Japanese Study Shows Restorative Benefits of Testosterone
Hormone Treatments Show Great Potential to Increase Life Quality
On our Website we
talk a lot about the general benefits of Testosterone and HGH Hormone
Replacement Therapy, along with other forms of Hormone Treatment
which show great potential to increase the quality and length of our
New clinical studies
increase our knowledge regarding the immense Benefits of Hormone
Replacement, and recently, a new clinical study provided further
proof that Testosterone has the ability to improve both physical and
mental health in aging men dealing with the vitality-sapping
condition known as andropause.
Andropause is a
naturally occurring hormonal disorder that will eventually affect
every man at some point in his life. Andropause refers to the body's
gradual loss of ability to produce its own endogenous Testosterone,
leading to numerous negative health symptoms while also greatly
increasing the risk of a large number of medical conditions such as
heart attack, stroke, and cardiovascular disease.
In recent weeks, a
new study regarding the effectiveness of Testosterone Injections has
been released, increasing our knowledge about the tremendous
potential of Testosterone Hormone Replacement Therapy as a means to
safeguard physical and mental health.
This clinical trial
was populated by a pool of men suffering from Adult-Onset
Hypogonadism. Adult-Onset Hypogonadism is a scientific term which is
analogous to andropause. As a result of hormonal changes that occur
in the testes, anterior pituitary gland, and hypothalamus, the body
loses its ability to effectively synthesize and release healthy
levels of Testosterone throughout the body. Male Andropause is
usually primarily the result of changes in the Testes which prevent
the organs from properly releasing the vital male hormone.
In this study,
Testosterone Injections have been shown to increase a man's ability
to live a more engaged and active lifestyle in regard to both
emotional interaction and physical activity. Many people immediately
think of Testosterone as a hormone which promotes male physical
health, but Testosterone plays an immense role in male mental health
as well, promoting strong memory, cognitive sharpness, assertiveness,
and emotional stability.
The primary research
scientist spearheading this Testosterone Project is named Hiroyuki
Who is Hiroyuki
Konaka is a
scientist representing the University of Kanazawa that specializes in
urology and oncology, but has also done significant work related to
the field of endocrinology.
Konaka's study was
presented at the Annual Scientific Meeting of the American Urological
Association. The AUA is an American scientific organization and
lobbying entity that is committed to the ultimate goal of increasing
the effectiveness of Urological medical management. Although this may
seem unrelated to Testosterone Hormone Replacement Therapy,
Testosterone has been shown to have a significant effect upon both
prostate and urinary tract health in male patients.
Optimistic About Testosterone
study is incredibly promising, he is aware that there is a sustained
debate regarding the efficacy of Androgen Hormone Treatments as a
means to increase longevity and improve overall health outcomes. One
of the reasons that there is such debate is that in Western Science,
Testosterone Replacement has not been studied as vigorously as many
other medical treatments.
The West tends to
place maximum value upon treatments which cure or treat illness, and
places a lesser emphasis upon treatments which are intended to
prevent illness or prolong overall health. In the United States,
there have been a number of research studies regarding Testosterone
for Low-T, but most of these studies are brief and have only a fairly
small pool of participants.
Testosterone Study Provides a Wealth of Knowledge
There are three
primary ways in which this Testosterone Trial increases our knowledge
about the hormone treatment:
First, this study is
far larger than the vast majority of scientific studies regarding
Androgen Hormone Replacement, which vastly increases the ability to
confirm the results. Large participant populations increase the
sensitivity of statistical models and decrease noise in the data
which prevent researchers from staking firm claims.
Second, this is the
first randomized, large-scale Andropause study ever carried out
specifically regarding Asian patients. The scientific community is
becoming more and more aware of how the physiologies of different
ethnic groups share specific similarities and differences, and that
these differences can also apply to the body's sensitivity and
response to particular hormones such as Testosterone and Growth
Third, this is a
long term study, which is able to show how Youthful Testosterone
Levels affect the human physiology over time. Short term studies of
six months or less provide less evidence regarding the long term
benefits of Testosterone as well as potential negative responses to
long term therapy. This study was conducted over the course of a full
year, thus providing more time to show if the body either becomes
less actively affected by increased Testosterone or if certain
negative health consequences can result from long term use.
In this study, Dr.
Konaka and his associates selected a group of 334 males that were
clinically evaluated to suffer from Low-T. Specifically, the
threshold for Low Testosterone for this study was 11.8 pg/mL Free
Testosterone. This clinical study revolves around patients that are
suffering from a severe Testosterone Deficiency. The threshold for
Testosterone Deficiency in the United States is a Free Testosterone
Level of under 65 pg/mL or 3.2 pg/ml or less of Total Testosterone.
