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Japanese Study Shows Restorative Benefits of Testosterone


Recommended by Dr. Di Santo, Published on 30 September 2017

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Japanese Study Shows Restorative Benefits of Testosterone

Testosterone Hormone Treatments Show Great Potential to Increase Life Quality

On our Website we talk a lot about the general benefits of Testosterone and HGH Hormone Replacement Therapy, along with other forms of Hormone Treatment which show great potential to increase the quality and length of our lives.

New clinical studies increase our knowledge regarding the immense Benefits of Hormone Replacement, and recently, a new clinical study provided further proof that Testosterone has the ability to improve both physical and mental health in aging men dealing with the vitality-sapping condition known as andropause.

What is Andropause?

Andropause is a naturally occurring hormonal disorder that will eventually affect every man at some point in his life. Andropause refers to the body's gradual loss of ability to produce its own endogenous Testosterone, leading to numerous negative health symptoms while also greatly increasing the risk of a large number of medical conditions such as heart attack, stroke, and cardiovascular disease.

Japanese Testosterone Study

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In recent weeks, a new study regarding the effectiveness of Testosterone Injections has been released, increasing our knowledge about the tremendous potential of Testosterone Hormone Replacement Therapy as a means to safeguard physical and mental health.

This clinical trial was populated by a pool of men suffering from Adult-Onset Hypogonadism. Adult-Onset Hypogonadism is a scientific term which is analogous to andropause. As a result of hormonal changes that occur in the testes, anterior pituitary gland, and hypothalamus, the body loses its ability to effectively synthesize and release healthy levels of Testosterone throughout the body. Male Andropause is usually primarily the result of changes in the Testes which prevent the organs from properly releasing the vital male hormone.

In this study, Testosterone Injections have been shown to increase a man's ability to live a more engaged and active lifestyle in regard to both emotional interaction and physical activity. Many people immediately think of Testosterone as a hormone which promotes male physical health, but Testosterone plays an immense role in male mental health as well, promoting strong memory, cognitive sharpness, assertiveness, and emotional stability.

The primary research scientist spearheading this Testosterone Project is named Hiroyuki Konaka.

Who is Hiroyuki Konaka?

Konaka is a scientist representing the University of Kanazawa that specializes in urology and oncology, but has also done significant work related to the field of endocrinology.

Konaka's study was presented at the Annual Scientific Meeting of the American Urological Association. The AUA is an American scientific organization and lobbying entity that is committed to the ultimate goal of increasing the effectiveness of Urological medical management. Although this may seem unrelated to Testosterone Hormone Replacement Therapy, Testosterone has been shown to have a significant effect upon both prostate and urinary tract health in male patients.

Konaka Cautiously Optimistic About Testosterone

Although Konaka's study is incredibly promising, he is aware that there is a sustained debate regarding the efficacy of Androgen Hormone Treatments as a means to increase longevity and improve overall health outcomes. One of the reasons that there is such debate is that in Western Science, Testosterone Replacement has not been studied as vigorously as many other medical treatments.

The West tends to place maximum value upon treatments which cure or treat illness, and places a lesser emphasis upon treatments which are intended to prevent illness or prolong overall health. In the United States, there have been a number of research studies regarding Testosterone for Low-T, but most of these studies are brief and have only a fairly small pool of participants.

Asian Testosterone Study Provides a Wealth of Knowledge

There are three primary ways in which this Testosterone Trial increases our knowledge about the hormone treatment:

First, this study is far larger than the vast majority of scientific studies regarding Androgen Hormone Replacement, which vastly increases the ability to confirm the results. Large participant populations increase the sensitivity of statistical models and decrease noise in the data which prevent researchers from staking firm claims.

Second, this is the first randomized, large-scale Andropause study ever carried out specifically regarding Asian patients. The scientific community is becoming more and more aware of how the physiologies of different ethnic groups share specific similarities and differences, and that these differences can also apply to the body's sensitivity and response to particular hormones such as Testosterone and Growth Hormone.

Third, this is a long term study, which is able to show how Youthful Testosterone Levels affect the human physiology over time. Short term studies of six months or less provide less evidence regarding the long term benefits of Testosterone as well as potential negative responses to long term therapy. This study was conducted over the course of a full year, thus providing more time to show if the body either becomes less actively affected by increased Testosterone or if certain negative health consequences can result from long term use.

Testosterone Study Specifics

In this study, Dr. Konaka and his associates selected a group of 334 males that were clinically evaluated to suffer from Low-T. Specifically, the threshold for Low Testosterone for this study was 11.8 pg/mL Free Testosterone. This clinical study revolves around patients that are suffering from a severe Testosterone Deficiency. The threshold for Testosterone Deficiency in the United States is a Free Testosterone Level of under 65 pg/mL or 3.2 pg/ml or less of Total Testosterone. By studying patients with a severe deficiency, it makes it easier to physiologically identify changes in health that take place.

The age range for these participants in this study was between fifty and ninety years old.

Why Is This Age Range Important?

