Written by , Article reviewed and edited by Dr. Fine M.D..
Published on November 28th, 2018
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What is Sermorelin?
Sermorelin is a synthetic drug which is derived from GH-RH, which is also known as Growth Hormone-Releasing Hormone. GH-RH is the hormone responsible for the production of Human Growth Hormone, commonly referred to as HGH. GH-RH is secreted by the hypothalamus and functions as a chemical messenger which sends the signal to the pituitary to secrete more Human Growth Hormone to be delivered throughout the body.
Sermorelin is not naturally produced by the human body, but it is functionally identical to Growth-Hormone Releasing Hormone produced by the human body. Sermorelin contains the same initial 44 proteins that are present in GH-RH, and scientists and researchers have discovered that this truncated version of Growth Hormone-Releasing Hormone is the shortest known derivative that produces an identical effect upon the body as GH-RH, which is to enhance pituitary secretion of HGH.
HGH and Human Development
In our preteen and early teenage years, Human Growth Hormone is primarily responsible for the increase in growth rate associated with puberty. Children that suffer from a deficiency in Growth Hormone-Releasing Hormone do not produce sufficient levels of Human Growth Hormone and therefore do not grow at the same rate as their peers. Human beings complete the process of normal growth and reach their final adult height after the epiphyseal plates of their long bones close at the end of puberty.
After this point, the role of Human Growth Hormone changes, yet the role of GH-RH remains the same. After puberty, the body needs to produce sufficient levels of Growth Hormone-Releasing Hormone that allow the body to secrete the HGH that it needs to sustain itself at peak condition, allowing us to enjoy maximum vitality and health. GH-RH allows the body to function optimally as it was meant to function.
With Age, GH-RH Levels Decline
Unfortunately, production of Growth Hormone-Releasing Hormone by the pituitary drops as we age, and this reduction in endogenous production of GH-RH is directly correlated with reduced release of Human Growth Hormone, which inevitably leads to a rapidly sped up aging process. At age twenty, the human body produces an optimal level of adult Human Growth Hormone around five hundred micrograms each day. By the time we reach our late twenties to early thirties, the levels of endogenous Human Growth Hormone that we produce decreases at a seemingly marginal rate of one to two percent each year. Over time, however, this constant decline accumulates, leaving our bodies grossly deficient in Human Growth Hormone. By the time we reach the age of eighty, the human body only secretes around sixty micrograms of Human Growth Hormone daily often even less! In otherwise healthy adults, an HGH level of around two hundred micrograms is considered low.
The effects of Human Growth Hormone Deficiency begin to become more pronounced as we enter our late thirties and early forties. At this point, our deficiency in Human Growth Hormone begins to greatly under-perform and our bodies start to age more rapidly. Rapid aging is not inevitable, however. And Sermorelin Therapy is a fantastic means by which to alleviate the effects of age in a way that allows us to grow old in a healthy way that does not take from us our vitality.
HGH Therapy vs. Sermorelin Therapy
Human Growth Hormone Replacement Therapy is effective at treating Human Growth Hormone Deficiency, but it may not be the most efficient way to restore optimal hormone production. It may only be covering up an underlying problem.
HGH Hormone Replacement Therapy simply replaces endogenous Human Growth Hormone with HGH from an outside source. Sermorelin works by increasing the level of HGH naturally secreted by the body, which leads to more natural release of the hormone throughout the body when and where it is needed. Sermorelin treats underlying neuroendocrine failure which leads a large number of patients who suffer from Human Growth Hormone Deficiency while having a perfectly healthy pituitary function.
For these patients, Sermorelin Hormone Replacement Therapy produces more natural physiological function while also being safer and having a significantly lower risk for unwanted side-effects than simply treating the symptoms of Human Growth Hormone Deficiency rather than the root cause. In addition to this, Sermorelin Hormone Replacement Therapy is not restricted in the same manner as HGH Hormone Replacement Therapy for use in patients that suffer from HGH Deficiency.
Benefits of Sermorelin:
Below are just a few of the Benefits of Sermorelin Therapy:
- Sermorelin enhances the Pituitary Gland's natural ability to produce endogenous Human Growth Hormone, leading to a more natural Hormone Profile<
- Sermorelin optimizes the human body, increasing physical and mental performance
- Sermorelin strengthens immune health
- Sermorelin boosts the liver's production of Insulin-Like Growth Factor One
- Sermorelin helps patients sleep longer, deeper, and better
Restoring Endocrine Function with Sermorelin
As a result of generations of Anti-Aging and longevity science, we realize today that Hormonal Balance is the key to preserving the optimal function of the many organ systems that make up the human body. When hormones are not released in sufficient amounts, or when certain hormones are produced in excess, the body can suffer greatly as a result. This is more apparent regarding HGH and its correlated secretagogue, Growth Hormone-Releasing Hormone, than with any other hormones produced by the body. A myriad of issues that are correlated with the process of aging are intricately connected to insufficient levels of GH-RH and HGH in the brain and in the blood stream. Though there are a multitude of reasons why the body produces less Human Growth Hormone as we age, among the most prominent and easily resolved issues is GH-RH Deficiency, which can easily and safely be restored with Sermorelin Therapy.
What Makes Sermorelin Preferable to HGH Hormone Replacement Therapy?
The effects of HGH injections are not well-regulated by the body. If a person administers too much Human Growth Hormone, the body has no way of negating the effects of the flood of HGH entering the body. The pituitary gland may depress over time and release less endogenous HGH to compensate, but the body will still over-react to excess levels of HGH that occur as a result of overdose or abuse. This reduced level of endogenous HGH production is actually a bad thing, because once an individual suspends HGH injections, the body will not be able to produce the same levels of Human Growth Hormone as it once did until it slowly increases its natural production again over a significant period of time.
HGH and Negative Feedback
On the other hand, the effects of excess synthetic GH-RH are regulated in two ways by the body. One way is by means of negative feedback. Via negative feedback, the pituitary gland sends a message to the hypothalamus telling it that it no longer needs to produce more Human Growth Hormone. The second manner by which Human Growth Hormone production is regulated when using Sermorelin is by somatostatins.
