WHAT IS ADRENAL FATIGUE
Written by , Article reviewed and edited by Dr. Fine M.D.
Published on 21 June 2014
What is Adrenal Fatigue, and How Does It Impact Physical and Mental Health?
Adrenal Fatigue is a medical condition that occurs when the body's ability to produce adrenal hormones is suppressed, preventing the body from functioning optimally. The body has a limited ability to produce certain hormones over time, and if the body produces too much of certain hormones over an extended period of time, it can sometimes no longer meet the needs of the body.
What Causes Adrenal Fatigue?
Adrenal Fatigue has many causes, and most are related to any issue which chronically puts physiological stress upon the body. High levels of psychological stress can lead to Adrenal Fatigue, as well as constant stress over a long period of time. Adrenal Fatigue can also occur as a result of physical stress from a variety of sources, including pneumonia, bronchitis, the flu, and chronic infections. Respiratory System infections are more likely to lead to Adrenal Fatigue than other forms of infection.
Adrenal Fatigue Is Caused By Exhausted Adrenal Glands
The primary symptom of Adrenal Fatigue is the reduced function of the Adrenal Glands that does not see improvement, even with sufficient rest. Adrenal Fatigue is a complex condition that is associated with a number of different disorders. Think of it as a symptom of other issues that are causing problems for the body or mind.
Adrenal Fatigue often goes undiagnosed, and people often mistake the symptoms of Adrenal Fatigue for psychological symptoms such as mild depression, exhaustion, or a general lack of well-being. People that have Adrenal Fatigue will often try to self-medicate their condition subconsciously by drinking a lot of cola or coffee or using stimulants to keep themselves energized enough to get by.
What Are Other Terms for Adrenal Fatigue?
Over the course of the 20th Century, Adrenal Fatigue has gone by a number on names, including Adrenal Apathy, Adrenal Neurasthenia, Neurasthenia, Sub-Clinical Hypoadrenia, and Non-Addison's Hypoadrenia. There are millions that suffer from Adrenal Fatigue in the United States and across the globe, but the condition is not distinctly considered a medical syndrome by most medical groups, and is simply considered a collection of connected symptoms.
How Can Adrenal Fatigue Impact My Life?
Adrenal Fatigue can significantly impact both your health and your general sense of well-being. Although the excess production of Adrenal Hormones such as Cortisol can have detrimental impacts on your health and wellness, so can too little of these hormones. Adrenal Hormones activate your body, getting you ready to seize the day, but they are not intended to remain at high levels 24/7.
Adrenal Hormone Production also spikes when you reach an impasse where your body activates the fight-or-flight response, helping you make split second decisions that could benefit you or even save your life. Obviously, nature never intended for Adrenal Hormones like Cortisol to remain at elevated levels for an extended period of time, and your Adrenal Glands eventually wear down and can lose their ability to produce enough of these hormones when they are actually needed.
In the case of severe Adrenal Fatigue, it can become difficult to even rouse yourself from bed for more than a brief period each and every day.
Adrenal Fatigue is a condition which can increase in severity over time, causing the symptoms to become more problematic. Every system of your body is impacted by diminished Adrenal Hormones, and this effects the core functions of your body. It can diminish your libido, strain your cardiovascular system, affect electrolyte and fluid balance, slow down protein synthesis and cause you to gain weight more quickly. It can also lead to diabetes and other conditions related to carbohydrate balance.
When your body doesn't produce enough Adrenal Hormones, your various systems and organs have to adapt to this biological change, and function at a sub-optimal level. Your body can function in a state of Adrenal Fatigue, but health will deteriorate in a number of different ways at the same time.
What Is the Underlying Cause of Adrenal Fatigue?
The definition of Adrenal Fatigue is quite simple, even though its causes are quite complex. Adrenal Fatigue simply means that the body is no longer producing enough Adrenal Hormones to keep up with the stress signaling of the body. If stressors are controlled, the body can boost Adrenal Function and regain Adrenal Hormone Balance, restoring the body to an enhanced state of Homeostasis.
The Adrenal Glands are responsible for the response to all forms of stress, whether they be psychological, emotional, or physical. When the Adrenal Glands activate, it leads to a cascade of hormonal changes which improve the body's ability to manage stress. Among the functions that are influenced by increased Adrenal Hormones are muscle tone, heart rate, immunity, and metabolism.