Age is intricately related to Testosterone Levels and Testosterone Decline. Testosterone Levels naturally begin to drop around the age of thirty years old. This decline is slow, but it builds quite tremendously over time. The average male loses between one and two percent of their natural Free Testosterone every year after the age of thirty.

Most patients don't begin to feel the effects of this decline until they become a bit older. Although many patients experience symptoms of Low-T in their thirties, most patients begin experiencing significant issues related to that decline during their early to mid-forties.

By choosing a client pool which is essentially fifty and older, the researchers are able to demonstrate what Testosterone can potentially do for a large and stable segment of the population that is incredibly at risk for complications as a result of flagging Testosterone Rates.

Double-Blind Testosterone Research

Konaka's study is a double-blind study, meaning that the participant pool is divided into two groups: An experimental group and a control group. 169 of the participants belonged to the experimental group, and received Testosterone Enanthate Injections in order to measure physiological response over time.

The second group of 165 males received placebo and were not made aware of the fact. The experimental group received a series of as many as twelve Testosterone injections, one 250 mg dose once per month. Testosterone Enanthate is one of the longest acting Testosterone Injections, slowly releasing Testosterone into the body over the course of a month.

All patients in the study were at least moderately healthy. They were measured using a scale known as the Eastern Cooperative Oncology Group Performance Status. All qualified participants measured either a zero, one, or two in the exam, meaning that they had a full ability to walk, as well as a total ability to live on their own without the aid of another person to take care of them. The ECOG Performance Status is a simple scale used by researchers and physicians in order to rate a patient's physical capacity for activity.

Testosterone Enanthate Information

This form of Testosterone is a derivative of Endogenously Produced Testosterone, biologically altered in order to provide a slow and sustained release of Testosterone through the blood stream via the muscles. Specifically, Testosterone Enanthate is comprised of biologically-identical Testosterone chemically fused into an ester compound and suspended within an oil solution, which is injected into the muscles.

This hormone treatment is directly injected into the muscles via a method known as Intramuscular Injection. Many hormones and medications are delivered into the muscles, while other medicines, as well as Hormones like HGH, are delivered just under the skin via a method known as Subcutaneous Injection. Testosterone Enanthate is an anabolic steroid, and in the United States it is defined as a Schedule Three Controlled Substance. Testosterone Injections are only legal for use via clinical need and medical prescription via physician.

Japanese Testosterone Study Results

After fifty two weeks of injections, the males in the experimental group experienced significant gains as a result of Testosterone Enanthate HRT. Patients experienced the following benefits:

  • Increased Sexual Function (Sexual ability established via the International Index of Erectile Function.* Variables include the ability to establish a firm erection.)

  • Enhanced Muscle Strength

  • Normalized Urination, Decreased Frequency

  • Improved Physical Role Functioning

  • Elevated emotional levels (Established using SF-36**)

  • Smaller Waist

Patients in the control group received absolutely no benefit from placebo, and as a whole, the patients actually experience an increase in waist size over the previous year, which is indicative of other declines in physiological health as well.

* The IIEF-5 is a five item questionnaire which is used in order to diagnose sexual dysfunction. The patient answers each of the five items on a scale of one to five, one being the most indicative of dysfunction, and five being the most indicative of dysfunction.

** The SF-36 is a thirty six question health survey that provides an eight scale psychological and physical profile of health and well-being. This survey is designed to be an indicator of general physiological health.

Testosterone More Popular in America than Japan

Although Testosterone Hormone Replacement is continually growing in popularity in the United States and other Western nations, Testosterone HRT is far less frequently utilized in Japan, largely because the Japanese Universal Health Care Plan only covers Testosterone Injections, rather than Testosterone Creams, Sprays, and Patches.

Although all of these forms of Testosterone are effective, and each type has its own benefits and drawbacks, many men are more averse to Testosterone Injections because of needle anxiety or other reasons revolving around relative ease-of-use.

Testosterone May Affect Different Ethnic Groups in Unique Ways

Surprisingly, there is some evidence that Testosterone Hormone Replacement may affect different ethnic groups in different ways. Japanese men may take to Testosterone Injections in certain manners that don't apply to Europeans. For example, Japanese patients have been shown to respond impressively to Testosterone as a treatment for prostate cancer, whereas this link has not been established in patients of European descent.

Japanese Low-T Study: Medical Conference Impact

Irwin Goldstein, MD, was the presiding moderator of the session, and he felt that the study made a profound impact on scientific knowledge regarding the Effectiveness of Testosterone.

Who is Irwin Goldstein?

Goldstein is the current leader of the Institute for Sexual Medicine, and is a leading source regarding the effectiveness of Testosterone Hormone Replacement. Goldstein's primary concern regarding Kanaka's study was that fifty two weeks of treatment was arguably not a long term study, but he found the overall results and benefits of the study to be highly enlightening, nonetheless.

One of the Goldstein's primary compliments regarding the study was that it placed an emphasis on measuring the potential mental health benefits of Testosterone. He was incredibly pleased that Kanaka and his associates made the decision to measure both mood and cognition in relation to Testosterone Replacement.

