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Written by Dr. Welsh, Article reviewed and edited by Dr. Fine M.D..
Published on 01 October 2017

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Many board certified Anti-Aging and Longevity Physicians believe the governments of the world have a grossly distorted understanding of Human Growth Hormone. HGH is an absolutely natural protein the body produces, and as it declines so does our health.

Sylvester Stallone who is in his 60's looks and feels like he is in his late 30's, his secret? Human Growth Hormone. Sylvester Stallone the star of the latest Rambo flick says human growth hormone is very misunderstood. Story By Mike Celizic from the TODAY Show.com

Rocky Balboa and John Rambo never pulled any punches, and neither does the man who created two of Americas most enduring action heroes. Even when the talk turns to the human growth hormone (HGH) he was convicted of having in Australia last year, Sylvester Sly Stallone doesnt blink. I wish it were true that you could take something like that and get in shape, the movie icon told TODAY co-host Matt Lauer on Friday in New York.

He was in town to pump his new movie, Rambo IV, opening in theaters nationwide on Friday, Jan. 25. Out takes from the film show the action hero with muscles still bulging, his relatively unlined face mocking his 61 years.


Written by Dr. Welsh, Article reviewed and edited by Dr. Fine M.D..
Published on 06 November 2017

Human Growth Hormone Production is Intrinsically Linked to Sleep Quality

Even in the 21st century, sleep largely remains a mystery to modern medical science. Every year, we learn more about the mechanisms of sleepHow it rejuvenates the body and mind to take on another day. To live a healthy and active life, you have to make an effort to schedule for regular, restful sleep.

lack of-sleep

One of the reasons why sleep is so important is because of Hormone Balance. Many vital hormones that are produced by the human body, including Human Growth Hormone, are primarily secreted while we are at rest. The goal of this article is to explain in further detail how Healthy HGH Balance and Good Sleep are connected.

What Makes Sleep So Important to HGH Production?

Medical research hypothesizes that around 3/4ths of the HGH that is produced by the pituitary gland is released during sleep. HGH, like many hormones, is discharged in pulses. The majority of Growth Hormone pulses from the pituitary while we are in the deepest stages of sleep, also known as 3rd/4th Stage REM Sleep, delta, or slow wave sleep. We first reach this stage around an hour after dozing off, and fade in and out for the rest of our time asleep.

It is important that we have high-quality sleep during this phase of the night because HGH Production correlates directly with the amount of delta sleep that we get each night. Healthy HGH Levels are strongly associated with markers of health and vitality. On the other hand, Growth Hormone Deficiency is linked to low libido, reduced mental focus, weight gain, loss of exercise capacity, decreased muscle mass, thinning hair, deep wrinkles, and an increased risk of dangerous health issues such as heart disease and diabetes.

Americans No Longer Get Enough Sleep

In the fast-paced, overstimulated society that we live in, sleep deprivation is becoming an increasingly dangerous risk to men and women nationwide. People aren't getting enough sleep, and even when they do, they often have trouble reaching sufficiently deep sleep to achieve the maximum benefits of such rest. Over the last generation, there has been a notable decline in the average amount of rest per night that Americans get on average. It's estimated that almost 70 percent of men and women in the United States get less than eight hours of sleep per night.

This lack of sleep is also paired with research that shows that quality of sleep is affecting Americans' ability to do their job, with almost 1/3rd of employees physically exhausted at work to the point of nearly falling asleep, or actually falling asleep.

Americans are notable for their work ethic, and pridefully putting in overtime, working multiple jobs, or working and going to school full timebut there are consequences to a lifestyle which pushes the body to its limits. HGH Deficiency is one of the significant issues related to the modern lifestyle.

How Can I Maximize HGH Production Through Sleep?

For many, it's more difficult than it sounds, but the best way to boost HGH Production is to get a full night of good sleep each night. Depending on your age and your activity level, 7-9 hours of sleep is enough for most people.

Many people try to cheat to get a full nights rest. Some people take naps every day; others try to recover from an extended sleep debt by spending their day off in bed. Though there are benefits to recuperating from sleep debt via these methods, they simply don't compare to getting regular deep sleep on a nightly basis.

In the case of HGH Production, spending too much time in bed can even have a negative impact on HGH Production, because Human Growth Hormone Secretion depends on a combination of healthy activity and restful sleep.