As we said, Cortisol and other Adrenal Hormones are activated under all forms of stress, whether you are defending yourself in a fight, mourning the loss of a loved one, fighting the flu, or just worried about your job. If the amount of stress that you experience is overwhelming, then you will start to tax your Adrenal System and will have physiological issues related to Adrenal Fatigue.
In a state of Adrenal Fatigue, you are still able to produce Adrenal Hormones, just not as much as your body needs to preserve normal function. Over-stimulation negatively impacts your Adrenal Health, and this leads to Hormone Imbalance which negatively impacts your health.
Adrenal Fatigue can be caused by chronic stress, or by single events that put a tremendous strain on your body or mind.
Who Is Most Likely to Experience Adrenal Fatigue?
Adrenal Fatigue is a condition that can affect anyone at any age. This condition is a stimulus-response at its core, and it doesn't matter how healthy you are, psychological stress and illness can put the weight of Adrenal Fatigue on your shoulders. Our Adrenal Glands have a limited capacity at any age or in any health state.
Although Adrenal Fatigue can happen to anyone, there are a number of environmental factors that can increase the risk of Adrenal Fatigue, including:
How Prevalent is Adrenal Fatigue?
Because Adrenal Fatigue isn't clinically recognized as a unique disorder, and is usually lumped in with other medical conditions, there is not sufficient data to say exactly how many people today suffer from the condition, although it can safely be considered to be at least somewhat common, if not more so.
In the late 1960s, a physician named Dr. John Tinterra was an Adrenal Specialist who was clinically active in the treatment of diminished Adrenal Function. He explained that, in the late 1960s, more than one in seven people were struggling with severe Adrenal Fatigue, although a much greater number of people were dealing with at least minor issues related to Inhibited Cortisol Production.
How Do I Know If I am Suffering From Adrenal Fatigue?
There are a number of symptoms associated with Adrenal Fatigue. Because Adrenal Fatigue is a complex disorder, it is the collection of symptoms which indicates the condition, rather than any particular, single symptom. Answer the following questions:
Do you feel exhausted with no clear cause?
Is it hard for you to rouse yourself from bed, even when you got adequate sleep the night before?
Do you have trouble recovering from illness or stress?
Do you frequently crave sweets and salty foods?
Do your energy levels peak during the late evening?
If you answered Yes to more than one of these questions, there is a significant chance that you may be suffering from Adrenal Fatigue, and you could greatly benefit from seeing a qualified, licensed medical professional regarding your health and hormone balance.
What Are Some Medical Conditions Commonly Related to Adrenal Fatigue?
Any medical issue that causes high levels of physiological stress can lead to Adrenal Fatigue. Patients experiencing chronic medical issues such as cancer or arthritis are particularly susceptible to depleted function of the Adrenal Glands. If you are suffering from a chronic medical condition, and you find it very difficult to get up and about, there is a very high likelihood that Adrenal Fatigue is affecting your energy levels.
There are also medications that can suppress adrenal activity, such as corticosteroids. Corticosteroids are synthetic hormones which imitate the function of the Adrenal Hormones, and the body will produce less of its own Cortisol and other hormones as a direct result. They are generally prescribed when the body is not producing sufficient Adrenal Response, but once treatment has been suspended, it can lead to symptoms of Adrenal Fatigue.
Adrenal Fatigue and Human Growth Hormone
Adrenal Fatigue can lead to HGH Deficiency if left untreated. The body primarily produces Natural Human Growth Hormone during sleep and during intense physical activity. Because Adrenal Fatigue can sap the body of energy, it is no longer as simple of an endeavor to go out and get sufficient exercise. Also, Adrenal Fatigue has a tremendous impact on sleep quality, which often prevents sufferers from reaching the deep phases of sleep necessary to encourage sufficient HGH Production.
For Patients suffering from HGH Deficiency or Hypopituitarism, Injectable HGH can alleviate the effects of the condition and improve Adrenal Balance, improving overall health.