By studying patients with a severe deficiency, it makes it easier to
physiologically identify changes in health that take place.
The age range for
these participants in this study was between fifty and ninety years
Why Is This Age
Age is intricately
related to Testosterone Levels and Testosterone Decline. Testosterone
Levels naturally begin to drop around the age of thirty years old.
This decline is slow, but it builds quite tremendously over time. The
average male loses between one and two percent of their natural Free
Testosterone every year after the age of thirty.
Most patients don't
begin to feel the effects of this decline until they become a bit
older. Although many patients experience symptoms of Low-T in their
thirties, most patients begin experiencing significant issues related
to that decline during their early to mid-forties.
By choosing a client
pool which is essentially fifty and older, the researchers are able
to demonstrate what Testosterone can potentially do for a large and
stable segment of the population that is incredibly at risk for
complications as a result of flagging Testosterone Rates.
Konaka's study is a
double-blind study, meaning that the participant pool is divided into
two groups: An experimental group and a control group. 169 of the
participants belonged to the experimental group, and received
Testosterone Enanthate Injections in order to measure physiological
response over time.
The second group of
165 males received placebo and were not made aware of the fact. The
experimental group received a series of as many as twelve
Testosterone injections, one 250 mg dose once per month. Testosterone
Enanthate is one of the longest acting Testosterone Injections,
slowly releasing Testosterone into the body over the course of a
All patients in the
study were at least moderately healthy. They were measured using a
scale known as the Eastern Cooperative Oncology Group Performance
Status. All qualified participants measured either a zero, one, or
two in the exam, meaning that they had a full ability to walk, as
well as a total ability to live on their own without the aid of
another person to take care of them. The ECOG Performance Status is a
simple scale used by researchers and physicians in order to rate a
patient's physical capacity for activity.
This form of
Testosterone is a derivative of Endogenously Produced Testosterone,
biologically altered in order to provide a slow and sustained release
of Testosterone through the blood stream via the muscles.
Specifically, Testosterone Enanthate is comprised of
biologically-identical Testosterone chemically fused into an ester
compound and suspended within an oil solution, which is injected into
treatment is directly injected into the muscles via a method known as
Intramuscular Injection. Many hormones and medications are delivered
into the muscles, while other medicines, as well as Hormones like
HGH, are delivered just under the skin via a method known as
Subcutaneous Injection. Testosterone Enanthate is an anabolic
steroid, and in the United States it is defined as a Schedule Three
Controlled Substance. Testosterone Injections are only legal for use
via clinical need and medical prescription via physician.
Testosterone Study Results
After fifty two
weeks of injections, the males in the experimental group experienced
significant gains as a result of Testosterone Enanthate HRT. Patients
experienced the following benefits:
Increased Sexual Function (Sexual ability established via the International Index of Erectile Function.* Variables include the ability to establish a firm erection.)
Enhanced Muscle Strength
Normalized Urination, Decreased Frequency
Improved Physical Role Functioning
Elevated emotional levels (Established using SF-36**)
Patients in the
control group received absolutely no benefit from placebo, and as a
whole, the patients actually experience an increase in waist size
over the previous year, which is indicative of other declines in
physiological health as well.
IIEF-5 is a five item questionnaire which is used in order to
diagnose sexual dysfunction. The patient answers each of the five
items on a scale of one to five, one being the most indicative of
dysfunction, and five being the most indicative of dysfunction.
SF-36 is a thirty six question health survey that provides an eight
scale psychological and physical profile of health and well-being.
This survey is designed to be an indicator of general physiological
Popular in America than Japan
Testosterone Hormone Replacement is continually growing in popularity
in the United States and other Western nations, Testosterone HRT is
far less frequently utilized in Japan, largely because the Japanese
Universal Health Care Plan only covers Testosterone Injections,
rather than Testosterone Creams, Sprays, and Patches.
Although all of
these forms of Testosterone are effective, and each type has its own
benefits and drawbacks, many men are more averse to Testosterone
Injections because of needle anxiety or other reasons revolving
around relative ease-of-use.
Affect Different Ethnic Groups in Unique Ways
is some evidence that Testosterone Hormone Replacement may affect
different ethnic groups in different ways. Japanese men may take to
Testosterone Injections in certain manners that don't apply to
Europeans. For example, Japanese patients have been shown to respond
impressively to Testosterone as a treatment for prostate cancer,
whereas this link has not been established in patients of European
Study: Medical Conference Impact
Irwin Goldstein, MD,
was the presiding moderator of the session, and he felt that the
study made a profound impact on scientific knowledge regarding the
Effectiveness of Testosterone.
