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What is Sermorelin?
Sermorelin is a synthetic drug which is derived from GH-RH, which is also known
as Growth Hormone-Releasing Hormone. GH-RH is the hormone responsible
for the production of Human Growth Hormone, commonly referred to as
HGH. GH-RH is secreted by the hypothalamus and functions as a
chemical messenger which sends the signal to the pituitary to secrete
more Human Growth Hormone to be delivered throughout the body.
Sermorelin is not naturally produced by the human body, but it is functionally
identical to Growth-Hormone Releasing Hormone produced by the human
body. Sermorelin contains the same initial 44 proteins that are
present in GH-RH, and scientists and researchers have discovered that
this truncated version of Growth Hormone-Releasing Hormone is the
shortest known derivative that produces an identical effect upon the
body as GH-RH, which is to enhance pituitary secretion of HGH.
and Human Development
In our preteen and early teenage years, Human Growth Hormone is
primarily responsible for the increase in growth rate associated with
puberty. Children that suffer from a deficiency in Growth
Hormone-Releasing Hormone do not produce sufficient levels of Human
Growth Hormone and therefore do not grow at the same rate as their
peers. Human beings complete the process of normal growth and reach
their final adult height after the epiphyseal plates of their long
bones close at the end of puberty.
After this point, the role of Human Growth Hormone changes, yet the role of
GH-RH remains the same. After puberty, the body needs to produce
sufficient levels of Growth Hormone-Releasing Hormone that allow the
body to secrete the HGH that it needs to sustain itself at peak
condition, allowing us to enjoy maximum vitality and health. GH-RH
allows the body to function optimally as it was meant to function.
Age, GH-RH Levels Decline
Unfortunately, production of Growth Hormone-Releasing Hormone by the pituitary drops
as we age, and this reduction in endogenous production of GH-RH is
directly correlated with reduced release of Human Growth
Hormone, which inevitably leads to a rapidly sped up aging process.
At age twenty, the human body produces an optimal level of adult
Human Growth Hormone – around five hundred micrograms each day.
By the time we reach our late twenties to early thirties, the levels
of endogenous Human Growth Hormone that we produce decreases at a
seemingly marginal rate of one to two percent each year. Over time,
however, this constant decline accumulates, leaving our bodies
grossly deficient in Human Growth Hormone. By the time we reach the
age of eighty, the human body only secretes around sixty micrograms
of Human Growth Hormone daily – often even less! In otherwise
healthy adults, an HGH level of around two hundred micrograms is
The effects of Human Growth Hormone Deficiency begin to become more
pronounced as we enter our late thirties and early forties. At this
point, our deficiency in Human Growth Hormone begins to greatly
under-perform and our bodies start to age more rapidly. Rapid aging
is not inevitable, however. And Sermorelin Therapy is a fantastic
means by which to alleviate the effects of age in a way that
allows us to grow old in a healthy way that does not take from us our
HGH Therapy vs. Sermorelin Therapy
Human Growth Hormone Replacement Therapy is effective at treating Human
Growth Hormone Deficiency, but it may not be the most efficient way
to restore optimal hormone production. It may only be covering up an
HGH Hormone Replacement Therapy simply replaces endogenous Human Growth
Hormone with HGH from an outside source. Sermorelin works by
increasing the level of HGH naturally secreted by the body, which
leads to more natural release of the hormone throughout the
body when and where it is needed. Sermorelin treats underlying
neuroendocrine failure which leads a large number of patients who
suffer from Human Growth Hormone Deficiency while having a perfectly
healthy pituitary function.
For these patients, Sermorelin Hormone Replacement Therapy produces more
natural physiological function while also being safer and having a
significantly lower risk for unwanted side-effects than simply
treating the symptoms of Human Growth Hormone Deficiency rather than
the root cause. In addition to this, Sermorelin Hormone Replacement
Therapy is not restricted in the same manner as HGH Hormone
Replacement Therapy for use in patients that suffer from HGH
Benefits of Sermorelin:
Below are just a few of the Benefits of Sermorelin Therapy:
Sermorelin enhances the Pituitary Gland's natural ability to produce endogenous
Human Growth Hormone, leading to a more natural Hormone Profile<
Sermorelin optimizes the human body, increasing physical and mental performance
Sermorelin strengthens immune health
Sermorelin boosts the liver's production of Insulin-Like Growth Factor One
Sermorelin helps patients sleep longer, deeper, and better
Restoring Endocrine Function with Sermorelin
As a result of generations of Anti-Aging and longevity science, we
realize today that Hormonal Balance is the key to preserving the
optimal function of the many organ systems that make up the human
body. When hormones are not released in sufficient amounts, or
when certain hormones are produced in excess, the body can suffer
greatly as a result. This is more apparent regarding HGH and its
correlated secretagogue, Growth Hormone-Releasing Hormone, than with
any other hormones produced by the body. A myriad of issues that are
correlated with the process of aging are intricately
connected to insufficient levels of GH-RH and HGH in the brain and in
the blood stream. Though there are a multitude of
reasons why the body produces less Human Growth Hormone as we age,
among the most prominent and easily resolved issues is GH-RH
Deficiency, which can easily and safely be restored with Sermorelin
What Makes Sermorelin Preferable to HGH Hormone Replacement Therapy?
The effects of HGH injections are not well-regulated by the body. If a
person administers too much Human Growth Hormone, the body has no way
of negating the effects of the flood of HGH entering the body. The
pituitary gland may depress over time and release less endogenous HGH
to compensate, but the body will still over-react to excess levels of
HGH that occur as a result of overdose or abuse. This
reduced level of endogenous HGH production is actually a
bad thing, because once an individual suspends HGH
injections, the body will not be able to produce the same levels of
Human Growth Hormone as it once did until it slowly increases its
natural production again over a significant period of time.
HGH and Negative Feedback
On the other hand, the effects of excess synthetic GH-RH are regulated
in two ways by the body. One way is by means of negative feedback.
Via negative feedback, the pituitary gland sends a message to the
hypothalamus telling it that it no longer needs to produce more Human
Growth Hormone. The second manner by which Human Growth Hormone
production is regulated when using Sermorelin is by somatostatins.