Adrenal Fatigue and Testosterone in Men
Adrenal Fatigue is associated with a number of symptoms that can contribute to Low Testosterone. Clinical research shows that men that experience Adrenal Fatigue are more likely to suffer from Testosterone Deficiency. This is because Cortisol and Testosterone are both steroid hormones, and are both built from the same ingredients. If the body has been producing high levels of Cortisol, then the body no longer has enough raw ingredients to produce the sufficient amount of Testosterone to meet the needs of the body.
Testosterone Deficiency exacerbates the symptoms of Adrenal Fatigue, and the opposite is also true. This can lead to drastic changes in metabolism which lead to weight gain and muscle atrophy, while making fatigue even more pronounced. This can also affect sexual ability and libido, diminishing a man's ability to engage in fruitful, productive sexual activity.
Andropause and Hypogonadism can also lead to Adrenal Fatigue, as the reduced natural production of Testosterone can increase the body's Adrenal System activity due to physiological stress and Hormone Imbalance, which can inhibit the normal and healthy function of the body. For men with Age-Related Low-T, Testosterone Replacement with Creams, Patches, and Injections can help patients restore normal Sex Hormone and Adrenal Balance.
THE FACTS ABOUT ACROMEGALY
Written by , Article reviewed and edited by Dr. Fine M.D.
Published on 21 June 2014
The Facts About Acromegaly
Acromegaly is a medical condition which is caused by the excessive release of Human Growth Hormone by the pituitary, or by a tumor. The pituitary gland is a very small gland that rests just behind the eyes underneath the brain. The pituitary gland is often referred to as the Master Gland, because of the various functions that the pituitary gland controls, including reproductive function, metabolism, and growth.
What Causes Acromegaly?
The vast majority of patients with Acromegaly experience the condition as a result of a benign tumor attached to the pituitary gland, which imitates the activity of the Somatotrophs which are responsible for the release of Natural Growth Hormone. Excess HGH production over the course of a long period of time causes the body to grow abnormally. It causes the bones and cartilage in the feet, hands, and face to grow abnormally long and thick. Pituitary tumors that cause acromegaly can also lead to migraines because of the increased pressure in the brain, or pressure on the optic nerve.
How Do Hormones Contribute to Acromegaly?
Acromegaly effects the production and activity of three particular hormones that are very important, and all related to the somatotrophs. These are the hormones which are primarily affected by acromegaly:
Human Growth Hormone - Normally, the human body produces HGH throughout the day, in short bursts known as pulses. The hormone is primarily released during deep sleep and during intense physical activity. When the body produces too much HGH, it impacts the growth of organs and systems all throughout the body, and can impact physical appearance.
Insulin-like Growth Factor-One - The release of this hormone is directly influenced by the release of Human Growth Hormone. HGH circulates through the body, and much of it is processed by the liver into IGF-1. IGF-1 remains active more constantly than Human Growth Hormone, and many symptoms of Acromegaly are caused by a simultaneous rise in these two hormones.
Somatostatins - These hormones play an important role in Growth Hormone and IGF-1 regulation. Under normal circumstances, the human body recognizes the influx of HGH and IGF-1 and the brain releases somatostatins in response to mitigate the release of HGH by the pituitary. Somatostatin Therapy plays an important role in the treatment of Acromegaly.
What are the Symptoms of Acromegaly?
Acromegaly is a complex disorder which affects both health and appearance. Many people don't realize that they are suffering from Acromegaly for many years, because the effects onset slowly, and can often be difficult to notice until the symptoms are already problematic. Often, acromegaly symptoms are written off simply as aging by the patient, and there are many conditions which can imitate some of the symptoms of the condition.
Acromegaly often doesn't become clearly noticeable for many years. It is important to understand that although there are many signs and symptoms, most patients only experience a small number of symptoms. Below are the symptoms that are associated with Acromegaly:
Vision Changes due to Tumor Growth
Increased Size of Internal Organs
Increased size of Feet, Hands, and Jaw
Joint Swelling and Pain
Acne, Increased Oil Production, Thicker Skin, and other Skin Issues
Carpal Tunnel Syndrome
How is Acromegaly Diagnosed?
