM for Osteoporosis
Raloxifene
has been shown to be particularly effective at resolving Osteopenia
and Osteoporosis issues in the spinal column and the hips. For this
reason, the drug has been FDA-approved as the most effective SERM in
regard to bone health and Osteoporosis prevention. Although the drug
does benefit the skeletal system, current evidence shows that
Raloxifene is less effective at alleviating and preventing spinal
osteoporosis than either Calcitonin, Estrogen Replacement Therapy
(for women), and Testosterone Replacement Therapy (for men).
One
of the most significant benefits of this drug is that side-effects
are incredibly rare, so the drug can be incredibly beneficial for
patients who are not able to utilize Hormone Replacement Therapy or
Calcitonin treatment. A very small minority of female patients have
reported hot flashes similar to those experienced during menopause.
An even smaller subset reported Deep Vein Thrombosis, which is a
potentially dangerous blood clot in the leg.
Conclusion:
Osteoporosis and Hormone Replacement Therapy
There
are a number of remedies that can be used in order to prevent or
alleviate the symptoms of Osteoporosis. Although many different
options provide their own benefits and potential drawbacks, Hormone
Replacement Therapy is often the most effective form of treatment.
Benefits
of Estrogen Replacement Therapy
Estrogen
Replacement Therapy can be very beneficial for short to
intermediate-term treatment of Female Osteoporosis. In addition to
this, Estrogen HRT has also been shown to provide these other
benefits as well:
Alleviating
the effects of Menopause, reducing the severity of hot sweats and
cold flashes
Improves
mood stability after menopause
Decreases
incidence of insomnia and sleeping disorders in post-menopausal
patients
Produces
healthier skin by increasing collagen levels in the outer layers,
smoothing wrinkles and tightening the muscles of the face
Alleviates
the symptoms of Peri-menopause and Early-Onset Menopause
Increases
libido and alleviates vaginal dryness during menopause
Because
long term use of Estrogen can increase the risk of breast cancer,
long term use of Estrogen Replacement Therapy is not usually
recommended, but Estrogen Replacement Therapy utilized in the years
of menopause can delay the symptoms of Osteoporosis by preserving
bone health. The risks in utilizing Estrogen HRT are very low when
used for a relatively short period of time, but utilizing the
treatment for ten or more years may lead to unacceptable breast
cancer risk. In the future, these recommendations may change
significantly, because newer research suggests that Estrogen
Replacement Therapy can be effective at maintaining bone health even
at very low doses which do not significantly increase the risk of
breast cancer.
Benefits
of Testosterone Replacement Therapy
Testosterone
HRT is one of the most talked about Hormone Treatments available in
the United States today. Although the body of research is not as
large as that for Estrogen Hormone Replacement, there is significant
evidence that Testosterone HRT can be highly beneficial for male
patients at risk or experiencing Osteoporosis or Low Bone Density.
Hormone Replacement Therapy with Testosterone produces a number of
other benefits which can make Osteoporosis prevention seem like an
added bonus. The following are common benefits of Testosterone
Replacement Treatments:
Increases
in libido
Resolves
sexual dysfunction and alleviates premature ejaculation
Boosts
and/or preserves muscle mass
Enhances
cognition and memory faculties
Prevents
depression and stabilizes mood while suppressing anxiety
Alleviates
pain in the joints and muscles
Increases
energy and reduces feelings of exhaustion
Raises
ones overall sense of well-being
There
are some side-effects associated with Testosterone Injections,
patches, and creams, but for patients who utilize low-dose
Testosterone treatments for Testosterone Deficiency, major
side-effects are incredibly rare, and the vast majority of patients
either experience no side effects or minor side effects. It is
estimated that Testosterone Replacement Therapy for Low-T can
actively benefit half of men in their fifties. For men in their
sixties, the number is estimated to be even highersixty percent!
As the body of knowledge surrounding Testosterone as an Anti-Aging
Therapy grows, it is inevitably that new and perhaps greater benefits
will also be revealed as well.
Benefits
of Human Growth Hormone Replacement Therapy
HGH
Hormone Replacement Therapy has only been studied as a potential
treatment for Osteoporosis in recent years, but the benefits seem to
show high levels of potential. HGH proves time and time again that it
is a vital hormone which greatly alleviates the negative aspects of
the aging process while preserving optimal function and metabolism in
multiple systems of the body. We may eventually find that HGH plays
at least some role in every single important process of the body. Dr.
Wusters recent Human Growth Hormone for Osteoporosis study shows
that HGH has the ability to increase bone density as a result of the
positive interaction that takes place between HGH, IGF-1, and the
osteoblast. This form of therapy seems equally beneficial for both
men and women. This treatment is also likely safer and provides
similar benefits to Estrogen Replacement Therapy for Osteoporosis
without producing the side-effect of increased cancer risk.
HGH
Shots also provide a number of other significant benefits in addition
to the prevention of Osteoporosis, including, but not limited to:
Increased
metabolism
Breakdown
of unhealthy adipose fat tissue
Increase
in muscle mass and strength
Improved
sleeping habits
Boosted
nutrient absorption
Enhanced
Energy
Reduced
Fatigue
Increase
overall sense of well-being
Although
there is a certain risk for side-effects when using Human Growth
Hormone, these risks are generally associated with individuals who
abuse the drug for the purpose of performance enhancement. HGH is not
legal for use as a PED in the United States, and can only be used by
those who have a diagnosable Human Growth Hormone Deficiency or other
legitimate medical condition such as Hypopituitarism or Childhood
Idiopathic Short Stature.
The
Conscious Evolution Institute
The
Conscious Evolution Institute is one of the nations leading
Anti-Aging and Regenerative clinics. Osteoporosis is one of the most
devastating conditions related to the aging process. Sadly, if more
men and women were proactive, the disorder would be much less
prominent than it is today. There are many ways to treat the disease,
and for many individuals, Hormone Replacement Therapy with
Testosterone, Estrogen, or HGH may be the right answer.
We
urge you to give us a call today if you are feeling the effects of
Hormone Deficiency. There is no pressure to commit, and we have a
friendly, knowledgeable, and experienced staff that will be happy to
take the time to answer any questions you may have about our
treatment options. At the Conscious Evolution Institute, we work with
you to create a life plan that will help you maximize the benefits of
Hormone Replacement. Its not just a medical treatment, its a
lifestyle revolution. In addition to your Hormone Medications, we
will also work with you to design a work out and nutrition plan that
will help you get into shape. We have helped thousands of men and
women all across the United States alleviate and reverse the effects
of aging and we want to help you as well.
National
Network of Conscious Evolution Institute Affiliates
If
you are interested in the treatments we provide, please fill out the
form on our website or call our toll-free number today. We have a
certified network of affiliated physicians all across the United
States, so there is no need to visit us in person. Our affiliates
gather all the necessary data we need in order to provide an accurate
diagnosis, including Family History, Blood Sample, and Routine
Physical. After we receive your diagnostic data, we will have
everything we need to make an accurate diagnosis. You will receive
your diagnosis in around five business daysNo need to wait! After
we fill out your prescription, we can ship the product via FedEx
straight to your door. Its just that easy. Again, we encourage you
to call us today at the Conscious Evolution Clinic. Dont put it
off any longer. If you are over the age of thirty and feeling the
adverse effects of the aging process, we can help! We look forward to
hearing from you.
Yours
in Longevity,
The
Conscious Evolution Institute
|
We
recommend
