“The effects of six months of human growth hormone on
lean body mass and adipose tissue reversed the equivalent of changes incurred during 10-20 years of aging.” "The overall deterioration of the body that comes with growing old is not inevitable... We now realize that some aspects of it can be
prevented or reversed."

- Dr. Daniel Rudman, MD - New England Journal of Medicine

Some Goals of HGH Therapy

1. Reverse the effects of aging

2. Reverse muscle wasting

3. Reduction in Weight and body fat after six months, without dieting

4. Increase in lean muscle after six months, without exercise

5. Increase energy level, endurance and exercise capacity

6. Increase cardiac output

7. Reduce stress and enhances immune system

8. Accelerate wound healing and skin regeneration

9. Improve memory retention and cognitive functions

10. Increase recovery from injury

11. Improve vision

12. Achieve a younger, tighter, thicker skin

13. Improve kidney function

14. Reverse osteoporosis Improve sleep

Note: HGH cannot be prescribed for anti-aging, athletic performance enhancement, or body building.

What are hormones?

Hormone, secretory substance carried from one gland or organ of the body via the bloodstream to more or less specific tissues, where it exerts some influence upon the metabolism of the target tissue. Normally, various hormones are produced and secreted by the endocrine glands (see endocrine system), including the pituitary, thyroid, parathyroids, adrenals, ovaries, testes, pancreatic islets, certain portions of the gastrointestinal tract, and the placenta, among the mammalian species. As lack of any one of them may cause serious disorders, many hormones are now produced synthetically and used in treatment where a deficiency exists. The hormones of the anterior pituitary include thyrotropin, adrenocorticotropic hormone, the gonadotropic hormones, and growth hormone; the posterior pituitary secretes antidiuretic hormone, prolactin, and oxytocin. The thyroids secrete thyroxine and calcitonin, and the parathyroids secrete parathyroid hormone. The adrenal medulla secretes epinephrine and norepinephrine while the cortex of the same gland releases aldosterone, corticosterone, cortisol, and cortisone.

The ovaries primarily secrete estrogen and progesterone and the testes testosterone. The adrenal cortex, ovaries, and testes in fact produce at least small amounts of all of the steroid hormones. The islets of Langerhans in the pancreas secrete insulin, glucagon, and somatostatin. The kidneys also produce erythropoietin, which produces erythrocytes (red blood cells). The passage of chyme (see digestive system) from the stomach to the duodenum causes the latter to release secretin, which stimulates the flow of pancreatic juice. The duodenum can also be stimulated by the presence of fats in the chyme to secrete cholecystokinin, a hormone that stimulates the gall bladder to contract and release bile. There is evidence that the upper intestine secretes pancreatozymin, which enhances the amount of digestive enzymes in the pancreatic juice. In addition, the pyloric region of the stomach secretes gastrin, a hormone that increases the secretion of hydrochloric acid into the stomach. The placenta has been shown to secrete progesterone and chorionic gonadotropin. There is evidence that it even contains a substance similar to growth hormone. Insects have a unique hormonal system that includes ecdysone, a steroid that influences molting and metamorphosis, and juvenile hormone, needed for early development. Plants, too, have a hormonal system, which includes the auxins, the gibberellins, the cytokinins, and substances associated with the formation of flowers, tubers, bulbs, and buds. Ethylene is said to function as a hormone in plants, acting to hasten the ripening of fruits.


Growth Hormone levels?

The hormone most often said to affect aging and promote anti-aging is growth hormone. Growth hormone plays a pivotal but intermediate role in the anti- aging process. The lack of this hormone doesn't bring about aging, but rather, the hormone lies in the middle of the aging cascade. Giving supplemental growth hormone to the aging body will restore some lost muscle mass and redistribute fat within the body, however it will not affect many other common aging changes, such as hair loss.

Researchers had long noticed that growth hormone hits its peak when the body goes through the rapid growth phase during adolescence. Hence the hormone?s name. Most growth hormone secretion takes place in brief bursts called pulses that occur during the early hours of the deepest sleep. Indeed the old adage that you grow while you sleep appears to have a basis in fact.