Somatostatin HGH Inhibitor
Somatostatins are hormones which prevent the pituitary from taking up excess levels
of Growth-Hormone Releasing hormone, thereby preventing the Pituitary
Gland from producing excess levels of HGH. By means of these binary
inhibitory factors, the risks associated with Human Growth Hormone
are minimized, and when Sermorelin is used correctly with a
physician's prescription, the side-effects of HGH overdose will
likely be completely eliminated.
Sermorelin is Safer and More Natural than HGH Hormone Replacement Therapy
Patients who use HGH Hormone Replacement Therapy are at a slightly enhanced
risk of joint disorders such as Arthritis and Carpal Tunnel Syndrome.
Older patients may find this reason enough to forgo HGH Therapy for
Sermorelin Therapy. In addition to this, patients who undergo Human
Growth Hormone Replacement Therapy sometimes suffer from temporary
blood sugar fluctuations as a result of surging or quickly
dissipating IGF-1 levels. These effects are not present when using
Another way that Sermorelin Therapy is superior to HGH Hormone Replacement
Therapy in many patients is that Sermorelin encourages a more natural
production of Human Growth Hormone by the body. Sermorelin Therapy
leads to episodic production of Human Growth Hormone, which
is the manner by which the human body naturally secretes Human Growth
Hormone. HGH is secreted by the pituitary gland in pulses which
quickly dissipate throughout the body, where it is eventually
converted into IGF-1 by the liver.
One patient group that may prefer Human Growth Hormone Replacement
Therapy are patients that are interested in faster results at the
expense of taking a bit of risk. Sermorelin Therapy takes a bit
longer to produce physiological changes, but there is only a minimal
chance of side effects as a result of therapy.
When undergoing Human Growth Hormone HRT, HGH is released into the body
from the injection in a square wave. This means that the body is
initially exposed to a high level of HGH which slowly dissipates
between administrations, rather than in the natural spurts of
production that the body is accustomed to. By
preserving normal physiological production of Human Growth
Hormone, a phenomenon known as tachphylaxis is
prevented. Tachphylaxis is the phenomenon by which the body
responds to an excess or constant level of a particular medicine or
hormone by developing a sudden and increased resistance to that
medicine or hormone, reducing its effect on the body. Some physicians
who recommend Human Growth Hormone Therapy will accompany it with a
certain level of Sermorelin Therapy as a means to prevent the
pituitary gland from reducing its activity in the wake of increased
exogenous Human Growth Hormone.
It is important to supplement the natural hormone production of the body
in as natural of a manner as possible so that we may preserve the
natural neuroendocrine axis that HGH is an important component of. As
we age this axis becomes more and more fragile and prone to
degradation and insufficiency.
Frequently Asked Questions Regarding Sermorelin
What is Sermorelin?
Sermorelin is a synthetic hormone which is functionally identical to
Growth-Hormone Releasing Hormone (GH-RH), otherwise known as Growth
Hormone Releasing Factor (GRF). In many scientific papers, Sermorelin
is referred to as GRF 1-29 NH2.
Is Sermorelin Chemically Identical to GH-RH?
No. Sermorelin only consists of the initial twenty-nine amino acids that
make up GH-RH However, even though Sermorelin differs biologically
from GH-RH, the human body treats the two substances the exact same
way in the body. GH-RH features an amino acid chain which
is 44 peptides in length.
What type of cells produce GH-RH?
GH-RH is manufactured by the neurosecretatory cells in the human
brain. Neurosecretatory cells are specific neurons which
take neurological signals from other parts of the brain and convert
them into chemical messengers to distribute to other parts of the
brain or throughout the body.
Who discovered GH-RH?
GH-RH was initially characterized by A. Shalley and
R. Guilleman during the 1970s thanks largely to the efforts
of their student W. Wehrenberg. Wehrenberg was interested in
determining which portion of the Human Growth Hormone molecule was
necessary to stimulate the pituitary gland. After a period of trial
and error in which he deleted individual acids from the peptide
sequence, he eventually reached a tipping point after which, the
hormone no longer produced stimulative action. He discovered that,
after deleting the last 16 amino acids from the peptide chain, the
first twenty nine amino acids were the only necessary
peptides needed to stimulate the endogenous manufacture and secretion
of Human Growth Hormone. This is the ultimate reason why Sermorelin's
chemical notation is GRH 1-29 NH 2. The final portion of the
notation, NH2, represents the final amino acid of GH-RH.
Are Human Growth Hormone and Sermorelin Biologically Identical?
Sermorelin and Human Growth Hormone are unique substances that stimulate
different hormonal functions within the human body. Sermorelin
functions as a precursor for the production of HGH. A Human Growth
Hormone Precursor is also known as an HGH Secretagogue. This is a
simplified way of saying that Sermorelin activates the pituitary
gland, thereby stimulating the production and secretion of HGH
throughout the body. Sermorelin is significantly smaller than Human
Growth hormone. HGH is the largest hormone produced by the human
body, at a length in at 191 amino acids, whereas Sermorelin is tiny
in comparison, consisting of only 29 of those acids.
What are OTC HGH Secretagogues? Are they the same as Sermorelin?
No, Over the counter secretagogues, also known as Human Growth Hormone
Releasers, are something completely different than Sermorelin.
Commonly advertised HGH Releasers consist of amino acids such as
L-dopa, glycine, L-ornithine, L-glutamine, and L-arginine. Herbal
supplements such as Tribulus terrestris and
Macuna pruriens are also often advertised as HGH Releasers,
as well as the substance ornithine alpha-ketoglutarate. It is true
that with a significantly high dosage of a concoction of any of these
HGH releasers can sometimes produce a pituitary response in
which Human Growth Hormone is secreted, the effect that it produces
is not specific. This means that the effect that HGH Releasers have
on the brain will affect the entire brain and not
specifically one specific region. Sometimes this results in the
secretion of Human Growth Hormone. Exercise also has a non-specific
effect on the body, stimulating the entire brain. The effect of these
Human Growth Hormone Releasers is unreliable and sporadic, however,
because there is no simple and specific process by which any of the
ingredients directly stimulate the pituitary.
Are OTC HGH Secretagogues and Hormone Releasers Safe?