Somatostatin HGH Inhibitor
Somatostatins are hormones which prevent the pituitary from taking up excess levels of Growth-Hormone Releasing hormone, thereby preventing the Pituitary Gland from producing excess levels of HGH. By means of these binary inhibitory factors, the risks associated with Human Growth Hormone are minimized, and when Sermorelin is used correctly with a physician's prescription, the side-effects of HGH overdose will likely be completely eliminated.
Sermorelin is Safer and More Natural than HGH Hormone Replacement Therapy
Patients who use HGH Hormone Replacement Therapy are at a slightly enhanced risk of joint disorders such as Arthritis and Carpal Tunnel Syndrome. Older patients may find this reason enough to forgo HGH Therapy for Sermorelin Therapy. In addition to this, patients who undergo Human Growth Hormone Replacement Therapy sometimes suffer from temporary blood sugar fluctuations as a result of surging or quickly dissipating IGF-1 levels. These effects are not present when using Sermorelin Therapy.
Another way that Sermorelin Therapy is superior to HGH Hormone Replacement Therapy in many patients is that Sermorelin encourages a more natural production of Human Growth Hormone by the body. Sermorelin Therapy leads to episodic production of Human Growth Hormone, which is the manner by which the human body naturally secretes Human Growth Hormone. HGH is secreted by the pituitary gland in pulses which quickly dissipate throughout the body, where it is eventually converted into IGF-1 by the liver.
One patient group that may prefer Human Growth Hormone Replacement Therapy are patients that are interested in faster results at the expense of taking a bit of risk. Sermorelin Therapy takes a bit longer to produce physiological changes, but there is only a minimal chance of side effects as a result of therapy.
When undergoing Human Growth Hormone HRT, HGH is released into the body from the injection in a square wave. This means that the body is initially exposed to a high level of HGH which slowly dissipates between administrations, rather than in the natural spurts of production that the body is accustomed to. By preserving normal physiological production of Human Growth Hormone, a phenomenon known as tachphylaxis is prevented. Tachphylaxis is the phenomenon by which the body responds to an excess or constant level of a particular medicine or hormone by developing a sudden and increased resistance to that medicine or hormone, reducing its effect on the body. Some physicians who recommend Human Growth Hormone Therapy will accompany it with a certain level of Sermorelin Therapy as a means to prevent the pituitary gland from reducing its activity in the wake of increased exogenous Human Growth Hormone.
It is important to supplement the natural hormone production of the body in as natural of a manner as possible so that we may preserve the natural neuroendocrine axis that HGH is an important component of. As we age this axis becomes more and more fragile and prone to degradation and insufficiency.
Frequently Asked Questions Regarding Sermorelin
What is Sermorelin?
Sermorelin is a synthetic hormone which is functionally identical to Growth-Hormone Releasing Hormone (GH-RH), otherwise known as Growth Hormone Releasing Factor (GRF). In many scientific papers, Sermorelin is referred to as GRF 1-29 NH2.
Is Sermorelin Chemically Identical to GH-RH?
No. Sermorelin only consists of the initial twenty-nine amino acids that make up GH-RH However, even though Sermorelin differs biologically from GH-RH, the human body treats the two substances the exact same way in the body. GH-RH features an amino acid chain which is 44 peptides in length.
What type of cells produce GH-RH?
GH-RH is manufactured by the neurosecretatory cells in the human brain. Neurosecretatory cells are specific neurons which take neurological signals from other parts of the brain and convert them into chemical messengers to distribute to other parts of the brain or throughout the body.
Who discovered GH-RH?
GH-RH was initially characterized by A. Shalley and R. Guilleman during the 1970s thanks largely to the efforts of their student W. Wehrenberg. Wehrenberg was interested in determining which portion of the Human Growth Hormone molecule was necessary to stimulate the pituitary gland. After a period of trial and error in which he deleted individual acids from the peptide sequence, he eventually reached a tipping point after which, the hormone no longer produced stimulative action. He discovered that, after deleting the last 16 amino acids from the peptide chain, the first twenty nine amino acids were the only necessary peptides needed to stimulate the endogenous manufacture and secretion of Human Growth Hormone. This is the ultimate reason why Sermorelin's chemical notation is GRH 1-29 NH 2. The final portion of the notation, NH2, represents the final amino acid of GH-RH.
Are Human Growth Hormone and Sermorelin Biologically Identical?
Sermorelin and Human Growth Hormone are unique substances that stimulate different hormonal functions within the human body. Sermorelin functions as a precursor for the production of HGH. A Human Growth Hormone Precursor is also known as an HGH Secretagogue. This is a simplified way of saying that Sermorelin activates the pituitary gland, thereby stimulating the production and secretion of HGH throughout the body. Sermorelin is significantly smaller than Human Growth hormone. HGH is the largest hormone produced by the human body, at a length in at 191 amino acids, whereas Sermorelin is tiny in comparison, consisting of only 29 of those acids.
What are OTC HGH Secretagogues? Are they the same as Sermorelin?
No, Over the counter secretagogues, also known as Human Growth Hormone Releasers, are something completely different than Sermorelin. Commonly advertised HGH Releasers consist of amino acids such as L-dopa, glycine, L-ornithine, L-glutamine, and L-arginine. Herbal supplements such as Tribulus terrestris and Macuna pruriens are also often advertised as HGH Releasers, as well as the substance ornithine alpha-ketoglutarate. It is true that with a significantly high dosage of a concoction of any of these HGH releasers can sometimes produce a pituitary response in which Human Growth Hormone is secreted, the effect that it produces is not specific. This means that the effect that HGH Releasers have on the brain will affect the entire brain and not specifically one specific region. Sometimes this results in the secretion of Human Growth Hormone. Exercise also has a non-specific effect on the body, stimulating the entire brain. The effect of these Human Growth Hormone Releasers is unreliable and sporadic, however, because there is no simple and specific process by which any of the ingredients directly stimulate the pituitary.
Are OTC HGH Secretagogues and Hormone Releasers Safe?
At best they will be inert, and at worst they can be highly damaging to the body. Because HGH Releasers require high doses to show any level of effectiveness, they can be very bad for the liver. After the ingredients of the HGH Releaser are digested by the stomach they are delivered to the liver which attempts to break them down. The liver is not optimized to break down large amounts of these amino acids and can deteriorate over time as a result. The kidneys also suffer in a similar fashion.
Is Sermorelin Safe?
