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Written by Dr. Welsh, Article reviewed and edited by Dr. Fine M.D..
Published on 27 January 2016

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U.S. OLYMPIC TEAM MEDIA SUMMIT PRESS CONFERENCE Participants: Brian Clay (BC) Walter Davis (WD) Lashinda Demus (LD) Allyson Felix (AF) Reese Hoffa (RH) Carmelita Jeter (CJ) LaShawn Merritt (LM) Terrence Trammell (TT) Quotes:

Q: Brian, can you give us an update on your health?

BC: So far, everything is going just as planned. Before the 2004 Games, I had a personal best in the heptathlon leading into Athens. Again, this year I had another personal best and hopefully Ill taking everything I have done so far and taking that into the Games. I expect my health to be fairly good. I have had a few colds here and there, but other than that, things have been pretty good.

Q: Reese, does your dexterity translate from Rubix cube to sport? What will it take to make the team?

RH: With the Rubix cube, I just do it for fun. It doesnt really help anything. It actually hinders my throwing. Back in 2004 Olympic trials, I couldnt fully extend my arm and I barely made the team because of it. I basically do this for show, try to make people think I am smart... Why are you laughing? I am trying to be serious here. To make the team, especially this year, I just have to go out there and take care of business. Just do what I have done with the previous years in 2006 and 2007.

Q: LaShawn, were you surprised Jeremy Wariner changed coaches?

LM: I think it was a surprise to everyone that he changed coaches... He knows how to execute the race. It is his job, I dont think he would make a bad move.

Q: Lashinda, what are the logistics with managing your twins?

LD: I dont manage. They manage me. They rule me. I have no control. Its hard. I wanted to quit about a millions times. I am ready now. I was a Toyota and now I am a Maserati.

Q: Allyson, talk about your 100 meters focus? Carmelita, your evolution into the upper echelon of track?

AF: This year I am trying to focus more on the 100 meters. I would like to run it in the Olympics. My main focus is just the start; if I can get that down I can be very competitive in it. I also love the race. I love the speed. I am looking for good things come trials.

CJ: I am more 200/100 and I have been running for awhile. I graduated in 04. I had a reoccurring hamstring injury that hindered me from being able to show the world how I can run. Now I am healthy and I am ready to run.

Q: With the recent focus on doping, do you feel pressure to reclaim the image of track & field?

AF: I think we all know that our sport has taken another unfortunate step backwards. I think that we are all in agreement that it is our responsibility to shed some light back on our sport and I think we can do that by some amazing performances in Beijing. That is our top priority. I think that we all want people to see where we came from, to recognize the hard work we are putting in and to recognize that.

Q: Do you feel pressure to match historical greatness?

CJ: I dont feel any pressure. I am just going to go out and run my race. That is what is important to me. I am just going to go out and run my race.

AF: I think that, you know, you kind of feel the added pressure, but I think we can be proud of where we came from, the people who have come before us. We dont want to let anyone down. I think that will motivate us more, because we know our reputation is on the line.

Q: The USOC emphasized a clean team, and that youve seen the shame of doping violaters. How has it impacted you? Are you confident it is a clean team?

TT: I think the biggest thing that has happened is that it has put a cloud over the entire sport based upon the amount of press that is focused on drug use. I think that there are several different aspects of track & field... I think that with light being shed more toward the positive things of track & field, not just the Olympic year and I think that would help put the sport in a better light. I think that people make their individual choices based on what they feel or believe. I cant walk in the next mans shoes. All I can do is represent myself, my country, and my community the best that I know how.

Q: Can you speak about the Liu Xiangs pressure?

TT: I think he will be under an extreme amount of pressure. He is holding a nation on his shoulders. They are all watching him. I cant fathom 1.3 billion people anywhere in the world. That being the case, the one thing that I think that they are taking too far is the expectations. They are no longer hopes, they are expectations. It is a different ballgame when you have hope and when you have expectations. So he is going to be under a lot of pressure.

Q: With a trial scheduled for next month where names may be revealed, can track & field deal with another shadow?