At best they will be inert, and at worst they can be highly damaging to
the body. Because HGH Releasers require high doses to show any level
of effectiveness, they can be very bad for the liver. After the
ingredients of the HGH Releaser are digested by the stomach they are
delivered to the liver which attempts to break them down. The liver
is not optimized to break down large amounts of these amino acids and
can deteriorate over time as a result. The kidneys also suffer in a
In short: yes. Since Sermorelin is injected rather than digested, it
bypasses the liver and kidneys and is delivered directly to the brain
where it is needed. Sermorelin bonds to very specific kinds of
receptors located on the somatotrophs of the pituitary gland. These
somatotrophs are very efficient at absorbing Sermorelin as it is
needed. In addition to this, Sermorelin injections feature
significantly fewer amino acids. The body responds actively to a very
small amount of Sermorelin; therefore, there is no reason to flood
the body and brain with excess amino acids which will only tax the
liver and the kidney. When used appropriately, Sermorelin is
incredibly safe and produces very limited side effects in a minority
Why Should I Consider Sermorelin When HGH Therapy Has Been Proven
There are several reasons to consider Sermorelin over Human Growth Hormone.
Yes, it is true that Sermorelin and Human Growth Hormone Replacement
Therapy produce the same positive effects on the human body, but
there are advantages to Sermorelin Therapy which make it a much
better option for a significant number of patients. Sermorelin
largely eliminates the risk of Human Growth Hormone overdose, because
the body regulates GH-RH and Sermorelin in a way that it is not
capable of regulating Human Growth Hormone. If too much Sermorelin is
present in the body, then the pituitary gland sends messages to the
hypothalamus telling it to drop endogenous production of Growth
Hormone-Releasing Hormone. In addition to this, the Hypothalamus
produces Somatostatins which reduce the amount of Sermorelin or GH-RH
that the Pituitary Gland can absorb.
In addition to this, Sermorelin produces a natural ebb and flow of Human
Growth Hormone Production which is just not possible when using Human
Growth Hormone Injections. HGH Injections simply splash the blood
stream with Human Growth Hormone which slowly recedes throughout
the day. Also, by stimulating the pituitary gland in a natural way,
Sermorelin stimulates the pathway of blood vessels which connect the
hypothalamus and the front portion of the pituitary gland. This
pathway is known as the hypophyseal portal system. In addition to all
of this, off-label usage of Sermorelin is not a violation of American
Federal law, whereas there are strict limitations which prevent the
Off-Label use of Human Growth Hormone Therapy.
Do I Have to Inject Sermorelin?
of today, the only means by which to deliver Sermorelin is by means
of subcutaneous injection. There is an active theory that it may be
possible to deliver Sermorelin via a nasal spray, but this is still
hypothetical and there is no proof that such a method is viable.
There is theoretical evidence that it may be possible, because,
although it has been proven that Human Growth Hormone cannot be
delivered via nasal spray, it may be possible for Sermorelin to
navigate the nasal mucousa barrier because Sermorelin is a
significantly smaller molecule than HGH. Clinical tests are currently
underway, and the results of these tests should be released
much does Sermorelin Therapy cost, and how does this relate to Human
Growth Hormone HRT?
Therapy is about ten to fifteen percent cheaper per vial than Human
Growth Hormone Replacement Therapy. In addition to this, a vial of
Sermorelin can last as long as thirty days for a patient, whereas a
vial of Human Growth Hormone generally lasts approximately two weeks.
This means that Sermorelin is significantly less expensive than Human
Growth Hormone Replacement Therapy while also producing greater and
safer results for patients who suffer from HGH Deficiency.
does one compare the effective doses of Sermorelin and Human Growth
takes around the same amount of Human Growth Hormone to produce a
sufficient effect as it does when one takes Sermorelin. This is true
in spite of the fact that the two hormones produce their effect in
different areas of the body. Sermorelin stimulates the pituitary
gland, whereas Human Growth Hormone Therapy bypasses the brain
entirely, functioning through its relationship with the liver. The
same amount of both hormones leads to similarly increased levels of
Insulin-Like Growth Factor One. It is important to note, however,
that Sermorelin is measured in micrograms generally, whereas Human
Growth Hormone is prescribed in International Units.
the effects of Human Growth Hormone Therapy diminish after Several
Consecutive Months of Continuous Use. What Causes This, and Does This
Also Occur with Sermorelin Therapy?
is absolutely normal for Human Growth Hormone Replacement Therapy to
lose some of its potency after a half year or more of treatment. This
is not the result of faulty Bio-Identical HGH or a fluke in the
individual chemistry of a patient. The body begins to develop a
resistance to HGH Hormone Replacement Therapy because the body is
inundated with levels of Human Growth hormone that are abnormally
high for periods of several hours daily. It's simply the nature of
Subcutaneous HGH Therapy. In addition to this, the constant release
of Human Growth Hormone in the body leads to a correlated abnormal
increase in Insulin-Like Growth Factor One levels in the body which
leaves organic tissues more inundated with IGF-1 than they are
normally accustomed to. These aspects of Human Growth Hormone
Replacement Therapy cause the tissues of the body to regulate their
intake of IGF-1 in response to the influx of the hormone, reducing
the effectiveness of each IGF-1 molecule.
body is accustomed to occasional pulses of Human Growth Hormone
throughout the day, leading to a natural ebb and flow of HGH and
IGF-1 available to the body. When undergoing Sermorelin Therapy, the
pituitary and hypothalamus are able to control the level of Human
Growth Hormone distributed to the body, optimizing its release to
when it is needed by the body to function optimally. This gives the
organs and tissues of the body time to recover from periods of IGF-1
stimulation. Because of this significantly different way in which
Sermorelin functions in the human body, the effectiveness of
Sermorelin Therapy does not atrophy over time.