In short: yes. Since Sermorelin is injected rather than digested, it bypasses the liver and kidneys and is delivered directly to the brain where it is needed. Sermorelin bonds to very specific kinds of receptors located on the somatotrophs of the pituitary gland. These somatotrophs are very efficient at absorbing Sermorelin as it is needed. In addition to this, Sermorelin injections feature significantly fewer amino acids. The body responds actively to a very small amount of Sermorelin; therefore, there is no reason to flood the body and brain with excess amino acids which will only tax the liver and the kidney. When used appropriately, Sermorelin is incredibly safe and produces very limited side effects in a minority of patients.
Why Should I Consider Sermorelin When HGH Therapy Has Been Proven Effective?
There are several reasons to consider Sermorelin over Human Growth Hormone. Yes, it is true that Sermorelin and Human Growth Hormone Replacement Therapy produce the same positive effects on the human body, but there are advantages to Sermorelin Therapy which make it a much better option for a significant number of patients. Sermorelin largely eliminates the risk of Human Growth Hormone overdose, because the body regulates GH-RH and Sermorelin in a way that it is not capable of regulating Human Growth Hormone. If too much Sermorelin is present in the body, then the pituitary gland sends messages to the hypothalamus telling it to drop endogenous production of Growth Hormone-Releasing Hormone. In addition to this, the Hypothalamus produces Somatostatins which reduce the amount of Sermorelin or GH-RH that the Pituitary Gland can absorb.
In addition to this, Sermorelin produces a natural ebb and flow of Human Growth Hormone Production which is just not possible when using Human Growth Hormone Injections. HGH Injections simply splash the blood stream with Human Growth Hormone which slowly recedes throughout the day. Also, by stimulating the pituitary gland in a natural way, Sermorelin stimulates the pathway of blood vessels which connect the hypothalamus and the front portion of the pituitary gland. This pathway is known as the hypophyseal portal system. In addition to all of this, off-label usage of Sermorelin is not a violation of American Federal law, whereas there are strict limitations which prevent the Off-Label use of Human Growth Hormone Therapy.
Do I Have to Inject Sermorelin?
As of today, the only means by which to deliver Sermorelin is by means of subcutaneous injection. There is an active theory that it may be possible to deliver Sermorelin via a nasal spray, but this is still hypothetical and there is no proof that such a method is viable. There is theoretical evidence that it may be possible, because, although it has been proven that Human Growth Hormone cannot be delivered via nasal spray, it may be possible for Sermorelin to navigate the nasal mucousa barrier because Sermorelin is a significantly smaller molecule than HGH. Clinical tests are currently underway, and the results of these tests should be released relatively soon.
How much does Sermorelin Therapy cost, and how does this relate to Human Growth Hormone HRT?
Sermorelin Therapy is about ten to fifteen percent cheaper per vial than Human Growth Hormone Replacement Therapy. In addition to this, a vial of Sermorelin can last as long as thirty days for a patient, whereas a vial of Human Growth Hormone generally lasts approximately two weeks. This means that Sermorelin is significantly less expensive than Human Growth Hormone Replacement Therapy while also producing greater and safer results for patients who suffer from HGH Deficiency.
How does one compare the effective doses of Sermorelin and Human Growth Hormone?
It takes around the same amount of Human Growth Hormone to produce a sufficient effect as it does when one takes Sermorelin. This is true in spite of the fact that the two hormones produce their effect in different areas of the body. Sermorelin stimulates the pituitary gland, whereas Human Growth Hormone Therapy bypasses the brain entirely, functioning through its relationship with the liver. The same amount of both hormones leads to similarly increased levels of Insulin-Like Growth Factor One. It is important to note, however, that Sermorelin is measured in micrograms generally, whereas Human Growth Hormone is prescribed in International Units.
Oftentimes, the effects of Human Growth Hormone Therapy diminish after Several Consecutive Months of Continuous Use. What Causes This, and Does This Also Occur with Sermorelin Therapy?
It is absolutely normal for Human Growth Hormone Replacement Therapy to lose some of its potency after a half year or more of treatment. This is not the result of faulty Bio-Identical HGH or a fluke in the individual chemistry of a patient. The body begins to develop a resistance to HGH Hormone Replacement Therapy because the body is inundated with levels of Human Growth hormone that are abnormally high for periods of several hours daily. It's simply the nature of Subcutaneous HGH Therapy. In addition to this, the constant release of Human Growth Hormone in the body leads to a correlated abnormal increase in Insulin-Like Growth Factor One levels in the body which leaves organic tissues more inundated with IGF-1 than they are normally accustomed to. These aspects of Human Growth Hormone Replacement Therapy cause the tissues of the body to regulate their intake of IGF-1 in response to the influx of the hormone, reducing the effectiveness of each IGF-1 molecule.
The body is accustomed to occasional pulses of Human Growth Hormone throughout the day, leading to a natural ebb and flow of HGH and IGF-1 available to the body. When undergoing Sermorelin Therapy, the pituitary and hypothalamus are able to control the level of Human Growth Hormone distributed to the body, optimizing its release to when it is needed by the body to function optimally. This gives the organs and tissues of the body time to recover from periods of IGF-1 stimulation. Because of this significantly different way in which Sermorelin functions in the human body, the effectiveness of Sermorelin Therapy does not atrophy over time.
Can Sermorelin Treat Other Disorders Which Are Not Specifically Tied to the Endocrine System?
It appears that this is the case. It is proven in one field in particular that Sermorelin has beneficial effects: The area of Sleep Study. There is significant clinical evidence that suggests that Sermorelin and Growth-Hormone Releasing Hormone can aid patients who have trouble sleeping by stimulating Stage 4 Deep Non-Rapid Eye Movement Sleep. Taking Sermorelin injections nightly allows the body to develop a natural sleeping rhythm that assists the patient in achieving a longer and more restful sleep. There are likely other non-endocrine benefits to Sermorelin as well, but this field of study is relatively new.
What is the proper schedule for administering Sermorelin?
Sermorelin is most effective when injected subcutaneously once each day before going to bed. This is vitally important, because the body naturally produces more Growth Hormone-Releasing Hormone while we sleep, so injecting at night helps mimic the body's natural Human Growth Hormone secretion schedule. It is also recommended not to eat late meals when undergoing Sermorelin Therapy. Going to sleep with a stomach that is empty will aid the circadian rhythm and help the body focus on repair and rejuvenation rather than digestion.