BC: Well any time someone tests positive in track & field, it is a major blow. It can be during trials, during the Olympics, during Christmas, whatever, it is even more of a blow to the athletes trying to do it the right way. Because there are definitely things like sponsorship opportunities that does take away from trials and the other meets we have to do well at to make a living. Of course it is a hindrance, and quite frankly it sucks, to take away from what we are doing to do it the correct way. Our job is to compete to our best ability and to put our best foot forward and to try to represent U.S. track & field to the best of our ability. I think that is what we are all trying to do... We are going to put on the blinders and focus on our race... To let people know, this is the real US team here and this is our

Q: Lashinda, what elements came easy as you returned?

LD: It was actually harder for me to get my technique post-babies. I am stronger, not because I had the babies, but because I worked 10 times harder to get back to normal. I am ahead of schedule. I dont think my technique is any better than it was; I am just stronger.

Q: How has experience in other Olympics helped?

WD:Yes, I think the two Olympics before was experience. As they say, the third time is the charm. So as I go to Beijing, I hope that is the case. Yes, I will try to compete in both jumps...You cant triple jump and long jump at the same time. Since the long jump is first, I am going to try and do both again.

Q: With talk about doping, do you feel you have to prove you are clean?

BC: For me, any time I can get the opportunity to let someone know I am clean, I take it. I have had the most recent opportunity to... The USADA just started a program where they pick a few athletes that they are going to test a lot. Basically the point of Project Believe, their goal is to try and prove that athletes are clean instead of always proving athletes are dirty. I am a part of that. I have been tested, I cant tell you how many times. I went through a two week period where I was tested 11 times, blood and urine, with five vials of blood each time and urine tests. I have another round coming up. I am tested randomly more than the normal athlete. I will be doing blood and urine tests 2 times a month, up until the Olympic Games and through the Olympic Games. Plus I am being tested at meets I go to randomly, and I am still in the WADA pool. Any time I get to prove it, I try to take that chance. I know that there are questions. People are always asking questions, because of what is coming up in the News.

Q: Do you feel confident now that the U.S. will take a clean team to Beijing and that athletes are clean in your event (from other countries)?

RH: I have to believe that every athlete I will be competing against will be clean. I cant speak for every athlete. I know here in the U.S. we are definitely taking a lot of steps to make sure... That we are all extremely clean. The shot-putters in particular because I think we have more athletes ranked higher in the world. So, they kind of put us on a higher priority list. I have to believe we are all definitely clean. If for some reason that would happen to us, that we end up testing positive, the ramifications would be devastating to the sport in the U.S. Hopefully, any of the future athletes know that we like where shot-putting is in the past and in the world. We want to make a career of it.

Q: HGH blood test. How feel about having to test HGH blood tests versus other sports not having to i.e. football, baseball, etc.?

TT: We have been through this several times before. I dont think we need to panic or end all be all. I think my first one [HGH blood test] was in 2005 so that is nothing new. However, when you get to talking about specific dynamics about that attention, you have to also talk about the marketability and the perception of these sports. You have billion dollar industry in these other sports. I think with track & field, we are better athletes; we work a whole lot harder. I think we do tend to get the short end of the stick. The reason I brought up the money issue, it would appear to me, that with so much riding on those other sports, they wont let things tarnish their investment. It is something we are dealing with it and it is a shame. I would take it upon myself that everyone on this panel is doing it the right way. We take pride in that we earn it is what we get.

Q: Speak to your involvement in frequent drug testing, Marion Jones, and what do you think of her in jail?

AF: Well, I will talk about the Marion Jones thing first. It was around the year 2000 when Marion was everywhere; she was definitely someone I looked up too. It was personally devastating for me see that it was true and see her go through that. I guess I felt even more responsible to be a role model to younger kids because that was important to me. It would be great if my role model could have been clean and still been my role model. And now looking forward, I think that put the light on track & field once again. I am also part of the Project Believe which is an intense program where you are tested about two weeks for a period of time, with five vials of blood like Brian said, and urine and all of that. I feel that I will do whatever I have to do to prove I am clean. I am willing to do it no matter what I have to wake up. I am against doping.

Q: Allyson, what is the trickiest part of the multiple event schedule you are trying to pull off?

AF: I think the most difficult thing is the preparation, just to make sure your body can handle that number races in that amount of days and I am very confident that my coach, he has done it before, and I know he can do it again to get me to that level. Right now I am focused on the trials, I mean I need to get through those first before I try to schedule everything out. That is my main focus now.