Sermorelin Treat Other Disorders Which Are Not Specifically Tied to
the Endocrine System?
appears that this is the case. It is proven in one field in
particular that Sermorelin has beneficial effects: The area of Sleep
Study. There is significant clinical evidence that suggests that
Sermorelin and Growth-Hormone Releasing Hormone can aid patients who
have trouble sleeping by stimulating Stage 4 Deep Non-Rapid Eye
Movement Sleep. Taking Sermorelin injections nightly allows the body
to develop a natural sleeping rhythm that assists the patient in
achieving a longer and more restful sleep. There are likely other
non-endocrine benefits to Sermorelin as well, but this field of study
is relatively new.
is the proper schedule for administering Sermorelin?
is most effective when injected subcutaneously once each day before
going to bed. This is vitally important, because the body
naturally produces more Growth Hormone-Releasing Hormone while we
sleep, so injecting at night helps mimic the body's natural Human
Growth Hormone secretion schedule. It is also recommended not to eat
late meals when undergoing Sermorelin Therapy. Going to sleep with a
stomach that is empty will aid the circadian rhythm and help the body
focus on repair and rejuvenation rather than digestion.
should I do if I happen to miss a Sermorelin dose?
you miss a dose of Sermorelin, don't worry. It's not the end of the
world. Just wait until the next night and take your routine normal
dose of Sermorelin at that point. There is no benefit to doubling up
doses to try to make up for a missed dose, so we advise against it
of Adult Human Growth Hormone Deficiency
are a number of symptoms of the aging process that can be at least
partially the result of HGH Deficiency. The more of these symptoms
that you suffer from at the same time, the more likely your personal
issues are the result of Human Growth Hormone Deficiency:
who suffer from Hormone Deficiency are often overweight for their age
and height. This added weight tends to accumulate around the
midsection. Adipose fat deposits develop on the stomach, hips, and
thighs. These fat deposits are the hardest to get rid of, even with
increased exercise and improved diet.
you suffer from anxiety or depression?
Deficiency can destabilize your mood which can lead to general
dysthymia or even extreme depression. Such deficiency can also lead
to elevated levels of stress which are correlated with high levels of
cortisol. The effects of anxiety and depression are exacerbated by
physical symptoms of Human Growth Hormone Deficiency.
you have high levels of LDL (Bad) Cholesterol or lower levels of HDL
Growth Hormone Deficiency leads to reduced metabolism This reduced
level of metabolism can result in poor cholesterol levels which are a
precursor for life-threatening illnesses such as heart attack,
stroke, and cardiovascular disease.
you find yourself exhausted by midday, or do you find yourself
unable to wake up in the morning?
Deficiency can lead to many issues regarding your ability to keep
your game face on throughout the entire day. HGH Deficiency is
intricately related to sleep disorders which prevent you from getting
the deep and restful sleep you need to be a fully functional human
being. Also, poor metabolism prevents your body from getting the
juice it needs from your dietary habits, leaving you listless and
weary when you should be vibrant and on point. This generalized
fatigue can leave you unable to take advantage of life's great
opportunities and joys.
you experiencing a decreased sex drive or inability to perform in
Growth Hormone Deficiency can have devastating effects in the
bedroom. The pressures of anxiety, depression, and negative
self-image all combine in a way that can genuinely lead to your
disinterest in sex. Reduced endurance can leave you exhausted and
unable to perform at the level you once were able. In addition to
this, issues with obesity and blood pressure can easily hinder your
ability to be physically ready for sex as a man.
you feel that you are not as strong as you once were? Do your muscles
lack the definition they once had?
Deficiency has significant effects on muscle mass. HGH plays a
crucial role in the maintenance of the muscles, and without the
rejuvenating effects of healthy levels of Human Growth Hormone, your
body will inevitably begin to lose its ability to maintain muscle
mass. This reduction in muscle mass will directly lead to a reduction
in overall strength.
you suffer from diminished levels of endurance or physical stamina?
Can you not work out as intensely or as hard as you once did?
Growth Factor One is one of the key means by which the human body
releases energy for physical activity. IGF-1 breaks down stores of
adipose fat, converting that fat into usable energy. HGH levels spike
more often during strenuous cardiovascular activity so that that HGH
can be converted to IGF-1 which will provide much-needed fuel
for exercise. If you suffer from Human Growth Hormone Deficiency,
this energy pipeline is much less efficient and, as a result, the
body is much less equipped for long and vigorous workouts.
you been diagnosed with osteoporosis, or do you have a disease which
results in a Calcium deficiency?
Growth Hormone Deficiency is directly correlated with weaker bones.
This is a bad thing for both men and women, but since women have more
naturally fragile bones, osteoporosis and calcium deficiency are more
of a threat and can lead to devastating broken bones or other
of Sermorelin Therapy
Therapy Preserves the Hypothalamic Axis
doesn't just produce more Human Growth Hormone for use by the body,
it actually regulates the proper production of HGH and its
distribution throughout the body. It does this by restoring and
preserving the Hypothalamic Axis, which degrades as we age and can
also degrade as a result of long periods of Human Growth Hormone
Replacement Therapy without taking supplementary steps to preserve
endogenous hormonal function. Think of the Hypothalamic axis as a
form of checks and balances. If one portion of the endocrine gets out
of whack, other areas of the system overcompensate or undercompensate
to make up for disturbances in other parts of the system.
primary ingredient which preserves a healthy Hypothalamic axis
appears to be Growth-Hormone Releasing Hormone, which acts as the
ultimate intermediary between the anterior pituitary and the
hypothalamus. In most patients, the pituitary is able to produce
healthy levels of Human Growth Hormone well into old age, but the
body begins to produce inferior levels of GH-RH, eliminating the
Human Body's ability to regulate the endocrine response that results
in the proper release of Human Growth Hormone, which leads to
numerous woes that are incorrectly associated with the inevitability
of Sermorelin Replacement Therapy in Patients who Suffer from Human
Growth Hormone Deficiency
and Fat Breakdown
aids patients who suffer from Human Growth Hormone Deficiency by
optimizing IGF-1 production in the Human Body. IGF-1 takes adipose
fat from problem areas of the body and breaks down the tissue for
energy usage by the rest of the body. This leads to enhanced energy
levels because the body has constant and enhanced access to energy
stores which reduce fatigue and increase endurance.
and Muscle Health
freed-up energy strengthens the muscles in two ways. Even without
exercise, increased levels of IGF-1 then pulse through our bodies as
we sleep, and give our organs the energy and tools that they
need to enhance muscle tissue even without exercise. The second way
that increased IGF-1 levels can lead to muscle growth is because the
enhanced endurance and reduced fatigue allow the patient to undergo
more vigorous exercise for longer periods of time. This increases the
strength of the body even further. There is also a biofeedback
mechanism at play here, because the enhanced endurance and ability to
exercise leads to further weight loss as a result of increased
activity. All this can occur without changes in diet, but dietary
changes can increase the results, especially in patients that are
and Physical Rejuvenation
third way that IGF-1 levels can rebuild and reshape the body is
because increased levels of the hormone give the body the energy that
it needs to restore other organs as well. After a hard session of
working out, the body spends your sleeping hours mending the minor
damage done to your body which leads to your enhanced strength as a
result of exercise. By reducing recovery time from exercise, this
increases your capacity for exercise even further!