What should I do if I happen to miss a Sermorelin dose?
If you miss a dose of Sermorelin, don't worry. It's not the end of the world. Just wait until the next night and take your routine normal dose of Sermorelin at that point. There is no benefit to doubling up doses to try to make up for a missed dose, so we advise against it fervently.
Symptoms of Adult Human Growth Hormone Deficiency
There are a number of symptoms of the aging process that can be at least partially the result of HGH Deficiency. The more of these symptoms that you suffer from at the same time, the more likely your personal issues are the result of Human Growth Hormone Deficiency:
Are you overweight?
Individuals who suffer from Hormone Deficiency are often overweight for their age and height. This added weight tends to accumulate around the midsection. Adipose fat deposits develop on the stomach, hips, and thighs. These fat deposits are the hardest to get rid of, even with increased exercise and improved diet.
Do you suffer from anxiety or depression?
HGH Deficiency can destabilize your mood which can lead to general dysthymia or even extreme depression. Such deficiency can also lead to elevated levels of stress which are correlated with high levels of cortisol. The effects of anxiety and depression are exacerbated by physical symptoms of Human Growth Hormone Deficiency.
Do you have high levels of LDL (Bad) Cholesterol or lower levels of HDL (Good) Cholesterol?
Human Growth Hormone Deficiency leads to reduced metabolism This reduced level of metabolism can result in poor cholesterol levels which are a precursor for life-threatening illnesses such as heart attack, stroke, and cardiovascular disease.
Do you find yourself exhausted by midday, or do you find yourself unable to wake up in the morning?
HGH Deficiency can lead to many issues regarding your ability to keep your game face on throughout the entire day. HGH Deficiency is intricately related to sleep disorders which prevent you from getting the deep and restful sleep you need to be a fully functional human being. Also, poor metabolism prevents your body from getting the juice it needs from your dietary habits, leaving you listless and weary when you should be vibrant and on point. This generalized fatigue can leave you unable to take advantage of life's great opportunities and joys.
Are you experiencing a decreased sex drive or inability to perform in Bed?
Human Growth Hormone Deficiency can have devastating effects in the bedroom. The pressures of anxiety, depression, and negative self-image all combine in a way that can genuinely lead to your disinterest in sex. Reduced endurance can leave you exhausted and unable to perform at the level you once were able. In addition to this, issues with obesity and blood pressure can easily hinder your ability to be physically ready for sex as a man.
Do you feel that you are not as strong as you once were? Do your muscles lack the definition they once had?
HGH Deficiency has significant effects on muscle mass. HGH plays a crucial role in the maintenance of the muscles, and without the rejuvenating effects of healthy levels of Human Growth Hormone, your body will inevitably begin to lose its ability to maintain muscle mass. This reduction in muscle mass will directly lead to a reduction in overall strength.
Do you suffer from diminished levels of endurance or physical stamina? Can you not work out as intensely or as hard as you once did?
Insulin-Like Growth Factor One is one of the key means by which the human body releases energy for physical activity. IGF-1 breaks down stores of adipose fat, converting that fat into usable energy. HGH levels spike more often during strenuous cardiovascular activity so that that HGH can be converted to IGF-1 which will provide much-needed fuel for exercise. If you suffer from Human Growth Hormone Deficiency, this energy pipeline is much less efficient and, as a result, the body is much less equipped for long and vigorous workouts.
Have you been diagnosed with osteoporosis, or do you have a disease which results in a Calcium deficiency?
Human Growth Hormone Deficiency is directly correlated with weaker bones. This is a bad thing for both men and women, but since women have more naturally fragile bones, osteoporosis and calcium deficiency are more of a threat and can lead to devastating broken bones or other skeletal impairments.
Benefits of Sermorelin Therapy
Sermorelin Therapy Preserves the Hypothalamic Axis
Sermorelin doesn't just produce more Human Growth Hormone for use by the body, it actually regulates the proper production of HGH and its distribution throughout the body. It does this by restoring and preserving the Hypothalamic Axis, which degrades as we age and can also degrade as a result of long periods of Human Growth Hormone Replacement Therapy without taking supplementary steps to preserve endogenous hormonal function. Think of the Hypothalamic axis as a form of checks and balances. If one portion of the endocrine gets out of whack, other areas of the system overcompensate or undercompensate to make up for disturbances in other parts of the system.
The primary ingredient which preserves a healthy Hypothalamic axis appears to be Growth-Hormone Releasing Hormone, which acts as the ultimate intermediary between the anterior pituitary and the hypothalamus. In most patients, the pituitary is able to produce healthy levels of Human Growth Hormone well into old age, but the body begins to produce inferior levels of GH-RH, eliminating the Human Body's ability to regulate the endocrine response that results in the proper release of Human Growth Hormone, which leads to numerous woes that are incorrectly associated with the inevitability of aging.
Benefits of Sermorelin Replacement Therapy in Patients who Suffer from Human Growth Hormone Deficiency
Sermorelin and Fat Breakdown
Sermorelin aids patients who suffer from Human Growth Hormone Deficiency by optimizing IGF-1 production in the Human Body. IGF-1 takes adipose fat from problem areas of the body and breaks down the tissue for energy usage by the rest of the body. This leads to enhanced energy levels because the body has constant and enhanced access to energy stores which reduce fatigue and increase endurance.
Sermorelin and Muscle Health
This freed-up energy strengthens the muscles in two ways. Even without exercise, increased levels of IGF-1 then pulse through our bodies as we sleep, and give our organs the energy and tools that they need to enhance muscle tissue even without exercise. The second way that increased IGF-1 levels can lead to muscle growth is because the enhanced endurance and reduced fatigue allow the patient to undergo more vigorous exercise for longer periods of time. This increases the strength of the body even further. There is also a biofeedback mechanism at play here, because the enhanced endurance and ability to exercise leads to further weight loss as a result of increased activity. All this can occur without changes in diet, but dietary changes can increase the results, especially in patients that are overweight.
Sermorelin and Physical Rejuvenation
A third way that IGF-1 levels can rebuild and reshape the body is because increased levels of the hormone give the body the energy that it needs to restore other organs as well. After a hard session of working out, the body spends your sleeping hours mending the minor damage done to your body which leads to your enhanced strength as a result of exercise. By reducing recovery time from exercise, this increases your capacity for exercise even further!