Maintaining a set sleeping schedule maximizes HGH Secretion, because of the way that our brains function while we sleep. The brain ebbs and flows through the four stages of sleep, and it takes 3-5 hours of quality rest for our brains to reach delta sleep long enough to produce all of the Growth Hormone that our bodies require. If you keep an irregular sleep pattern, your body may not spend a sufficient amount of rest in deep sleep.

What Health Issues Are Associated With Poor Sleep?

Human Growth Hormone Production begins to wane as we grow older. This is largely because of natural changes which suppress the body's production of an important HGH Precursor known as GH-RH. Though the root of this decline, is genetic, there is also an element related to age-related changes in sleeping habits.

The older that we get, the less productive that the sleep cycle becomes. Sleep becomes more restless, and the brain spends a shorter period in slow wave, delta sleep. Because of that, HGH Levels fall. Sadly, though natural HGH Production decreases in correlation with age, our need for the potent hormone does not, which drastically increases the risk of HGH Deficiency.

obesity lack-of-sleep

Along with the issues directly associated with declining Growth Hormone Production, poor sleep also has a powerful effect on both health and mortality risk. The risk of developing conditions such as Obesity, Type-2 Diabetes, and Heart Disease increase dramatically. Patients with sleeping issues are also more likely to suffer from immunodeficiency, mood disorders, and substance abuse issues. While it's true that we need less sleep the older that we get, research has shown that getting under five hours per night directly contributes to a 15% increase in overall mortality risk.

What Steps Can Be Taken to Improve Sleep Quality?

In recent years, research into sleep science has developed tremendously. There are some medications which show promise in inducing delta sleep in patients with sleep issues, including olanzapine, trazodone, eplivanserin, gabapentin, gabadoxal, and tiagabine. These studies are still in their preliminary stages, however, and more research needs to be done to fully illuminate the benefits and drawbacks of these treatments.

On the other hand, these treatments do appear to improve sleep quality while protecting against the physiological and psychological issues associated with impaired sleep. Most of these drugs are not available without a prescription. If you're interested in utilizing prescription or over- the-counter methods to improve sleep quality, talk to a doctor or pharmacist.

Sleep apnea is also one of the top health issues associated with impaired sleep quality. Sleep apnea is a condition in which your body doesn't receive sufficient airflow to help you stay asleep, leading to brief periods where breathing becomes shallow or even stops. If you feel that sleep apnea may be holding you back, reach out to a sleep specialist for help.

Natural Methods to Improve Sleep Quality

coffee will-keep-you-awake

While there are medical and pharmaceutical methods to promote sleep, there are also a lot of natural things that you can do on your own to help you sleep sounder and deeper. For example, think about buying a sleep mask, or blacking out your bedroom to block out excess light. Also, light exercise such as tai chi or yoga has been shown to be beneficial. While these activities can help you sleep, you should avoid strenuous exercise or anything that gets your body worked up before bed. Along the same lines, a big part of sleeping better is cutting off certain activities when it comes time for bed. Avoid caffeine, cigarettes, and alcohol in the hours before bed.

Sleep Better/Live Better!

Remember that your hours at rest facilitate your overall vitality. To feel and look your best you should take all of the necessary steps to make sure that you sleep as well as you live! By sleeping well, eating well, and exercising, you should be able to sustain your HGH Levels for as long as possible! When your efforts no longer produce sufficient results, consider Hormone Replacement Therapy! Our Board Certified Hormone Clinic is here to serve you!


Written by Dr. Welsh, Article reviewed and edited by Dr. Fine M.D..
Published on 06 May 2013

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Potential Changes in Patent Law Line Lobbyist Pockets

A Congressional war is being waged in America's capital regarding whether drug manufacturers should

have the right to retain patents which they acquired by breaking the rules or engaging in unscrupulous misrepresentation. This matter of contention has created a muddled legal climate in regard to efforts to reform the existing patent structure.

In a number of recent court cases, judges have reneged on patents after it was discovered that the companies that acquired particular patents misled the Patent and Trademark Office in order to obtain a patent that they did not deserve. Patent law legislation affects a huge portion of the United States economy, and the current affair has left lobbyists both for and against patent law reform with flush pockets. Over the past fifteen months, two corporate coalitions have been in a fierce battle for the ears of members of Congress, spending a total of $4.3 million dollars making their cases both for and against patent law reform.