and Bone Health
has also been proven to enhance the strength of the skeletal system
as well. Enhanced levels of Insulin-Like Growth Factor One contribute
directly to stronger teeth and bones by encouraging calcium
retention. As men and women age, it can often become harder to retain
healthy levels of calcium in the body. This is a more significant
issue for women than men. Men's bones are more structurally sound and
atrophy takes longer to accumulate. In women, however, menopause
makes them incredibly susceptible to life-threatening changes
in bone structure such as osteoporosis. Sermorelin actually
has the ability to reverse osteoporosis, maintaining the integrity of
the skeletal system and reducing the danger that slips and falls
represent to older men and women.
Better with Sermorelin
addition to these benefits, Sermorelin has been clinically proven to
help patients sleep when used before bed. Injecting Sermorelin before
going to bed at night helps preserve the natural circadian rhythm
that human beings live by. Sermorelin resets the clock, in a way,
because the natural rhythm of the body leads to peaking HGH levels as
we sleep. Sermorelin Therapy leads to deeper and more sound sleep in
which the body is able to prepare us for another day of living life
the right way.
Skin Beauty with Sermorelin
are a number of patients that report healthier skin as a result of
Sermorelin Therapy as well. IGF-1 plays an integral role in the
preservation of the intracellular fluid which connects many of the
cells of our body. Intracellular fluid is the means by which our
cells share the building blocks of life with one another. By
encouraging the optimal levels of intracellular fluid, Sermorelin
plays an important role in maximizing the efficiency at which our
individual cells have the tools to rebuild themselves and preserve
is nowhere where the benefits of this process are more apparent than
on the skin. The restoration of intracellular fluid preserves the
softness, smoothness, and suppleness of the skin. The skin is the
largest organ of the human body, and it takes more abuse than any
other organ because it is responsible for preserving the body in the
face of constant negative outside stimuli. Sufficient levels of
intracellular fluid reduce the appearance of fine lines and wrinkles
on the face by increasing the surface area of each individual skin
healthy and beautiful appearance of the skin is also the result of
healthier and stronger muscles which rest just below the skin. As the
muscles of the face become stronger and firmer, it alters the
physical appearance of our skin as well. Wrinkles and lines are
stretched out of existence. Also, our skin feels tighter and smoother
as a result of these structural changes. The foundation of our skin
provided by the muscles play just as important of a role in the
aesthetic beauty of the skin as the health of the skin itself, which
is enhanced by optimal levels of intracellular fluid. Some patients
even experience the regrowth of thinning or lost hair. Or hair that
has had its color return.
and Mental Health
of these amazing physical changes help the mind as well. Sermorelin
Therapy has been shown to alleviate depression and give patients a
newfound ability to seize the day. When the body and mind are able to
fully rejuvenate themselves, it helps to ward off the symptoms of
depression and empower us as human beings. There is evidence that
these mental and psychological changes are directly the result of
Sermorelin Therapy and not simply the result of the positive physical
changes that accrue over time. Sermorelin truly has the ability to
improve every aspect of our lives, especially if we use it as a
catalyst for self-growth which can lengthen and improve life in an
as a Treatment for Idiopathic Short Stature or Dwarfism
health issues that occur in children that suffer from HGH Sufficiency
can be even more dramatic than when adults become deficient. We all
know that Testosterone and Estrogen production play huge roles in
male and female puberty, respectively, but many don't understand the
role of Human Growth Hormone in puberty. The male and female sex
hormones produce the sexual changes associated with puberty which
further differentiate boys and girls from men and women, whereas
Human Growth Hormone is the key hormone is producing the changes in
height and stature that are a result of puberty.
children produce insufficient levels of Human Growth Hormone, they
are not able to grow to a normal adult height, which leads to a
condition known as Idiopathic Short Stature, colloquially known as
Dwarfism. There is a narrow window of time during which the height
changes associated with puberty can occur. Long bones grow during
puberty due to the effect that Human Growth Hormone has on the
epiphyseal plates. It encourages the long bones to continue to grow
throughout puberty, causing us to grow to our final adult height. At
the end of the period in which puberty occurs, the epiphyseal plates
harden at the ends of our long bones and prevent us from growing
further. The sooner that Idiopathic Short Stature can be diagnosed,
the earlier that it can be treated, thus allowing children to grow up
to be adults of a normal height.
was originally approved by the Food and Drug Administration for
children who suffer from growth issues, and has, since that time,
been discovered to provide numerous and amazing benefits to adults as
well. Since Sermorelin has been proven effective for both children
and adults, there is hope that Sermorelin can be an effective
treatment option for rare hormonal diseases such as
progeria – progeria
is a devastating disease in which children physically age at a rapid
rate, usually succumbing to their disease in their late twenties.
Though progeria is a very rare disorder, it is incredibly intriguing
to scientists and researchers, because if modern science can unlock
the secret mechanisms by which progeria occurs, they can not only
cure progeria, but learn more about the intricate genetic
and hormonal nature of the aging process itself.
as a Treatment for Cachexia
is significant scientific evidence that Sermorelin can improve
outcomes for patients who suffer from cachexia as a result of AIDs
Wasting Disease, Cancer Treatment, and even anorexia. Cachexia is
medically defined as a loss of ten percent of more in body
weight that is attributable to muscular atrophy.
who suffer from AIDs wasting disease lose the ability to preserve
their muscle strength. There are many reasons for this. One reason is
that patients lose their desire to eat, whether it be by the effects
of medications that are taking to combat the disease or the effect of
the disease itself. Another reason that AIDs patients suffer from
muscle atrophy is because the progression of the AIDs virus
can deteriorate the human body's natural ability to distribute
nutrients effectively throughout the body. Sermorelin produces
positive effects at both ends of this spectrum. For one thing,
Sermorelin can produce metabolism and encourage hunger in patients
that have trouble desiring food. In addition to this, the
rejuvenating effects of Sermorelin restore the body's ability to
distribute valuable nutrients throughout the body, giving the muscles
the tools they need to rebuild themselves. Sermorelin Treatment can
give AIDs patients the ability to live a more productive and healthy
life in spite of their disease that many patients may not have been
able to experience otherwise.