Who is Irwin
Goldstein is the
current leader of the Institute for Sexual Medicine, and is a leading
source regarding the effectiveness of Testosterone Hormone
Replacement. Goldstein's primary concern regarding Kanaka's study was
that fifty two weeks of treatment was arguably not a long term study,
but he found the overall results and benefits of the study to be
highly enlightening, nonetheless.
One of the
Goldstein's primary compliments regarding the study was that it
placed an emphasis on measuring the potential mental health benefits
of Testosterone. He was incredibly pleased that Kanaka and his
associates made the decision to measure both mood and cognition in
relation to Testosterone Replacement.
patients are certainly very concerned about their physical health and
longevity, most aging men are more concerned with their cognitive
health rather than their physical health. This concern only tends to
grow with age.
Regarding Japanese Andropause Study
This study showed
off a number of benefits regarding Testosterone Hormone Replacement
Therapy, and we will now take a moment to go into greater detail in
relation to these mentioned benefits:
Function With Testosterone
This is the most
commonly accepted benefit of Testosterone Therapy. Testosterone is
intricately tied with all of the normal physiological processes
associated with sexual activity in males (and Testosterone is
intricately related to sexual desire and ability in female patients
as well). Testosterone is released at its highest rates during
periods of sexual arousal, and without Testosterone, sexual activity
is actually entirely impossible for males.
controls libido, sexual ability, and sexual potency. Without
appropriate Testosterone Levels, men lose interest in sex, lose the
ability to support and maintain an erection, and their fertility
becomes severely impacted as well. Testosterone Creams and Injections
are the most effective way to restore everything sexual in male
patients suffering from nearly any form of sexual dysfunction.
Strength With Testosterone
Andropause Clinical Research also demonstrates the benefits that
Testosterone provides the muscles. Testosterone is a potent anabolic
steroid which stimulates muscle health, size and strength. Man's
increased Testosterone levels in relation to women is directly
responsible for the significant differences in musculature between
the two sexes.
For patients that
have Testosterone Deficiency, a quality Testosterone Replacement
Therapy regimen can preserve muscle health and prevent the natural
muscle atrophy that is a direct result of the aging process and
andropause. Testosterone Treatments can also contribute to
significant gains in muscle strength and volume when combined with a
healthy workout regimen.
Urination, Decreased Frequency with Testosterone
are intricately tied to prostate health. As Testosterone Levels start
to decline, the prostate begins to increase in size, applying
pressure on the bladder and kidneys which decrease the volume of
urination while increasing the frequency. Testosterone Replacement
Therapy relieves this pressure on the urinary tract, allowing male
patients to maintain more streamlined urological health.
Role Functioning with Testosterone
Testosterone has the
ability to restore overall physical health in patients that suffer
from Testosterone Deficiency. There are a number of symptoms of Low-T
that are related to decline in muscle health, as well as numerous
other factors, which impact a person's physical ability to enjoy
their life and manage their health.
Emotional Health with Testosterone
Deficiency has a powerful impact upon general emotional health.
Testosterone is largely responsible for a number of different factors
which contribute to male personality and mental health. Testosterone
contributes to male assertiveness and dominance, and Testosterone
Deficiency can severely restrict a man's ability to make the most of
his masculine traits. Low Testosterone has also been tightly
correlated with depression and anxiety in male patients, and
Testosterone Replacement has been shown to alleviate mild to moderate
feelings of both anxiousness and depression.
In male patients,
one of the most direct indicators of overall physical health is the
circumference of the waist. Individuals that have higher-than-normal
waist circumference have an increased risk of a number of different
medical disorders. This distended belly shape is indicative of both
poor nutrition and poor exercise habits.
The size of the
belly and waist is controlled by two factors. Exercise promotes
stronger muscles which decrease waist size, and adipose fat collects
primarily on the hips, butt, waist, and stomach. High levels of this
form of body fat are correlated with everything from diabetes to
heart disease, and high levels of fat actually contribute to
Testosterone Deficiency, exacerbating the effects and greatly
increasing the risk of complications related to that deficiency.
Testosterone Deficiency with the Conscious Evolution Institute
This study further
confirms numerous medical issues that we have discussed on our
website, and only serves to further illuminate the immense benefits
provided by Testosterone HRT and other forms of Hormone Replacement
If you feel that you
are suffering from the symptoms of Low-T, we encourage you to call or
contact the Conscious Evolution Institute today. We can answer any
questions that you have about our highly beneficial health regimens,
and can set you up with an appointment with a local medical affiliate
that can get you started as soon as is convenient for you!