Written by Dr. Welsh, Article reviewed and edited by Dr. Fine M.D..
Published on 01 December 2012

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Human Growth Hormone Declines with Aging

The decline of growth hormone with age is directly associated with many of the symptoms of aging, including cardiovascular disease, increased body fat, osteoporosis, wrinkling, gray hair, decreased energy, reduced sexual function and interest, and other ageing archetypal symptoms. Many of these symptoms have been found in younger adults who have growth hormone deficiency.

Research over the last 40 years confirms the decline of Real Injectable HGH as we age in our adult years and the decline of Real Injectable HGH production accelerates as we it is theorized we get older, therefore as we get older after the age of 30 our bodies are not stimulating the regenerating new healthy cells as fast as they are dying off, and as a net result, aging seems to be the process of our bodies slowly dying faster than it can replace itself at first and the dying process accelerates as we continue age.

HGH Levels in Life

Real Injectable HGH is produced at a rate that peaks during adolescence when accelerated growth occurs. Growth hormone secretion decreases with age in every animal species tested thus far. In humans, the amount of growth hormone after age of 25 to 30 declines about 14% per decade (or 1% to 2% per year), so that total daily growth hormone production is reduced dramatically with age. In numerical values, we produce on a daily basis about 500 micrograms of growth hormone at age 20, 200 micrograms at age 40, and 25 micrograms at age 80.

Age 40+

At age 40 our growth hormone production is only 40% of what we produced at age 20. The fall in IGF-1 levels with age is identical to the decline of growth hormone.

Another research has shown that by the age of 40, our Real Injectable HGH production is down to 50% of youthful levels. By the age of 55 it sinks to 20%, which is not much more than someone in their 80's can produce.

Human Growth Hormone Decreases Significantly after the age of 35 to 45. Scientists do not know the exact reason why persons over the age 35 to 45 tend to incur such a significant decrease in Real Injectable HGH growth hormone secretion from the pituitary gland, with the result causing symptoms of aging, andropause ie Doctor Prescribed HGH deficiency.

Some medical research has revealed that the aging pituitary somatotroph cells can still secrete as much growth hormone as the young somatotrophs cells if they are properly and adequately stimulated. As a result some researchers have come up with several theories regarding aging resulting from Real Injectable HGH related deficiency.

HGH Blockers Increase with Age

Real Injectable HGH Blockers” (called Somatostatin) increase with age
Some research scientists believe the problem lies with somatostatin (HGH blockers”), the natural inhibitor (blocker) of Real Injectable HGH. Somatostatin has been found to increase in population within the body with age and may act to block the pituitary’s release of Real Injectable HGH. When researchers eliminated somatostatin production in old rats, they found growth hormone secretion as great as those of young rats. This might indicate theoretically the Pituitary Gland has a life long ability to produce any healthy level of Real Injectable HGH we might desire.
Real Injectable HGH Stimulators Decrease with Age

Growth Hormone Releasing Hormone

A second theory is that the precursor hormone, growth hormone-releasing hormone (GH-RH), which stimulates HGH release by the pituitary gland, becomes less sensitive to signals from the hypothalamus. Hence, insufficient GH-RH is released resulting in a decrease of growth hormone secretions over time and age.

Decreased Ability to Process HGH

The Body Requires More Real Injectable HGH as we Age or the Body loses its ability to utilize Real Injectable HGH as we age

A third theory is that, not only does the growth hormone secreted and available to receptors in our cells decrease with aging, but that the cell receptors become more resistant and less responsive to the human growth hormone. Under this theory, aging can be viewed as a disease of growth hormone resistance within our cell receptors similar to the way in which diabetes is a disease of insulin resistance

See: HGH Deficiency Test


Written by Dr. Welsh, Article reviewed and edited by Dr. Fine M.D..
Published on 19 November 2012

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OmniTrope®: bio identical hormone therapy

OmniTrope somatropin [derived from recombinant DNA] is a specific hormone made up of polypeptide bonds. It consists of 191 residue amino acids, and it has a molecular weight of 22,125 daltons. The sequence of amino acids in this product is a bio identical hormone to that of Human Growth Hormone that originates in the pituitary (somatropin). Omnitrope is through a modification of a strain of E. coli to include the gene which is responsible for Human Growth Hormone. OmniTrope comes in the form of a white, sterile powder, lyophilized (freeze-dried) and intended for injection subcutaneously.