Sermorelin and Bone Health
Sermorelin has also been proven to enhance the strength of the skeletal system as well. Enhanced levels of Insulin-Like Growth Factor One contribute directly to stronger teeth and bones by encouraging calcium retention. As men and women age, it can often become harder to retain healthy levels of calcium in the body. This is a more significant issue for women than men. Men's bones are more structurally sound and atrophy takes longer to accumulate. In women, however, menopause makes them incredibly susceptible to life-threatening changes in bone structure such as osteoporosis. Sermorelin actually has the ability to reverse osteoporosis, maintaining the integrity of the skeletal system and reducing the danger that slips and falls represent to older men and women.
Sleep Better with Sermorelin
In addition to these benefits, Sermorelin has been clinically proven to help patients sleep when used before bed. Injecting Sermorelin before going to bed at night helps preserve the natural circadian rhythm that human beings live by. Sermorelin resets the clock, in a way, because the natural rhythm of the body leads to peaking HGH levels as we sleep. Sermorelin Therapy leads to deeper and more sound sleep in which the body is able to prepare us for another day of living life the right way.
Enhance Skin Beauty with Sermorelin
There are a number of patients that report healthier skin as a result of Sermorelin Therapy as well. IGF-1 plays an integral role in the preservation of the intracellular fluid which connects many of the cells of our body. Intracellular fluid is the means by which our cells share the building blocks of life with one another. By encouraging the optimal levels of intracellular fluid, Sermorelin plays an important role in maximizing the efficiency at which our individual cells have the tools to rebuild themselves and preserve our vitality.
There is nowhere where the benefits of this process are more apparent than on the skin. The restoration of intracellular fluid preserves the softness, smoothness, and suppleness of the skin. The skin is the largest organ of the human body, and it takes more abuse than any other organ because it is responsible for preserving the body in the face of constant negative outside stimuli. Sufficient levels of intracellular fluid reduce the appearance of fine lines and wrinkles on the face by increasing the surface area of each individual skin cell.
The healthy and beautiful appearance of the skin is also the result of healthier and stronger muscles which rest just below the skin. As the muscles of the face become stronger and firmer, it alters the physical appearance of our skin as well. Wrinkles and lines are stretched out of existence. Also, our skin feels tighter and smoother as a result of these structural changes. The foundation of our skin provided by the muscles play just as important of a role in the aesthetic beauty of the skin as the health of the skin itself, which is enhanced by optimal levels of intracellular fluid. Some patients even experience the regrowth of thinning or lost hair. Or hair that has had its color return.
Sermorelin and Mental Health
All of these amazing physical changes help the mind as well. Sermorelin Therapy has been shown to alleviate depression and give patients a newfound ability to seize the day. When the body and mind are able to fully rejuvenate themselves, it helps to ward off the symptoms of depression and empower us as human beings. There is evidence that these mental and psychological changes are directly the result of Sermorelin Therapy and not simply the result of the positive physical changes that accrue over time. Sermorelin truly has the ability to improve every aspect of our lives, especially if we use it as a catalyst for self-growth which can lengthen and improve life in an astounding way.
Sermorelin as a Treatment for Idiopathic Short Stature or Dwarfism
The health issues that occur in children that suffer from HGH Sufficiency can be even more dramatic than when adults become deficient. We all know that Testosterone and Estrogen production play huge roles in male and female puberty, respectively, but many don't understand the role of Human Growth Hormone in puberty. The male and female sex hormones produce the sexual changes associated with puberty which further differentiate boys and girls from men and women, whereas Human Growth Hormone is the key hormone is producing the changes in height and stature that are a result of puberty.
When children produce insufficient levels of Human Growth Hormone, they are not able to grow to a normal adult height, which leads to a condition known as Idiopathic Short Stature, colloquially known as Dwarfism. There is a narrow window of time during which the height changes associated with puberty can occur. Long bones grow during puberty due to the effect that Human Growth Hormone has on the epiphyseal plates. It encourages the long bones to continue to grow throughout puberty, causing us to grow to our final adult height. At the end of the period in which puberty occurs, the epiphyseal plates harden at the ends of our long bones and prevent us from growing further. The sooner that Idiopathic Short Stature can be diagnosed, the earlier that it can be treated, thus allowing children to grow up to be adults of a normal height.
Sermorelin was originally approved by the Food and Drug Administration for children who suffer from growth issues, and has, since that time, been discovered to provide numerous and amazing benefits to adults as well. Since Sermorelin has been proven effective for both children and adults, there is hope that Sermorelin can be an effective treatment option for rare hormonal diseases such as progeria progeria is a devastating disease in which children physically age at a rapid rate, usually succumbing to their disease in their late twenties. Though progeria is a very rare disorder, it is incredibly intriguing to scientists and researchers, because if modern science can unlock the secret mechanisms by which progeria occurs, they can not only cure progeria, but learn more about the intricate genetic and hormonal nature of the aging process itself.
Sermorelin as a Treatment for Cachexia
There is significant scientific evidence that Sermorelin can improve outcomes for patients who suffer from cachexia as a result of AIDs Wasting Disease, Cancer Treatment, and even anorexia. Cachexia is medically defined as a loss of ten percent of more in body weight that is attributable to muscular atrophy.
Sermorelin AIDs Treatment
Patients who suffer from AIDs wasting disease lose the ability to preserve their muscle strength. There are many reasons for this. One reason is that patients lose their desire to eat, whether it be by the effects of medications that are taking to combat the disease or the effect of the disease itself. Another reason that AIDs patients suffer from muscle atrophy is because the progression of the AIDs virus can deteriorate the human body's natural ability to distribute nutrients effectively throughout the body. Sermorelin produces positive effects at both ends of this spectrum. For one thing, Sermorelin can produce metabolism and encourage hunger in patients that have trouble desiring food. In addition to this, the rejuvenating effects of Sermorelin restore the body's ability to distribute valuable nutrients throughout the body, giving the muscles the tools they need to rebuild themselves. Sermorelin Treatment can give AIDs patients the ability to live a more productive and healthy life in spite of their disease that many patients may not have been able to experience otherwise.