is effective in cancer patients for similar reasons. Cancer
treatments such as Radiation and Chemotherapy reduce the ability of
healthy cells to proliferate as well as cancer cells. These forms of
therapy also lead to nausea and sickness that make it
harder to eat. Sermorelin restores hunger by increasing metabolism
while also working to reverse some of the damage accumulated by
radiation and chemotherapy. These positive effects on metabolism and
growth persist in healthy cells even though the cancer therapy
continues to kill off cancerous cells.
patients who suffer from anorexia that is extreme enough to result in
cachexia, Sermorelin can be used to restore muscle atrophy that
resulted from the persisting eating disorder. Of course, Sermorelin
therapy must be combined with other forms of physical, medical, and
emotional therapy to relieve the underlying symptoms of anorexia, but
Sermorelin is particularly effective at restoring atrophied muscles
and returning them to a more healthy state.
is Human Growth Hormone Deficiency Diagnosed?
making the decision that Sermorelin Therapy might be right for you,
there are three stages to receiving a diagnosis for HGH Deficiency:
first stage is that you must fill out a medical history form. This
form will inform your physician of any ailments or issues you are
having or have had in the past. It will inform your physician of any
underlying issues that you may suffer from that may exacerbate your
hormone deficiency. It will also provide information that will ensure
that it is safe for you to go Sermorelin Therapy.
will also need to undergo a physical. The physical will inform your
prescribing physician of important factors such as your height,
weight, and muscle/fat ratio which will allow him or her to prescribe
you with a dose that will accurately suit your physical parameters.
Sermorelin is a highly potent hormone, and it is very important that
your prescribing doctor prescribe an accurate dose of the
GH-RH analogue to suit your unique hormone needs.
you will need to undergo Blood Testing. Your prescribing physician
will set up an appointment with a highly respectable and efficient
blood testing company such as LabCorp that can take your blood sample
and run a thorough battery of tests which will provide a complete
hormone panel so that your prescribing doctor has a significant
amount of diagnostic information available to make an accurate and
sensible diagnosis. It normally takes around five business days for
the results of the bloodwork to reach your Anti-Aging physician for
examination, but after your physician receives the blood diagnostics,
he or she can quickly make a diagnosis.
your Anti-Aging physician looks over all the available data and deems
you an acceptable candidate for Sermorelin Acetate Therapy, he or she
will write a prescription and discuss treatment protocols with you to
ensure that you are fully informed about how to properly use
Sermorelin. After you have received your prescription you can make an
order for Sermorelin from a reputable pharmacy such as the one on
this website. Our pharmacy can promptly and safely deliver Sermorelin
to you via Federal Express. We have the logistical capabilities to
send safely refrigerated and carefully handled Sermorelin Acetate
Therapy to your doorstep by overnight delivery.
should not take Sermorelin?
who are utilizing corticolsteroids such
as hydrocortizone, dexamethazone, and prednisone may
interact in a negative way with Sermorelin Therapy. In addition to
this, patients who are currently prescribed medicines which treat
hypothyroidism such as levothyroxine should exercise caution when
considering Sermorelin. Always listen to your physician. You may be
allowed to take these medications concurrently, but realize that
there is an enhanced risk of side effect or negative reaction.
prescribed expressly as a means to combat cachexia as a result of
radiation and chemotherapy, Sermorelin should not be used while a
patient has cancer, because under some circumstances,
excess levels of Human Growth Hormone can contribute to cancer
she has been given express permission by a physician, a woman should
avoid HGH and Sermorelin Therapy if she is pregnant. In animal tests
in which purposeful overdoses were delivered to the mother, the fetus
developed minor abnormality. With normal human treatment there
is no indication the Sermorelin Therapy has a negative effect on the
child, but there is not sufficient evidence available to claim
that birth defects or growth abnormalities are not a possibility.
Also, women who are in the process of nursing their child should not
use Sermorelin without the approval of their doctor. To date, there
has been no research conducted with regard to breast milk and
Scams are Too Good to Be True – Stick with Responsible Legal
are hundreds if not thousands of imitators out there, but Sermorelin
Therapy is only effective when delivered via subcutaneous injection.
Fraudulent websites often try to pawn off pills and sprays as
legitimate forms of therapy. Beware! These forms of Hormone
Replacement Therapy are ineffective and can even damage your body if
used for a long period of time. Patches are also a ripoff. Though
Testosterone creams and patches can be extremely effective in
treating Testosterone Deficiency, there is no cream or patch
available today that can effectively treat Human Growth Hormone
is also vitally important to only purchase Sermorelin Therapy or any
other Hormone Replacement Therapy from Reputable dealers. There are
countless websites, forums, and message boards which feature men and
women selling or pretending to sell Sermorelin or other Hormone
Replacement Therapies without a prescription. It is incredibly risky
for multiple reasons to make black market deals for Sermorelin
is highly illegal to sell Sermorelin without a prescription. It is
also just as illegal to purchase Sermorelin without a legally
attained prescription. If you make an agreement to purchase black
market Sermorelin and are caught by law enforcement officials, you
will risk jail time and face significant fines as a result of your
there is no guarantee as to the safety or strength of the product
that you eventually receive. These black market forms of Hormone
Therapies such as Sermorelin are often created in Central American
and Chinese laboratories, if not simply domestic makeshift drug labs
which combine dangerous chemicals with amateur chemists. At best you
will receive an inferior product which provides only modest physical
gains. At worst, you will receive a product that is actively
dangerous to your body and can present life-threatening consequences
with long-term usage.