There are a number of tests that can effectively diagnose and keep track of Acromegaly. The most effective blood test for Acromegaly is Growth Hormone Analysis. Normally, HGH Levels spike and remain in the blood stream for only a brief period of time, but in the case of Acromegaly, Growth Hormone Levels remain excessively high, or reach abnormally high spikes..
Natural HGH Secretions are dependent upon a number of different variables, including when the test is taken, age, and genetics, as well as the last time that you ate. The following are the main means by which Growth Hormone Levels are Tested:
Oral Glucose Tolerance Test - The easiest way to analyze Growth Hormone Levels through a single test is for the patient to fast for a single night and provide blood after drinking a specialized solution of glucose concentrate.
IGF-1 Testing - One can also test for Acromegaly by testing IGF-1, which is released directly as a response to Growth Hormone Secretion. IGF-1 is a byproduct of Acromegaly, and it is exceedingly rare that IGF-1 Levels do not increase to abnormally high levels as a result of Acromegaly. IGF-1 Levels can also be easily tested, because they don't spike like HGH Levels.
Acromegaly Imaging Tests for Tumor Identification
Once the case for Acromegaly has been established, the physician will generally recommend imaging scans in order to identify the tumor. This can be completed using a CT Scan or an MRI. These tests provide a high-resolution image of the brain which can be monitored for tumors or other abnormalities. These Imaging Scans are outpatient procedures that do not require any patient preparation.
Health Tests Performed After Acromegaly Diagnosis
After Acromegaly has been diagnosed via HGH/IGF-1 Levels and a visual confirmation on the tumor, there are other tests that will be necessary to assess the health of the patient. Patients will usually undergo vision testing, chest X-Ray, and ECG to monitor the extent to which Acromegaly has affected the health. None of these tests require a stay at a hospital, and none of these tests even necessarily require a trip to the hospital, though they may be performed at one.
The technicians and specialists that perform these tests will forward the results directly to your primary care physician, who will explain the results in detail and use all of the information available to inform you of your current condition and what steps can be taken to improve your health.
Why Is It Important to Control and Treat Acromegaly
Until the tumor is surgically or medically removed, the condition is chronic, but proper treatment can cancel out the health modulating effects of the tumor. Through proper treatment, you can improve your health significantly and significantly reduce the risks associated with the condition.
Most patients begin treatment almost immediately after they have received diagnosis, and your healthcare provider can take steps to control the various factors at play with regard to Acromegaly, including controlling IGF-1 Levels, HGH Levels, treating the symptoms of the disorder, and treating the tumor itself.
Medical Conditions Associated with Acromegaly
Part of effectively treating Acromegaly is being aware of the increased risk of a number of different disorders and treating them accordingly. These conditions include:
Take Control of Your Acromegaly Treatment to Maximize Health Outcomes
It's vitally important to maintain awareness of your Growth Hormone and Insulin-Like Growth Factor-One Levels in order to effectively treat your condition. Your physician will provide you with somatostatins and other medical treatments designed to treat your hyperpituitarism as well as the medical conditions related to the disorder.
Every day that you go untreated, your health becomes that much more at risk. If you get treatment quickly enough, you can even reverse or at least mitigate some of the symptoms, including Hypertension, Sleep Apnea, Fatigue, Joint Pain, Sweating, Cartilage Swelling, and Headache.
Acromegaly Treatment Options
The most effective way to treat Acromegaly is by taking steps to get rid of the tumor. There are also treatments that can reduce the activity of the tumor until you can get access to treatment that will eliminate it.
Surgery for Acromegaly - The most direct way to treat a Pituitary Somatotroph Tumor is through surgery. Because the pituitary is located beneath the brain, it is often possible to remove the tumor with minimal risk, and in doing so, return IGF-1 and Growth Hormone Levels to normal, as well as eliminate Intracranial Hypertension.
This can be achieved through a method known as transsphenoidal surgery. In this procedure, the surgeon enters the brain cavity through the upper lip or through the nose and removes the tumor without having to open the skull.
Acromegaly and Human Growth Hormone
Acromegaly is a Pituitary Condition
Even though HGH Abuse can lead to symptoms that are normally associated with Acromegaly, it is important to point out that Acromegaly is a specific medical disorder which is caused by a tumor on the pituitary gland, and although long term abuse of Human Growth Hormone can lead to symptoms similar to Acromegaly, the two conditions are unique to one another.