OmniTrope 5.8 mg is in a vial which contains 5.8 mg of the Growth Hormone somatropin (about 17.5 IU), Sodium phosphate monobasic dihydrate (0.56 mg), Sodium phosphate dibasic (2.09 mg), and glycine (27.6 mg). This product comes with a vial which contains 1.14 dilutant (Bacteriostatic Water for Use in Injection which contains 1.5% preservative benzyl alcohol). After the lyophilized powder has been reconstituted,, the total solution has a 5 mg/mL concentration (About 15 IU/mL).

OmniTrope 1.5 mg is in a vial which contains 1.5 mg of somatropin (about 4.5 IU), Sodium phosphate monobasic dihydrate (0.21 mg), sodium phosphate dibasic (0.88 mg), and glycine (27.6 mg). This product comes with a vial which contains 1.13 dilutant (water sterilized for injection). After the lyophilized powder has been reconstituted, the total solution has a 1.33 mg/mL concentration (About 4 IU/mL).

The osmolality of the solution of reconstituted somatropin is about 300 mOsm/kg. It has a pH of around 7.0. Concentration of OmniTrope is dependent upon presentation and strength (For more information, see How Supplied).

Clinical Pharmacology

Clinical, preclinical, and in vitro tests show that OmniTrope is equivalent to Human Growth Hormone that originates naturally in the pituitary in terms of therapeutic results. The body reacts in a similar fashion to Omnitrope as it does to the HGH created internally in the average adult. OmniTrope therapy in child patients who suffer from a growth hormone deficiency (GHD) succeeds in stimulating normal growth and balances concentrations of Insulin-like Growth Factor (IGF-1).

Omnitrope bioidentical hormone replacement therapy treatment in adults who are with Growth Hormone Deficiency often results in a lower level of body fat, an increased amount of lean muscle mass, and changes in metabolism which include positive changes in the metabolism of lipids and the balance of concentrations of Insulin-like Growth Factor-1.

Also, many other results have been shown through the administration of somatropin and/or Omnitrope, including the following effects of hormone replacement therapy:

1. Tissue Growth

A. Skeletal System Growth: OmniTrope bio identical hormone has to stimulate the growth of the skeletal system in young patients who suffer from Growth Hormone Disorder. There is a significant increase in the length of the body through the use of OmniTrope which results from its effect upon the epiphyseal plates which develop inside the long bones. Serum levels of Insulin-like Growth Factor-1, which likely play a part in the growth of the skeletal system, are to be usually quite low in young patients suffering from Growth Hormone Disorder. These levels increase when the patient undergoes Growth Hormone Replacement Therapy with Omnitrope. Higher serum concentrations levels of alkaline phosphatase also are caused treatment. This chemical aids in the breakdown and excretion of chemicals in the body.

B. Cell Growth: Research has shown that young, short-statured children have a lesser number of skeletal muscle cells because they have an insufficient level of natural hormone in comparison to the normal child population. Treatment with Omnitrope therapy for hormone imbalance leads to a boost in both the size and number of these muscle cells.

2. Protein Metabolism

Linear, normal growth in childhood is in part facilitated through an increase in the synthesis of cellular proteins. Retention of nitrogen, which is through a decrease in the excretion of nitrogen through urination, as well as through blood test measurements of nitrogen in the urea, is one of the many physiological changes that occur through OmniTrope therapy.

3. Carbohydrate Metabolism

Children who suffer from hypopituitarism often also experience low blood sugar when fasting and this issue are also alleviated through OmniTrope treatment, though excessive doses of Human Growth Hormone can lead to glucose intolerance.

4. Lipid Metabolism

In those who are deficient in Growth Hormone, OmniTrope therapy has to result in the mobilization of cholesterols, allowing for a reduction in storage of body fats and a higher level of fatty acid in the plasma, which provides more healthy energy for the body.