Use Sermorelin with a Legitimate Deficiency
Sermorelin Therapy is incredibly effective in patients who truly
display a need for Human Growth Hormone, and our Clinic is fully
certified to legally provide Hormone Replacement Solutions for our
patients. These therapies are safe and clinically effective, with
little to no risk of adverse health effect. If you are interested in
Sermorelin Acetate Therapy or any other Hormone Replacement Therapy
that we provide, we urge you to give us a call today – we
would love to help you change the life of you or a loved one today,
and we have the capability to do so.
are a number of variables that will affect your particular
prescription for Sermorelin. Specific dosage is dependent upon your
particular age as well as your sex. Also, different individuals who
seem to be identical can be affected in significantly different ways
by the same level of Human Growth Hormone Deficiency, so the
prescription that you receive is also partially dependent upon the
type and severity of symptoms that you display.
is also vitally important to have your blood drawn at least twice a
year while on Sermorelin therapy or any other form of Hormone
Replacement Therapy in order to monitor the effectiveness of therapy
and to ensure that no physiological abnormalities occur as a result
of such therapy. If unwanted side-effects do occur, patient and
physician can discuss options to adjust the current dosage or change
Therapy is an amazing treatment option for those who suffer from
Human Growth Hormone Deficiency. In spite of this fact, Sermorelin is
not the right choice for every patient. Sermorelin is intended for
individuals who still have the ability to secrete HGH at healthy
levels, but are unable to due to a deficiency of Growth
Hormone-Releasing Hormone. If it is discovered that your body does
not respond to Sermorelin Therapy, we can discuss other therapies
such as Human Growth Hormone Replacement Therapy to remedy your
particular endocrine abnormality. We implore you to contact us today.
We have the best therapies and techniques that modern science has to
offer at our disposal, and we are driven to provide longer,
healthier, and brighter futures to our patients. We can restore your
waning vitality and provide you with the energy of your youth while
maximizing the potential of your wisdom and experience.
new Cutting-Edge Of Preventative Medicine
we're young, ample amounts of growth hormone releasing factor are
produced so that the pituitary is able to provide the body with
sufficient growth hormone to sustain health and vitality. However, as
we age, growth hormone releasing factor declines causing reduced
production and secretion of pituitary HGH often leading to a growth
hormone insufficiency that erodes health, and diminishes vigor and
Restoring medical levels of growth hormone
may improve or sustain good youthful anatomy, physiology, and
thereby, the health and vitality often lost with age-related growth
hormone deficiency. Traditionally, adult growth hormone deficiency
(AGHD) has been treated by substituting natural HGH with recombinant
human growth hormone (rhGH). Although rhGH injections are still the
standard for treating AGHD, a breakthrough product, Sermorelin,
offers a more natural, affordable alternative that is as effective as
in 1998 by Serono Laboratories, Inc., the makers of Saizen HGH, FDA
approved Sermorelin as recently become available for the treatment of
AGHD. Sermorelin is comprised of 29 amino acids found in the hormone
(GRF 1-44) that your brain produces naturally to simulate the
release of HGH. As a growth hormone releasing agent, Sermorelin
triggers the pituitary gland to produce your own natural HGH. In this
natural process, your body regulates the level and frequency of HGH
release, so there are no side effects associated with the constant
application of injected rhGH. Sermorelin requires no off-cycles. In
fact, the longer you use it, the better your pituitary gland
functions, more like it did when you were younger.
line, Sermorelin effectively re-starts your natural HGH production to
levels produced when you were younger. This not only provides the
youth-restoring benefits of HGH on body composition, it also helps
sustain pituitary health and opposes loss of activity of
the endocrine system that normally occurs with age.
should really know about Human Growth Hormone before thinking about
taking HGH therapy. Human Growth Hormone is similar to estrogen and
progesterone because it assists humans in growth. The anterior
pituitary secretes Human Growth Hormones and the one hundred ninety
one proteins that assist the body in its maturation and proper
treatments consist of a manufactured version of GHGH (The releaser of
HGH which sends the message toward the anterior pituitary to secrete
HGH) and HGH. With particular folks GHRH becomes inhibited
or dysfunctional and it will stop releasing signals properly. A
failing GHRH can make a grown up start to get old too fast.
Sermorelin injections can assist them in keeping the look of youth
R3-1 Sermorelin HGH is often provided to kids who lack it and are
having trouble growing right. In recent years the Food and Drug
Administration allowed Sermorelin to be given to people who feel they
are getting older too fast. It can also be given to those who have
HIW because it reduces a few issues related to that disease.
shots are every day, normally when it is time for bed. This will
often make sleep better because hormones are secreted at their
highest during sleep. Sex and level of aging are things that consider
the level of dosage you are given.
pros of having HRT include less lines and bouncier skin and
higher energy. Those who have bone density problems will discover a
difference too. Other pros are more strength and greater lean muscle,
dropping a lot of fat in the tissues, higher sex-drive, and greater
sex function capability.
Sermorelin regimen is used by physicians to treat the kidneys.
Physicians discovered that function of the kidneys is made stronger,
and memory is stronger too. Problems with hypertension will likely
lessen or be eliminated. The immune system can become stronger and it
might make the hair grow back on your head and thicker.
are some possible side effects, though, in combination with the
benefits. The most reported is swelling and pain at the
shot site. Other serious issues include problems swallowing and
itchiness. Very rare but very serious issues that may arise are
vomiting, hyperactivity, headache, and dizziness. These should be
told to a doctor.
who thinks therapy with Sermorelin could be right for them should
talk to a doctor about it. There are many physicians who are allowed
to give the therapy all over the United States, and there exists many
places that will be able to give therapy to all of those who have
Hormone Deficiency Onset in Adulthood. Participants are monitored
with care and testing. Laboratory work is used to guarantee that a
person is benefiting properly. This is prescription-required therapy
and could cost a person $2000-$3000.
Treatment is a great way to assist those that have an HGH deficiency
and look old too fast. It will also make their mind feel younger in
addition to restoring a more youthful look.
is one of the most common injectable Hormonal supplementation
therapies used today to increase IGF-1 production, and it works
successfully by directly leading to the internal production of more
Human Growth Hormone (HGH) circulating in the body. Sermorelin works
as a secretegogue analog of the hormone Growth Hormone
Releasing Hormone (GHRH) that tells the pituitary gland to release
more HGH. In order to fully understand what Sermorelin is and how it
works, it is important to fully understand why and how Human Growth
Hormone is secreted from the pituitary gland and how it
travels to the liver to stimulate IGF-1 production.