Can HGH Injection Therapy lead to Acromegaly?
No. The goal of Human Growth Hormone Injections is to restore optimal, youthful HGH and IGF-1 Levels in the blood stream, not to introduce more of the hormones than the body is capable of handling in a healthy way. Acromegaly-like symptoms are the result of a long-term flood of Human Growth Hormone, and cannot be triggered by Restorative Doses of HGH.
HGH Abuse and Overdose Does Not Lead to Acromegaly Symptoms for a Long Period of Time
Also, like the condition of Acromegaly itself, it can take years of excess HGH and IGF-1 Levels before it becomes physically apparent that the patient is suffering from such a condition, whether it is from the disease of Acromegaly or the decision to abuse Bio-Identical HGH.
If a patient does begin to show Acromegaly-like symptoms, such as joint stiffness, carpal tunnel syndrome, or increased soft tissue production, there is still time to mitigate or prevent long-term damage to physiological health by suspending Injectable Growth Hormone Abuse.
Famous People with Acromegaly
Today, Acromegaly is recognized more quickly than it was in the past, and treated more promptly, but over the last fifty years there have been a number of celebrities that are known for having Acomegaly, the most famous of which is Andre the Giant. Andre the Giant was 7 foot 4 inches and weighed as much as 520 pounds. He first reached celebrity status as a star of the World Wrestling Federation, and later had a notable acting career, starring in films such as The Princess Bride and Conan the Destroyer.
Although he was largely seen as a beloved character, he dealt with an immense amount of pain from his condition which led him to alcoholism. In spite of his propensity for drinking and his wrestling persona, he was widely regarded as an incredibly kind and gentle person.
Other Celebrities with Acromegaly:
WWE star Big Show, also known as Paul Randall Wight, Junior
UFC Fighter Antonio Silva
Richard Kiel, most famously known for his role as Jaws for the James Bond Franchise
Carel Struycken, who starred as Lurch in the Adams Family films
THE FACTS ABOUT PSORIASIS: SYMPTOMS AND CAUSES
Written by , Article reviewed and edited by Dr. Fine M.D.
Published on 21 June 2014
The Facts About Psoriasis
What Is Psoriasis?
Psoriasis is a medical condition that impacts around three percent of people in the United States. There are over five million men and women with psoriasis across the nation. Psoriasis is characterized by inflammation and scaling of the skin, and is mainly seen in adult patients, though psoriasis can also become an issue during childhood and adolescence. There is no gender divide with this condition, as both women and men are equally likely to experience the condition.
How Does Psoriasis Impact Skin Health?
The mechanism which causes scaling and inflammation is that new skin cells, which normally mature beneath the skin and rise to the surface, move to the surface before they have sufficiently developed. It normally takes a newborn skin cell around thirty days to reach the top layer of the skin, but in the case of Psoriasis, this process of turnover can take place in just a matter of days.
What Are the Symptoms of Psoriasis?
In the most common form of the condition, Psoriasis leads to high levels of inflammation, and the skin becomes red and topped with scales. The areas where scaling develops are called plaques, and they can lead to soreness and severe itching. Common areas where Psoriasis appears on the body are the soles of the feet, palms, face, lower back, scalp, knees, and elbows, although these patches can appear anywhere on the body.
Other areas where Psoriasis can appear are inside the mouth, on the genitals, and underneath the toenails and fingernails. If Psoriasis occurs on the joints, it can lead the inflamed area to become cracked and this can lead to bleeding. The psoriasis can also inflame the joints, which leads to arthritis symptoms. If this occurs, it is referred to as Psoriatic Arthritis.
How Can Psoriasis Negatively Impact Quality of Life?
People that have Psoriasis can experience life-altering issues resulting from the pain and itching associated with Psoriasis. Also, Psoriasis can limit movement in some cases, leading to limited disability.
Some patients experience severe pain and itching, which prevents them from living and appreciating their day to day life, causing sleep to be restless, making bathing a painful chore, and even making walking difficult. Patients that have Psoriasis Plaques on the feet and hands can have issues with any activity that involves those body parts, and they may not be able to participate in some sports or even have jobs in some careers. This can even inhibit their ability to care for their loved ones.