New Changes in Patent Law Up for Debate

The changes which are up for debate at this time represent the most massive potential overhaul in American patent law in the last half-century. Corporate representatives from nearly every significant United States industry have thrown their hats into the ring. Currently, patents give their owners the rights to their invention for a period of up to twenty years. As a means to defend against illegitimate patents, Federal courts have the jurisdiction to cancel patents if they discover that corporations acquired their patent through nefarious means, such as hiding or misrepresenting data in order to trick the patent office into issuing an unwarranted patent. If a patent has been found to have been earned in this manner, a federal court can nullify the patent, canceling its validity.

Senior V.P of the pharmaceutical manufacturer Eli Lilly, Robert Armitage, believes that this form of nullification is a miscarriage of justice. He compares it to sentencing a person to death for a simple misdemeanor. In his eyes, it's simply a gross misuse of force. Pharmaceutical companies that deal in Trademarked drugs are lobbying Congress in order to soften or eliminate this penalty for misconduct as it is currently encoded into law.

Debra Barrett is a the primary representative speaking for generic pharmaceutical companies. She is the V.P. Of the American arm of Teva Pharmaceutical, which is the biggest generic medicinal manufacturer on earth. She argues that the changes lobbied for by the designer pharmaceutical companies would create an unfair playing field in which drug companies that deal primarily in patented drugs would have an unfair advantage which essentially gives them a blank check to deceive the market. This change in patent law would make it easier for companies to retain ill-gotten patents and prevent useful and lifesaving drugs from reaching the generic market in a time frame that is supposedly ensured by law.

Consumer Advocates Weigh In

In addition to generic drug companies, consumer advocate organizations such as the American Association of Retired Persons are also concerned about the abuse of patent law which they feel has the potential to hurt customers. Groups like the AARP are ultimately concerned with ensuring that drugs enter the generic market at a timely pace. These generic drugs can be up to eighty percent cheaper than their trademarked counterparts. The AARP understands that there are many forms of therapy such as HGH Hormone Replacement Therapy and other health treatments which can potentially provide incredible benefits to seniors, and the earlier that these drugs are made available to the generic market, the more seniors will have the opportunity to utilize such therapies.

Current Activity in the House and Senate

The House of Representatives ultimately sided with the brand name pharmaceutical manufacturers and have passed a bill that would decrease the judicial systems ability to nullify patents for reasons of misconduct. The Senate has yet to come to agreement on a similar bill which was presented by the Senate Judiciary Committee, but it is expected that the bill will reach the floor of the Senate in the summer of 2008.

The Recent History of Inequitable Patent Conduct

From 1993 to 2008, the judiciary construct responsible for patent law cases, known as the U.S. Federal Circuit Court of Appeals, has discovered proof of misleading conduct in at least forty cases that were brought to trial. Among these cases were fourteen cases which involved health care and pharmaceutical patents. District court justices have also come to find similar results in an unidentified number of patent law cases in which appeals were not sought. In these cases, the courts discovered that pharmaceutical manufacturers presented knowingly untrue statements to the United States Patent Office in which they hid contradictory evidence and purposefully explained their experiments in a manner which was selectively inaccurate.

In one particularly telling case, the U.S. Court of Appeals explained that the drug manufacturer Novo Nordisk purposefully lied to the patent office regarding an experiment which they claimed to have performed when making the case for their patent for a form of Bio-Identical Human Growth Hormone. In a similar case, the drug company Pharmacia produced a misleading and inaccurate sworn statement when seeking a patent for a glaucoma drug.

Brand Name Versus Generic

Trademark drug companies accuse generic pharmaceutical manufacturers of being over-litigious, attacking patents haphazardly even if there is no proof of inequity, or unfairly targeting cases which unintentional but minor mistakes were made in patent acquisition. The brand name pharmaceutical manufacturers believe that aggressive claims of iniquity have become a major hindrance on the normal activity of the patent system. One of the primary interest groups that lobbies from this perspective is a trade association known as the Biotechnology Industry Organization. The BIO represents drug manufacturers that research modern medical treatments such as Testosterone Replacement Therapy and other patented Hormonal Therapies, among various other pharmaceuticals.

A Presidential Advisor Weighs In

The commissioner of trademarks and patents under George H.W. Bush was Harry Manbeck Junior. He believes that the current legal construct regarding patent inequity is a needed and sufficient deterrent to prevent unscrupulous patent conduct. He believes that it is important to recognize the potentially immense value of the patent. He goes on to say that companies have powerful incentives to acquire them, and that even with the current nullification structure in place, certain corporations still occasionally make the conscious decision to subvert the law. Mr. Manbeck maintains that the doctrine of inequitable conduct is a necessary construct which helps weed out the existence of ill-gotten patents.

