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Written by Dr. Welsh, Article reviewed and edited by Dr. Fine M.D..
Published on 06 May 2021

Belly fat is stubborn and frustrating. Resculpting the body to get rid of body fat is not a simple and easy task, though it is certainly not impossible. One of the reasons why it is so hard to burn belly fat is that your body primarily uses the midsection as its storage unit for fat. Hormone Balance helps us avoid the buildup of belly fat. It's also true that, as we get older, we become more prone to hormone imbalance as levels of HGH and Testosterone fall into decline. In women, the changes associated with Menopause also contribute heavily to increased body fat. What it comes down to is that the older that you get, the harder that it becomes to stay lean. Body fat can become especially stubborn when folks reach their forties and fifties. This is the period when the decline of important hormones often becomes noticeable and problematic.

Sources of Hormone Imbalance Associated with Belly Fat

Hormone Imbalance is often multifaceted, and the accumulation of body fat is often the result of multiple sources of imbalance. The following are several hormones and how they are associated with belly fat: Testosterone – Testosterone is intimately associated with masculinity and male optimal function. Testosterone helps maintain muscle mass. The more lean muscle that you have, the higher your basal metabolism, which protects against body fat. Testosterone Levels decline when men get older, which reduces metabolism and muscle mass and makes it easier for belly fat to stick around.

Estrogen – Estrogen is most important for women but also plays a critical role in men's health (in small doses). Men produce Estrogen from body fat. The more fat accumulates, the more Estrogen that they will make. Unfortunately, Estrogen is also a limiting factor on Testosterone Production. This is one of several feedback loops associated with obesity. Belly Fat increases Estrogen, which Suppresses Testosterone. Lower Testosterone makes it easier to gain weight which further increases the influence of Estrogen.

Insulin – Insulin is the tool that the body uses to capture free glucose from the bloodstream and transport it to fat cells for storage. Insulin resistance leads to weight gain because the increased concentrations of Insulin in the bloodstream make it harder to free energy stored as body fat.

DHEA – DHEA is a precursor hormone produced by the Adrenal Glands, which is integral to the production of Estrogen and Testosterone. Healthy DHEA activity helps ward off belly fat by promoting healthy Sex Hormone Production and improving the body's responsiveness to Insulin.

Cortisol - Cortisol is the body's key stress hormone, associated with both physical and psychological stress. Cortisol initiates fight-or-flight response and stimulates activity. Cortisol is critical to health but also very prone to imbalance. Chronic Stress causes Cortisol Levels to skyrocket, depleting the building blocks that would normally be available to produce Testosterone and other hormones that are important to stave off body fat. Cortisol both increases appetite and increases Insulin, meaning that you eat more calories, and your body is more prone to storing them as fat.

Ghrelin – Ghrelin is the hormone most directly associated with the sensation of hunger. Ghrelin is responsible for increasing appetite, and high levels of Ghrelin also encourage you to both eat more and store more calories as fat. Crash diets significantly increase Ghrelin production, which contributes to the long-term failure of extreme diets. Ghrelin increases the production of HGH, which helps break energy free from body fat. Intermittent Fasting and other diets which allow for moderate Ghrelin activity are good for weight loss, but extreme diets are counterproductive.

Adiponectin – Adinopectin stimulates weight loss and the breakdown of body fat. Obesity reduces Adinopectin activity. Adiponectin Levels are adversely affected by high levels of Insulin, blood sugar, and body fat. The body's fat-burning power is directly correlated with healthy glucose/Insulin dynamics.


Written by Dr. Welsh, Article reviewed and edited by Dr. Fine M.D..
Published on 30 April 2021
Hormone Therapy is a highly effective means to treat various forms of cancer, especially Prostate Cancer and Breast Cancer. In spite of their effectiveness, however, these treatments come with their own long-term risks. The American Heart Association recently provided a statement regarding these risks in Circulation: Genomic and Precision Medicine. For example, HRT Regimens designed to treat Prostate/Breast Cancer also increase the chance of dangerous cardiovascular dangers such as stroke and heart attack. According to the American Heart Association, these risks can be greatly mitigated with sufficient awareness and preliminary evaluation. This report offers updated information regarding the complications associated with various forms of Hormone Therapy. The report is designed to help medical specialists treat cancer effectively while managing the downstream risks associated with Hormone Replacement Therapy.

Breast and Prostate Cancer Treatments Improving

Breast Cancer is the most common kind of cancer in the United States, accounting for 30.3% of cancers in women. Among males, prostate cancer is the most common, at 21.5% of all male cancer diagnoses. Aside from skin cancer, most common cancers are associated in some way with hormones. As cancer therapies become more advanced, fewer patients succumb to the cancer itself. In fact, among those patients under HRT Treatment for hormone-dependent cancer, cardiovascular disease is the leading mortality risk.