Sermorelin Cancer Treatment
Sermorelin is effective in cancer patients for similar reasons. Cancer treatments such as Radiation and Chemotherapy reduce the ability of healthy cells to proliferate as well as cancer cells. These forms of therapy also lead to nausea and sickness that make it harder to eat. Sermorelin restores hunger by increasing metabolism while also working to reverse some of the damage accumulated by radiation and chemotherapy. These positive effects on metabolism and growth persist in healthy cells even though the cancer therapy continues to kill off cancerous cells.
Sermorelin Anorexia Treatment
In patients who suffer from anorexia that is extreme enough to result in cachexia, Sermorelin can be used to restore muscle atrophy that resulted from the persisting eating disorder. Of course, Sermorelin therapy must be combined with other forms of physical, medical, and emotional therapy to relieve the underlying symptoms of anorexia, but Sermorelin is particularly effective at restoring atrophied muscles and returning them to a more healthy state.
How is Human Growth Hormone Deficiency Diagnosed?
After making the decision that Sermorelin Therapy might be right for you, there are three stages to receiving a diagnosis for HGH Deficiency:
Medical History Form
The first stage is that you must fill out a medical history form. This form will inform your physician of any ailments or issues you are having or have had in the past. It will inform your physician of any underlying issues that you may suffer from that may exacerbate your hormone deficiency. It will also provide information that will ensure that it is safe for you to go Sermorelin Therapy.
You will also need to undergo a physical. The physical will inform your prescribing physician of important factors such as your height, weight, and muscle/fat ratio which will allow him or her to prescribe you with a dose that will accurately suit your physical parameters. Sermorelin is a highly potent hormone, and it is very important that your prescribing doctor prescribe an accurate dose of the GH-RH analogue to suit your unique hormone needs.
Third, you will need to undergo Blood Testing. Your prescribing physician will set up an appointment with a highly respectable and efficient blood testing company such as LabCorp that can take your blood sample and run a thorough battery of tests which will provide a complete hormone panel so that your prescribing doctor has a significant amount of diagnostic information available to make an accurate and sensible diagnosis. It normally takes around five business days for the results of the bloodwork to reach your Anti-Aging physician for examination, but after your physician receives the blood diagnostics, he or she can quickly make a diagnosis.
Diagnosis and Prescription
If your Anti-Aging physician looks over all the available data and deems you an acceptable candidate for Sermorelin Acetate Therapy, he or she will write a prescription and discuss treatment protocols with you to ensure that you are fully informed about how to properly use Sermorelin. After you have received your prescription you can make an order for Sermorelin from a reputable pharmacy such as the one on this website. Our pharmacy can promptly and safely deliver Sermorelin to you via Federal Express. We have the logistical capabilities to send safely refrigerated and carefully handled Sermorelin Acetate Therapy to your doorstep by overnight delivery.
Who should not take Sermorelin?
Patients who are utilizing corticolsteroids such as hydrocortizone, dexamethazone, and prednisone may interact in a negative way with Sermorelin Therapy. In addition to this, patients who are currently prescribed medicines which treat hypothyroidism such as levothyroxine should exercise caution when considering Sermorelin. Always listen to your physician. You may be allowed to take these medications concurrently, but realize that there is an enhanced risk of side effect or negative reaction.
Unless prescribed expressly as a means to combat cachexia as a result of radiation and chemotherapy, Sermorelin should not be used while a patient has cancer, because under some circumstances, excess levels of Human Growth Hormone can contribute to cancer growth.
Unless she has been given express permission by a physician, a woman should avoid HGH and Sermorelin Therapy if she is pregnant. In animal tests in which purposeful overdoses were delivered to the mother, the fetus developed minor abnormality. With normal human treatment there is no indication the Sermorelin Therapy has a negative effect on the child, but there is not sufficient evidence available to claim that birth defects or growth abnormalities are not a possibility. Also, women who are in the process of nursing their child should not use Sermorelin without the approval of their doctor. To date, there has been no research conducted with regard to breast milk and Sermorelin.
Sermorelin Scams are Too Good to Be True Stick with Responsible Legal Pharmacies
There are hundreds if not thousands of imitators out there, but Sermorelin Therapy is only effective when delivered via subcutaneous injection. Fraudulent websites often try to pawn off pills and sprays as legitimate forms of therapy. Beware! These forms of Hormone Replacement Therapy are ineffective and can even damage your body if used for a long period of time. Patches are also a ripoff. Though Testosterone creams and patches can be extremely effective in treating Testosterone Deficiency, there is no cream or patch available today that can effectively treat Human Growth Hormone Deficiency.
It is also vitally important to only purchase Sermorelin Therapy or any other Hormone Replacement Therapy from Reputable dealers. There are countless websites, forums, and message boards which feature men and women selling or pretending to sell Sermorelin or other Hormone Replacement Therapies without a prescription. It is incredibly risky for multiple reasons to make black market deals for Sermorelin Therapy.
It is highly illegal to sell Sermorelin without a prescription. It is also just as illegal to purchase Sermorelin without a legally attained prescription. If you make an agreement to purchase black market Sermorelin and are caught by law enforcement officials, you will risk jail time and face significant fines as a result of your indiscretions.
Also, there is no guarantee as to the safety or strength of the product that you eventually receive. These black market forms of Hormone Therapies such as Sermorelin are often created in Central American and Chinese laboratories, if not simply domestic makeshift drug labs which combine dangerous chemicals with amateur chemists. At best you will receive an inferior product which provides only modest physical gains. At worst, you will receive a product that is actively dangerous to your body and can present life-threatening consequences with long-term usage.
Only Use Sermorelin with a Legitimate Deficiency
Physician-prescribed Sermorelin Therapy is incredibly effective in patients who truly display a need for Human Growth Hormone, and our Clinic is fully certified to legally provide Hormone Replacement Solutions for our patients. These therapies are safe and clinically effective, with little to no risk of adverse health effect. If you are interested in Sermorelin Acetate Therapy or any other Hormone Replacement Therapy that we provide, we urge you to give us a call today we would love to help you change the life of you or a loved one today, and we have the capability to do so.
Sermorelin Prescription Dosage
There are a number of variables that will affect your particular prescription for Sermorelin. Specific dosage is dependent upon your particular age as well as your sex. Also, different individuals who seem to be identical can be affected in significantly different ways by the same level of Human Growth Hormone Deficiency, so the prescription that you receive is also partially dependent upon the type and severity of symptoms that you display.