Sermorelin Replacement Therapy and the Pituitary Hypothalamic Axis
affects the body by not just releasing, but regulating HGH. It is an
analog secretegogue hormone supplement that works in the
same fashion as the hormone secretegogue Growth Hormone
Releasing Hormone (GHRH), but more importantly it works
with the hypothalamic pituitary complex which has checks
and ballances, whereas HGH injections alone, may not
work as effectively with the hypothalamic pituitary axis.
Injections as an Affordable Hormone Treatment Program
days we understand that hormones are essential to the regulation of
the multitude of bodily functions. There can be significant medical
and health problems when hormones are not secreted in the proper
amounts, either too much or too little. This is doubly true for
Growth Hormone and its essential precursor GHRH released from the
hypothalamus. Many of the issues associated with decline hormones can
also arise when the body is not properly releasing Growth Hormone
Releasing Hormone (GHRH). This can lead to improper secretion of
Growth Hormone. There are numerous reasons why the body doesn't
produce enough HGH, one of the most significant reasons is thought to
be as a result in declining GHRH and this is why Sermorelin, not just
HGH therapy is so important.
Discovered the Human Body Can Secrete HGH at any Age, even "Old
body is perfectly capable of creating the proper amount of Growth
Hormone, but when GHRH does not send the hormone chemical message to
the anterior pituitary then it's time to supplement more of the
hormone. Often, people need to take bio-identical genetically
synthesized hormone supplementation like Sermorelin to raise hormone
production up to normal levels, so that health issues can be
alleviated or prevented. Injections of Sermorelin have been proven to
be very effective at restoring youthfulness and keeping the body
Injection Doses By Hormone Physician Prescription
using Sermorelin properly and with correct dosage, vigor, strength,
healthier hair, improved skin and proper muscular function
can be restored. There are a large number of potential benefits to
using Sermorelin to assist in the regulation of Human Growth Hormone,
and there are a number of conditions that Sermorelin is used to
can reduce recovery time after injury or general physical activity,
improve sleep, provide a rejuvenated sense of well being when waking
up, reduce body fat, and alleviate depression. Some patients have
reported that they had less gray hair growth. Most people report it
reduces wrinkles, fine lines and thin saggy skin. These are
just a few benefits that Sermorelin patients report.
and Sermorelin with Dwarfism or Short of Stature
are health problems that occur in children where the production of
Human Growth Hormone (HGH) is suppressed. These children often become
afflicted with a condition known as dwarfism or short stature. They
do not grow up like normal children do, and thus remain short for
their entire lives.
is also FDA-approved for dwarfism. Sermorelin is also approved as a
treatment for premature aging as well. For this reason, it is also
possible that Sermorelin could treat rare disorders such as progeria,
which cause children to grow physically old at a very fast
rate. They pass away before they reach their thirties.
and AIDS: Muscle Wasting and Weight Balance
has also been shown to improve many symptoms associated with HIV in
many cases, for instance reversing unhealthy muscle wasting and
weight loss. Many people are overweight, but with AIDS, what often
happens is people become underweight. Healthy weight is in
the median of these two extremes. There are many ailments and
illnesses that can be treated by Sermorelin and proper medical
counseling is first required. These treatments can help patients live
fit and productive lives that they would not have the opportunity to
without treatment, presuming they are deficient in hormones, an
inevitable part of aging.
Deficiency Testing and Lab Work for Sermorelin Therapy
testing is needed to determine exactly how much Sermorelin an
individual patient needs, if at all, deficiency is required or if you
are continuing therapy. Sermorelin is administered through injection
to maximize the effectiveness of the hormone, because there
is no other way to administer it. Hundreds of web sites are
hawking HGH or Sermorelin pills, sprays, patches and incense - these
are unadulterated scams. Only through injections can Sermorelin be
administered. The injections are performed at night before bed
because this is the time at which the pituitary gland releases the
most Human Growth Hormone, especially in the 7th and
of sleep. Sermorelin also provides a better night's sleep and
alleviates the fatigue and irritability of those suffering from a
growth hormone deficiency, while enhancing the individual's ability
to become more engaged with life. One of the most significant things
you will notice when you do sermorelin injections at night on an
empty stomach is you wake up feeling very rejuvenated.
specific dose of Sermorelin depends upon the sex of the individual as
well as the age-related symptoms or medical conditions they are
experiencing. The patient should be regularly monitored to make sure
that the body is properly tolerating the dosage of Sermorelin that is
being administered in private at home. By doing this, the doctor and
patient can minimize side effects and discomfort that can be
associated with taking too much Sermorelin.
Most Obvious Benefits of Sermorelin Injections
the many benefits of using Sermorelin to treat patients with Human
Growth Hormone deficiencies are smoother skin with fewer
wrinkles, stronger muscles with more elasticity, and an overall
increase in vigor and strength. Levels of unhealthy body fat also
decrease, especially around the hard-to-treat midsection. Increased
libido and sexual ability are also commonly recorded benefits to
Injections and Internal Medicine
immune system also becomes stronger, along with the filtration
ability of the kidneys and the cognitive ability of the brain.
Throughout treatment, one should regularly consult our
endocrinologist and internal medicine physician about their Human
Growth Hormone levels. They should inform our doctor of any and all
discomfort and side-effects that they experience as they go through
therapy. Each person has a different set of needs, and the effects of
Sermorelin therapy will be different for every patient.
is not available without prescription, and our hormone clinic
has authorization to undertake and administer Sermorelin
therapy, as well as other hormone therapy programs. Never choose a
clinic that does not specialize in HRT. The patient should choose
another provider for his or her own health and safety. We hope you
will choose us as we are a reputable HRT medical clinic. Before
starting Sermorelin therapy, have a thorough physical performed by
your general practitioner or other health professional, then
call us and we will schedule you to have a blood test. We specialize
in hormone therapy and prescribe doses accurately.
Started With Sermorelin Acetate Injections
learn more about Sermorelin or any other of our hormone treatment
options, contact us today at Bio-Identical Hormone Replacement
Therapy MD, the Conscious Evolution Medical Institute and ask to
speak with one of our many clinical specialists.
isn't right for everyone, but it may be right for you. Sermorelin is
used for those patients that are still able to properly produce Human
Growth Hormone, but do so in diminished amounts. If the
body is not capable of producing the hormone, we will discuss other
treatment options with you such as direct Growth Hormone Therapy. Our
staff has everything that you need to start a better life with
Hormone Replacement Therapy!