How the Current Law Works

Under existing national regulations, individuals who seek to attain patents have an obligation to be honest when interacting with the United States Patent Office. They are required to speak with honesty, good faith, and candor. Patent-seekers are required to tell patent office officials if the invention which they present was first used by some other individual or entity, or if the invention was previously discovered by some other individual or group. They are also required to disclose whether the product has been put up for sale or delineated previously in some form of publication. If any of those circumstances are true, the patent office may make the decision that the patent sought is not original enough to be approved.

The Opinion of the Patent Office Professional Union

Although the patent office makes reasonable efforts to uncover existing forms of any potential patents presented to them, it is impossible for officials to review all of the relevant information in its entirety due to the volume of such information. For this reason, it is of the utmost importance that applicants be honest and upfront with all of the information that they have unveiled. Robert Budens is the executive officer representing the Patent Office Professional Association. This organization is a union which represents the needs of over 5,500 patent examiners across the United States. He believes that the patent inequity laws on the books are vitally important to the underlying purpose of the United States Patent Office, which is to protect the intellectual property of individuals who engage in genuine innovative activity. Weak patent inequity laws undermine this underlying purpose.

Some Consider Abuse inherent in the Current System

On the other hand, the executive representing Eli Lilly, Mr. Armitage, argues that the rules regarding inequitability are being abused by individuals and companies who wish to nullify legitimate patents for their own gain. The doctrine of inequibility is being cited with such frequency that it is creating an entire set of unintended consequences.

The executive officer of the BIO, James Greenwood, laments the plight of the overwhelmed patent official, claiming that individuals have a tendency to provide mountains of non-vital information to the United States Patent office in an attempt to avoid being perceived as hiding any information. In addition to this, they do little to explain the information that they provide to the patent officer because they fear that they will accidentally be misconstrued as having misrepresented the information they provided to the patent office. In the end, Greenwood claims, the examiner of the patent is forced to read through reams of information provided by the patent applicant with no guidance whatsoever as a result of the strict laws in place regarding inequitable conduct.

The Modern Surge of Patent Applications

Applications for patents have grown exponentially in the past two decades. A total of 467,243 patents were applied for in the year 2007. This number is twice the number applied for in 1997 and three times the number applied for in 1997.

The Undersecretary of Intellectual Property Commerce, Jon Dudas, says that there aren't more inventions than their were twenty years ago, there are more false leads and ideas which are unpatentable. The quality of the applications has dropped precipitously in the last generation.

Over the course of the last forty years, the fraction of applications which were approved for patent existed in a range of 62%-72%. In the year 2000, the percentage of successful patent applications peaked at 72%, but eight years later, the number of actionable patents has dropped to only 43% in the first business quarter of 2008..

Why is Patent Law Important To Technological and Pharmaceutical Companies?

One of the major reasons that existing patent law is at risk is because technological companies have an innate desire to restrict legal costs and damage settlements that occur when patent infringement is discovered. Corporations such as Palm and Cisco claim that these legal quarrels drain precious funding that would better serve both corporations and Americans at large if invested in innovation and research.

New Lobbying Firms Arise

A new lobbying firm has coalesced as a result of the unified needs of these patent-driven tech companies. This firm is known as the Coalition for Patent Fairness. Over the past five business quarters, the coalition has spent over $2.5 million on a large retinue of lobbyists which represent both Democrats and Republicans. The primary Democratic representative Democratic strategist Steven Elmendorf. The primary Republican representative is Mark Isakowitz.

A similar lobbying group known as the Coalition for Twenty-First Century Patent Reform has also formed, which represents fifty corporations which defend their patents and trademarks with zeal. These corporations have classically been known for their propensity to file lawsuits in defense of their existing patents. This coalition includes biotechnology companies and pharmaceutical companies such as Pfizer, Merck, Eli Lilly, and Genzyme. This group of corporations has spent almost $2 million dollars funding lobbyists working in their favor. The biggest recipient of money from the coalition is a legal team administered by Akin Gump.

Patent law plays a major role in medical and technological innovation, and hopefully in the near future, laws will be both improved and streamlined in order to optimize the relationship between medical innovation and improved health outcomes for Americans.

Information Collected from www.newyorktimes.com

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