It is also vitally important to have your blood drawn at least twice a year while on Sermorelin therapy or any other form of Hormone Replacement Therapy in order to monitor the effectiveness of therapy and to ensure that no physiological abnormalities occur as a result of such therapy. If unwanted side-effects do occur, patient and physician can discuss options to adjust the current dosage or change therapies.
Try Sermorelin Today
Sermorelin Therapy is an amazing treatment option for those who suffer from Human Growth Hormone Deficiency. In spite of this fact, Sermorelin is not the right choice for every patient. Sermorelin is intended for individuals who still have the ability to secrete HGH at healthy levels, but are unable to due to a deficiency of Growth Hormone-Releasing Hormone. If it is discovered that your body does not respond to Sermorelin Therapy, we can discuss other therapies such as Human Growth Hormone Replacement Therapy to remedy your particular endocrine abnormality. We implore you to contact us today. We have the best therapies and techniques that modern science has to offer at our disposal, and we are driven to provide longer, healthier, and brighter futures to our patients. We can restore your waning vitality and provide you with the energy of your youth while maximizing the potential of your wisdom and experience.
The new Cutting-Edge Of Preventative Medicine
When we're young, ample amounts of growth hormone releasing factor are produced so that the pituitary is able to provide the body with sufficient growth hormone to sustain health and vitality. However, as we age, growth hormone releasing factor declines causing reduced production and secretion of pituitary HGH often leading to a growth hormone insufficiency that erodes health, and diminishes vigor and vitality. Restoring medical levels of growth hormone may improve or sustain good youthful anatomy, physiology, and thereby, the health and vitality often lost with age-related growth hormone deficiency. Traditionally, adult growth hormone deficiency (AGHD) has been treated by substituting natural HGH with recombinant human growth hormone (rhGH). Although rhGH injections are still the standard for treating AGHD, a breakthrough product, Sermorelin, offers a more natural, affordable alternative that is as effective as rhGH therapy.
Developed in 1998 by Serono Laboratories, Inc., the makers of Saizen HGH, FDA approved Sermorelin as recently become available for the treatment of AGHD. Sermorelin is comprised of 29 amino acids found in the hormone (GRF 1-44) that your brain produces naturally to simulate the release of HGH. As a growth hormone releasing agent, Sermorelin triggers the pituitary gland to produce your own natural HGH. In this natural process, your body regulates the level and frequency of HGH release, so there are no side effects associated with the constant application of injected rhGH. Sermorelin requires no off-cycles. In fact, the longer you use it, the better your pituitary gland functions, more like it did when you were younger.
Bottom line, Sermorelin effectively re-starts your natural HGH production to levels produced when you were younger. This not only provides the youth-restoring benefits of HGH on body composition, it also helps sustain pituitary health and opposes loss of activity of the endocrine system that normally occurs with age.
You should really know about Human Growth Hormone before thinking about taking HGH therapy. Human Growth Hormone is similar to estrogen and progesterone because it assists humans in growth. The anterior pituitary secretes Human Growth Hormones and the one hundred ninety one proteins that assist the body in its maturation and proper sequenced development.
HGH treatments consist of a manufactured version of GHGH (The releaser of HGH which sends the message toward the anterior pituitary to secrete HGH) and HGH. With particular folks GHRH becomes inhibited or dysfunctional and it will stop releasing signals properly. A failing GHRH can make a grown up start to get old too fast. Sermorelin injections can assist them in keeping the look of youth for longer.
Long R3-1 Sermorelin HGH is often provided to kids who lack it and are having trouble growing right. In recent years the Food and Drug Administration allowed Sermorelin to be given to people who feel they are getting older too fast. It can also be given to those who have HIW because it reduces a few issues related to that disease.
Sermorelin shots are every day, normally when it is time for bed. This will often make sleep better because hormones are secreted at their highest during sleep. Sex and level of aging are things that consider the level of dosage you are given.
The pros of having HRT include less lines and bouncier skin and higher energy. Those who have bone density problems will discover a difference too. Other pros are more strength and greater lean muscle, dropping a lot of fat in the tissues, higher sex-drive, and greater sex function capability.
A Sermorelin regimen is used by physicians to treat the kidneys. Physicians discovered that function of the kidneys is made stronger, and memory is stronger too. Problems with hypertension will likely lessen or be eliminated. The immune system can become stronger and it might make the hair grow back on your head and thicker.
There are some possible side effects, though, in combination with the benefits. The most reported is swelling and pain at the shot site. Other serious issues include problems swallowing and itchiness. Very rare but very serious issues that may arise are vomiting, hyperactivity, headache, and dizziness. These should be told to a doctor.
Anyone who thinks therapy with Sermorelin could be right for them should talk to a doctor about it. There are many physicians who are allowed to give the therapy all over the United States, and there exists many places that will be able to give therapy to all of those who have Hormone Deficiency Onset in Adulthood. Participants are monitored with care and testing. Laboratory work is used to guarantee that a person is benefiting properly. This is prescription-required therapy and could cost a person $2000-$3000.
HGH Treatment is a great way to assist those that have an HGH deficiency and look old too fast. It will also make their mind feel younger in addition to restoring a more youthful look.
Sermorelin Acetate Injections
Sermorelin is one of the most common injectable Hormonal supplementation therapies used today to increase IGF-1 production, and it works successfully by directly leading to the internal production of more Human Growth Hormone (HGH) circulating in the body. Sermorelin works as a secretegogue analog of the hormone Growth Hormone Releasing Hormone (GHRH) that tells the pituitary gland to release more HGH. In order to fully understand what Sermorelin is and how it works, it is important to fully understand why and how Human Growth Hormone is secreted from the pituitary gland and how it travels to the liver to stimulate IGF-1 production.
Injectable Sermorelin Replacement Therapy and the Pituitary Hypothalamic Axis
Sermorelin affects the body by not just releasing, but regulating HGH. It is an analog secretegogue hormone supplement that works in the same fashion as the hormone secretegogue Growth Hormone Releasing Hormone (GHRH), but more importantly it works with the hypothalamic pituitary complex which has checks and balances, whereas HGH injections alone, may not work as effectively with the hypothalamic pituitary axis.