In order to mitigate the symptoms of Psoriasis, it can require frequent trips to the doctor, and the cost to treat the medical disorder is very high, as a result of the chronic nature of the condition. Psoriasis also impacts self-perception, because they are embarrassed about the way they look as a result of their condition. This can lead them to become withdrawn, or make it harder for them to enter romantic relationships. These issues can lead to social isolation, depression, and other psychological issues related to their poor self-image.
What Causes Psoriasis?
Psoriasis is a medical condition that results from an overactive immune system, and it is related to the body's production of T-Cells. T-Cells are powerful immune cells which fight disease and infection. When a person has Psoriasis, the body activates T-Cells for no reason and this causes a cascade of immune response which both causes immature skin cells to rise prematurely while also causing high levels of inflammation.
There is a genetic component to Psoriasis, and scientists have been able to link particular genes to the condition, based upon their study of certain family lines which are heavily impacted by the condition. Not all patients with Psoriasis have a family history, however.
What Causes Psoriasis Skin Flare-Ups?
Most people with psoriasis experience periods where their skin health becomes more problematic. These periods are known as flares. Psoriasis will temporarily become much worse, before recovering somewhat. There are a number of issues that can cause these flares to occur, including weather changes that lead to drier skin, stress, and infection.
There are also some medications that can exacerbate Psoriasis, including lithium and blood pressure medications known as Beta-Blockers. Finally, Psoriasis is more likely to flare up in areas of the skin that have experienced damage or irritation from issues such as infection, sunburn, scratches and lesions.
How Do Doctors Diagnose Psoriasis
Sometimes, Psoriasis can be problematic to diagnose, because it shares symptoms with a number of other skin conditions, such as Sebhoerric Dermatitis. The best way to clinically diagnose Psoriasis is by taking a small patch of the inflamed skin and looking at it through a microscope.
What Are the Types of Psoriasis?
There a number of kinds of Psoriasis. Below is a partial list:
Plaque Psoriasis - Characterized by inflamed, red skin covered in shiny scales.
Guttate Psoriasis - Characterized by small, round areas of inflamed skin on the scalp, limbs, and trunk. This form of the disease is commonly a reaction to strep throat or other infections of the upper respiratory system.
Pustular Psoriasis - Characterized by the formation of blisters which are not the result of infection. These blisters are filled with puss, and can be caused by stress, infections, medicines, and contact with particular chemicals.
Inverse Psoriasis - Characterized by inflamed areas along skin folds, such as the armpits, beneath the breasts, or around the genitals. Sweating and friction can exacerbate this form of Psoriasis.
Erythrodermic Psoriasis - Rapid and widespread appearance of Psoriasis that is commonly caused by corticosteroid medicines or significant sunburn. This form of Psoriasis can also occur as an extension of other forms of Psoriasis which are not effectively controlled. This is the most severe form of the condition, and requires an immediate visit to a medical professional.
What is Psoriatic Arthritis?
Psoriatic Arthritis is a medical condition that is related to and caused by Psoriasis, itself. In this case, Psoriasis penetrates into the skin and causes lesions and inflammation of the joints. Patients can experience both forms of Psoriasis simultaneously, or either alone at any particular time.
How Can Psoriasis Be Effectively Treated?
There are a number of methods that physicians use to mitigate the symptoms of Psoriasis, dependent upon the specific characteristics of the disease, including the locations of inflammation, the form of psoriasis, the surface area of inflammation, the severity of the psoriasis, and the way that the patient has responded to previous treatment.
The following are some common means by which Psoriasis can be treated:
Like any medication, the treatments listed above can lead to side-effects, some minor, some more significant. Always talk to your physician and pharmacist about potential side-effects so you can be armed with the knowledge to recognize them.
There are some issues that make Psoriasis hard to treat. For one, the body can develop a resistance to certain forms of treatment, limiting their effectiveness over time. This is especially true of corticosteroids delivered topically.
Second, every patient responds differently to treatment, and the same medication or therapy may be highly effective for one patient while producing no benefit in a second patient. As a result of this, physicians often switch from therapy to therapy until they find one that works effectively with few or no side effects.
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