Common Treatments for Breast and Prostate Cancer

Three of the most common Endocrine Treatments for cancer are Selective Estrogen Receptor Modulators, Aromatase Inhibitors, and Androgen Deprivation Therapy: SERMs are designed to eliminate tumor development by preventing cancer cells from feeding off of Estrogen. These treatments allow Estrogen to act normally in other parts of the body like liver/bone tissue without acting on breast tissue. Two common SERMs are ralloxifene and tamoxifen. Aromatase Inhibitors suppress the production of Estrogen and are commonly prescribed to women after menopause, especially high-risk patients. Letrozole, anastrozole, and exemestane are prominent examples of Aromatase Inhibitors. Androgen Deprivation Therapy refers to treatments designed to treat prostate cancer by cutting off access to the fuel source of Testosterone. This category is more broad. Some prescriptions block Testosterone from Prostate Cancer Cells (and prostate cells themselves). Another option includes medications that suppress the hypothalamic/pituitary activity which triggers Testosterone production.

Cardiovascular Complications Associated with Cancer Treatment

Unfortunately, all of the treatments above can have negative consequences for the cardiovascular system. For example, Aromatase Inhibitors are known to increase heart attack and stroke risk, and Tamoxifen can lead to blood clots. Because cancers can become resistant to certain treatments, sometimes patients have to change therapies for best results against the cancer. Unfortunately, while this improves cancer outcomes, it also further increases the odds of cardiovascular problems, including blood clots, arrhythmia, and high blood pressure. In men, Androgen Deprivation Therapy causes them to experience the full gamut of issues associated with Low-T, including impaired glucose metabolism, increased body fat, and heightened triglyceride/cholesterol levels. For all of the above treatments, the longer a patient is on the regimen, the greater the risks associated with the therapy. Researchers are investigating exactly how duration impacts risks. HRT Therapy for Cancer was riskiest for patients diagnosed with heart disease and those with multiple risk factors (including history of stroke/heart disease, smoking, high cholesterol, obesity, and high blood pressure). The American Heart Association published this report to help doctors and patients understand the risks associated with Prostate/Breast Cancer Treatment and the cardiovascular precautions that should be taken to maximize outcomes for patients. In the near future, there will hopefully be official guidelines to help doctors navigate the heart risks associated with HRT-Based Cancer treatment. Any patient that could benefit from Hormone Therapy for Cancer should first be directed to a cardiologist for testing and consultation.


Written by Dr. Welsh, Article reviewed and edited by Dr. Fine M.D..
Published on 27 April 2021

Turmeric is a yellow spice commonly found in Indian and other Asian cuisines but Americans and Europeans have been using this spice more and more after hearing about its amazing benefits for health. No wonder turmeric has been used for thousands of years as a spice and medicinal herb! The most famous Indian dish, curry, is where turmeric stands out. Turmeric is what gives curry its yellow color.

 Turmeric really does contain compounds that have medicinal properties, as scientists have recently discovered. These compounds are bioactive and are called curcuminoids with the most important one being curcumin. It is the main active ingredient in turmeric and has very powerful anti-inflammatory effects and is also a potent antioxidant.

 Turmeric contains only about 3% curcumin, by weight. The studies that have found curcumin to be so anti-inflammatory used turmeric extracts that concentrates the curcumin to over 1 gram a day. This is very hard to reach just using turmeric as a spice in your food. Therefore, to see the anti-inflammatory and antioxidant effects of curcumin, you’ll need to take a supplement. In addition, it’s best to eat black pepper with your supplement to better absorb the curcumin (by 2,000%!).

Curcumin: Natural Anti-Inflammatory Compound

 Scientists believe that chronic, low-level inflammation plays a huge role in most of the chronic, Western diseases we see today. These include cancer, metabolic syndrome, heart disease, Alzheimer’s and other degenerative conditions. All of these are pretty scary diseases and it’s wonderful that we’ve found a compound that combats chronic, low-level inflammation effectively.

 In fact, curcumin is so powerful, it matches the effectiveness of some anti-inflammatory drugs, but without the side effects! Great news!

Specifically, curcumin blocks NF-kB, a molecule that travels to our cells, to our nuclei and turns on genes that are associated with inflammation. Take some curcumin and stop that sucker in its tracks!

Turmeric Improves Antioxidant Capacity

 Free radicals, the highly reactive molecules that wreak havoc on our bodies, are presumed to be behind aging/premature aging and multiple diseases. These molecules damage our cells and DNA, reacting with organic substances such as fatty acids.

 We need antioxidants to protect us from these free radicals. Thankfully, we have plant foods – veggies and fruits – that are chock full of antioxidants. In addition, we also have curcumin which is VERY potent, neutralizing free radicals on its own while also boosting the activity of your body’s own antioxidant enzymes. Win-win!

Curcumin Boosts Brain Function

 We now know that brain cells (neurons) are capable of forming new connections well past childhood, even multiplying and increasing in number. A neurotrophic factor called BDNF is a type of growth hormone of the brain. Diseases such as Alzheimer’s and depression have been linked to low levels of the BDNF hormone.

 The good news is that curcumin is capable of increasing the levels of BDNF in the brain, possibly delaying or even reversing brain ailments and cognitive decline. Curcumin could also improve your memory and make you smarter.

Curcumin certainly sounds amazing, doesn’t it? If you have history in your family of any of the diseases or ailments discussed in this article, consider seriously getting a good curcumin supplement and adding turmeric to your diet. The science certainly backs up many of these claims discussed here, especially with curcumin supplements. Nobody wants to experience Alzheimer’s, cancer or heart disease so be proactive and consider all possibilities of prevention!



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