Sermorelin Injections as an Affordable Hormone Treatment Program
These days we understand that hormones are essential to the regulation of the multitude of bodily functions. There can be significant medical and health problems when hormones are not secreted in the proper amounts, either too much or too little. This is doubly true for Growth Hormone and its essential precursor GHRH released from the hypothalamus. Many of the issues associated with decline hormones can also arise when the body is not properly releasing Growth Hormone Releasing Hormone (GHRH). This can lead to improper secretion of Growth Hormone. There are numerous reasons why the body doesn't produce enough HGH, one of the most significant reasons is thought to be as a result in declining GHRH and this is why Sermorelin, not just HGH therapy is so important.
Scientists Discovered the Human Body Can Secrete HGH at any Age, even "Old Age"
The body is perfectly capable of creating the proper amount of Growth Hormone, but when GHRH does not send the hormone chemical message to the anterior pituitary then it's time to supplement more of the hormone. Often, people need to take bio-identical genetically synthesized hormone supplementation like Sermorelin to raise hormone production up to normal levels, so that health issues can be alleviated or prevented. Injections of Sermorelin have been proven to be very effective at restoring youthfulness and keeping the body healthy.
Sermorelin Injection Doses By Hormone Physician Prescription
By using Sermorelin properly and with correct dosage, vigor, strength, healthier hair, improved skin and proper muscular function can be restored. There are a large number of potential benefits to using Sermorelin to assist in the regulation of Human Growth Hormone, and there are a number of conditions that Sermorelin is used to treat.
Injectable Sermorelin Benefits
It can reduce recovery time after injury or general physical activity, improve sleep, provide a rejuvenated sense of well being when waking up, reduce body fat, and alleviate depression. Some patients have reported that they had less gray hair growth. Most people report it reduces wrinkles, fine lines and thin saggy skin. These are just a few benefits that Sermorelin patients report.
Children and Sermorelin with Dwarfism or Short of Stature
There are health problems that occur in children where the production of Human Growth Hormone (HGH) is suppressed. These children often become afflicted with a condition known as dwarfism or short stature. They do not grow up like normal children do, and thus remain short for their entire lives.
Sermorelin is also FDA-approved for dwarfism. Sermorelin is also approved as a treatment for premature aging as well. For this reason, it is also possible that Sermorelin could treat rare disorders such as progeria, which cause children to grow physically old at a very fast rate. They pass away before they reach their thirties.
Sermorelin and AIDS: Muscle Wasting and Weight Balance
Sermorelin has also been shown to improve many symptoms associated with HIV in many cases, for instance reversing unhealthy muscle wasting and weight loss. Many people are overweight, but with AIDS, what often happens is people become underweight. Healthy weight is in the median of these two extremes. There are many ailments and illnesses that can be treated by Sermorelin and proper medical counseling is first required. These treatments can help patients live fit and productive lives that they would not have the opportunity to without treatment, presuming they are deficient in hormones, an inevitable part of aging.
Hormone Deficiency Testing and Lab Work for Sermorelin Therapy
Proper testing is needed to determine exactly how much Sermorelin an individual patient needs, if at all, deficiency is required or if you are continuing therapy. Sermorelin is administered through injection to maximize the effectiveness of the hormone, because there is no other way to administer it. Hundreds of web sites are hawking HGH or Sermorelin pills, sprays, patches and incense - these are unadulterated scams. Only through injections can Sermorelin be administered. The injections are performed at night before bed because this is the time at which the pituitary gland releases the most Human Growth Hormone, especially in the 7th and 8th hour of sleep. Sermorelin also provides a better night's sleep and alleviates the fatigue and irritability of those suffering from a growth hormone deficiency, while enhancing the individual's ability to become more engaged with life. One of the most significant things you will notice when you do sermorelin injections at night on an empty stomach is you wake up feeling very rejuvenated.
Sermorelin Injections Dosage
The specific dose of Sermorelin depends upon the sex of the individual as well as the age-related symptoms or medical conditions they are experiencing. The patient should be regularly monitored to make sure that the body is properly tolerating the dosage of Sermorelin that is being administered in private at home. By doing this, the doctor and patient can minimize side effects and discomfort that can be associated with taking too much Sermorelin.
The Most Obvious Benefits of Sermorelin Injections
Among the many benefits of using Sermorelin to treat patients with Human Growth Hormone deficiencies are smoother skin with fewer wrinkles, stronger muscles with more elasticity, and an overall increase in vigor and strength. Levels of unhealthy body fat also decrease, especially around the hard-to-treat midsection. Increased libido and sexual ability are also commonly recorded benefits to taking Sermorelin.
Sermorelin Injections and Internal Medicine
The immune system also becomes stronger, along with the filtration ability of the kidneys and the cognitive ability of the brain. Throughout treatment, one should regularly consult our endocrinologist and internal medicine physician about their Human Growth Hormone levels. They should inform our doctor of any and all discomfort and side-effects that they experience as they go through therapy. Each person has a different set of needs, and the effects of Sermorelin therapy will be different for every patient.
Injectable Sermorelin Prescription
Sermorelin is not available without prescription, and our hormone clinic has authorization to undertake and administer Sermorelin therapy, as well as other hormone therapy programs. Never choose a clinic that does not specialize in HRT. The patient should choose another provider for his or her own health and safety. We hope you will choose us as we are a reputable HRT medical clinic. Before starting Sermorelin therapy, have a thorough physical performed by your general practitioner or other health professional, then call us and we will schedule you to have a blood test. We specialize in hormone therapy and prescribe doses accurately.
Get Started With Sermorelin Acetate Injections
To learn more about Sermorelin or any other of our hormone treatment options, contact us today at Bio-Identical Hormone Replacement Therapy MD, the Conscious Evolution Medical Institute and ask to speak with one of our many clinical specialists.
Sermorelin isn't right for everyone, but it may be right for you. Sermorelin is used for those patients that are still able to properly produce Human Growth Hormone, but do so in diminished amounts. If the body is not capable of producing the hormone, we will discuss other treatment options with you such as direct Growth Hormone Therapy. Our staff has everything that you need to start a better life with Hormone Replacement Therapy!
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SERMORELIN ACETATE DIAGNOSTIC SOLUTION, RECONSTITUTED (RECON SOLN)