Although older patients are certainly very concerned about their physical health and longevity, most aging men are more concerned with their cognitive health rather than their physical health. This concern only tends to grow with age.

Thoughts Regarding Japanese Andropause Study

This study showed off a number of benefits regarding Testosterone Hormone Replacement Therapy, and we will now take a moment to go into greater detail in relation to these mentioned benefits:

Increased Sexual Function With Testosterone

This is the most commonly accepted benefit of Testosterone Therapy. Testosterone is intricately tied with all of the normal physiological processes associated with sexual activity in males (and Testosterone is intricately related to sexual desire and ability in female patients as well). Testosterone is released at its highest rates during periods of sexual arousal, and without Testosterone, sexual activity is actually entirely impossible for males.

Testosterone controls libido, sexual ability, and sexual potency. Without appropriate Testosterone Levels, men lose interest in sex, lose the ability to support and maintain an erection, and their fertility becomes severely impacted as well. Testosterone Creams and Injections are the most effective way to restore everything sexual in male patients suffering from nearly any form of sexual dysfunction.

Enhanced Muscle Strength With Testosterone

This Japanese Andropause Clinical Research also demonstrates the benefits that Testosterone provides the muscles. Testosterone is a potent anabolic steroid which stimulates muscle health, size and strength. Man's increased Testosterone levels in relation to women is directly responsible for the significant differences in musculature between the two sexes.

For patients that have Testosterone Deficiency, a quality Testosterone Replacement Therapy regimen can preserve muscle health and prevent the natural muscle atrophy that is a direct result of the aging process and andropause. Testosterone Treatments can also contribute to significant gains in muscle strength and volume when combined with a healthy workout regimen.

Normalized Urination, Decreased Frequency with Testosterone

Testosterone Levels are intricately tied to prostate health. As Testosterone Levels start to decline, the prostate begins to increase in size, applying pressure on the bladder and kidneys which decrease the volume of urination while increasing the frequency. Testosterone Replacement Therapy relieves this pressure on the urinary tract, allowing male patients to maintain more streamlined urological health.

Improved Physical Role Functioning with Testosterone

Testosterone has the ability to restore overall physical health in patients that suffer from Testosterone Deficiency. There are a number of symptoms of Low-T that are related to decline in muscle health, as well as numerous other factors, which impact a person's physical ability to enjoy their life and manage their health.

Increased Emotional Health with Testosterone

Testosterone Deficiency has a powerful impact upon general emotional health. Testosterone is largely responsible for a number of different factors which contribute to male personality and mental health. Testosterone contributes to male assertiveness and dominance, and Testosterone Deficiency can severely restrict a man's ability to make the most of his masculine traits. Low Testosterone has also been tightly correlated with depression and anxiety in male patients, and Testosterone Replacement has been shown to alleviate mild to moderate feelings of both anxiousness and depression.

Reduced Waist Size

In male patients, one of the most direct indicators of overall physical health is the circumference of the waist. Individuals that have higher-than-normal waist circumference have an increased risk of a number of different medical disorders. This distended belly shape is indicative of both poor nutrition and poor exercise habits.

The size of the belly and waist is controlled by two factors. Exercise promotes stronger muscles which decrease waist size, and adipose fat collects primarily on the hips, butt, waist, and stomach. High levels of this form of body fat are correlated with everything from diabetes to heart disease, and high levels of fat actually contribute to Testosterone Deficiency, exacerbating the effects and greatly increasing the risk of complications related to that deficiency.

Resolve Testosterone Deficiency with the Conscious Evolution Institute

This study further confirms numerous medical issues that we have discussed on our website, and only serves to further illuminate the immense benefits provided by Testosterone HRT and other forms of Hormone Replacement Therapy.

If you feel that you are suffering from the symptoms of Low-T, we encourage you to call or contact the Conscious Evolution Institute today. We can answer any questions that you have about our highly beneficial health regimens, and can set you up with an appointment with a local medical affiliate that can get you started as soon as is convenient for you!

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Three sided solution: Testosterone + HCG + Arimidex

If your doctor only prescribes testosterone by itself, you will probably have a rough ride. The tendency is for you to feel great the first couple months, while you increase testosterone levels, followed by a slow deterioration, once your estrogen creeps up.

High estrogen negates a lot of the positives from testosterone therapy, resulting in the same symptoms of low testosterone you had in the first place!

The solution is to add a drug called Arimidex. It's called an aromatase inhibitor, which essentially blocks the conversion of testosterone to estrogen. It has the effect of increasing testosterone levels, while keeping your estrogen low.

Once you have your testosterone and estrogen solved, it's time to stop the next inevitable decline? Shrinking testicles.

This is where HCG (human chorionic gonadotropin) comes in. It prevents both infertility and testicle shrinkage. Your testicles shrink because your body thinks it doesn't need to make testosterone anymore.

For some, small testicles may seem like just a cosmetic problem. But HGC does more than increase testicle size, it also increases adrenal function, which can have positive effects on well-being, libido, and energy.





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