5. Mineral Metabolism

Growth Hormones can also can lead to retention of phosphorus, potassium, and sodium. Concentrations of inorganic phosphate in the blood stream are increased in those patients maligned with Growth Hormone Disorder who go through Omnitrope Hormone Therapy. This is healthy because it allows these phosphates to either be used appropriately by the body or be excreted. Levels of calcium in serum are not in a significant manner through the use of OmniTrope, and Human Growth Hormone can lead to Calciuria.

6. Body Composition

Adult patients who suffer from Growth Hormone Disorder that are with OmniTrope at the suggested adult dosage (view Dosage and Administration for more information) show a decreased level of body fat and an increased level of lean muscle mass. These changes occur at the same time that the body begins to retain fluid more effectively. The result of all of this is that OmniTrope can modify the composition of the body positively, and these positive changes can be sustained through continuing treatments.

Adult Growth Hormone Deficiency

Placebo-controlled, randomized clinical trials using somatropin have been performed in adult patients suffering from Growth Hormone Deficiency.

In these clinical trials, positive changes in the fat and muscle composition of the body were noted after a six month somatropin treatment schedule. These changes were observed in comparison to the placebo group. Total body water, lean/fat ratio, and lean body mass increased as waist circumference and total fat mass decreased. These positive effects that somatropin had on the body were retained when treatment was continued past the original six month period. There was a decline in bone mineral density (BMD) after six months, but BMD returned to baseline levels after a year of treatment.

Indications and Usage

OmniTropin is for long-term therapy of pediatric patients that suffer from growth failure as a result of the inadequate production of naturally secreted Human Growth Hormone. It is not for other causes of short stature.

OmniTropin is for long-term Growth Hormone Replacement Therapy for adults that suffer from a Growth Hormone Deficiency that is of either adult or childhood-onset in its development. Growth Hormone Disorder should be diagnosed through an appropriate GH stimulation test.

Hormone Replacement Therapy Contraindictions: The dangers of hormone replacement therapy for some groups

OmniTrope should not be used if an individual shows any signs of abnormal tissue development. Intracranial spade occupying lesions must be inert and antitumor treatment must be complete before OmniTrope therapy begins. If the tumor begins to grow again, OmniTrope treatment should be discontinued immediately. Also, GH should not be administered as a means to promote growth in children who have fused growth plates in the long bones.

Human Growth hormone treatments should not be administered to provide therapy for individuals who have an acutely critical illness stemming from abdominal or open heart surgery, multiple physical accidental trauma, or to those who have suffered acute respiratory failure.

A pair of clinical trials in which the adult patients were afflicted with these conditions but did not suffer from Growth Hormone Deficiency found that there was a significantly higher incidence of mortality affecting those who were treated with somatropin in comparison to those that merely received placebo (read Warnings for more information).

Prader-Willi patients suffer from a genetic disorder that leads to obesity and low lean muscle mass. Their bodies produce extremely low or nonexistant levels of hormones. If these patients have severe respiratory problems or are acutely obese they may have issues with Growth Hormone Therapy.

OmniTrope treatment is not for any patient who is hypersensitive to the hormone somatropin or any of the other ingredients of OmniTrope.


OmniTrope 5.8 mg preparation contains the preservative benzyl alcohol. It should not be administered to newborns.

Read the Contraindictions section for more information about increased mortality risk in those who suffer from critical illnesses in ICU because of complications due to abdominal or open heart surgery, multiple trauma due to an accident, or those who are suffering from acute respiratory failure. The proper research has not been established regarding the safety of continuing to undergo Growth Hormone Replacement Therapy for those who would be eligible for treatment but also concurrently begin to suffer from the above ailments. For this reason, the possible benefits of Growth Hormone Replacement Therapy in those patients who are suffering from critical, acute injuries must be weighed against the possible risks of undergoing such treatment.

Precautions: Is Hormone Replacement Therapy safe for you?


Therapy with OmniTrope, as well as any other Growth Hormone Therapy, should be guided by a hormone replacement doctor who has experience in the management and diagnosis of patients with Growth Hormone Disorder, as should be the case with the usage of any Growth Hormone preparation.

Caregivers and patients that will inject OmniTrope in situations which are medically unsupervised are to attain proper instruction and training about how to properly use OmniTrope. This training should be given by one of the many bioidentical hormone doctors in your area or any other properly trained health professional.