Interestingly, growth hormone hangs around in the bloodstream for a very few minutes. However, this is long enough to stimulate its uptake into the liver, where it is converted into growth factors. Regulation of Growth Hormone is complex and comes under the control of many factors that regulate its release and function. Growth hormone declines with age in every animal species that has been tested to date. In humans, the amount of growth hormone after the age of twenty-one to thirty-one falls about 14 percent per decade, so that the total twenty-four-hour growth hormone production rate is reduced by half by the age of sixty.

Effects of Human Growth Hormone decline

The decline in human growth hormone is directly tied to the bulging, wrinkling, saggy, flabby, draggy creatures that we all sooner or later start to see in the mirror. Those of us with naturally lower amounts of hormone age much faster and more visibly that those of us who by reason of genes or high exercise level maintain a higher level of secretion for a longer period of time. The loss of the hormone with age is similar to that seen with menopause. And it has been given a similar name, the somatopause.

Health Tips About Using HGH

* BEGIN WITH SMALL DOSES Like many hormones, HGH is very potent. More is not better. If you are just starting HGH replacement therapy, begin with small doses in the range of 0.1 to 0.3 mg per day. Remember that the goal of HGH replacement therapy is to restore your HGH production level.

* WATCH FOR ADVERSE SIDE EFFECTS: Almost all adverse effects of HGH (water retention, sore muscles, numbness in the hands) are related to doses that are too high. If you are retaining water, ask your physician about lowering your dosage. Prolonged overproduction of HGH can cause serious side effects. This can occur in adults who have a hormonal disorder call acromegaly. The disorder is characterized by abnormal growth of the hands and feet. Soft tissue swelling of the hands and feet is often an early symptom, with patients noticing a change in ring or shoe size. If you notice any signs associated with acromegaly, consult your physician (preferably an endocrinologist).

* EXERCISE: If you don't have an exercise program, start one. It doesn't have to be at a gym. Find a program that fits your life---walking, swimming, sports---anything that provides a reasonable workout several times a week. Studies have shown that HGH replacement therapy is more effective for people who exercise regularly.

* MULTIPLE VITAMINS: Continue with a good multiple vitamin program that includes Vitamin C and Vitamin E.

* SLEEP: Sleep is important to good health and it appears that several anti-aging hormones are produced at higher levels during sleep than during waking hours.

* WATCH YOUR WEIGHT: HGH replacement therapy is not a diet program. Well it does tend to build muscle and reduce fat, many users find that they have an increased appetite.

* SKIN AND SUN: When you are in the Sun, use sun protection. Use a good skin lotion morning and night. Consider using an "age-defying" lotion like that produced by Ponds or Oil of Olay.

* DON'T SMOKE: If you have started HGH replacement therapy to look better, then don't smoke. Among other things, smoking makes your skin look older.

* WATER: Drink plenty of water---every day - minimum 8 glasses!

Sermorelin

Sermorelin is a biological active analog of growth hormone releasing hormone (GHRH) that is produced by the human brain to stimulate production and release of growth hormone by the pituitary gland.

Sermorelin stimulates production of the body's own HGH. It is a truncated analog of growth hormone releasing factor (GRF 1-44) that is naturally produced by the brain to stimulate pituitary production and secretion of HGH.

During youth, ample amounts of GHRH are produced so that the pituitary is able to provide the body with sufficient growth hormone to sustain health, vitality and otherwise normal aspects of form and function. GHRH declines with age causing reduced production and secretion of pituitary HGH and thereby increasing the sequelae of growth hormone insufficiency.

Unlike HGH, Sermorelin affects a more primary source of failure in the GH neuroendocrine axis, has more physiological activity, has a better safety profile, and its use for adult hormone deficiency is not restricted.
Sermorelin benefits:

* Increases natural production of Growth Hormone
* Improves Physical Performance
* Improves Immune Function
* Increases IGF-1
* Improves sleep quality
* Decrease body fat
* increase lean muscle mass

While Sermorelin produces the same effects on body composition and provides the other benefits of HGH, it also has some additional and important benefits.

The effects of Sermorelin are regulated at the level of the pituitary gland by negative feedback and by release of somatostatin so that safety concerns associated the HGH overdosing are minimized or completely avoided.

Tissue exposure to HGH released by the pituitary under the influence of Sermorelin is episodic not ?square wave?, and therfore, prevents tachphylaxis by mimicking normal physiology. By stimulating the pituitary it preserves more of the growth hormone neuroendocrine axis that is the first to fail during aging.