Side Effects of Hormone Replacement Therapy

Patients who suffer from Growth Hormone Disorder in addition to an intracranial lesion need to visit their doctor with regularity to monitor the development or recurrence of the underlying process of their disease. A survey of pediatric reports regarding the use of somatotropin replacement therapy shows no correlation between somatropin replacement therapy and tumors of the central nervous system. Later in life, there has been insufficient research to discover is there is any sort of causal relationship between the occurrence of central nervous system tumors and somatropin treatment.

It is also vitally essential that patients be carefully monitored for the formation of malignant lesions on the skin.

Caution is if Human Growth Hormone Therapy is to those that are already suffering from diabetes, because the level of insulin intake may need to be changed as a result of the hormone therapy. Those undergoing Omnitrope therapy should be monitored for the development of glucose intolerance, because Growth Hormone can sometimes give rise to a state where one is more resistant to insulin. Those patients that have already had glucose intolerance or diabetes must be particularly closely monitored while taking OmniTrope. Patients that have factors that place them at a higher risk for intolerance to glucose, like obesity and/or a genetic predisposition to Type II diabetes should also be monitored carefully.

With those that have been diagnosed with hypopituitarism (a disease that is the result of multiple deficiencies of the hormonal system), the normal regimen of Hormone Replacement Therapy should be closely monitored when OmniTrope treatment commences. Hypothyroidism (lack of proper secretion of thyroid hormone) can develop as one is with OmniTrope, and as a result, inadequate medical response to hypothyroidism can cause OmniTrope to become less effective or ineffective. For this reason, it is pertinent that patients get tested for proper thyroid function periodically, and if the thyroid becomes less active, thyroid hormone should also be administered in tandem with OmniTrope. Also, testosterone levels should be checked as well, and testosterone injections may be recommended by your Growth Hormone Therapy doctor.

Pediatric patients who have a disorder of the endocrine system such as Growth Hormone Disorder have been shown to have a greater risk of developing a slipped capital femoral epiphyses. Any young patient that develops a limp or begins to complain of knee or hip pain as they undergo OmniTrope therapy should undergo evaluation.

Other side-effects

Patients who experience rapid growth as a result of OmniTrope may find that they uncover an underlying case of scoliosis. Since Growth Hormone boosts the growth rate, those patients that have battled scoliosis in the past that are with Omnitrope should be examined periodically for new progression of scoliosis. Fortunately, there is no evidence that Growth Hormone causes scoliosis.

Intracranial hypertension (IH) is an increase in pressure in the skull which is associated with with nausea, vomiting, headache, visual disruption, and/or papilledema has to be a side effect in a small minority of patients that take Growth Hormone therapies. These issues occur usually within the first two months after one begins GHT. In each reported case, symptoms and signs of Intracranial Hypertension are after hormone therapy is or the dosage is to a more minute amount.

Funduscopic examination should be performed as a patient begins therapy, and it is that they are for Intracranial Hypertension periodically as he or she continues Therapy. This test checks for abnormalities of eye pressure and the veins of the eye. Before undergoing adult treatment for Growth Hormone Deficiency, a patient who has undergone puberty and received GHRT in their childhood needs to be reevaluated in a manner that is in the section Indications and Usage. If it is advisable to continue treatment, Omnitrope therapy should continue at a lower level of dosage that is more appropriate for adults who have Growth Hormone Disorder.

Concomitant Drug Usage

Undergoing treatment with glucocorticoids concomitantly with Growth Hormone can cancel out the growth promotional effect of Hormone Therapy. Pediatric Growth Hormone deficiency patients that have a coexisting deficiency of ACTH (a precursor hormon to adrenal among other hormones) need to have their dose adjusted carefully so that the glucocorticoid does not inhibit the effect of the Growth Hormone Replacement Therapy. For more information, see Precautions. Though there is limited published research on the subject, it has that in humans, GHT increases antipyrine evacuation mediated by CP450 (cytochrome P450). The available data seems to suggest that GH administration can alter the evacuation of the compounds that become metabolized through the liver enzyme CP450. These compounds include sexual steroids, cyclosporine, anticonvulsants, and corticosteroids. It is that a patient undergo careful monitoring when OmniTropin is used in addition to other drugs that are by the liver enzyme CP450.

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